Light-regulated interaction of Dmoesin with TRP and TRPL channels is required for maintenance of photoreceptors

Journal of Cell Biology

Volumn 171, Issue 1, 2005, Pages 143-152

  Chorna Ornan, Irit ^a   Tzarfaty, Vered ^a   Ankri Eliahoo, Galit ^a   Joel Almagor, Tamar ^a   Meyer, Nina E ^b   Huber, Armin ^b   Payre, François ^c   Minke, Baruch ^a  

^a HEBREW UNIVERSITY   (Israel)

^b UNIVERSITY OF KARLSRUHE   (Germany)

^c Centre de Biologie du Developpement Toulouse   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; DMOESIN; DROSOPHILA PROTEIN; EZRIN; INSECT PROTEIN; ISOPROTEIN; MOESIN; MUTANT PROTEIN; RADIXIN; THREONINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DARKNESS; DISSOCIATION; DROSOPHILA MELANOGASTER; FLY; ILLUMINATION; LIGHT; MEMBRANE; MOLECULAR INTERACTION; NONHUMAN; PATHOGENESIS; PHOTOACTIVATION; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REGULATORY MECHANISM; RETINA DEGENERATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL MEMBRANE; CYTOSOL; DROSOPHILA PROTEINS; LIGHT; MEMBRANE PROTEINS; MODELS, MOLECULAR; MUTATION; PHOSPHORYLATION; PHOTORECEPTORS, INVERTEBRATE; PROTEIN TRANSPORT; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

DROSOPHILA MELANOGASTER;

EID: 26444447466     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200503014     Document Type: Article

References (39)

