-
1
-
-
59849104241
-
Molecular pathology of age-related macular degeneration
-
Ding X, Patel M, Chan CC (2009) Molecular pathology of age-related macular degeneration. Prog Retin Eye Res 28(1):1-18.
-
(2009)
Prog Retin Eye Res
, vol.28
, Issue.1
, pp. 1-18
-
-
Ding, X.1
Patel, M.2
Chan, C.C.3
-
2
-
-
34848892120
-
Epidemiology of cataract: Accomplishments over 25 years and future directions
-
West S (2007) Epidemiology of cataract: Accomplishments over 25 years and future directions. Ophthalmic Epidemiol 14(4):173-178.
-
(2007)
Ophthalmic Epidemiol
, vol.14
, Issue.4
, pp. 173-178
-
-
West, S.1
-
3
-
-
63049133469
-
Diabetic retinopathy: A growing concern in an aging population
-
Paulus YM, Gariano RF (2009) Diabetic retinopathy: A growing concern in an aging population. Geriatrics 64(2):16-20.
-
(2009)
Geriatrics
, vol.64
, Issue.2
, pp. 16-20
-
-
Paulus, Y.M.1
Gariano, R.F.2
-
4
-
-
56549118858
-
Risk factors for glaucoma onset and progression
-
Coleman AL, Miglior S (2008) Risk factors for glaucoma onset and progression. Surv Ophthalmol 53(Suppl1):S3-S10.
-
(2008)
Surv Ophthalmol
, vol.53
, pp. S3-S10
-
-
Coleman, A.L.1
Miglior, S.2
-
6
-
-
62649096850
-
Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: Implications for glaucoma
-
Carbone MA, et al. (2009) Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: Implications for glaucoma. PLoS One 4(1):e4216.
-
(2009)
PLoS One
, vol.4
, Issue.1
, pp. e4216
-
-
Carbone, M.A.1
-
7
-
-
33846219134
-
Unfolded protein response in a Drosophila model for retinal degeneration
-
Ryoo HD, Domingos PM, Kang MJ, Steller H (2007) Unfolded protein response in a Drosophila model for retinal degeneration. EMBO J 26(1):242-252.
-
(2007)
EMBO J
, vol.26
, Issue.1
, pp. 242-252
-
-
Ryoo, H.D.1
Domingos, P.M.2
Kang, M.J.3
Steller, H.4
-
8
-
-
84866426074
-
Wnt activation by wild type and mutant myocilin in cultured human trabecular meshwork cells
-
Shen X, Ying H, Yue BY (2012) Wnt activation by wild type and mutant myocilin in cultured human trabecular meshwork cells. PLoS One 7(9):e44902.
-
(2012)
PLoS One
, vol.7
, Issue.9
, pp. e44902
-
-
Shen, X.1
Ying, H.2
Yue, B.Y.3
-
9
-
-
64649096639
-
Myocilin is a modulator of Wnt signaling
-
Kwon HS, Lee HS, Ji Y, Rubin JS, Tomarev SI (2009) Myocilin is a modulator of Wnt signaling. Mol Cell Biol 29(8):2139-2154.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.8
, pp. 2139-2154
-
-
Kwon, H.S.1
Lee, H.S.2
Ji, Y.3
Rubin, J.S.4
Tomarev, S.I.5
-
10
-
-
65549150446
-
The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration
-
Kang KH, Lemke G, Kim JW (2009) The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration. Trends Mol Med 15(5):191-198.
-
(2009)
Trends Mol Med
, vol.15
, Issue.5
, pp. 191-198
-
-
Kang, K.H.1
Lemke, G.2
Kim, J.W.3
-
11
-
-
45549087104
-
Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: Protection by antioxidants
-
He Y, et al. (2008) Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: Protection by antioxidants. Invest Ophthalmol Vis Sci 49(4):1447-1458.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, Issue.4
, pp. 1447-1458
-
-
He, Y.1
-
12
-
-
67651087105
-
Mitochondrial dysfunction and glaucoma
-
Kong GY, Van Bergen NJ, Trounce IA, Crowston JG (2009) Mitochondrial dysfunction and glaucoma. J Glaucoma 18(2):93-100.
-
(2009)
J Glaucoma
, vol.18
, Issue.2
, pp. 93-100
-
-
Kong, G.Y.1
Van Bergen, N.J.2
Trounce, I.A.3
Crowston, J.G.4
-
13
-
-
62549099626
-
Pathogenesis of retinitis pigmentosa associated with apoptosis-inducing mutations in carbonic anhydrase IV
-
Datta R, Waheed A, Bonapace G, Shah GN, Sly WS (2009) Pathogenesis of retinitis pigmentosa associated with apoptosis-inducing mutations in carbonic anhydrase IV. Proc Natl Acad Sci USA 106(9):3437-3442.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.9
, pp. 3437-3442
-
-
Datta, R.1
Waheed, A.2
Bonapace, G.3
Shah, G.N.4
Sly, W.S.5
-
15
-
-
33750330814
-
Of flies and man: Drosophila as a model for human complex traits
-
Mackay TFC, Anholt R R H (2006) Of flies and man: Drosophila as a model for human complex traits. Annu Rev Genomics Hum Genet 7:339-367.
