-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay, J., Shin, H. R., Bray, F., Forman, D., Mathers, C., & Parkin, D. M. (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127, 2893-2917.
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
16644398719
-
Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group
-
Rudd, R. M., Gower, N. H., Spiro, S. G., Eisen, T. G., Harper, P. G., Littler, J. A., et al. (2005). Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group. J Clin Oncol, 23, 142-153.
-
(2005)
J Clin Oncol
, vol.23
, pp. 142-153
-
-
Rudd, R.M.1
Gower, N.H.2
Spiro, S.G.3
Eisen, T.G.4
Harper, P.G.5
Littler, J.A.6
Hatton, M.7
Johnson, P.W.8
Martin, W.M.9
Rankin, E.M.10
-
3
-
-
19944413630
-
Multicentre randomised phase III study comparing the same dose and schedule of cisplatin plus the same schedule of vinorelbine or gemcitabine in advanced non-small cell lung cancer
-
Martoni, A., Marino, A., Sperandi, F., Giaquinta, S., Di Fabio, F., Melotti, B., et al. (2005). Multicentre randomised phase III study comparing the same dose and schedule of cisplatin plus the same schedule of vinorelbine or gemcitabine in advanced non-small cell lung cancer. Eur J Cancer, 41, 81-92.
-
(2005)
Eur J Cancer
, vol.41
, pp. 81-92
-
-
Martoni, A.1
Marino, A.2
Sperandi, F.3
Giaquinta, S.4
Di Fabio, F.5
Melotti, B.6
Guaraldi, M.7
Palomba, G.8
Preti, P.9
Petralia, A.10
-
4
-
-
17844372539
-
Critical update and emerging trends in epidermal growth factor receptor targeting in cancer
-
Baselga, J., & Arteaga, C. L. (2005). Critical update and emerging trends in epidermal growth factor receptor targeting in cancer. J Clin Oncol, 23, 2445-2459.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2445-2459
-
-
Baselga, J.1
Arteaga, C.L.2
-
5
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
Thatcher, N., Chang, A., Parikh, P., Rodrigues Pereira, J., Ciuleanu, T., von Pawel, J., et al. (2005). Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet, 366, 1527-1537.
-
(2005)
Lancet
, vol.366
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
Rodrigues Pereira, J.4
Ciuleanu, T.5
von Pawel, J.6
Thongprasert, S.7
Tan, E.H.8
Pemberton, K.9
Archer, V.10
-
6
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
-
Fukuoka, M., Yano, S., Giaccone, G., Tamura, T., Nakagawa, K., Douillard, J. Y., et al. (2003). Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol, 21, 2237-2246.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
Tamura, T.4
Nakagawa, K.5
Douillard, J.Y.6
Nishiwaki, Y.7
Vansteenkiste, J.8
Kudoh, S.9
Rischin, D.10
-
7
-
-
79952376771
-
Treatment of non-small-cell lung cancer with erlotinib or gefitinib
-
Cataldo, V. D., Gibbons, D. L., Perez-Soler, R., & Quintas-Cardama, A. (2011). Treatment of non-small-cell lung cancer with erlotinib or gefitinib. N Engl J Med, 364, 947-955.
-
(2011)
N Engl J Med
, vol.364
, pp. 947-955
-
-
Cataldo, V.D.1
Gibbons, D.L.2
Perez-Soler, R.3
Quintas-Cardama, A.4
-
8
-
-
77956268839
-
Understanding resistance to EGFR inhibitors-impact on future treatment strategies
-
Wheeler, D. L., Dunn, E. F., & Harari, P. M. (2010). Understanding resistance to EGFR inhibitors-impact on future treatment strategies. Nat Rev Clin Oncol, 7, 493-507.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 493-507
-
-
Wheeler, D.L.1
Dunn, E.F.2
Harari, P.M.3
-
9
-
-
66749170767
-
Are isothiocyanates potential anti-cancer drugs?
-
Wu, X., Zhou, Q. H., & Xu, K. (2009). Are isothiocyanates potential anti-cancer drugs? Acta Pharmacol Sinica, 30, 501-512.
