-
1
-
-
0024973841
-
The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo
-
Weigel D, Jurgens G, Kuttner F, Seifert E, Jackle H. The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo. Cell 1989; 57: 645-658.
-
(1989)
Cell
, vol.57
, pp. 645-658
-
-
Weigel, D.1
Jurgens, G.2
Kuttner, F.3
Seifert, E.4
Jackle, H.5
-
2
-
-
62549108593
-
The evolution of Fox genes and their role in development and disease
-
Hannenhalli S, Kaestner KH. The evolution of Fox genes and their role in development and disease. Nat Rev Genet 2009; 10: 233-240.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 233-240
-
-
Hannenhalli, S.1
Kaestner, K.H.2
-
3
-
-
0027959091
-
Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family
-
Parry P, Wei Y, Evans G. Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family. Genes Chromosomes Cancer 1994; 11: 79-84.
-
(1994)
Genes Chromosomes Cancer
, vol.11
, pp. 79-84
-
-
Parry, P.1
Wei, Y.2
Evans, G.3
-
4
-
-
0031031378
-
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)
-
Borkhardt A, Repp R, Haas OA, et al. Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23). Oncogene 1997; 14: 195-202.
-
(1997)
Oncogene
, vol.14
, pp. 195-202
-
-
Borkhardt, A.1
Repp, R.2
Haas, O.A.3
-
5
-
-
0032518255
-
Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily
-
Anderson MJ, Viars CS, Czekay S, Cavenee WK, Arden KC. Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. Genomics 1998; 47: 187-199.
-
(1998)
Genomics
, vol.47
, pp. 187-199
-
-
Anderson, M.J.1
Viars, C.S.2
Czekay, S.3
Cavenee, W.K.4
Arden, K.C.5
-
6
-
-
0141481091
-
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics
-
Jacobs FM, van der Heide LP, Wijchers PJ, Burbach JP, Hoekman MF, Smidt MP. FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics. J Biol Chem 2003; 278: 35959-35967.
-
(2003)
J Biol Chem
, vol.278
, pp. 35959-35967
-
-
Jacobs, F.M.1
van der Heide, L.P.2
Wijchers, P.J.3
Burbach, J.P.4
Hoekman, M.F.5
Smidt, M.P.6
-
7
-
-
11144294668
-
From worm to human: Bioinformatics approaches to identify FOXO target genes
-
Xuan Z, Zhang MQ. From worm to human: bioinformatics approaches to identify FOXO target genes. Mech Ageing Dev 2005; 126: 209-215.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 209-215
-
-
Xuan, Z.1
Zhang, M.Q.2
-
8
-
-
0034661826
-
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
-
Furuyama T, Nakazawa T, Nakano I, Mori N. Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem J 2000; 349: 629-634.
-
(2000)
Biochem J
, vol.349
, pp. 629-634
-
-
Furuyama, T.1
Nakazawa, T.2
Nakano, I.3
Mori, N.4
-
9
-
-
0036893049
-
Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a)
-
Liu PP, Chen YC, Li C, et al. Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a). Proteins 2002; 49: 543-553.
-
(2002)
Proteins
, vol.49
, pp. 543-553
-
-
Liu, P.P.1
Chen, Y.C.2
Li, C.3
-
10
-
-
0035918516
-
Solution structure of the DNA binding domain of the human forkhead transcription factor AFX (FOXO4)
-
Weigelt J, Climent I, Dahlman-Wright K, Wikstrom M. Solution structure of the DNA binding domain of the human forkhead transcription factor AFX (FOXO4). Biochemistry 2001; 40: 5861-5869.
-
(2001)
Biochemistry
, vol.40
, pp. 5861-5869
-
-
Weigelt, J.1
Climent, I.2
Dahlman-Wright, K.3
Wikstrom, M.4
-
11
-
-
36749079110
-
Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification
-
Tsai KL, Sun YJ, Huang CY, Yang JY, Hung MC, Hsiao CD. Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification. Nucleic Acids Res 2007; 35: 6984-6994.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 6984-6994
-
-
Tsai, K.L.1
Sun, Y.J.2
Huang, C.Y.3
Yang, J.Y.4
Hung, M.C.5
Hsiao, C.D.6
-
12
-
-
50849130900
-
Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification
-
Brent MM, Anand R, Marmorstein R. Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification. Structure 2008; 16: 1407-1416.