-
(2006)
Annu Rev Genomics Hum Genet
, vol.7
, pp. 339-367
-
-
Mackay, T.F.C.1
Anholt, R.R.H.2
-
16
-
-
58149380019
-
Drosophila models of Alzheimer's amyloidosis: The challenge of dissecting the complex mechanisms of toxicity of amyloid-beta 42
-
Iijima K, Iijima-Ando K (2008) Drosophila models of Alzheimer's amyloidosis: The challenge of dissecting the complex mechanisms of toxicity of amyloid-beta 42. J Alzheimers Dis 15(4):523-540.
-
(2008)
J Alzheimers Dis
, vol.15
, Issue.4
, pp. 523-540
-
-
Iijima, K.1
Iijima-Ando, K.2
-
17
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany MB, Bender WW (2000) A Drosophila model of Parkinson's disease. Nature 404(6776):394-398.
-
(2000)
Nature
, vol.404
, Issue.6776
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
18
-
-
1542267796
-
Cytoplasmic aggregates trap polyglutaminecontaining proteins and block axonal transport in a Drosophila model of Huntington's disease
-
Lee WC, Yoshihara M, Littleton JT (2004) Cytoplasmic aggregates trap polyglutaminecontaining proteins and block axonal transport in a Drosophila model of Huntington's disease. Proc Natl Acad Sci USA 101(9):3224-3229.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.9
, pp. 3224-3229
-
-
Lee, W.C.1
Yoshihara, M.2
Littleton, J.T.3
-
19
-
-
0043095549
-
Dopa decarboxylase (Ddc) affects variation in Drosophila longevity
-
De Luca M, et al. (2003) Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. Nat Genet 34(4):429-433.
-
(2003)
Nat Genet
, vol.34
, Issue.4
, pp. 429-433
-
-
De Luca, M.1
-
20
-
-
61349167072
-
Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep
-
Harbison ST, et al. (2009) Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. Nat Genet 41(3):371-375.
-
(2009)
Nat Genet
, vol.41
, Issue.3
, pp. 371-375
-
-
Harbison, S.T.1
-
21
-
-
0037117494
-
Fighting fruit flies: A model system for the study of aggression
-
Chen S, Lee AY, Bowens NM, Huber R, Kravitz EA (2002) Fighting fruit flies: A model system for the study of aggression. Proc Natl Acad Sci USA 99(8):5664-5668.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.8
, pp. 5664-5668
-
-
Chen, S.1
Lee, A.Y.2
Bowens, N.M.3
Huber, R.4
Kravitz, E.A.5
-
22
-
-
70349313058
-
Quantitative trait loci for aggressive behavior in Drosophila melanogaster
-
Edwards AC, Mackay T F C (2009) Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics 182(3):889-897.
-
(2009)
Genetics
, vol.182
, Issue.3
, pp. 889-897
-
-
Edwards, A.C.1
Mackay, T.F.C.2
-
24
-
-
84936851454
-
Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior
-
Shorter J, et al. (2015) Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior. Proc Natl Acad Sci USA 112(27):E3555-E3563.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, Issue.27
, pp. E3555-E3563
-
-
Shorter, J.1
-
25
-
-
84892762224
-
Alcohol-induced histone acetylation reveals a gene network involved in alcohol tolerance
-
Ghezzi A, et al. (2013) Alcohol-induced histone acetylation reveals a gene network involved in alcohol tolerance. PLoS Genet 9(12):e1003986.
-
(2013)
PLoS Genet
, vol.9
, Issue.12
, pp. e1003986
-
-
Ghezzi, A.1
-
26
-
-
84955510469
-
Mutations in the circadian gene period alter behavioral and biochemical responses to ethanol in Drosophila
-
Liao J, Seggio JA, Ahmad ST (2016) Mutations in the circadian gene period alter behavioral and biochemical responses to ethanol in Drosophila. Behav Brain Res 302:213-219.
-
(2016)
Behav Brain Res
, vol.302
, pp. 213-219
-
-
Liao, J.1
Seggio, J.A.2
Ahmad, S.T.3
-
27
-
-
42949142215
-
Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster
-
Morozova TV, Anholt RRH, Mackay T F C (2007) Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. Genome Biol 8(10):R231.
