BenzylglucosinolateDerived Isothiocyanate from Tropaeolum majus Reduces Gluconeogenic Gene and Protein Expression in Human Cells

PLoS ONE

Volumn 11, Issue 9, 2016, Pages

  Guzmán Pérez, Valentina ^a,b   Bumke Vogt, Christiane ^a,c,d   Schreiner, Monika ^d   Mewis, Inga ^d   Borchert, Andrea ^a   Pfeiffer, Andreas F H ^a,c  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d LEIBNIZ INSTITUTE OF VEGETABLE AND ORNAMENTAL CROPS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; BENZYL ISOTHIOCYANATE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUCOSINOLATE; GREEN FLUORESCENT PROTEIN; INSULIN; PROTEIN KINASE B; SIRTUIN 1; SMALL INTERFERING RNA; THIOGLUCOSIDASE; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR NRF2; ANTIDIABETIC AGENT; ANTIOXIDANT; BENZYLGLUCOSINOLIC ACID; FOXO1 PROTEIN, HUMAN; HYBRID PROTEIN; ISOTHIOCYANIC ACID DERIVATIVE; NFE2L2 PROTEIN, HUMAN; PCK2 PROTEIN, HUMAN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); SIRT1 PROTEIN, HUMAN; THIOCYANIC ACID DERIVATIVE; THIOGLYCOSIDE;

ARTICLE; BIOCHEMICAL COMPOSITION; CONTROLLED STUDY; DOWN REGULATION; DRUG DETERMINATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; HEPG2 CELL LINE; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NON INSULIN DEPENDENT DIABETES MELLITUS; OSTEOSARCOMA CELL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TROPAEOLUM MAJUS; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL SURVIVAL; CHEMISTRY; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; GENE SILENCING; GENETICS; HEP-G2 CELL LINE; MEDICINAL PLANT; METABOLISM; NUCLEOCYTOPLASMIC TRANSPORT; PHYSIOLOGY; PROTEIN TRANSPORT; TROPAEOLUM;

ACETYLCYSTEINE; ACTIVE TRANSPORT, CELL NUCLEUS; ANTIOXIDANTS; CELL LINE; CELL SURVIVAL; DIABETES MELLITUS, TYPE 2; FORKHEAD BOX PROTEIN O1; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GLUCONEOGENESIS; GLUCOSE-6-PHOSPHATASE; HEP G2 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; ISOTHIOCYANATES; NF-E2-RELATED FACTOR 2; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PLANTS, MEDICINAL; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; SIRTUIN 1; THIOCYANATES; THIOGLUCOSIDES; TROPAEOLUM;

EID: 84991594288     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0162397     Document Type: Article

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