-
(2008)
Structure
, vol.16
, pp. 1407-1416
-
-
Brent, M.M.1
Anand, R.2
Marmorstein, R.3
-
13
-
-
0027270989
-
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
-
Clark KL, Halay ED, Lai E, Burley SK. Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 1993; 364: 412-420.
-
(1993)
Nature
, vol.364
, pp. 412-420
-
-
Clark, K.L.1
Halay, E.D.2
Lai, E.3
Burley, S.K.4
-
14
-
-
37249054901
-
Chromatin opening and stable perturbation of core histone: DNA contacts by FoxO1
-
Hatta M, Cirillo LA. Chromatin opening and stable perturbation of core histone: DNA contacts by FoxO1. J Biol Chem 2007; 282: 35583-35593.
-
(2007)
J Biol Chem
, vol.282
, pp. 35583-35593
-
-
Hatta, M.1
Cirillo, L.A.2
-
15
-
-
0027402969
-
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
-
1993 Mar 18
-
Ramakrishnan V, Finch JT, Graziano V, Lee PL, Sweet RM. Crystal structure of globular domain of histone H5 and its implications for nucleosome binding. Nature. 1993 Mar 18;362(6417):219-223.
-
Nature
, vol.362
, Issue.6417
, pp. 219-223
-
-
Ramakrishnan, V.1
Finch, J.T.2
Graziano, V.3
Lee, P.L.4
Sweet, R.M.5
-
16
-
-
0033388099
-
An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA
-
Cirillo LA, Zaret KS. An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA. Mol Cell 1999; 4: 961-969.
-
(1999)
Mol Cell
, vol.4
, pp. 961-969
-
-
Cirillo, L.A.1
Zaret, K.S.2
-
17
-
-
33645227508
-
The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure
-
Yan J, Xu L, Crawford G, Wang Z, Burgess SM. The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure. Mol Cell Biol 2006; 26: 155-168.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 155-168
-
-
Yan, J.1
Xu, L.2
Crawford, G.3
Wang, Z.4
Burgess, S.M.5
-
18
-
-
0036184236
-
Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4
-
Cirillo LA, Lin FR, Cuesta I, Friedman D, Jarnik M, Zaret KS. Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. Mol Cell 2002; 9: 279-289.
-
(2002)
Mol Cell
, vol.9
, pp. 279-289
-
-
Cirillo, L.A.1
Lin, F.R.2
Cuesta, I.3
Friedman, D.4
Jarnik, M.5
Zaret, K.S.6
-
19
-
-
23144444979
-
Protein structure prediction servers at University College London
-
Bryson K, McGuffin LJ, Marsden RL, Ward JJ, Sodhi JS, Jones DT. Protein structure prediction servers at University College London. Nucleic Acids Res 2005; 33: W36-W38.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 36-38
-
-
Bryson, K.1
McGuffin, L.J.2
Marsden, R.L.3
Ward, J.J.4
Sodhi, J.S.5
Jones, D.T.6
-
20
-
-
0037438589
-
Common mechanism for oncogenic activation of MLL by forkhead family proteins
-
So CW, Cleary ML. Common mechanism for oncogenic activation of MLL by forkhead family proteins. Blood 2003; 101: 633-639.
-
(2003)
Blood
, vol.101
, pp. 633-639
-
-
So, C.W.1
Cleary, M.L.2
-
21
-
-
0036723650
-
MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function
-
So CW, Cleary ML. MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function. Mol Cell Biol 2002; 22: 6542-6552.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6542-6552
-
-
So, C.W.1
Cleary, M.L.2
-
22
-
-
34247267098
-
Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding
-
Boura E, Silhan J, Herman P, et al. Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding. J Biol Chem 2007; 282: 8265-8275.
-
(2007)
J Biol Chem
, vol.282
, pp. 8265-8275
-
-
Boura, E.1
Silhan, J.2
Herman, P.3
-
23
-
-
84954358441
-
Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53
-
Wang F, Marshall CB, Yamamoto K, et al. Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53. J Mol Biol 2008; 384: 590-603.
