The deletion of Math5 disrupts retinal blood vessel and glial development in mice

Experimental Eye Research

Volumn 96, Issue 1, 2012, Pages 147-156

  Edwards, Malia M ^a   McLeod, D Scott ^a   Li, Renzhong ^b,c   Grebe, Rhonda ^a   Bhutto, Imran ^a   Mu, Xiuqian ^b,c,d   Lutty, Gerard A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c SUNY EYE INSTITUTE   (United States)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Angiogenesis; Ganglion cells; Math5; Persistent fetal vasculature; Retina

Indexed keywords

CELL PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; ISOLECTIN B4; MATH5 PROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DISRUPTION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CHORION; CONTROLLED STUDY; GENE DELETION; GLIA; IMMUNOHISTOCHEMISTRY; MOUSE; MUELLER CELL; NERVE FIBER; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA BLOOD VESSEL; RETINA CAPILLARY; RETINA GANGLION CELL; TRANSMISSION ELECTRON MICROSCOPY; VITREOUS BODY;

ANIMALS; ANIMALS, NEWBORN; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE DELETION; GENOTYPING TECHNIQUES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; NERVE FIBERS; NERVE TISSUE PROTEINS; NEUROGLIA; PERSISTENT HYPERPLASTIC PRIMARY VITREOUS; PLANT LECTINS; RETINAL GANGLION CELLS; RETINAL NEOVASCULARIZATION; RETINAL VESSELS;

EID: 84863395028     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2011.12.005     Document Type: Article

References (27)

