Crystal structures of complexes of the branched-chain aminotransferase from deinococcus radiodurans with α-Ketoisocaproate and L-glutamate suggest the radiation resistance of this enzyme for catalysis

Journal of Bacteriology

Volumn 194, Issue 22, 2012, Pages 6206-6216

  Chen, Chung De ^a,b   Lin, Chih Hao ^c   Chuankhayan, Phimonphan ^a   Huang, Yen Chieh ^a   Hsieh, Yin Cheng ^a   Huang, Tien Feng ^a,b   Guan, Hong Hsiang ^a   Liu, Ming Yih ^a   Chang, Wen Chang ^c   Chena, Chun Jung ^a,b,d  

^a NATIONAL SYNCHROTRON RADIATION RESEARCH CENTER   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOISOCAPROIC ACID; BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE; GLUTAMIC ACID;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; DEINOCOCCUS RADIODURANS; ENZYME ACTIVITY; ENZYME SPECIFICITY; ESCHERICHIA COLI; HYDROGEN BOND; IONIZING RADIATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RADIOSENSITIVITY; THERMOSTABILITY;

AMINO ACID SEQUENCE; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DEINOCOCCUS; ENZYME STABILITY; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMIC ACID; KETO ACIDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SPECTROPHOTOMETRY; SUBSTRATE SPECIFICITY; TRANSAMINASES;

DEINOCOCCUS RADIODURANS; ESCHERICHIA COLI; THERMUS THERMOPHILUS;

EID: 84869123687     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.01659-12     Document Type: Article

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