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Volumn 10, Issue , 2015, Pages 547-562

Genetics and epigenetics of human retinoblastoma

Author keywords

epigenetics; genetics; RB1; retinoblastoma

Indexed keywords

KIF14 PROTEIN; MICRORNA; PROTEIN; PROTEIN MDMX; UNCLASSIFIED DRUG; UVOMORULIN; RETINOBLASTOMA PROTEIN;

EID: 84921930606     PISSN: 15534006     EISSN: 15534014     Source Type: Book Series    
DOI: 10.1146/annurev-pathol-012414-040259     Document Type: Article
Times cited : (121)

References (100)
  • 1
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson Jr. AG. 1971. Mutation and cancer: statistical study of retinoblastoma. PNAS 68:820-23
    • (1971) PNAS , vol.68 , pp. 820-823
    • Knudson, A.G.1
  • 2
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, et al. 1986. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323:643-46
    • (1986) Nature , vol.323 , pp. 643-646
    • Friend, S.H.1    Bernards, R.2    Rogelj, S.3    Weinberg, R.A.4    Rapaport, J.M.5
  • 3
    • 0023767249 scopus 로고
    • Identification of germline and somatic mutations affecting the retinoblastoma gene
    • Dunn JM, Phillips RA, Becker AJ, Gallie BL. 1988. Identification of germline and somatic mutations affecting the retinoblastoma gene. Science 241:1797-800
    • (1988) Science , vol.241 , pp. 1797-1800
    • Dunn, J.M.1    Phillips, R.A.2    Becker, A.J.3    Gallie, B.L.4
  • 4
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. 2011. Hallmarks of cancer: the next generation. Cell 144:646-74
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 5
    • 77954522274 scopus 로고    scopus 로고
    • Loss of pRB causes centromere dysfunction and chromosomal instability
    • Manning AL, Longworth MS, Dyson NJ. 2010. Loss of pRB causes centromere dysfunction and chromosomal instability. Genes Dev. 24:1364-76
    • (2010) Genes Dev. , vol.24 , pp. 1364-1376
    • Manning, A.L.1    Longworth, M.S.2    Dyson, N.J.3
  • 6
    • 4043093341 scopus 로고    scopus 로고
    • Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
    • Hernando E, Nahle Z, Juan G, Diaz-Rodriguez E, Alaminos M, et al. 2004. Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature 430:797-802
    • (2004) Nature , vol.430 , pp. 797-802
    • Hernando, E.1    Nahle, Z.2    Juan, G.3    Diaz-Rodriguez, E.4    Alaminos, M.5
  • 7
    • 43049139917 scopus 로고    scopus 로고
    • Loss of RB1 induces nonproliferative retinoma: Increasing genomic instability correlates with progression to retinoblastoma
    • Dimaras H, Khetan V, Halliday W, Orlic M, Prigoda NL, et al. 2008. Loss of RB1 induces nonproliferative retinoma: Increasing genomic instability correlates with progression to retinoblastoma. Hum. Mol. Genet. 17:1363-72
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 1363-1372
    • Dimaras, H.1    Khetan, V.2    Halliday, W.3    Orlic, M.4    Prigoda, N.L.5
  • 8
    • 70749128701 scopus 로고    scopus 로고
    • RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation
    • Amato A, Lentini L, Schillaci T, Iovino F, Di Leonardo A. 2009. RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation. BMC Cell Biol. 10:79
    • (2009) BMC Cell Biol. , vol.10 , pp. 79
    • Amato, A.1    Lentini, L.2    Schillaci, T.3    Iovino, F.4    Di Leonardo, A.5
  • 9
    • 33750220492 scopus 로고    scopus 로고
    • RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
    • Iovino F, Lentini L, Amato A, Di Leonardo A. 2006. RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts. Mol. Cancer 5:38
    • (2006) Mol. Cancer , vol.5 , pp. 38
    • Iovino, F.1    Lentini, L.2    Amato, A.3    Di Leonardo, A.4
  • 11
    • 84862777113 scopus 로고    scopus 로고
    • A novel retinoblastoma therapy from genomic and epigenetic analyses
    • Zhang J, Benavente CA, McEvoy J, Flores-Otero J, Ding L, et al. 2012. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature 481:329-34