-
(2007)
Genome Biol
, vol.8
, Issue.10
, pp. R231
-
-
Morozova, T.V.1
Anholt, R.R.H.2
Mackay, T.F.C.3
-
28
-
-
70649107890
-
Alcohol sensitivity in Drosophila: Translational potential of systems genetics
-
1SI-12SI
-
Morozova TV, et al. (2009) Alcohol sensitivity in Drosophila: Translational potential of systems genetics. Genetics 183(2):733-745, 1SI-12SI.
-
(2009)
Genetics
, vol.183
, Issue.2
, pp. 733-745
-
-
Morozova, T.V.1
-
29
-
-
84945262773
-
Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila
-
Morozova TV, et al. (2015) Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila. BMC Genomics 16(1):865.
-
(2015)
BMC Genomics
, vol.16
, Issue.1
, pp. 865
-
-
Morozova, T.V.1
-
30
-
-
79955377403
-
Transcriptional networks for alcohol sensitivity in Drosophila melanogaster
-
Morozova TV, Mackay TFC, Anholt R R H (2011) Transcriptional networks for alcohol sensitivity in Drosophila melanogaster. Genetics 187(4):1193-1205.
-
(2011)
Genetics
, vol.187
, Issue.4
, pp. 1193-1205
-
-
Morozova, T.V.1
Mackay, T.F.C.2
Anholt, R.R.H.3
-
31
-
-
84904258306
-
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines
-
Huang W, et al. (2014) Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. Genome Res 24(7):1193-1208.
-
(2014)
Genome Res
, vol.24
, Issue.7
, pp. 1193-1208
-
-
Huang, W.1
-
32
-
-
84872591709
-
Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior
-
Swarup S, Huang W, Mackay TFC, Anholt R R H (2013) Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior. Proc Natl Acad Sci USA 110(3):1017-1022.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.3
, pp. 1017-1022
-
-
Swarup, S.1
Huang, W.2
Mackay, T.F.C.3
Anholt, R.R.H.4
-
33
-
-
84859309622
-
Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster
-
Weber AL, et al. (2012) Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. PLoS One 7(4):e34745.
-
(2012)
PLoS One
, vol.7
, Issue.4
, pp. e34745
-
-
Weber, A.L.1
-
34
-
-
80054719520
-
Complex genetic architecture of Drosophila aggressive behavior
-
Zwarts L, et al. (2011) Complex genetic architecture of Drosophila aggressive behavior. Proc Natl Acad Sci USA 108(41):17070-17075.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.41
, pp. 17070-17075
-
-
Zwarts, L.1
-
35
-
-
0034708480
-
The genome sequence of Drosophila melanogaster
-
Adams MD, et al. (2000) The genome sequence of Drosophila melanogaster. Science 287(5461):2185-2195.
-
(2000)
Science
, vol.287
, Issue.5461
, pp. 2185-2195
-
-
Adams, M.D.1
-
37
-
-
34447530305
-
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
-
Dietzl G, et al. (2007) A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 448(7150):151-156.
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 151-156
-
-
Dietzl, G.1
-
38
-
-
10744233572
-
Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome
-
Parks AL, et al. (2004) Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome. Nat Genet 36(3):288-292.
-
(2004)
Nat Genet
, vol.36
, Issue.3
, pp. 288-292
-
-
Parks, A.L.1
-
39
-
-
10744231523
-
A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac
-
Thibault ST, et al. (2004) A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac. Nat Genet 36(3):283-287.
-
(2004)
Nat Genet
, vol.36
, Issue.3
, pp. 283-287
-
-
Thibault, S.T.1
-
40
-
-
0000064419
-
Behavioral mutants of Drosophila isolated by countercurrent distribution
-
Benzer S (1967) Behavioral mutants of Drosophila isolated by countercurrent distribution. Proc Natl Acad Sci USA 58(3):1112-1119.
-
(1967)
Proc Natl Acad Sci USA
, vol.58
, Issue.3
, pp. 1112-1119
-
-
Benzer, S.1
-
41
-
-
0017749144
-
Phototactic and geotactic behavior of countercurrent defective mutants of Drosophila melanogaster
-
Markow TA, Merriam J (1977) Phototactic and geotactic behavior of countercurrent defective mutants of Drosophila melanogaster. Behav Genet 7(6):447-455.
-
(1977)
Behav Genet
, vol.7
, Issue.6
, pp. 447-455
-
-
Markow, T.A.1
Merriam, J.2
-
42
-
-
84883399244
-
The Drosophila visual system: From neural circuits to behavior
-
Zhu Y (2013) The Drosophila visual system: From neural circuits to behavior. Cell Adhes Migr 7(4):333-344.
-
(2013)
Cell Adhes Migr
, vol.7
, Issue.4
, pp. 333-344
-
-
Zhu, Y.1
-
43
-
-
23744502192
-
Functional senescence in Drosophila melanogaster
-
Grotewiel MS, Martin I, Bhandari P, Cook-Wiens E (2005) Functional senescence in Drosophila melanogaster. Ageing Res Rev 4(3):372-397.