-
(2009)
Acta Pharmacol Sinica
, vol.30
, pp. 501-512
-
-
Wu, X.1
Zhou, Q.H.2
Xu, K.3
-
10
-
-
53249149116
-
Induction of apoptosis by phenethyl isothiocyanate in cells overexpressing Bcl-XL
-
Cuddihy, S. L., Brown, K. K., Thomson, S. J., & Hampton, M. B. (2008). Induction of apoptosis by phenethyl isothiocyanate in cells overexpressing Bcl-XL. Cancer Lett, 271, 215-221.
-
(2008)
Cancer Lett
, vol.271
, pp. 215-221
-
-
Cuddihy, S.L.1
Brown, K.K.2
Thomson, S.J.3
Hampton, M.B.4
-
11
-
-
52049113028
-
Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis
-
Mi, L., Xiao, Z., Hood, B. L., Dakshanamurthy, S., Wang, X., Govind, S., et al. (2008). Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis. J Biological Chem, 283, 22136-22146.
-
(2008)
J Biological Chem
, vol.283
, pp. 22136-22146
-
-
Mi, L.1
Xiao, Z.2
Hood, B.L.3
Dakshanamurthy, S.4
Wang, X.5
Govind, S.6
Conrads, T.P.7
Veenstra, T.D.8
Chung, F.L.9
-
12
-
-
80053925842
-
Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-alpha/VEGF/Rho-GTPases: pivotal role of STAT-3
-
Boreddy, S. R., Sahu, R. P., & Srivastava, S. K. (2011). Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-alpha/VEGF/Rho-GTPases: pivotal role of STAT-3. Plos One, 6, e25799.
-
(2011)
Plos One
, vol.6
-
-
Boreddy, S.R.1
Sahu, R.P.2
Srivastava, S.K.3
-
13
-
-
77957958015
-
Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound beta-phenylethyl isothiocyanate
-
Hu, Y., Lu, W., Chen, G., Zhang, H., Jia, Y., Wei, Y., et al. (2010). Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound beta-phenylethyl isothiocyanate. Blood, 116, 2732-2741.
-
(2010)
Blood
, vol.116
, pp. 2732-2741
-
-
Hu, Y.1
Lu, W.2
Chen, G.3
Zhang, H.4
Jia, Y.5
Wei, Y.6
Yang, H.7
Zhang, W.8
Fiskus, W.9
Bhalla, K.10
-
14
-
-
52649153465
-
Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism
-
Trachootham, D., Zhang, H., Zhang, W., Feng, L., Du, M., Zhou, Y., et al. (2008). Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism. Blood, 112, 1912-1922.
-
(2008)
Blood
, vol.112
, pp. 1912-1922
-
-
Trachootham, D.1
Zhang, H.2
Zhang, W.3
Feng, L.4
Du, M.5
Zhou, Y.6
Chen, Z.7
Pelicano, H.8
Plunkett, W.9
Wierda, W.G.10
-
15
-
-
45149100643
-
Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism
-
Zhang, H., Trachootham, D., Lu, W., Carew, J., Giles, F. J., Keating, M. J., et al. (2008). Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism. Leukemia, 22, 1191-1199.
-
(2008)
Leukemia
, vol.22
, pp. 1191-1199
-
-
Zhang, H.1
Trachootham, D.2
Lu, W.3
Carew, J.4
Giles, F.J.5
Keating, M.J.6
Arlinghaus, R.B.7
Huang, P.8
-
16
-
-
82555189785
-
Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates
-
Yan, H., Zhu, Y., Liu, B., Wu, H., Li, Y., Wu, X., et al. (2011). Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates. Br J Nutr, 106(12), 1779-1791.