-
(2008)
J Mol Biol
, vol.384
, pp. 590-603
-
-
Wang, F.1
Marshall, C.B.2
Yamamoto, K.3
-
24
-
-
73649087930
-
Synergistic Interplay between Promoter Recognition and CBP/p300 Coactivator Recruitment by FOXO3a
-
Wang F, Marshall CB, Li GY, Yamamoto K, Mak TW, Ikura M. Synergistic Interplay between Promoter Recognition and CBP/p300 Coactivator Recruitment by FOXO3a. ACS Chem Biol 2009; 4: 1017-1027.
-
(2009)
ACS Chem Biol
, vol.4
, pp. 1017-1027
-
-
Wang, F.1
Marshall, C.B.2
Li, G.Y.3
Yamamoto, K.4
Mak, T.W.5
Ikura, M.6
-
26
-
-
0038003956
-
Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty
-
Burgering BM, Medema RH. Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty. J Leukoc Biol 2003; 73: 689-701.
-
(2003)
J Leukoc Biol
, vol.73
, pp. 689-701
-
-
Burgering, B.M.1
Medema, R.H.2
-
27
-
-
1542267804
-
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
-
Hosaka T, Biggs WH, 3rd, Tieu D, et al. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci USA 2004; 101: 2975-2980.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2975-2980
-
-
Hosaka, T.1
Biggs, W.H.2
Tieu, D.3
-
28
-
-
4544227785
-
Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice
-
Furuyama T, Kitayama K, Shimoda Y, et al. Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice. J Biol Chem 2004; 279: 34741-34749.
-
(2004)
J Biol Chem
, vol.279
, pp. 34741-34749
-
-
Furuyama, T.1
Kitayama, K.2
Shimoda, Y.3
-
29
-
-
0038152845
-
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a
-
Castrillon DH, Miao L, Kollipara R, Horner JW, DePinho RA. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science 2003; 301: 215-218.
-
(2003)
Science
, vol.301
, pp. 215-218
-
-
Castrillon, D.H.1
Miao, L.2
Kollipara, R.3
Horner, J.W.4
Depinho, R.A.5
-
30
-
-
4143129696
-
Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a
-
Lin L, Hron JD, Peng SL. Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a. Immunity 2004; 21: 203-213.
-
(2004)
Immunity
, vol.21
, pp. 203-213
-
-
Lin, L.1
Hron, J.D.2
Peng, S.L.3
-
31
-
-
0036651790
-
A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR
-
Ramaswamy S, Nakamura N, Sansal I, Bergeron L, Sellers WR. A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR. Cancer Cell 2002; 2: 81-91.
-
(2002)
Cancer Cell
, vol.2
, pp. 81-91
-
-
Ramaswamy, S.1
Nakamura, N.2
Sansal, I.3
Bergeron, L.4
Sellers, W.R.5
-
32
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs WH, 3rd, Meisenhelder J, Hunter T, Cavenee WK, Arden KC. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci USA 1999; 96: 7421-7426.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7421-7426
-
-
Biggs, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
33
-
-
30444442827
-
Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain
-
Hoekman MF, Jacobs FM, Smidt MP, Burbach JP. Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr Patterns 2006; 6: 134-140.
-
(2006)
Gene Expr Patterns
, vol.6
, pp. 134-140
-
-
Hoekman, M.F.1
Jacobs, F.M.2
Smidt, M.P.3
Burbach, J.P.4
-
34
-
-
36448968532
-
FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
-
Zhao J, Brault JJ, Schild A, et al. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 2007; 6: 472-483.
-
(2007)
Cell Metab
, vol.6
, pp. 472-483
-
-
Zhao, J.1
Brault, J.J.2
Schild, A.3
-
35
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy CT, McCarroll SA, Bargmann CI, et al. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 2003; 424: 277-283.
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
-
36
-
-
36448940798
-
FoxO3 controls autophagy in skeletal muscle in vivo
-
Mammucari C, Milan G, Romanello V, et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 2007; 6: 458-471.
-
(2007)
Cell Metab
, vol.6
, pp. 458-471
-
-
Mammucari, C.1
Milan, G.2
Romanello, V.3
-
37
-
-
0037466652
-
DAF-16 target genes that control C. elegans life-span and metabolism
-
Lee SS, Kennedy S, Tolonen AC, Ruvkun G. DAF-16 target genes that control C. elegans life-span and metabolism. Science 2003; 300: 644-647.