-
(2005)
Ageing Res Rev
, vol.4
, Issue.3
, pp. 372-397
-
-
Grotewiel, M.S.1
Martin, I.2
Bhandari, P.3
Cook-Wiens, E.4
-
44
-
-
84908226062
-
Loss of Na (+)/K (+)-ATPase in Drosophila photoreceptors leads to blindness and age-dependent neurodegeneration
-
Luan Z, Reddig K, Li HS (2014) Loss of Na (+)/K (+)-ATPase in Drosophila photoreceptors leads to blindness and age-dependent neurodegeneration. Exp Neurol 261:791-801.
-
(2014)
Exp Neurol
, vol.261
, pp. 791-801
-
-
Luan, Z.1
Reddig, K.2
Li, H.S.3
-
45
-
-
33747387670
-
Differential decline in behavioral performance of Drosophila melanogaster with age
-
Simon AF, Liang DT, Krantz DE (2006) Differential decline in behavioral performance of Drosophila melanogaster with age. Mech Ageing Dev 127(7):647-651.
-
(2006)
Mech Ageing Dev
, vol.127
, Issue.7
, pp. 647-651
-
-
Simon, A.F.1
Liang, D.T.2
Krantz, D.E.3
-
46
-
-
84863012360
-
The drosophila melanogaster genetic reference panel
-
Mackay TFC, et al. (2012) The Drosophila melanogaster Genetic Reference Panel. Nature 482(7384):173-178.
-
(2012)
Nature
, vol.482
, Issue.7384
, pp. 173-178
-
-
Mackay, T.F.C.1
-
47
-
-
0002067304
-
Estimation of genetic variances
-
eds Hanson WD, Robinson HF National Academy of Sciences-National Research Council, Washington, DC
-
Cockerham CC (1963) Estimation of genetic variances. Statistical Genetics and Plant Breeding, eds Hanson WD, Robinson HF (National Academy of Sciences-National Research Council, Washington, DC), pp 53-94.
-
(1963)
Statistical Genetics and Plant Breeding
, pp. 53-94
-
-
Cockerham, C.C.1
-
48
-
-
37249014088
-
Quantitative genomics of locomotor behavior in Drosophila melanogaster
-
Jordan KW, Carbone MA, Yamamoto A, Morgan TJ, Mackay TF (2007) Quantitative genomics of locomotor behavior in Drosophila melanogaster. Genome Biol 8(8):R172.
-
(2007)
Genome Biol
, vol.8
, Issue.8
, pp. R172
-
-
Jordan, K.W.1
Carbone, M.A.2
Yamamoto, A.3
Morgan, T.J.4
Mackay, T.F.5
-
49
-
-
84929405559
-
The genetic basis for variation in olfactory behavior in Drosophila melanogaster
-
Arya GH, et al. (2015) The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Chem Senses 40(4):233-243.
-
(2015)
Chem Senses
, vol.40
, Issue.4
, pp. 233-243
-
-
Arya, G.H.1
-
50
-
-
84959432052
-
Longevity GWAS using the Drosophila Genetic Reference Panel
-
Ivanov DK, et al. (2015) Longevity GWAS using the Drosophila Genetic Reference Panel. J Gerontol A Biol Sci Med Sci 70(12):1470-1478.
-
(2015)
J Gerontol A Biol Sci Med Sci
, vol.70
, Issue.12
, pp. 1470-1478
-
-
Ivanov, D.K.1
-
51
-
-
84866848293
-
Epistasis dominates the genetic architecture of Drosophila quantitative traits
-
Huang W, et al. (2012) Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci USA 109(39):15553-15559.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.39
, pp. 15553-15559
-
-
Huang, W.1
-
52
-
-
84966559388
-
FlyBase: Establishing a gene group resource for drosophila melanogaster
-
Attrill H, et al.; FlyBase Consortium (2016) FlyBase: Establishing a Gene Group resource for Drosophila melanogaster. Nucleic Acids Res 44(D1):D786-D792.
-
(2016)
Nucleic Acids Res
, vol.44
, Issue.D1
, pp. D786-D792
-
-
FlyBase Consortium1
Attrill, H.2
-
53
-
-
84906451949
-
Insulin sensitivity in longliving Ames dwarf mice
-
Wiesenborn DS, Ayala JE, King E, Masternak MM (2014) Insulin sensitivity in longliving Ames dwarf mice. Age (Dordr) 36(5):9709.
-
(2014)
Age (Dordr)
, vol.36
, Issue.5
, pp. 9709
-
-
Wiesenborn, D.S.1
Ayala, J.E.2
King, E.3
Masternak, M.M.4
-
54
-
-
40449142493
-
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
-
Selman C, et al. (2008) Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB J 22(3):807-818.