-
(2011)
Br J Nutr
, vol.106
, Issue.12
, pp. 1779-1791
-
-
Yan, H.1
Zhu, Y.2
Liu, B.3
Wu, H.4
Li, Y.5
Wu, X.6
Zhou, Q.7
Xu, K.8
-
17
-
-
0034662433
-
Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro
-
Xu, K., & Thornalley, P. J. (2000). Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro. Biochem Pharmacol, 60, 221-231.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 221-231
-
-
Xu, K.1
Thornalley, P.J.2
-
18
-
-
77953186750
-
Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells
-
Wu, X., Zhu, Y., Yan, H., Liu, B., Li, Y., Zhou, Q., et al. (2010). Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells. BMC Cancer, 10, 269.
-
(2010)
BMC Cancer
, vol.10
, pp. 269
-
-
Wu, X.1
Zhu, Y.2
Yan, H.3
Liu, B.4
Li, Y.5
Zhou, Q.6
Xu, K.7
-
19
-
-
24744461186
-
Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression
-
Xu, K., Guidez, F., Glasow, A., Chung, D., Petrie, K., Stegmaier, K., et al. (2005). Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression. Cancer Res, 65, 7856-7865.
-
(2005)
Cancer Res
, vol.65
, pp. 7856-7865
-
-
Xu, K.1
Guidez, F.2
Glasow, A.3
Chung, D.4
Petrie, K.5
Stegmaier, K.6
Wang, K.K.7
Zhang, J.8
Jing, Y.9
Zelent, A.10
-
20
-
-
60149103630
-
Relationship between mutations of the epidermal growth factor receptor gene and drug-resistance to Gefitinib in human lung cancer in vitro
-
Wei, W., Fan, Y., Liu, H., Wu, Z., Wan, H., Yan, Z., et al. (2009). Relationship between mutations of the epidermal growth factor receptor gene and drug-resistance to Gefitinib in human lung cancer in vitro. Zhongguo Fei Ai Za Zhi, 12, 28-32.
-
(2009)
Zhongguo Fei Ai Za Zhi
, vol.12
, pp. 28-32
-
-
Wei, W.1
Fan, Y.2
Liu, H.3
Wu, Z.4
Wan, H.5
Yan, Z.6
Xu, K.7
Zhou, Q.8
-
21
-
-
77955667737
-
Sensitization of non-small cell lung cancer cells to cisplatin by naturally occurring isothiocyanates
-
Di Pasqua, A. J., Hong, C., Wu, M. Y., McCracken, E., Wang, X., Mi, L., et al. (2010). Sensitization of non-small cell lung cancer cells to cisplatin by naturally occurring isothiocyanates. Chem Res Toxicol, 23, 1307-1309.
-
(2010)
Chem Res Toxicol
, vol.23
, pp. 1307-1309
-
-
Di Pasqua, A.J.1
Hong, C.2
Wu, M.Y.3
McCracken, E.4
Wang, X.5
Mi, L.6
Chung, F.L.7
-
22
-
-
77953174656
-
Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo
-
Xiao, D., & Singh, S. V. (2010). Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo. Pharm Res, 27, 722-731.
-
(2010)
Pharm Res
, vol.27
, pp. 722-731
-
-
Xiao, D.1
Singh, S.V.2
-
23
-
-
70349989502
-
Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells
-
Sahu, R. P., Zhang, R., Batra, S., Shi, Y., & Srivastava, S. K. (2009). Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells. Carcinogenesis, 30, 1744-1753.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1744-1753
-
-
Sahu, R.P.1
Zhang, R.2
Batra, S.3
Shi, Y.4
Srivastava, S.K.5
-
24
-
-
77956218104
-
Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells
-
Xiao, D., Powolny, A. A., Moura, M. B., Kelley, E. E., Bommareddy, A., Kim, S. H., et al. (2010). Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells. J Biological Chem, 285, 26558-26569.
-
(2010)
J Biological Chem
, vol.285
, pp. 26558-26569
-
-
Xiao, D.1
Powolny, A.A.2
Moura, M.B.3
Kelley, E.E.4
Bommareddy, A.5
Kim, S.H.6
Hahm, E.R.7
Normolle, D.8
van Houten, B.9
Singh, S.V.10
-
25
-
-
79251567380
-
Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells
-
Mi, L., Gan, N., & Chung, F. L. (2011). Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells. Carcinogenesis, 32, 216-223.