    • (2012) Nature , vol.481 , pp. 329-334
    • Zhang, J.1    Benavente, C.A.2    McEvoy, J.3    Flores-Otero, J.4    Ding, L.5
  • 12
    • 19444377455 scopus 로고    scopus 로고
    • Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization
    • Zielinski B, Gratias S, Toedt G, Mendrzyk F, Stange DE, et al. 2005. Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization. Genes Chromosomes Cancer 43:294-301
    • (2005) Genes Chromosomes Cancer , vol.43 , pp. 294-301
    • Zielinski, B.1    Gratias, S.2    Toedt, G.3    Mendrzyk, F.4    Stange, D.E.5
  • 13
    • 0033963984 scopus 로고    scopus 로고
    • Engraftment and growth of patient-derived retinoblastoma tumour in severe combined immunodeficiency mice
    • Yan Y, Dunkel IJ, Guan X, Abramson DH, Jhanwar SC, O'Reilly RJ. 2000. Engraftment and growth of patient-derived retinoblastoma tumour in severe combined immunodeficiency mice. Eur. J. Cancer 36:221-28
    • (2000) Eur. J. Cancer , vol.36 , pp. 221-228
    • Yan, Y.1    Dunkel, I.J.2    Guan, X.3    Abramson, D.H.4    Jhanwar, S.C.5    O'Reilly, R.J.6
  • 15
    • 0022401270 scopus 로고
    • A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma
    • Squire J, Gallie BL, Phillips RA. 1985. A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma. Hum. Genet. 70:291-301
    • (1985) Hum. Genet. , vol.70 , pp. 291-301
    • Squire, J.1    Gallie, B.L.2    Phillips, R.A.3
  • 16
    • 0021324866 scopus 로고
    • Isochromosome 6p, a unique chromosomal abnormality in retinoblastoma: Verification by standard staining techniques, new densitometric methods, and somatic cell hybridization
    • Squire J, Phillips RA, Boyce S, Godbout R, Rogers B, Gallie BL. 1984. Isochromosome 6p, a unique chromosomal abnormality in retinoblastoma: verification by standard staining techniques, new densitometric methods, and somatic cell hybridization. Hum. Genet. 66:46-53
    • (1984) Hum. Genet. , vol.66 , pp. 46-53
    • Squire, J.1    Phillips, R.A.2    Boyce, S.3    Godbout, R.4    Rogers, B.5    Gallie, B.L.6
  • 20
    • 84962994396 scopus 로고
    • Homogeneously staining region in a retinoblastoma cell line: Relevance to tumor initiation and progression
    • Gilbert F, Balaban G, Breg WR, Gallie B, Reid T, Nichols W. 1981. Homogeneously staining region in a retinoblastoma cell line: relevance to tumor initiation and progression. J. Natl. Cancer Inst. 67:301-6
    • (1981) J. Natl. Cancer Inst. , vol.67 , pp. 301-306
    • Gilbert, F.1    Balaban, G.2    Breg, W.R.3    Gallie, B.4    Reid, T.5    Nichols, W.6
  • 21
    • 0026483890 scopus 로고
    • Genetics and cytogenetics of retinoblastoma
    • Cowell JK, Hogg A. 1992. Genetics and cytogenetics of retinoblastoma. Cancer Genet. Cytogenet. 64:1-11
    • (1992) Cancer Genet. Cytogenet. , vol.64 , pp. 1-11
    • Cowell, J.K.1    Hogg, A.2
  • 22
    • 0026718136 scopus 로고
    • Detection of heterozygous mutations in the RB1 gene in retinoblastoma patients using single-strand conformation polymorphism analysis and polymerase chain reaction sequencing
    • Hogg A, Onadim Z, Baird PN, Cowell JK. 1992. Detection of heterozygous mutations in the RB1 gene in retinoblastoma patients using single-strand conformation polymorphism analysis and polymerase chain reaction sequencing. Oncogene 7:1445-51
    • (1992) Oncogene , vol.7 , pp. 1445-1451
    • Hogg, A.1    Onadim, Z.2    Baird, P.N.3    Cowell, J.K.4
  • 23
  • 24
    • 1642352674 scopus 로고    scopus 로고
    • Constitutional genomic instability, chromosome aberrations in tumor cells and retinoblastoma
    • Amare Kadam PS, Ghule P, Jose J, Bamne M, Kurkure P, et al. 2004. Constitutional genomic instability, chromosome aberrations in tumor cells and retinoblastoma. Cancer Genet. Cytogenet. 150:33-43