-
(2008)
FASEB J
, vol.22
, Issue.3
, pp. 807-818
-
-
Selman, C.1
-
55
-
-
0035815414
-
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
-
Clancy DJ, et al. (2001) Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292(5514):104-106.
-
(2001)
Science
, vol.292
, Issue.5514
, pp. 104-106
-
-
Clancy, D.J.1
-
56
-
-
3142749712
-
Long-lived Drosophila with overexpressed dFOXO in adult fat body
-
Giannakou ME, et al. (2004) Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science 305(5682):361.
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 361
-
-
Giannakou, M.E.1
-
57
-
-
2942563805
-
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
-
Hwangbo DS, Gershman B, Tu MP, Palmer M, Tatar M (2004) Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 429(6991):562-566.
-
(2004)
Nature
, vol.429
, Issue.6991
, pp. 562-566
-
-
Hwangbo, D.S.1
Gershman, B.2
Tu, M.P.3
Palmer, M.4
Tatar, M.5
-
58
-
-
84937191405
-
Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan
-
Bansal A, et al. (2014) Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan. Longev Healthspan 3:5.
-
(2014)
Longev Healthspan
, vol.3
, pp. 5
-
-
Bansal, A.1
-
59
-
-
84901741224
-
DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans
-
Tullet JM, et al. (2014) DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans. PLoS Genet 10(2):e1004109.
-
(2014)
PLoS Genet
, vol.10
, Issue.2
, pp. e1004109
-
-
Tullet, J.M.1
-
60
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein M, McVey M, Guarente L (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13(19):2570-2580.
-
(1999)
Genes Dev
, vol.13
, Issue.19
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
61
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin SJ, Defossez PA, Guarente L (2000) Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289(5487):2126-2128.
-
(2000)
Science
, vol.289
, Issue.5487
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
62
-
-
84916878091
-
A versatile two-step CRISPR- and RMCEbased strategy for efficient genome engineering in Drosophila
-
Zhang X, Koolhaas WH, Schnorrer F (2014) A versatile two-step CRISPR- and RMCEbased strategy for efficient genome engineering in Drosophila. G3(Bethesda) 4(12):2409-2418.
-
(2014)
G3 (Bethesda)
, vol.4
, Issue.12
, pp. 2409-2418
-
-
Zhang, X.1
Koolhaas, W.H.2
Schnorrer, F.3
-
63
-
-
84883809403
-
Highly efficient genome modifications mediated by CRISPR/Cas9 in Drosophila
-
Yu Z, et al. (2013) Highly efficient genome modifications mediated by CRISPR/Cas9 in Drosophila. Genetics 195(1):289-291.
-
(2013)
Genetics
, vol.195
, Issue.1
, pp. 289-291
-
-
Yu, Z.1
-
64
-
-
77956871485
-
Dorsal eye selector pannier (pnr) suppresses the eye fate to define dorsal margin of the Drosophila eye
-
Oros SM, Tare M, Kango-Singh M, Singh A (2010) Dorsal eye selector pannier (pnr) suppresses the eye fate to define dorsal margin of the Drosophila eye. Dev Biol 346(2):258-271.
-
(2010)
Dev Biol
, vol.346
, Issue.2
, pp. 258-271
-
-
Oros, S.M.1
Tare, M.2
Kango-Singh, M.3
Singh, A.4
-
65
-
-
0030913352
-
Immunolocalization of Drosophila eye-specific diacylgylcerol kinase, rdgA, which is essential for the maintenance of the photoreceptor
-
Masai I, Suzuki E, Yoon CS, Kohyama A, Hotta Y (1997) Immunolocalization of Drosophila eye-specific diacylgylcerol kinase, rdgA, which is essential for the maintenance of the photoreceptor. J Neurobiol 32(7):695-706.
-
(1997)
J Neurobiol
, vol.32
, Issue.7
, pp. 695-706
-
-
Masai, I.1
Suzuki, E.2
Yoon, C.S.3
Kohyama, A.4
Hotta, Y.5
-
66
-
-
23844490723
-
TRP channels in Drosophila photoreceptor cells
-
Montell C (2005) TRP channels in Drosophila photoreceptor cells. J Physiol 567(Pt 1):45-51.
-
(2005)
J Physiol
, vol.567
, pp. 45-51
-
-
Montell, C.1
-
67
-
-
26444447466
-
Light-regulated interaction of Dmoesin with TRP and TRPL channels is required for maintenance of photoreceptors
-
Chorna-Ornan I, et al. (2005) Light-regulated interaction of Dmoesin with TRP and TRPL channels is required for maintenance of photoreceptors. J Cell Biol 171(1):143-152.
-
(2005)
J Cell Biol
, vol.171
, Issue.1
, pp. 143-152
-
-
Chorna-Ornan, I.1
-
68
-
-
84903973976
-
Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits
-
Durham MF, Magwire MM, Stone EA, Leips J (2014) Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Nat Commun 5:4338.