-
(2003)
Science
, vol.300
, pp. 644-647
-
-
Lee, S.S.1
Kennedy, S.2
Tolonen, A.C.3
Ruvkun, G.4
-
38
-
-
0037134040
-
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
-
Tran H, Brunet A, Grenier JM, et al. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 2002; 296: 530-534.
-
(2002)
Science
, vol.296
, pp. 530-534
-
-
Tran, H.1
Brunet, A.2
Grenier, J.M.3
-
39
-
-
0037192473
-
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
-
Nemoto S, Finkel T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 2002; 295: 2450-2452.
-
(2002)
Science
, vol.295
, pp. 2450-2452
-
-
Nemoto, S.1
Finkel, T.2
-
40
-
-
0034643331
-
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
-
Medema RH, Kops GJ, Bos JL, Burgering BM. AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 2000; 404: 782-787.
-
(2000)
Nature
, vol.404
, pp. 782-787
-
-
Medema, R.H.1
Kops, G.J.2
Bos, J.L.3
Burgering, B.M.4
-
41
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
Kops GJ, Dansen TB, Polderman PE, et al. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 2002; 419: 316-321.
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
-
42
-
-
0034609737
-
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
-
Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 2000; 10: 1201-1214.
-
(2000)
Curr Biol
, vol.10
, pp. 1201-1214
-
-
Dijkers, P.F.1
Medema, R.H.2
Lammers, J.W.3
Koenderman, L.4
Coffer, P.J.5
-
43
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999; 96: 857-868.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
-
44
-
-
70350518100
-
Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases
-
Link W, Oyarzabal J, Serelde BG, et al. Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases. J Biol Chem 2009; 284: 28392-28400.
-
(2009)
J Biol Chem
, vol.284
, pp. 28392-28400
-
-
Link, W.1
Oyarzabal, J.2
Serelde, B.G.3
-
45
-
-
11144357466
-
IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
Hu MC, Lee DF, Xia W, et al. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 2004; 117: 225-237.
-
(2004)
Cell
, vol.117
, pp. 225-237
-
-
Mc, H.1
Lee, D.F.2
Xia, W.3
-
46
-
-
16244415180
-
Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity
-
Yang H, Zhao R, Yang HY, Lee MH. Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity. Oncogene 2005; 24: 1924-1935.
-
(2005)
Oncogene
, vol.24
, pp. 1924-1935
-
-
Yang, H.1
Zhao, R.2
Yang, H.Y.3
Lee, M.H.4
-
47
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004; 303: 2011-2015.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
-
48
-
-
1642332084
-
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
-
Seoane J, Le HV, Shen L, Anderson SA, Massague J. Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell 2004; 117: 211-223.
-
(2004)
Cell
, vol.117
, pp. 211-223
-
-
Seoane, J.1
Le, H.V.2
Shen, L.3
Anderson, S.A.4
Massague, J.5
-
49
-
-
18844382368
-
Functional interaction between beta-catenin and FOXO in oxidative stress signaling
-
Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM, Korswagen HC. Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science 2005; 308: 1181-1184.
-
(2005)
Science
, vol.308
, pp. 1181-1184
-
-
Essers, M.A.1
de Vries-Smits, L.M.2
Barker, N.3
Polderman, P.E.4
Burgering, B.M.5
Korswagen, H.C.6
-
51
-
-
4143050290
-
The interaction between FOXO and SIRT1: Tipping the balance towards survival
-
Giannakou ME, Partridge L. The interaction between FOXO and SIRT1: tipping the balance towards survival. Trends Cell Biol 2004; 14: 408-412.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 408-412
-
-
Giannakou, M.E.1
Partridge, L.2
-
52
-
-
2942563805
-
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
-
Hwangbo DS, Gershman B, Tu MP, Palmer M, Tatar M. Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 2004; 429: 562-566.
-
(2004)
Nature
, vol.429
, pp. 562-566
-
-
Hwangbo, D.S.1
Gershman, B.2
Tu, M.P.3
Palmer, M.4
Tatar, M.5
-
53
-
-
0035846604
-
Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
-
Henderson ST, Johnson TE. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol 2001; 11: 1975-1980.
-
(2001)
Curr Biol
, vol.11
, pp. 1975-1980
-
-
Henderson, S.T.1
Johnson, T.E.2
-
54
-
-
0030657540
-
Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
Lin K, Dorman JB, Rodan A, Kenyon C. daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 1997; 278: 1319-1322.