    • (2004) Cancer Genet. Cytogenet. , vol.150 , pp. 33-43
    • Amare Kadam, P.S.1    Ghule, P.2    Jose, J.3    Bamne, M.4    Kurkure, P.5
  • 25
    • 34249004558 scopus 로고    scopus 로고
    • One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma
    • Corson TW, Gallie BL. 2007. One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma. Genes Chromosomes Cancer 46:617-34
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 617-634
    • Corson, T.W.1    Gallie, B.L.2
  • 26
    • 27144521756 scopus 로고    scopus 로고
    • Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma
    • Grasemann C, Gratias S, Stephan H, Schuler A, Schramm A, et al. 2005. Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma. Oncogene 24:6441-49
    • (2005) Oncogene , vol.24 , pp. 6441-6449
    • Grasemann, C.1    Gratias, S.2    Stephan, H.3    Schuler, A.4    Schramm, A.5
  • 28
    • 1542426648 scopus 로고    scopus 로고
    • Amplification and overexpression of E2F3 in human bladder cancer
    • Feber A, Clark J, Goodwin G, Dodson AR, Smith PH, et al. 2004. Amplification and overexpression of E2F3 in human bladder cancer. Oncogene 23:1627-30
    • (2004) Oncogene , vol.23 , pp. 1627-1630
    • Feber, A.1    Clark, J.2    Goodwin, G.3    Dodson, A.R.4    Smith, P.H.5
  • 29
    • 33750221102 scopus 로고    scopus 로고
    • E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer
    • Oeggerli M, Schraml P, Ruiz C, Bloch M, Novotny H, et al. 2006. E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer. Oncogene 25:6538-43
    • (2006) Oncogene , vol.25 , pp. 6538-6543
    • Oeggerli, M.1    Schraml, P.2    Ruiz, C.3    Bloch, M.4    Novotny, H.5
  • 30
    • 4043119132 scopus 로고    scopus 로고
    • Transcription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcome
    • Foster CS, Falconer A, Dodson AR, Norman AR, Dennis N, et al. 2004. Transcription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcome. Oncogene 23:5871-79
    • (2004) Oncogene , vol.23 , pp. 5871-5879
    • Foster, C.S.1    Falconer, A.2    Dodson, A.R.3    Norman, A.R.4    Dennis, N.5
  • 31
    • 33751120208 scopus 로고    scopus 로고
    • Nuclear overexpression of the E2F3 transcription factor in human lung cancer
    • Cooper CS, Nicholson AG, Foster C, Dodson A, Edwards S, et al. 2006. Nuclear overexpression of the E2F3 transcription factor in human lung cancer. Lung Cancer 54:155-62
    • (2006) Lung Cancer , vol.54 , pp. 155-162
    • Cooper, C.S.1    Nicholson, A.G.2    Foster, C.3    Dodson, A.4    Edwards, S.5
  • 33
    • 0026560593 scopus 로고
    • The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA
    • Von Lindern M, Fornerod M, van Baal S, Jaegle M, de Wit T, et al. 1992. The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. Mol. Cell. Biol. 12:1687-97
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1687-1697
    • Von Lindern, M.1    Fornerod, M.2    Van Baal, S.3    Jaegle, M.4    De Wit, T.5
  • 34
    • 84880947578 scopus 로고    scopus 로고
    • DEK over expression as an independent biomarker for poor prognosis in colorectal cancer
    • Lin L, Piao J, GaoW, Piao Y, Jin G, et al. 2013. DEK over expression as an independent biomarker for poor prognosis in colorectal cancer. BMC Cancer 13:366
    • (2013) BMC Cancer , vol.13 , pp. 366
    • Lin, L.1    Piao, J.2    Gaow Piao, Y.3    Jin, G.4
  • 35
    • 0037299508 scopus 로고    scopus 로고
    • Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome
    • Lillington DM, Kingston JE, Coen PG, Price E, Hungerford J, et al. 2003. Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome. Genes Chromosomes Cancer 36:121-28
    • (2003) Genes Chromosomes Cancer , vol.36 , pp. 121-128
    • Lillington, D.M.1    Kingston, J.E.2    Coen, P.G.3    Price, E.4    Hungerford, J.5
  • 36
    • 0035105451 scopus 로고    scopus 로고