-
(2014)
Nat Commun
, vol.5
, pp. 4338
-
-
Durham, M.F.1
Magwire, M.M.2
Stone, E.A.3
Leips, J.4
-
69
-
-
84863875322
-
Age-specific variation in immune response in Drosophila melanogaster has a genetic basis
-
Felix TM, Hughes KA, Stone EA, Drnevich JM, Leips J (2012) Age-specific variation in immune response in Drosophila melanogaster has a genetic basis. Genetics 191(3):989-1002.
-
(2012)
Genetics
, vol.191
, Issue.3
, pp. 989-1002
-
-
Felix, T.M.1
Hughes, K.A.2
Stone, E.A.3
Drnevich, J.M.4
Leips, J.5
-
70
-
-
0029744895
-
Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins
-
Schnepp B, Grumbling G, Donaldson T, Simcox A (1996) Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins. Genes Dev 10(18):2302-2313.
-
(1996)
Genes Dev
, vol.10
, Issue.18
, pp. 2302-2313
-
-
Schnepp, B.1
Grumbling, G.2
Donaldson, T.3
Simcox, A.4
-
71
-
-
0141632951
-
Reciprocal interactions between neurons and glia are required for Drosophila peripheral nervous system development
-
Sepp KJ, Auld VJ (2003) Reciprocal interactions between neurons and glia are required for Drosophila peripheral nervous system development. J Neurosci 23(23):8221-8230.
-
(2003)
J Neurosci
, vol.23
, Issue.23
, pp. 8221-8230
-
-
Sepp, K.J.1
Auld, V.J.2
-
72
-
-
0037452947
-
A function for Egf receptor signaling in expanding the developing brain in Drosophila
-
Page DT (2003) A function for Egf receptor signaling in expanding the developing brain in Drosophila. Curr Biol 13(6):474-482.
-
(2003)
Curr Biol
, vol.13
, Issue.6
, pp. 474-482
-
-
Page, D.T.1
-
73
-
-
84872105148
-
Drosophila king tubby (ktub) mediates light-induced rhodopsin endocytosis and retinal degeneration
-
Chen SF, Tsai YC, Fan SS (2012) Drosophila king tubby (ktub) mediates light-induced rhodopsin endocytosis and retinal degeneration. J Biomed Sci 19:101.
-
(2012)
J Biomed Sci
, vol.19
, pp. 101
-
-
Chen, S.F.1
Tsai, Y.C.2
Fan, S.S.3
-
74
-
-
33646889804
-
Domain-specific early and late function of Dpatj in Drosophila photoreceptor cells
-
Nam SC, Choi KW (2006) Domain-specific early and late function of Dpatj in Drosophila photoreceptor cells. Dev Dyn 235(6):1501-1507.
-
(2006)
Dev Dyn
, vol.235
, Issue.6
, pp. 1501-1507
-
-
Nam, S.C.1
Choi, K.W.2
-
75
-
-
84888156818
-
Antagonistic feedback loops involving Rau and Sprouty in the Drosophila eye control neuronal and glial differentiation
-
Sieglitz F, et al. (2013) Antagonistic feedback loops involving Rau and Sprouty in the Drosophila eye control neuronal and glial differentiation. Sci Signal 6(300):ra96.
-
(2013)
Sci Signal
, vol.6
, Issue.300
, pp. ra96
-
-
Sieglitz, F.1
-
76
-
-
33846138014
-
Sprinter: A novel transmembrane protein required for Wg secretion and signaling
-
Goodman RM, et al. (2006) Sprinter: A novel transmembrane protein required for Wg secretion and signaling. Development 133(24):4901-4911.
-
(2006)
Development
, vol.133
, Issue.24
, pp. 4901-4911
-
-
Goodman, R.M.1
-
77
-
-
33646123992
-
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
-
Bartscherer K, Pelte N, Ingelfinger D, Boutros M (2006) Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125(3):523-533.
-
(2006)
Cell
, vol.125
, Issue.3
, pp. 523-533
-
-
Bartscherer, K.1
Pelte, N.2
Ingelfinger, D.3
Boutros, M.4
-
78
-
-
17744371655
-
A summary of 20 CACNA1F mutations identified in 36 families with incomplete X-linked congenital stationary night blindness, and characterization of splice variants
-
Boycott KM, et al. (2001) A summary of 20 CACNA1F mutations identified in 36 families with incomplete X-linked congenital stationary night blindness, and characterization of splice variants. Hum Genet 108(2):91-97.