-
(1997)
Science
, vol.278
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
55
-
-
0030659557
-
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
Ogg S, Paradis S, Gottlieb S, et al. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 1997; 389: 994-999.
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
-
56
-
-
62449083712
-
Association of FOXO3A variation with human longevity confirmed in German centenarians
-
Flachsbart F, Caliebe A, Kleindorp R, et al. Association of FOXO3A variation with human longevity confirmed in German centenarians. Proc Natl Acad Sci USA 2009; 106: 2700-2705.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2700-2705
-
-
Flachsbart, F.1
Caliebe, A.2
Kleindorp, R.3
-
57
-
-
52949122885
-
FOXO3A genotype is strongly associated with human longevity
-
Willcox BJ, Donlon TA, He Q, et al. FOXO3A genotype is strongly associated with human longevity. Proc Natl Acad Sci USA 2008; 105:13987-13992.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13987-13992
-
-
Willcox, B.J.1
Donlon, T.A.2
He, Q.3
-
58
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova Z, Kollipara R, Huntly BJ, et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 2007; 128: 325-339.
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
-
59
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto K, Araki KY, Naka K, et al. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 2007; 1: 101-112.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 101-112
-
-
Miyamoto, K.1
Araki, K.Y.2
Naka, K.3
-
60
-
-
1642580499
-
FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1
-
Bakker WJ, Blazquez-Domingo M, Kolbus A, et al. FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol 2004; 164: 175-184.
-
(2004)
J Cell Biol
, vol.164
, pp. 175-184
-
-
Bakker, W.J.1
Blazquez-Domingo, M.2
Kolbus, A.3
-
61
-
-
34250214921
-
Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis
-
Dejana E, Taddei A, Randi AM. Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis. Biochim Biophys Acta 2007; 1775: 298-312.
-
(2007)
Biochim Biophys Acta
, vol.1775
, pp. 298-312
-
-
Dejana, E.1
Taddei, A.2
Randi, A.M.3
-
62
-
-
0042477748
-
Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors
-
Hribal ML, Nakae J, Kitamura T, Shutter JR, Accili D. Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors. J Cell Biol 2003; 162: 535-541.
-
(2003)
J Cell Biol
, vol.162
, pp. 535-541
-
-
Hribal, M.L.1
Nakae, J.2
Kitamura, T.3
Shutter, J.R.4
Accili, D.5
-
63
-
-
0037237279
-
The forkhead transcription factor Foxo1 regulates adipocyte differentiation
-
Nakae J, Kitamura T, Kitamura Y, Biggs WH, 3rd, Arden KC, Accili D. The forkhead transcription factor Foxo1 regulates adipocyte differentiation. Dev Cell 2003; 4: 119-129.
-
(2003)
Dev Cell
, vol.4
, pp. 119-129
-
-
Nakae, J.1
Kitamura, T.2
Kitamura, Y.3
Biggs, W.H.4
Arden, K.C.5
Accili, D.6
-
64
-
-
34548349302
-
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver
-
Matsumoto M, Pocai A, Rossetti L, Depinho RA, Accili D. Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver. Cell Metab 2007; 6: 208-216.
-
(2007)
Cell Metab
, vol.6
, pp. 208-216
-
-
Matsumoto, M.1
Pocai, A.2
Rossetti, L.3
Depinho, R.A.4
Accili, D.5
-
65
-
-
33748312093
-
Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism
-
Matsumoto M, Han S, Kitamura T, Accili D. Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism. J Clin Invest 2006; 116: 2464-2472.
-
(2006)
J Clin Invest
, vol.116
, pp. 2464-2472
-
-
Matsumoto, M.1
Han, S.2
Kitamura, T.3
Accili, D.4
-
66
-
-
33745576798
-
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
-
Kim MS, Pak YK, Jang PG, et al. Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis. Nat Neurosci 2006; 9: 901-906.
-
(2006)
Nat Neurosci
, vol.9
, pp. 901-906
-
-
Kim, M.S.1
Pak, Y.K.2
Jang, P.G.3
-
67
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
Puigserver P, Rhee J, Donovan J, et al. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 2003; 423: 550-555.
