Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons

Science

Volumn 319, Issue 5870, 2008, Pages 1665-1668

  Yuan, Zengqiang ^a,c   Becker, Esther B E ^a   Merlo, Paola ^a   Yamada, Tomoko ^a   DiBacco, Sara ^a   Konishi, Yoshiyuki ^a   Schaefer, Erik M ^b   Bonni, Azad ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b INVITROGEN CORPORATION   (United States)

^c INSTITUTE OF BIOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 1; POLO LIKE KINASE; PROTEIN 14 3 3; ROSCOVITINE; SERINE; TRANSCRIPTION FACTOR FKHR;

BRAIN; DEVELOPMENTAL BIOLOGY; ENZYME ACTIVITY; NERVOUS SYSTEM DISORDER; PROTEIN;

ARTICLE; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MITOSIS; NERVE CELL; NERVE DEGENERATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELLS, CULTURED; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; MICE; NERVE TISSUE PROTEINS; NEURONS; NIH 3T3 CELLS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; SERINE; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 41149160386     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1152337     Document Type: Article

References (12)

1. Y. Konishi, M. Lehtinen, N. Donovan, A. Bonni, Mol. Cell 9, 1005 (2002).
2. E. B. Becker, A. Bonni, Prog. Neurobiol. 72, 1 (2004).
3. M. Kurita, T. Kuwajima, I. Nishimura, K. Yoshikawa, J. Neurosci. 26, 12003 (2006).
4. V. Khurana et al., Curr. Biol. 16, 230 (2006).
5. I. Vincent, G. Jicha, M. Rosado, D. W. Dickson, J. Neurosci. 17, 3588 (1997).
6. J. Busser, D. S. Geldmacher, K. Herrup, J. Neurosci. 18, 2801 (1998).
7. L. P. Van Der Heide, M. F. Hoekman, M. P. Smidt, Biochem. J. 380, 297 (2004).
8. B. M. Burgering, G. J. Kops, Trends Biochem. Sci. 27, 352 (2002).
9. See supporting material on Science Online.
10. H. Huang, K. M. Regan, Z. Lou, J. Chen, D. J. Tindall, Science 314, 294 (2006).
11. B. Alvarez, A. C. Martinez, B. M. Burgering, A. C. Carrera, Nature 413, 744 (2001).
12. We thank J. W. Harper, S. Puram, and other members of the Bonni laboratory for helpful discussions and critical reading of the manuscript. Supported by a pilot grant from the Paul Glenn Laboratories (A.B.), NIH grant NS047188 (A.B.), and a Uehara Memorial Foundation fellowship (T.Y.).