-
(2001)
Hum Genet
, vol.108
, Issue.2
, pp. 91-97
-
-
Boycott, K.M.1
-
79
-
-
0026089211
-
Localization of the Aland Island eye disease locus to the pericentromeric region of the X chromosome by linkage analysis
-
Alitalo T, Kruse TA, Forsius H, Eriksson AW, de la Chapelle A (1991) Localization of the Aland Island eye disease locus to the pericentromeric region of the X chromosome by linkage analysis. Am J Hum Genet 48(1):31-38.
-
(1991)
Am J Hum Genet
, vol.48
, Issue.1
, pp. 31-38
-
-
Alitalo, T.1
Kruse, T.A.2
Forsius, H.3
Eriksson, A.W.4
De La Chapelle, A.5
-
80
-
-
0027482799
-
Genetic mapping of a cone and rod dysfunction (Aland Island eye disease) to the proximal short arm of the human X chromosome
-
Glass IA, et al. (1993) Genetic mapping of a cone and rod dysfunction (Aland Island eye disease) to the proximal short arm of the human X chromosome. J Med Genet 30(12):1044-1050.
-
(1993)
J Med Genet
, vol.30
, Issue.12
, pp. 1044-1050
-
-
Glass, I.A.1
-
81
-
-
33747047272
-
X linked cone-rod dystrophy, CORDX3, is caused by a mutation in the CACNA1F gene
-
Jalkanen R, et al. (2006) X linked cone-rod dystrophy, CORDX3, is caused by a mutation in the CACNA1F gene. J Med Genet 43(8):699-704.
-
(2006)
J Med Genet
, vol.43
, Issue.8
, pp. 699-704
-
-
Jalkanen, R.1
-
82
-
-
84895192951
-
WNT/Frizzled signalling: Receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3
-
Dijksterhuis JP, Petersen J, Schulte G (2014) WNT/Frizzled signalling: Receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3. Br J Pharmacol 171(5):1195-1209.
-
(2014)
Br J Pharmacol
, vol.171
, Issue.5
, pp. 1195-1209
-
-
Dijksterhuis, J.P.1
Petersen, J.2
Schulte, G.3
-
83
-
-
84901920432
-
Identification of the cellular mechanisms that modulate trafficking of frizzled family receptor 4 (FZD4) missense mutants associated with familial exudative vitreoretinopathy
-
Milhem RM, Ben-Salem S, Al-Gazali L, Ali BR (2014) Identification of the cellular mechanisms that modulate trafficking of frizzled family receptor 4(FZD4) missense mutants associated with familial exudative vitreoretinopathy. Invest Ophthalmol Vis Sci 55(6):3423-3431.
-
(2014)
Invest Ophthalmol Vis Sci
, vol.55
, Issue.6
, pp. 3423-3431
-
-
Milhem, R.M.1
Ben-Salem, S.2
Al-Gazali, L.3
Ali, B.R.4
-
84
-
-
0032231607
-
Congenital fibrosis of the extraocular muscles type 2, an inherited exotropic strabismus fixus, maps to distal 11q13
-
Wang SM, et al. (1998) Congenital fibrosis of the extraocular muscles type 2, an inherited exotropic strabismus fixus, maps to distal 11q13. Am J Hum Genet 63(2):517-525.
-
(1998)
Am J Hum Genet
, vol.63
, Issue.2
, pp. 517-525
-
-
Wang, S.M.1
-
85
-
-
0035179560
-
Homozygous mutations in ARIX (PHOX2A) result in congenital fibrosis of the extraocular muscles type 2
-
Nakano M, et al. (2001) Homozygous mutations in ARIX (PHOX2A) result in congenital fibrosis of the extraocular muscles type 2. Nat Genet 29(3):315-320.
-
(2001)
Nat Genet
, vol.29
, Issue.3
, pp. 315-320
-
-
Nakano, M.1
-
86
-
-
17144456542
-
TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa
-
Banerjee P, et al. (1998) TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa. Nat Genet 18(2):177-179.
-
(1998)
Nat Genet
, vol.18
, Issue.2
, pp. 177-179
-
-
Banerjee, P.1
-
87
-
-
34447502521
-
Novel compound heterozygous TULP1 mutations in a family with severe early-onset retinitis pigmentosa
-
den Hollander AI, et al. (2007) Novel compound heterozygous TULP1 mutations in a family with severe early-onset retinitis pigmentosa. Arch Ophthalmol 125(7):932-935.