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
-
68
-
-
33646590947
-
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake
-
Kitamura T, Feng Y, Kitamura YI, et al. Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake. Nat Med 2006; 12: 534-540.
-
(2006)
Nat Med
, vol.12
, pp. 534-540
-
-
Kitamura, T.1
Feng, Y.2
Kitamura, Y.I.3
-
70
-
-
0034680839
-
Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity
-
Schmoll D, Walker KS, Alessi DR, et al. Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity. J Biol Chem 2000; 275: 36324-36333.
-
(2000)
J Biol Chem
, vol.275
, pp. 36324-36333
-
-
Schmoll, D.1
Walker, K.S.2
Alessi, D.R.3
-
71
-
-
0036787607
-
Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
-
Nakae J, Biggs WH, 3rd, Kitamura T, et al. Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet. 2002; 32: 245-253.
-
(2002)
Nat Genet
, vol.32
, pp. 245-253
-
-
Nakae, J.1
Biggs, W.H.2
Kitamura, T.3
-
72
-
-
0034730660
-
Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins
-
Hall RK, Yamasaki T, Kucera T, Waltner-Law M, O'Brien R, Granner DK. Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins. J Biol Chem 2000; 275: 30169-30175.
-
(2000)
J Biol Chem
, vol.275
, pp. 30169-30175
-
-
Hall, R.K.1
Yamasaki, T.2
Kucera, T.3
Waltner-Law, M.4
O'Brien, R.5
Granner, D.K.6
-
73
-
-
38049148308
-
FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases
-
Ni YG, Wang N, Cao DJ, et al. FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases. Proc Natl Acad Sci USA 2007; 104: 20517-20522.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20517-20522
-
-
Ni, Y.G.1
Wang, N.2
Cao, D.J.3
-
74
-
-
34848850156
-
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
-
Greer EL, Dowlatshahi D, Banko MR, et al. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr Biol 2007; 17: 1646-1656.
-
(2007)
Curr Biol
, vol.17
, pp. 1646-1656
-
-
Greer, E.L.1
Dowlatshahi, D.2
Banko, M.R.3
-
75
-
-
0030813398
-
Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 1997; 277: 942-946.
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
-
76
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993; 366: 461-464.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
77
-
-
0035958853
-
Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions
-
Zhao HH, Herrera RE, Coronado-Heinsohn E, et al. Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions. J Biol Chem 2001; 276: 27907-27912.
-
(2001)
J Biol Chem
, vol.276
, pp. 27907-27912
-
-
Zhao, H.H.1
Herrera, R.E.2
Coronado-Heinsohn, E.3
-
78
-
-
0038645860
-
Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor
-
Hirota K, Daitoku H, Matsuzaki H, et al. Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor. J Biol Chem 2003; 278: 13056-13060.
-
(2003)
J Biol Chem
, vol.278
, pp. 13056-13060
-
-
Hirota, K.1
Daitoku, H.2
Matsuzaki, H.3
-
79
-
-
0030695445
-
The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism
-
Stoffel M, Duncan SA. The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci USA 1997; 94: 13209-13214.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13209-13214
-
-
Stoffel, M.1
Duncan, S.A.2
-
80
-
-
0025690311
-
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
-
Sladek FM, Zhong WM, Lai E, Darnell JE, Jr. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev 1990; 4: 2353-2365.
-
(1990)
Genes Dev
, vol.4
, pp. 2353-2365
-
-
Sladek, F.M.1
Zhong, W.M.2
Lai, E.3
Darnell Jr., J.E.4
-
81
-
-
0035141324
-
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
-
Hayhurst GP, Lee YH, Lambert G, Ward JM, Gonzalez FJ. Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol Cell Biol 2001; 21: 1393-1403.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1393-1403
-
-
Hayhurst, G.P.1
Lee, Y.H.2
Lambert, G.3
Ward, J.M.4
Gonzalez, F.J.5
-
82
-
-
0030042979
-
Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes
-
Drewes T, Senkel S, Holewa B, Ryffel GU. Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes. Mol Cell Biol 1996; 16: 925-931.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 925-931
-
-
Drewes, T.1
Senkel, S.2
Holewa, B.3
Ryffel, G.U.4
-
83
-
-
0027362622
-
Functional characterization of the L-type pyruvate kinase gene glucose response complex
-
Diaz Guerra MJ, Bergot MO, Martinez A, Cuif MH, Kahn A, Raymondjean M. Functional characterization of the L-type pyruvate kinase gene glucose response complex. Mol Cell Biol 1993; 13: 7725-7733.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7725-7733
-
-
Diaz, G.M.J.1
Bergot, M.O.2
Martinez, A.3
Cuif, M.H.4
Kahn, A.5
Raymondjean, M.6
-
84
-
-
57749116021
-
A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding
-
Hirota K, Sakamaki J, Ishida J, et al. A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding. J Biol Chem 2008; 283: 32432-32441.