-
(2011)
Carcinogenesis
, vol.32
, pp. 216-223
-
-
Mi, L.1
Gan, N.2
Chung, F.L.3
-
26
-
-
80052857167
-
Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells
-
Ait-Mohamed, O., Battisti, V., Joliot, V., Fritsch, L., Pontis, J., Medjkane, S., et al. (2011). Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells. Plos One, 6, e24537.
-
(2011)
Plos One
, vol.6
-
-
Ait-Mohamed, O.1
Battisti, V.2
Joliot, V.3
Fritsch, L.4
Pontis, J.5
Medjkane, S.6
Redeuilh, C.7
Lamouri, A.8
Fahy, C.9
Rholam, M.10
-
27
-
-
84863044558
-
Alpha-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth
-
Johnson, J. J., Petiwala, S. M., Syed, D. N., Rasmussen, J. T., Adhami, V. M., Siddiqui, I. A., et al. (2012). Alpha-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth. Carcinogenesis, 33, 413-419.
-
(2012)
Carcinogenesis
, vol.33
, pp. 413-419
-
-
Johnson, J.J.1
Petiwala, S.M.2
Syed, D.N.3
Rasmussen, J.T.4
Adhami, V.M.5
Siddiqui, I.A.6
Kohl, A.M.7
Mukhtar, H.8
-
28
-
-
84863011392
-
Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases
-
Thakur, V. S., Gupta, K., & Gupta, S. (2012). Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases. Carcinogenesis, 33, 377-384.
-
(2012)
Carcinogenesis
, vol.33
, pp. 377-384
-
-
Thakur, V.S.1
Gupta, K.2
Gupta, S.3
-
29
-
-
70449107252
-
Redox-directed cancer therapeutics: molecular mechanisms and opportunities
-
Wondrak, G. T. (2009). Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxid Redox Signal, 11, 3013-3069.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 3013-3069
-
-
Wondrak, G.T.1
-
30
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
-
Trachootham, D., Alexandre, J., & Huang, P. (2009). Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov, 8, 579-591.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 579-591
-
-
Trachootham, D.1
Alexandre, J.2
Huang, P.3
-
31
-
-
27844445642
-
Perturbations of the AKT signaling pathway in human cancer
-
Altomare, D. A., & Testa, J. R. (2005). Perturbations of the AKT signaling pathway in human cancer. Oncogene, 24, 7455-7464.
-
(2005)
Oncogene
, vol.24
, pp. 7455-7464
-
-
Altomare, D.A.1
Testa, J.R.2
-
32
-
-
84984541581
-
Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells
-
Chen, K. F., Chen, H. L., Tai, W. T., Feng, W. C., Hsu, C. H., Chen, P. J., et al. (2011). Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells. J Pharmacol Exp Ther, 337, 155-161.
-
(2011)
J Pharmacol Exp Ther
, vol.337
, pp. 155-161
-
-
Chen, K.F.1
Chen, H.L.2
Tai, W.T.3
Feng, W.C.4
Hsu, C.H.5
Chen, P.J.6
Cheng, A.L.7
-
33
-
-
77953411708
-
Activated phosphoinositide 3-kinase/AKT signaling confers resistance to trastuzumab but not lapatinib
-
O'Brien, N. A., Browne, B. C., Chow, L., Wang, Y., Ginther, C., Arboleda, J., et al. (2010). Activated phosphoinositide 3-kinase/AKT signaling confers resistance to trastuzumab but not lapatinib. Mol Cancer Ther, 9, 1489-1502.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1489-1502
-
-
O'Brien, N.A.1
Browne, B.C.2
Chow, L.3
Wang, Y.4
Ginther, C.5
Arboleda, J.6
Duffy, M.J.7
Crown, J.8
O'Donovan, N.9
Slamon, D.J.10
-
34
-
-
65949086609
-
PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR
-
Sos, M. L., Koker, M., Weir, B. A., Heynck, S., Rabinovsky, R., Zander, T., et al. (2009). PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. Cancer Res, 69, 3256-3261.