    • Marked differences in unilateral isolated retinoblastomas from young and older children studied by comparative genomic hybridization
    • Herzog S, Lohmann DR, Buiting K, Sch uler A, Horsthemke B, et al. 2001. Marked differences in unilateral isolated retinoblastomas from young and older children studied by comparative genomic hybridization. Hum. Genet. 108:98-104
    • (2001) Hum. Genet. , vol.108 , pp. 98-104
    • Herzog, S.1    Lohmann, D.R.2    Buiting, K.3    Schuler, A.4    Horsthemke, B.5
  • 37
    • 0030885299 scopus 로고    scopus 로고
    • Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome
    • Nakagawa T, Tanaka Y, Matsuoka E, Kondo S, Okada Y, et al. 1997. Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. PNAS 94:9654-59
    • (1997) PNAS , vol.94 , pp. 9654-9659
    • Nakagawa, T.1    Tanaka, Y.2    Matsuoka, E.3    Kondo, S.4    Okada, Y.5
  • 38
    • 84872135577 scopus 로고    scopus 로고
    • Kinesin family member 14 is a candidate prognostic marker for outcome of glioma patients
    • Wang Q, Wang L, Li D, Deng J, Zhao Z, et al. 2013. Kinesin family member 14 is a candidate prognostic marker for outcome of glioma patients. Cancer Epidemiol. 37:79-84
    • (2013) Cancer Epidemiol. , vol.37 , pp. 79-84
    • Wang, Q.1    Wang, L.2    Li, D.3    Deng, J.4    Zhao, Z.5
  • 39
    • 84857481599 scopus 로고    scopus 로고
    • Kinesin family member 14: An independent prognostic marker and potential therapeutic target for ovarian cancer
    • Theriault BL, Pajovic S, Bernardini MQ, Shaw PA, Gallie BL. 2012. Kinesin family member 14: an independent prognostic marker and potential therapeutic target for ovarian cancer. Int. J. Cancer 130:1844-54
    • (2012) Int. J. Cancer , vol.130 , pp. 1844-1854
    • Theriault, B.L.1    Pajovic, S.2    Bernardini, M.Q.3    Shaw, P.A.4    Gallie, B.L.5
  • 40
    • 33746328114 scopus 로고    scopus 로고
    • KIF14 mRNA expression is a predictor of grade and outcome in breast cancer
    • Corson TW, Gallie BL. 2006. KIF14 mRNA expression is a predictor of grade and outcome in breast cancer. Int. J. Cancer 119:1088-94
    • (2006) Int. J. Cancer , vol.119 , pp. 1088-1094
    • Corson, T.W.1    Gallie, B.L.2
  • 44
    • 33750218270 scopus 로고    scopus 로고
    • A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH
    • Roylance R, Gorman P, Papior T, Wan Y-L, Ives M, et al. 2006. A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH. Oncogene 25:6544-53
    • (2006) Oncogene , vol.25 , pp. 6544-6553
    • Roylance, R.1    Gorman, P.2    Papior, T.3    Wan, Y.-L.4    Ives, M.5
  • 45
    • 71949117092 scopus 로고    scopus 로고
    • Changes in retinoblastoma cell adhesion associated with optic nerve invasion
    • Laurie N, Mohan A, McEvoy J, Reed D, Zhang J, et al. 2009. Changes in retinoblastoma cell adhesion associated with optic nerve invasion. Mol. Cell. Biol. 29:6268-82
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 6268-6282
    • Laurie, N.1    Mohan, A.2    McEvoy, J.3    Reed, D.4    Zhang, J.5
  • 46
    • 0030598937 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 17 and mutation of the p53 gene in retinoblastoma
    • Kato MV, Shimizu T, Ishizaki K, Kaneko A, Yandell DW, et al. 1996. Loss of heterozygosity on chromosome 17 and mutation of the p53 gene in retinoblastoma. Cancer Lett. 106:75-82
    • (1996) Cancer Lett. , vol.106 , pp. 75-82
    • Kato, M.V.1    Shimizu, T.2    Ishizaki, K.3    Kaneko, A.4    Yandell, D.W.5
  • 47
    • 33847271089 scopus 로고    scopus 로고
    • Coping with stress: Multiple ways to activate p53
    • Horn HF, Vousden KH. 2007. Coping with stress: multiple ways to activate p53. Oncogene 26:1306-16
    • (2007) Oncogene , vol.26 , pp. 1306-1316
    • Horn, H.F.1    Vousden, K.H.2
  • 49
    • 13144249170 scopus 로고    scopus 로고
    • Mdmx and Mdm2: Brothers in arms?