-
(2008)
J Biol Chem
, vol.283
, pp. 32432-32441
-
-
Hirota, K.1
Sakamaki, J.2
Ishida, J.3
-
85
-
-
0038645860
-
Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor
-
Hirota K, Daitoku H, Matsuzaki H, et al. Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor. J Biol Chem 2003; 278: 13056-13060.
-
(2003)
J Biol Chem
, vol.278
, pp. 13056-13060
-
-
Hirota, K.1
Daitoku, H.2
Matsuzaki, H.3
-
86
-
-
0042232315
-
PGC-1beta in the regulation of hepatic glucose and energy metabolism
-
Lin J, Tarr PT, Yang R, et al. PGC-1beta in the regulation of hepatic glucose and energy metabolism. J Biol Chem 2003; 278: 30843-30848.
-
(2003)
J Biol Chem
, vol.278
, pp. 30843-30848
-
-
Lin, J.1
Tarr, P.T.2
Yang, R.3
-
87
-
-
0036903174
-
Adaptations of skeletal muscle to exercise: Rapid increase in the transcriptional coactivator PGC-1
-
Baar K, Wende AR, Jones TE, et al. Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. Faseb J 2002; 16: 1879-1886.
-
(2002)
Faseb J
, vol.16
, pp. 1879-1886
-
-
Baar, K.1
Wende, A.R.2
Jones, T.E.3
-
88
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, Puigserver P, Andersson U, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999; 98: 115-124.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
-
89
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998; 92: 829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
90
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
Lin J, Wu PH, Tarr PT, et al. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 2004; 119: 121-135.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
-
91
-
-
10744227070
-
Control of pancreas and liver gene expression by HNF transcription factors
-
Odom DT, Zizlsperger N, Gordon DB, et al. Control of pancreas and liver gene expression by HNF transcription factors. Science 2004; 303:1378-1381.
-
(2004)
Science
, vol.303
, pp. 1378-1381
-
-
Odom, D.T.1
Zizlsperger, N.2
Gordon, D.B.3
-
92
-
-
0242349197
-
Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): Requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis
-
Rhee J, Inoue Y, Yoon JC, et al. Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc Natl Acad Sci USA 2003; 100: 4012-4017.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4012-4017
-
-
Rhee, J.1
Inoue, Y.2
Yoon, J.C.3
-
93
-
-
0037342151
-
Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR
-
Daitoku H, Yamagata K, Matsuzaki H, Hatta M, Fukamizu A. Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR. Diabetes 2003; 52: 642-649.
-
(2003)
Diabetes
, vol.52
, pp. 642-649
-
-
Daitoku, H.1
Yamagata, K.2
Matsuzaki, H.3
Hatta, M.4
Fukamizu, A.5
-
94
-
-
64149111641
-
A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose
-
Housley MP, Udeshi ND, Rodgers JT, et al. A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. J Biol Chem 2009; 284: 5148-5157.
-
(2009)
J Biol Chem
, vol.284
, pp. 5148-5157
-
-
Housley, M.P.1
Udeshi, N.D.2
Rodgers, J.T.3
-
95
-
-
34250740323
-
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator
-
Li X, Monks B, Ge Q, Birnbaum MJ. Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator. Nature 2007; 447: 1012-1016.
-
(2007)
Nature
, vol.447
, pp. 1012-1016
-
-
Li, X.1
Monks, B.2
Ge, Q.3
Birnbaum, M.J.4
-
96
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
Jager S, Handschin C, St-Pierre J, Spiegelman BM. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci USA 2007; 104: 12017-12022.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12017-12022
-
-
Jager, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
97
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005; 434: 113-118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
98
-
-
34247259630
-
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha
-
Gerhart-Hines Z, Rodgers JT, Bare O, et al. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. Embo J 2007; 26: 1913-1923.