-
(2009)
Cancer Res
, vol.69
, pp. 3256-3261
-
-
Sos, M.L.1
Koker, M.2
Weir, B.A.3
Heynck, S.4
Rabinovsky, R.5
Zander, T.6
Seeger, J.M.7
Weiss, J.8
Fischer, F.9
Frommolt, P.10
-
35
-
-
79951722712
-
Inhibiting the PI3 K/Akt pathway reversed progestin resistance in endometrial cancer
-
Gu, C., Zhang, Z., Yu, Y., Liu, Y., Zhao, F., Yin, L., et al. (2011). Inhibiting the PI3 K/Akt pathway reversed progestin resistance in endometrial cancer. Cancer Sci, 102, 557-564.
-
(2011)
Cancer Sci
, vol.102
, pp. 557-564
-
-
Gu, C.1
Zhang, Z.2
Yu, Y.3
Liu, Y.4
Zhao, F.5
Yin, L.6
Feng, Y.7
Chen, X.8
-
36
-
-
78650842574
-
Mechanisms underlying resistance to cetuximab in the HNSCC cell line: role of AKT inhibition in bypassing this resistance
-
Rebucci, M., Peixoto, P., Dewitte, A., Wattez, N., De Nuncques, M. A., Rezvoy, N., et al. (2011). Mechanisms underlying resistance to cetuximab in the HNSCC cell line: role of AKT inhibition in bypassing this resistance. Int J Oncol, 38, 189-200.
-
(2011)
Int J Oncol
, vol.38
, pp. 189-200
-
-
Rebucci, M.1
Peixoto, P.2
Dewitte, A.3
Wattez, N.4
De Nuncques, M.A.5
Rezvoy, N.6
Vautravers-Dewas, C.7
Buisine, M.P.8
Guerin, E.9
Peyrat, J.P.10
-
37
-
-
70449494636
-
Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2
-
Gupta, M., Ansell, S. M., Novak, A. J., Kumar, S., Kaufmann, S. H., & Witzig, T. E. (2009). Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2. Blood, 114, 2926-2935.
-
(2009)
Blood
, vol.114
, pp. 2926-2935
-
-
Gupta, M.1
Ansell, S.M.2
Novak, A.J.3
Kumar, S.4
Kaufmann, S.H.5
Witzig, T.E.6
-
38
-
-
76249121230
-
BCR-ABL-independent and RAS/MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4
-
Suzuki, M., Abe, A., Imagama, S., Nomura, Y., Tanizaki, R., Minami, Y., et al. (2010). BCR-ABL-independent and RAS/MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4. Eur J Haematol, 84, 229-238.
-
(2010)
Eur J Haematol
, vol.84
, pp. 229-238
-
-
Suzuki, M.1
Abe, A.2
Imagama, S.3
Nomura, Y.4
Tanizaki, R.5
Minami, Y.6
Hayakawa, F.7
Ito, Y.8
Katsumi, A.9
Yamamoto, K.10
-
39
-
-
61349152467
-
Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells
-
Guo, X., Ma, N., Wang, J., Song, J., Bu, X., Cheng, Y., et al. (2008). Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells. BMC Cancer, 8, 375.
-
(2008)
BMC Cancer
, vol.8
, pp. 375
-
-
Guo, X.1
Ma, N.2
Wang, J.3
Song, J.4
Bu, X.5
Cheng, Y.6
Sun, K.7
Xiong, H.8
Jiang, G.9
Zhang, B.10
-
40
-
-
48349094564
-
Lower level of MAPK expression is associated with anthracycline resistance and decreased survival in patients with hormone receptor negative breast cancer
-
Derin, D., Eralp, Y., Ozluk, Y., Yavuz, E., Guney, N., Saip, P., et al. (2008). Lower level of MAPK expression is associated with anthracycline resistance and decreased survival in patients with hormone receptor negative breast cancer. Cancer Investig, 26, 671-679.