    • Marine J-C, Jochemsen AG. 2004. Mdmx and Mdm2: brothers in arms?. Cell Cycle 3:900-4
    • (2004) Cell Cycle , vol.3 , pp. 900-904
    • Marine, J.-C.1    Jochemsen, A.G.2
  • 52
    • 79958815839 scopus 로고    scopus 로고
    • Coexpression of normally incompatible developmental pathways in retinoblastoma genesis
    • McEvoy J, Flores-Otero J, Zhang J, Nemeth K, Brennan R, et al. 2011. Coexpression of normally incompatible developmental pathways in retinoblastoma genesis. Cancer Cell 20:260-75
    • (2011) Cancer Cell , vol.20 , pp. 260-275
    • McEvoy, J.1    Flores-Otero, J.2    Zhang, J.3    Nemeth, K.4    Brennan, R.5
  • 53
    • 84865187027 scopus 로고    scopus 로고
    • Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma
    • McEvoy J, Ulyanov A, Brennan R, Wu G, Pounds S, et al. 2012. Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. PLOS ONE 7:e42739
    • (2012) PLOS ONE , vol.7 , pp. e42739
    • McEvoy, J.1    Ulyanov, A.2    Brennan, R.3    Wu, G.4    Pounds, S.5
  • 54
    • 77953995002 scopus 로고    scopus 로고
    • Covalent histone modifications-miswritten, misinterpreted and mis-erased in human cancers
    • Chi P, Allis CD, Wang GG. 2010. Covalent histone modifications-miswritten, misinterpreted and mis-erased in human cancers. Nat. Rev. Cancer 10:457-69
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 457-469
    • Chi, P.1    Allis, C.D.2    Wang, G.G.3
  • 55
    • 34547201576 scopus 로고    scopus 로고
    • A genome-wideRNAinterference screen identifies putative chromatin regulators essential for E2F repression
    • Lu J, Ruhf M-L, Perrimon N, Leder P. 2007.A genome-wideRNAinterference screen identifies putative chromatin regulators essential for E2F repression. PNAS 104:9381-86
    • (2007) PNAS , vol.104 , pp. 9381-9386
    • Lu, J.1    Ruhf, M.-L.2    Perrimon, N.3    Leder, P.4
  • 56
    • 51349116001 scopus 로고    scopus 로고
    • Amammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
    • Benetti R, Gonzalo S, Jaco I, Munoz P, Gonzalez S, et al. 2008. Amammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat. Struct. Mol. Biol. 15:998
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 998
    • Benetti, R.1    Gonzalo, S.2    Jaco, I.3    Munoz, P.4    Gonzalez, S.5
  • 57
    • 40349108695 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex
    • Wen H, Andrejka L, Ashton J, Karess R, Lipsick JS. 2008. Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex. Genes Dev. 22:601-14
    • (2008) Genes Dev. , vol.22 , pp. 601-614
    • Wen, H.1    Andrejka, L.2    Ashton, J.3    Karess, R.4    Lipsick, J.S.5
  • 58
    • 67749108048 scopus 로고    scopus 로고
    • SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity
    • Bourgo RJ, Siddiqui H, Fox S, Solomon D, Sansam CG, et al. 2009. SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity. Mol. Biol. Cell 20:3192-99
    • (2009) Mol. Biol. Cell , vol.20 , pp. 3192-3199
    • Bourgo, R.J.1    Siddiqui, H.2    Fox, S.3    Solomon, D.4    Sansam, C.G.5
  • 59
    • 25144491542 scopus 로고    scopus 로고
    • Role of Rb family in the epigenetic definition of chromatin
    • Gonzalo S, Blasco MA. 2005. Role of Rb family in the epigenetic definition of chromatin. Cell Cycle 4:752-55
    • (2005) Cell Cycle , vol.4 , pp. 752-755
    • Gonzalo, S.1    Blasco, M.A.2
  • 60
    • 33846283385 scopus 로고    scopus 로고
    • The evolution of gene regulation by transcription factors and microRNAs
    • Chen K, Rajewsky N. 2007. The evolution of gene regulation by transcription factors and microRNAs. Nat. Rev. Genet. 8:93-103
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 93-103
    • Chen, K.1    Rajewsky, N.2
  • 61
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. 2009. MicroRNAs: target recognition and regulatory functions. Cell 136:215-33
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 62
    • 57449085536 scopus 로고    scopus 로고
