The consensus-Based approach for gene/enzyme replacement therapies and crystallization strategies: The case of human alanine-Glyoxylate aminotransferase

Biochemical Journal

Volumn 462, Issue 3, 2014, Pages 453-463

  Mesa Torres, Noel ^a   Yunta, Cristina ^b   Fabelo Rosa, Israel ^c   Gonzalez Rubio, Juana María ^b   Sánchez Ruiz, José M ^a   Salido, Eduardo ^c   Albert, Armando ^b   Pey, Angel L ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

^c UNIVERSIDAD DE LA LAGUNA   (Spain)

Author keywords

Inherited disease; Protein crystallization; Protein function; Protein stability; Sequence alignment statistics; Therapy

Indexed keywords

ALANINE GLYOXYLATE AMINOTRANSFERASE; PROTEIN SERINE THREONINE KINASE; SALT OVERLY SENSITIVE 2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHO CELL LINE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; ENZYME ACTIVITY; ENZYME REPLACEMENT; ENZYME STABILITY; FEMALE; IN VITRO STUDY; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STABILITY; SEQUENCE ALIGNMENT; STATIC ELECTRICITY;

ANIMALS; CHO CELLS; CRICETULUS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; ENZYME REPLACEMENT THERAPY; ENZYME STABILITY; HUMANS; HYPEROXALURIA, PRIMARY; SEQUENCE ALIGNMENT; SOLUBILITY; TRANSAMINASES;

EID: 84907358194     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140250     Document Type: Article

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