1. Bähner, M., S. Frechter, N. Da Silva, B. Minke, R. Paulsen, and A. Huber. 2002. Light-regulated subcellular translocation of Drosophila TRPL channels induces long-term adaptation and modifies the light-induced current. Neuron. 34:83-93.
2. 2-terminal domain of ezrin correlates with its altered cellular distribution. J. Cell Biol. 151:1067-1080.
3. Brand, A.H., and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118:401-415.
4. Bretscher, A., K. Edwards, and R.G. Fehon. 2002. ERM proteins and merlin: integrators at the cell cortex. Nat. Rev. Mol. Cell Biol. 3:586-599.
5. Chou, W.H., K.J. Hall, D.B. Wilson, C.L. Wideman, S.M. Townson, L.V. Chadwell, and S.G. Britt. 1996. Identification of a novel Drosophila opsin reveals specific patterning of the R7 and R8 photoreceptor cells. Neuron. 17:1101-1115.
6. Chevesich, J., A.J. Kreuz, and C. Montell. 1997. Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex. Neuron. 18:95-105.
7. Fievet, B.T., A. Gautreau, C. Roy, L. Del Maestro, P. Mangeat, D. Louvard, and M. Arpin. 2004. Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin. J. Cell Biol. 164:653-659.
8. 2+ channel in Drosophila photoreceptors. Neuron. 8:643-651.
9. 2+ and trp. Cell Calcium. 18:256-274.
10. Hirao, M., N. Sato, T. Kondo, S. Yonemura, M. Monden, T. Sasaki, Y. Takai, and S. Tsukita. 1996. Regulation mechanism of ERM (ezrin/radixin/ moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J. Cell Biol. 135:37-51.
11. 2+ channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC and InaD. EMBO J. 15:7036-7045.
12. Jankovics, F., R. Sinka, T. Lukacsovich, and M. Erdelyi. 2002. MOESIN crosslinks actin and cell membrane in Drosophila oocytes and is required for OSKAR anchoring. Curr. Biol. 12:2060-2065.
13. Karagiosis, S.A., and D.F. Ready. 2004. Moesin contributes an essential structural role in Drosophila photoreceptor morphogenesis. Development. 131:725-732.
14. Kirschfeld, K., and N. Franceschini. 1977. Photostable pigments within the membrane of photoreceptors and their possible role. Biophys. Struct. Mech. 3:191-194.
15. Kosloff, M., N. Elia, T. Joel-Almagor, R. Timberg, T.D. Zars, D.R. Hyde, B. Minke, and Z. Selinger. 2003. Regulation of light-dependent Gqalpha translocation and morphological changes in fly photoreceptors. EMBO J. 22:459-468.
16. 2+ influx without disruption of Trp3-inositol trisphosphate receptor association. J. Biol. Chem. 276:42401-42408.
17. Mery, L., B. Strauss, J.F. Dufour, K.H. Krause, and M. Hoth. 2002. The PDZ-interacting domain of TRPC4 controls its localization and surface expression in HEK293 cells. J. Cell Sci. 115:3497-3508.
18. Minke, B., and K. Agam. 2003. TRP gating is linked to the metabolic state and maintenance of the Drosophila photoreceptor cells. Cell Calcium. 33:395-408.
19. Montell, C. 1998. TRP trapped in fly signaling web. Curr. Opin. Neurobiol. 8:389-397.
20. Niemeyer, B.A., E. Suzuki, K. Scott, K. Jalink, and C.S. Zuker. 1996. The Drosophila light-activated conductance is composed of the two channels TRP and TRPL. Cell. 85:651-659.
21. Niggli, V., C. Andreoli, C. Roy, and P. Mangeat. 1995. Identification of a phosphatidylinositol-4,5-bisphosphate-binding domain in the N-terminal region of ezrin. FEBS Lett. 376:172-176.
22. Obukhov, A.G., and M.C. Nowycky. 2004. TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/radixin/moesin-binding phosphoprotein-50 (EBP50). J. Cell. Physiol. 201:227-235.
23. Pearn, M.T., L.L. Randall, R.D. Shortridge, M.G. Burg, and W.L. Pak. 1996. Molecular, biochemical, and electrophysiological characterization of Drosophila norpA mutants. J. Biol. Chem. 271:4937-4945.
24. 2+ influx into Drosophila photoreceptors. J. Gen. Physiol. 104:1057-1077.
25. Peretz, A., E. Suss-Toby, A. Rom-Glas, A. Arnon, R. Payne, and B. Minke. 1994b. The light response of Drosophila photoreceptors is accompanied by an increase in cellular calcium: effects of specific mutations. Neuron. 12:1257-1267.
26. Phillips, A.M., A. Bull, and L.E. Kelly. 1992. Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene. Neuron. 8:631-642.
27. Polesello, C., and F. Payre. 2004. Small is beautiful: what flies tell us about ERM protein function in development. Trends Cell Biol. 14:294-302.
28. Polesello, C., I. Delon, P. Valenti, P. Ferrer, and F. Payre. 2002. Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis. Nat. Cell Biol. 4:782-789.
29. 2+ influx is localized adjacent to the calcium stores in Drosophila photoreceptors. J. Neurosci. 15:3747-3760.
30. Ready, D.F., T.E. Hanson, and S. Benzer. 1976. Development of the Drosophila retina, a neurocrystalline lattice. Dev. Biol. 53:217-240.
31. Rubinstein, C.T., S. Bar-Nachum, Z. Selinger, and B. Minke. 1989. Chemically induced retinal degeneration in the rdgB (retinal degeneration B) mutant of Drosophila. Vis. Neurosci. 2:541-551.
32. Scott, K., Y. Sun, K. Beckingham, and C.S. Zuker. 1997. Calmodulin regulation of Drosophila light-activated channels and receptor function mediates termination of the light response in vivo. Cell. 91:375-383.
33. 2+ channel by INAD in Drosophila photoreceptors. Neuron. 16:991-998.
34. Shieh, B.H., M.Y. Zhu, J.K. Lee, I.M. Kelly, and F. Bahiraei. 1997. Association of INAD with NORPA is essential for controlled activation and deactivation of Drosophila phototransduction in vivo. Proc. Natl. Acad. Sci. USA. 94:12682-12687.
35. Speck, O., S.C. Hughes, N.K. Noren, R.M. Kulikauskas, and R.G. Fehon. 2003. Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity. Nature. 421:83-87.
36. Tang, Y., J. Tang, Z. Chen, C. Trost, V. Flockerzi, M. Li, V. Ramesh, and M.X. Zhu. 2000. Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF. J. Biol. Chem. 275:37559-37564.
37. Tsukita, S., and G. Matsumoto. 1988. Light-induced structural changes of cytoskeleton in squid photoreceptor microvilli detected by rapid-freeze method. J. Cell Biol. 106:1151-1160.
38. Tsunoda, S., J. Sierralta, Y. Sun, R. Bodner, E. Suzuki, A. Becker, M. Socolich, and C.S. Zuker. 1997. A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade. Nature. 388:243-249.
39. Van Vactor, D., Jr., D.E. Krantz, R. Reinke, and S.L. Zipursky. 1988. Analysis of mutants in chaoptin, a photoreceptor cell-specific glycoprotein in Drosophila, reveals its role in cellular morphogenesis. Cell. 52:281-290.