Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy

Science Translational Medicine

Volumn 8, Issue 362, 2016, Pages

  Oubaha, Malika ^a,b   Miloudi, Khalil ^b   Dejda, Agnieszka ^a   Guber, Vera ^a   Mawambo, Gaëlle ^a   Germain, Marie Anne ^a   Bourdel, Guillaume ^a   Popovic, Natalija ^a   Rezende, Flavio A ^a   Kaufman, Randal J ^c   Mallette, Frédérick A ^a   Sapieha, Przemyslaw ^a,b  

^a UNIVERSITY OF MONTREAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENZYME; INOSITOL REQUIRING ENZYME 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; METFORMIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SEMAPHORIN 3A; UNCLASSIFIED DRUG; VASCULOTROPIN; CYTOKINE; ERN1 PROTEIN, HUMAN; OXYGEN; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; VASCULOTROPIN A;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL AGING; CELL HYPOXIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENETIC DISORDER; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; METABOLIC DISORDER; MIDDLE AGED; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PARACRINE SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROLIFERATIVE DIABETIC RETINOPATHY; RETINA CELL; RETINA ISCHEMIA; RETINA NEOVASCULARIZATION; SENESCENCE; SENESCENCE ASSOCIATED SECRETORY PHENOTYPE; TRANSCRIPTOMICS; VERY ELDERLY; VITREOUS BODY; ANIMAL; BLOOD; C57BL MOUSE; CELL PROLIFERATION; CHEMISTRY; DIABETIC RETINOPATHY; HEK293 CELL LINE; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PATHOPHYSIOLOGY; RETINA; RETINA BLOOD VESSEL; TUMOR CELL LINE; VITRECTOMY;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CELLULAR SENESCENCE; CYTOKINES; DIABETIC RETINOPATHY; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FEMALE; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; OXYGEN; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; RETINA; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITRECTOMY;

EID: 84993927167     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaf9440     Document Type: Article

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