1. Baba T., Grebe R., Hasegawa T., Bhutto I., Merges C., McLeod D.S., Lutty G.A. Maturation of the fetal human choriocapillaris. Invest. Ophthalmol. Vis. Sci. 2009, 50:3503-3511.
2. Baba T., Bhutto I.A., Merges C., Grebe R., Emmert D., McLeod D.S., Armstrong D., Lutty G.A. A rat model for choroidal neovascularization using subretinal lipid hydroperoxide injection. Am. J. Pathol. 2010, 176:3085-3097.
3. Brown N.L., Patel S., Brzezinski J., Glaser T. Math5 is required for retinal ganglion cell and optic nerve formation. Development 2001, 128:2497-2508.
4. Carmeliet P. Blood vessels and nerves: common signals, pathways and diseases. Nat. Rev. Genet. 2003, 4:710-720.
5. Chan-Ling T., McLeod D.S., Hughes S., Baxter L., Chu Y., Hasegawa T., Lutty G.A. Astrocyte-endothelial cell relationships during human retinal vascular development. Invest. Ophthalmol. Vis. Sci. 2004, 45:2020-2032.
6. Dorrell M.I., Aguilar E., Friedlander M. Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion. Invest. Ophthalmol. Vis. Sci. 2002, 43:3500-3510.
7. Edwards M.M., Mammadova-Bach E., Alpy F., Klein A., Hicks W.L., Roux M., Simon-Assmann P., Smith R.S., Orend G., Wu J., Peachey N.S., Naggert J.K., Lefebvre O., Nishina P.M. Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation. J. Biol. Chem. 2010, 285:7697-7711.
8. Edwards M.M., McLeod D.S., Grebe R., Heng C., Lefebvre O., Lutty G.A. Lama1 mutations lead to vitreoretinal blood vessel formation, persistence of fetal vasculature, and epiretinal membrane formation in mice. BMC Dev. Biol. 2011, 11:60.
9. Fruttiger M., Calver A.R., Kruger W.H., Mudhar H.S., Michalovich D., Takakura N., Nishikawa S., Richardson W.D. PDGF mediates a neuron-astrocyte interaction in the developing retina. Neuron 1996, 17:1117-1131.
10. Fu X., Kiyama T., Li R., Russell M., Klein W.H., Mu X. Epitope-tagging Math5 and Pou4f2: new tools to study retinal ganglion cell development in the mouse. Dev. Dyn. Sep. 2009, 238(9):2309-2317.
11. Fukushima Y., Okada M., Kataoka H., Hirashima M., Yoshida Y., Mann F., Gomi F., Nishida K., Nishikawa S., Uemura A. Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. J. Clin. Invest. 2011, 121:1974-1985.
12. Ghiasvand N.M., Rudolph D.D., Mashayekhi M., Brzezinski J.A., Goldman D., Glaser T. Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease. Nat. Neurosci. 2011, 14(5):578-586. Epub 2011 Mar 27.
13. Hasegawa T., McLeod D.S., Prow T., Merges C., Grebe R., Lutty G.A. Vascular precursors in developing human retina. Invest. Ophthalmol. Vis. Sci. 2008, 49:2178-2192.
14. Hendrickson A., Djajadi H., Erickson A., Possin D. Development of the human retina in the absence of ganglion cells. Exp. Eye Res. 2006, 83:920-931.
15. Joyal J.S., Sitaras N., Binet F., Rivera J.C., Stahl A., Zaniolo K., Shao Z., Polosa A., Zhu T., Hamel D., Djavari M., Kunik D., Honore J.C., Picard E., Zabeida A., Varma D.R., Hickson G., Mancini J., Klagsbrun M., Costantino S., Beausejour C., Lachapelle P., Smith L.E., Chemtob S., Sapieha P. Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A. Blood 2011, 117:6024-6035.
16. Kim J.H., Yu Y.S., Kim K.W. Impaired retinal vascular development in anencephalic human fetus. Histochem. Cell Biol. 2010, 134:277-284.
17. Lazrak M., Deleuze V., Noel D., Haouzi D., Chalhoub E., Dohet C., Robbins I., Mathieu D. The bHLH TAL-1/SCL regulates endothelial cell migration and morphogenesis. J. Cell Sci. 2004, 117:1161-1171.
18. Le T.T., Wroblewski E., Patel S., Riesenberg A.N., Brown N.L. Math5 is required for both early retinal neuron differentiation and cell cycle progression. Dev. Biol. 2006, 295:764-778.
19. McLeod D.S., Lutty G.A., Wajer S.D., Flower R.W. Visualization of a developing vasculature. Microvasc. Res. 1987, 33:257-269.
20. McLeod D.S., Hasegawa T., Prow T., Merges C., Lutty G. The initial fetal human retinal vasculature develops by vasculogenesis. Dev. Dyn. 2006, 235:3336-3347.
21. Moshiri A., Gonzalez E., Tagawa K., Maeda H., Wang M., Frishman L.J., Wang S.W. Near complete loss of retinal ganglion cells in the math5/brn3b double knockout elicits severe reductions of other cell types during retinal development. Dev. Biol. 2008, 316:214-227.
22. Mukouyama Y.S., Shin D., Britsch S., Taniguchi M., Anderson D.J. Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin. Cell 2002, 109:693-705.
23. Saint-Geniez M., D'Amore P.A. Development and pathology of the hyaloid, choroidal and retinal vasculature. Int. J. Dev. Biol. 2004, 48:1045-1058.
24. Sapieha P., Sirinyan M., Hamel D., Zaniolo K., Joyal J.S., Cho J.H., Honore J.C., Kermorvant-Duchemin E., Varma D.R., Tremblay S., Leduc M., Rihakova L., Hardy P., Klein W.H., Mu X., Mamer O., Lachapelle P., Di Polo A., Beausejour C., Andelfinger G., Mitchell G., Sennlaub F., Chemtob S. The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis. Nat. Med. 2008, 14:1067-1076.
25. Wang S.W., Kim B.S., Ding K., Wang H., Sun D., Johnson R.L., Klein W.H., Gan L. Requirement for math5 in the development of retinal ganglion cells. Genes Dev. 2001, 15:24-29.
26. Watanabe T., Raff M.C. Retinal astrocytes are immigrants from the optic nerve. Nature 1988, 332:834-837.
27. Zhang C., Gehlbach P., Gongora C., Cano M., Fariss R., Hose S., Nath A., Green W.R., Goldberg M.F., Zigler J.S., Sinha D. A potential role for beta- and gamma-crystallins in the vascular remodeling of the eye. Dev. Dyn. 2005, 234:36-47.