    • Identification ofmiRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis
    • Zhao JJ, Yang J, Lin J, Yao N, Zhu Y, et al. 2009. Identification ofmiRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis. Child's Nerv. Syst. 25:13-20
    • (2009) Child's Nerv. Syst. , vol.25 , pp. 13-20
    • Zhao, J.J.1    Yang, J.2    Lin, J.3    Yao, N.4    Zhu, Y.5
  • 63
    • 84860417150 scopus 로고    scopus 로고
    • 2011. MiR-17-92 cooperates with RB pathway mutations to promote retinoblastoma
    • Conkrite K, Sundby M, Mukai S, Thomson JM, Mu D, et al. 2011. miR-17-92 cooperates with RB pathway mutations to promote retinoblastoma. Genes Dev. 25:1734-45
    • Genes Dev. , vol.25 , pp. 1734-1745
    • Conkrite, K.1    Sundby, M.2    Mukai, S.3    Thomson, J.M.4    Mu, D.5
  • 64
    • 84864280599 scopus 로고    scopus 로고
    • Identification of retinoblastoma related genes with shortest path in a protein-protein interaction network
    • Li BQ, Zhang J, Huang T, Zhang L, Cai YD. 2012. Identification of retinoblastoma related genes with shortest path in a protein-protein interaction network. Biochimie 94:1910-17
    • (2012) Biochimie , vol.94 , pp. 1910-1917
    • Li, B.Q.1    Zhang, J.2    Huang, T.3    Zhang, L.4    Cai, Y.D.5
  • 66
    • 80053308600 scopus 로고    scopus 로고
    • Differential profiles ofmicroRNAs in retinoblastoma cell lines of different proliferation and adherence patterns
    • Jo DH, Kim JH, Park WY, Kim KW, Yu YS. 2011. Differential profiles ofmicroRNAs in retinoblastoma cell lines of different proliferation and adherence patterns. J. Pediatr. Hematol. Oncol. 33:529-33
    • (2011) J. Pediatr. Hematol. Oncol. , vol.33 , pp. 529-533
    • Jo, D.H.1    Kim, J.H.2    Park, W.Y.3    Kim, K.W.4    Yu, Y.S.5
  • 68
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee YS, Dutta A. 2007. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev. 21:1025-30
    • (2007) Genes Dev. , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 69
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • Mayr C, Hemann MT, Bartel DP. 2007. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315:1576-79
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 70
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
    • Sampson VB, Rong NH, Han J, Yang Q, Aris V, et al. 2007. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res. 67:9762-70
    • (2007) Cancer Res. , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3    Yang, Q.4    Aris, V.5
  • 71
    • 77649340617 scopus 로고    scopus 로고
    • Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas
    • Mu G, Liu H, Zhou F, Xu X, Jiang H, et al. 2010. Correlation of overexpression ofHMGA1andHMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. Hum. Pathol. 41:493-502
    • (2010) Hum. Pathol. , vol.41 , pp. 493-502
    • Mu, G.1    Liu, H.2    Zhou, F.3    Xu, X.4    Jiang, H.5
  • 72
    • 36749005527 scopus 로고    scopus 로고
    • Using expression profiling data to identify human microRNA targets
    • Huang JC, Babak T, Corson TW, Chua G, Khan S, et al. 2007. Using expression profiling data to identify human microRNA targets. Nat. Methods 4:1045-49
    • (2007) Nat. Methods , vol.4 , pp. 1045-1049
    • Huang, J.C.1    Babak, T.2    Corson, T.W.3    Chua, G.4    Khan, S.5
  • 73
    • 84870360348 scopus 로고    scopus 로고
    • Differentially expressed miRNAs in retinoblastoma
    • Martin J, Bryar P, Mets M, Weinstein J, Jones A, et al. 2013. Differentially expressed miRNAs in retinoblastoma. Gene 512:294-99
    • (2013) Gene , vol.512 , pp. 294-299
    • Martin, J.1    Bryar, P.2    Mets, M.3    Weinstein, J.4    Jones, A.5
  • 74
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, et al. 2007. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell 26:745-52
    • (2007) Mol. Cell , vol.26 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3    Ramachandran, K.4    Mullendore, M.5