-
(2008)
Cancer Investig
, vol.26
, pp. 671-679
-
-
Derin, D.1
Eralp, Y.2
Ozluk, Y.3
Yavuz, E.4
Guney, N.5
Saip, P.6
Igci, A.7
Ozmen, V.8
Kucucuk, S.9
Aslay, I.10
-
41
-
-
52949113842
-
Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling
-
Normanno, N., Campiglio, M., Maiello, M. R., De Luca, A., Mancino, M., Gallo, M., et al. (2008). Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling. Breast Cancer Res Treat, 112, 25-33.
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 25-33
-
-
Normanno, N.1
Campiglio, M.2
Maiello, M.R.3
De Luca, A.4
Mancino, M.5
Gallo, M.6
D'Alessio, A.7
Menard, S.8
-
42
-
-
33645652766
-
The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib
-
Normanno, N., De Luca, A., Maiello, M. R., Campiglio, M., Napolitano, M., Mancino, M., et al. (2006). The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib. J Cell Physiol, 207, 420-427.
-
(2006)
J Cell Physiol
, vol.207
, pp. 420-427
-
-
Normanno, N.1
De Luca, A.2
Maiello, M.R.3
Campiglio, M.4
Napolitano, M.5
Mancino, M.6
Carotenuto, A.7
Viglietto, G.8
Menard, S.9
-
43
-
-
73549115638
-
Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3 K/Akt signaling pathways
-
Ghayad, S. E., Vendrell, J. A., Larbi, S. B., Dumontet, C., Bieche, I., & Cohen, P. A. (2010). Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3 K/Akt signaling pathways. Int J Cancer, 126, 545-562.
-
(2010)
Int J Cancer
, vol.126
, pp. 545-562
-
-
Ghayad, S.E.1
Vendrell, J.A.2
Larbi, S.B.3
Dumontet, C.4
Bieche, I.5
Cohen, P.A.6
-
44
-
-
79551595325
-
Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells
-
Jiao, J. W., & Wen, F. (2011). Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells. Oncol Rep, 25, 781-788.
-
(2011)
Oncol Rep
, vol.25
, pp. 781-788
-
-
Jiao, J.W.1
Wen, F.2
-
45
-
-
79551559585
-
Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma
-
Paillas, S., Boissiere, F., Bibeau, F., Denouel, A., Mollevi, C., Causse, A., et al. (2010). Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma. Cancer Res, 71, 1041-1049.
-
(2010)
Cancer Res
, vol.71
, pp. 1041-1049
-
-
Paillas, S.1
Boissiere, F.2
Bibeau, F.3
Denouel, A.4
Mollevi, C.5
Causse, A.6
Denis, V.7
Vezzio-Vie, N.8
Marzi, L.9
Cortijo, C.10
-
46
-
-
78650934534
-
Integrated quantitative analysis of the phosphoproteome and transcriptome in tamoxifen-resistant breast cancer
-
Oyama, M., Nagashima, T., Suzuki, T., Kozuka-Hata, H., Yumoto, N., Shiraishi, Y., et al. (2011). Integrated quantitative analysis of the phosphoproteome and transcriptome in tamoxifen-resistant breast cancer. J Biological Chem, 286, 818-829.
-
(2011)
J Biological Chem
, vol.286
, pp. 818-829
-
-
Oyama, M.1
Nagashima, T.2
Suzuki, T.3
Kozuka-Hata, H.4
Yumoto, N.5
Shiraishi, Y.6
Ikeda, K.7
Kuroki, Y.8
Gotoh, N.9
Ishida, T.10
-
47
-
-
79957572444
-
Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells
-
Bachmeier, B., Fichtner, I., Killian, P. H., Kronski, E., Pfeffer, U., & Efferth, T. (2011). Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells. Plos One, 6, e20550.
-
(2011)
Plos One
, vol.6
-
-
Bachmeier, B.1
Fichtner, I.2
Killian, P.H.3
Kronski, E.4
Pfeffer, U.5
Efferth, T.6
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