-
(2007)
Arch Ophthalmol
, vol.125
, Issue.7
, pp. 932-935
-
-
Den Hollander, A.I.1
-
88
-
-
38549134461
-
Identification of novel mutations in patients with Leber congenital amaurosis and juvenile RP by genome-wide homozygosity mapping with SNP microarrays
-
den Hollander AI, et al. (2007) Identification of novel mutations in patients with Leber congenital amaurosis and juvenile RP by genome-wide homozygosity mapping with SNP microarrays. Invest Ophthalmol Vis Sci 48(12):5690-5698.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, Issue.12
, pp. 5690-5698
-
-
Den Hollander, A.I.1
-
89
-
-
38449104764
-
Novel TULP1 mutation causing leber congenital amaurosis or early onset retinal degeneration
-
Mataftsi A, et al. (2007) Novel TULP1 mutation causing leber congenital amaurosis or early onset retinal degeneration. Invest Ophthalmol Vis Sci 48(11):5160-5167.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, Issue.11
, pp. 5160-5167
-
-
Mataftsi, A.1
-
90
-
-
79957589306
-
Recessive LAMC3 mutations cause malformations of occipital cortical development
-
Barak T, et al. (2011) Recessive LAMC3 mutations cause malformations of occipital cortical development. Nat Genet 43(6):590-594.
-
(2011)
Nat Genet
, vol.43
, Issue.6
, pp. 590-594
-
-
Barak, T.1
-
91
-
-
84932100280
-
The myosin chaperone UNC45B is involved in lens development and autosomal dominant juvenile cataract
-
Hansen L, et al. (2014) The myosin chaperone UNC45B is involved in lens development and autosomal dominant juvenile cataract. Eur J Hum Genet 22(11):1290-1297.
-
(2014)
Eur J Hum Genet
, vol.22
, Issue.11
, pp. 1290-1297
-
-
Hansen, L.1
-
92
-
-
19944416896
-
VSX1 mutational analysis in a series of Italian patients affected by keratoconus: Detection of a novel mutation
-
Bisceglia L, et al. (2005) VSX1 mutational analysis in a series of Italian patients affected by keratoconus: Detection of a novel mutation. Invest Ophthalmol Vis Sci 46(1):39-45.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, Issue.1
, pp. 39-45
-
-
Bisceglia, L.1
-
93
-
-
77953556702
-
Mutational screening of VSX1 in keratoconus patients from the European population
-
Dash DP, et al. (2010) Mutational screening of VSX1 in keratoconus patients from the European population. Eye (Lond) 24(6):1085-1092.
-
(2010)
Eye (Lond)
, vol.24
, Issue.6
, pp. 1085-1092
-
-
Dash, D.P.1
-
94
-
-
0036566556
-
VSX1: A gene for posterior polymorphous dystrophy and keratoconus
-
Héon E, et al. (2002) VSX1: A gene for posterior polymorphous dystrophy and keratoconus. Hum Mol Genet 11(9):1029-1036.
-
(2002)
Hum Mol Genet
, vol.11
, Issue.9
, pp. 1029-1036
-
-
Héon, E.1
-
95
-
-
4544279121
-
CHX10 mutations cause non-syndromic microphthalmia/anophthalmia in Arab and Jewish kindreds
-
Bar-Yosef U, et al. (2004) CHX10 mutations cause non-syndromic microphthalmia/anophthalmia in Arab and Jewish kindreds. Hum Genet 115(4):302-309.
-
(2004)
Hum Genet
, vol.115
, Issue.4
, pp. 302-309
-
-
Bar-Yosef, U.1
-
96
-
-
34547862116
-
Mutations in the CHX10 gene in non-syndromic microphthalmia/anophthalmia patients from Qatar
-
Faiyaz-Ul-Haque M, et al. (2007) Mutations in the CHX10 gene in non-syndromic microphthalmia/anophthalmia patients from Qatar. Clin Genet 72(2):164-166.
-
(2007)
Clin Genet
, vol.72
, Issue.2
, pp. 164-166
-
-
Faiyaz-Ul-Haque, M.1
-
97
-
-
77949587649
-
Fast and accurate long-read alignment with Burrows-Wheeler transform
-
Li H, Durbin R (2010) Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 26(5):589-595.
-
(2010)
Bioinformatics
, vol.26
, Issue.5
, pp. 589-595
-
-
Li, H.1
Durbin, R.2
-
98
-
-
79955483667
-
A framework for variation discovery and genotyping using next-generation DNA sequencing data
-
DePristo MA, et al. (2011) A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet 43(5):491-498.
-
(2011)
Nat Genet
, vol.43
, Issue.5
, pp. 491-498
-
-
DePristo, M.A.1
-
100
-
-
60849114746
-
KEGG spider: Interpretation of genomics data in the context of the global gene metabolic network
-
Antonov AV, Dietmann S, Mewes HW (2008) KEGG spider: Interpretation of genomics data in the context of the global gene metabolic network. Genome Biol 9(12):R179.
-
(2008)
Genome Biol
, vol.9
, Issue.12
, pp. R179
-
-
Antonov, A.V.1
Dietmann, S.2
Mewes, H.W.3
-
101
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4(1):44-57.
-
(2009)
Nat Protoc
, vol.4
, Issue.1
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
102
-
-
58549112996
-
Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
-
Huang W, Sherman BT, Lempicki RA (2009) Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37(1):1-13.
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.1
, pp. 1-13
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
|