  • 75
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, de Stanchina E, Xuan Z, et al. 2007. A microRNA component of the p53 tumour suppressor network. Nature 447:1130-34
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3    De Stanchina, E.4    Xuan, Z.5
  • 76
    • 34249822779 scopus 로고    scopus 로고
    • Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
    • Raver-Shapira N, Marciano E, Meiri E, Spector Y, Rosenfeld N, et al. 2007. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol. Cell 26:731-43
    • (2007) Mol. Cell , vol.26 , pp. 731-743
    • Raver-Shapira, N.1    Marciano, E.2    Meiri, E.3    Spector, Y.4    Rosenfeld, N.5
  • 77
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-Arrest
    • Tarasov V, Jung P, Verdoodt B, Lodygin D, Epanchintsev A, et al. 2007. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-Arrest. Cell Cycle 6:1586-93
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5
  • 78
    • 84860400268 scopus 로고    scopus 로고
    • MiR than meets the eye
    • Sage J, Ventura A. 2011. miR than meets the eye. Genes Dev. 25:1663-67
    • (2011) Genes Dev. , vol.25 , pp. 1663-1667
    • Sage, J.1    Ventura, A.2
  • 79
    • 39749143354 scopus 로고    scopus 로고
    • Targeted deletion reveals essential and overlapping functions of the miR-17-92 family of miRNA clusters
    • Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, et al. 2008. Targeted deletion reveals essential and overlapping functions of the miR-17-92 family of miRNA clusters. Cell 132:875-86
    • (2008) Cell , vol.132 , pp. 875-886
    • Ventura, A.1    Young, A.G.2    Winslow, M.M.3    Lintault, L.4    Meissner, A.5
  • 81
    • 77954382780 scopus 로고    scopus 로고
    • Mir-17-92, a cluster of miRNAs in the midst of the cancer network
    • Olive V, Jiang I, He L. 2010. mir-17-92, a cluster of miRNAs in the midst of the cancer network. Int. J. Biochem. Cell Biol. 42:1348-54
    • (2010) Int. J. Biochem. Cell Biol. , vol.42 , pp. 1348-1354
    • Olive, V.1    Jiang, I.2    He, L.3
  • 83
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods K, Thomson JM, Hammond SM. 2007. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem. 282:2130-34
    • (2007) J. Biol. Chem. , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 84
    • 84865785877 scopus 로고    scopus 로고
    • Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation
    • Nittner D, Lambertz I, Clermont F, Mestdagh P, K ohler C, et al. 2012. Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation. Nat. Cell Biol. 14:958-65
    • (2012) Nat. Cell Biol. , vol.14 , pp. 958-965
    • Nittner, D.1    Lambertz, I.2    Clermont, F.3    Mestdagh, P.4    Kohler, C.5
  • 85
    • 84876074820 scopus 로고    scopus 로고
    • More epigenetic hits than meets the eye: MicroRNAs and genes associated with the tumorigenesis of retinoblastoma
    • Reis AH, Vargas FR, Lemos B. 2012. More epigenetic hits than meets the eye: microRNAs and genes associated with the tumorigenesis of retinoblastoma. Front. Genet. 3:284
    • (2012) Front. Genet. , vol.3 , pp. 284
    • Reis, A.H.1    Vargas, F.R.2    Lemos, B.3
  • 86
    • 0024365892 scopus 로고
    • Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
    • Greger V, Passarge E, Hopping W, Messmer E, Horsthemke B. 1989. Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet. 83:155-58
    • (1989) Hum. Genet. , vol.83 , pp. 155-158
    • Greger, V.1    Passarge, E.2    Hopping, W.3    Messmer, E.4    Horsthemke, B.5
  • 88
    • 0027537296 scopus 로고
    • CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene
    • Ohtani-Fujita N, Fujita T, Aoike A, Osifchin NE, Robbins PD, Sakai T. 1993. CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene 8:1063-67
    • (1993) Oncogene , vol.8 , pp. 1063-1067
    • Ohtani-Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5    Sakai, T.6
  • 90
    • 0037322272 scopus 로고    scopus 로고
    • Sensitive and efficient detection of RB1 gene mutations enhances care for families with retinoblastoma
    • Richter S, Vandezande K, Chen N, Zhang K, Sutherland J, et al. 2003. Sensitive and efficient detection of RB1 gene mutations enhances care for families with retinoblastoma. Am. J. Hum. Genet. 72:253-69
    • (2003) Am. J. Hum. Genet. , vol.72 , pp. 253-269
    • Richter, S.1    Vandezande, K.2    Chen, N.3    Zhang, K.4    Sutherland, J.5
  • 92
    • 18444379044 scopus 로고    scopus 로고
    • Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines
    • Harada K, Toyooka S, Maitra A, Maruyama R, Toyooka KO, et al. 2002. Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines. Oncogene 21:4345-49
    • (2002) Oncogene , vol.21 , pp. 4345-4349
    • Harada, K.1    Toyooka, S.2    Maitra, A.3    Maruyama, R.4    Toyooka, K.O.5
  • 93
    • 20144370134 scopus 로고    scopus 로고
    • Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma
    • Choy KW, Lee TC, Cheung KF, Fan DS, Lo KW, et al. 2005. Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma. Neoplasia 7:200-6
    • (2005) Neoplasia , vol.7 , pp. 200-206
    • Choy, K.W.1    Lee, T.C.2    Cheung, K.F.3    Fan, D.S.4    Lo, K.W.5
  • 94
    • 75749127315 scopus 로고    scopus 로고
    • Downregulation and aberrant promoter methylation of p16INK4A: A possible novel heritable susceptibility marker to retinoblastoma
    • Indovina P, Acquaviva A, De Falco G, Rizzo V, Onnis A, et al. 2010. Downregulation and aberrant promoter methylation of p16INK4A: a possible novel heritable susceptibility marker to retinoblastoma. J. Cell. Physiol. 223:143-50
    • (2010) J. Cell. Physiol. , vol.223 , pp. 143-150
    • Indovina, P.1    Acquaviva, A.2    De Falco, G.3    Rizzo, V.4    Onnis, A.5
  • 95
    • 84875810807 scopus 로고    scopus 로고
    • Characterisation of retinoblastomas without RB1 mutations: Genomic, gene expression, and clinical studies
    • Rushlow DE, Mol BM, Kennett JY, Yee S, Pajovic S, et al. 2013. Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies. Lancet Oncol. 14:327-34
    • (2013) Lancet Oncol. , vol.14 , pp. 327-334
    • Rushlow, D.E.1    Mol, B.M.2    Kennett, J.Y.3    Yee, S.4    Pajovic, S.5
  • 96
    • 0030747725 scopus 로고    scopus 로고
    • Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals
    • Sears R, Ohtani K, Nevins JR. 1997. Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals. Mol. Cell. Biol. 17:5227-35
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5227-5235
    • Sears, R.1    Ohtani, K.2    Nevins, J.R.3
  • 97
    • 0034014308 scopus 로고    scopus 로고
    • Complex transcriptional regulatory mechanisms control expression of the E2F3 locus
    • Adams MR, Sears R, Nuckolls F, Leone G, Nevins JR. 2000. Complex transcriptional regulatory mechanisms control expression of the E2F3 locus. Mol. Cell. Biol. 20:3633-39
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3633-3639
    • Adams, M.R.1    Sears, R.2    Nuckolls, F.3    Leone, G.4    Nevins, J.R.5
  • 98
    • 17944375816 scopus 로고    scopus 로고
    • Myc requires distinct E2F activities to induce S phase and apoptosis
    • Leone G, Sears R, Huang E, Rempel R, Nuckolls F, et al. 2001. Myc requires distinct E2F activities to induce S phase and apoptosis. Mol. Cell 8:105-13
    • (2001) Mol. Cell , vol.8 , pp. 105-113
    • Leone, G.1    Sears, R.2    Huang, E.3    Rempel, R.4    Nuckolls, F.5
  • 99
    • 78650959663 scopus 로고    scopus 로고
    • Massive genomic rearrangement acquired in a single catastrophic event during cancer development
    • Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR, et al. 2011. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144:27-40
    • (2011) Cell , vol.144 , pp. 27-40
    • Stephens, P.J.1    Greenman, C.D.2    Fu, B.3    Yang, F.4    Bignell, G.R.5


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