-
(2007)
Embo J
, vol.26
, pp. 1913-1923
-
-
Gerhart-Hines, Z.1
Rodgers, J.T.2
Bare, O.3
-
99
-
-
70449122132
-
Foxo1 integrates insulin signaling with mitochondrial function in the liver
-
Cheng Z, Guo S, Copps K, et al. Foxo1 integrates insulin signaling with mitochondrial function in the liver. Nat Med 2009; 15: 1307-1311.
-
(2009)
Nat Med
, vol.15
, pp. 1307-1311
-
-
Cheng, Z.1
Guo, S.2
Copps, K.3
-
100
-
-
0037337666
-
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues
-
Schomburg L, Schweizer U, Holtmann B, Flohe L, Sendtner M, Kohrle J. Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. Biochem J 2003; 370: 397-402.
-
(2003)
Biochem J
, vol.370
, pp. 397-402
-
-
Schomburg, L.1
Schweizer, U.2
Holtmann, B.3
Flohe, L.4
Sendtner, M.5
Kohrle, J.6
-
101
-
-
0037515627
-
Deletion of selenoprotein P alters distribution of selenium in the mouse
-
Hill KE, Zhou J, McMahan WJ, et al. Deletion of selenoprotein P alters distribution of selenium in the mouse. J Biol Chem 2003; 278: 13640-13646.
-
(2003)
J Biol Chem
, vol.278
, pp. 13640-13646
-
-
Hill, K.E.1
Zhou, J.2
McMahan, W.J.3
-
102
-
-
36248988618
-
Stimulation of selenoprotein P promoter activity in hepatoma cells by FoxO1a transcription factor
-
Walter PL, Steinbrenner H, Barthel A, Klotz LO. Stimulation of selenoprotein P promoter activity in hepatoma cells by FoxO1a transcription factor. Biochem Biophys Res Commun 2008; 365: 316-321.
-
(2008)
Biochem Biophys Res Commun
, vol.365
, pp. 316-321
-
-
Walter, P.L.1
Steinbrenner, H.2
Barthel, A.3
Klotz, L.O.4
-
103
-
-
58149395124
-
Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors
-
Speckmann B, Walter PL, Alili L, et al. Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors. Hepatology 2008; 48:1998-2006.
-
(2008)
Hepatology
, vol.48
, pp. 1998-2006
-
-
Speckmann, B.1
Walter, P.L.2
Alili, L.3
-
104
-
-
27644446853
-
Reaction mechanism and regulation of mammalian thioredoxin/glutathione reductase
-
Sun QA, Su D, Novoselov SV, Carlson BA, Hatfield DL, Gladyshev VN. Reaction mechanism and regulation of mammalian thioredoxin/glutathione reductase. Biochemistry 2005; 44: 14528-14537.
-
(2005)
Biochemistry
, vol.44
, pp. 14528-14537
-
-
Sun, Q.A.1
Su, D.2
Novoselov, S.V.3
Carlson, B.A.4
Hatfield, D.L.5
Gladyshev, V.N.6
-
105
-
-
33646067098
-
Involvement of selenoprotein P in protection of human astrocytes from oxidative damage
-
Steinbrenner H, Alili L, Bilgic E, Sies H, Brenneisen P. Involvement of selenoprotein P in protection of human astrocytes from oxidative damage. Free Radic Biol Med 2006; 40: 1513-1523.
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1513-1523
-
-
Steinbrenner, H.1
Alili, L.2
Bilgic, E.3
Sies, H.4
Brenneisen, P.5
-
106
-
-
34547135428
-
Role of FoxO1 in FFA-induced oxidative stress in adipocytes
-
Subauste AR, Burant CF. Role of FoxO1 in FFA-induced oxidative stress in adipocytes. Am J Physiol Endocrinol Metab 2007; 293: E159-E164.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, pp. 159-164
-
-
Subauste, A.R.1
Burant, C.F.2
-
107
-
-
33749331558
-
Differential expression of FOXO1 and FOXO3a confers resistance to oxidative cell death upon endometrial decidualization
-
Kajihara T, Jones M, Fusi L, et al. Differential expression of FOXO1 and FOXO3a confers resistance to oxidative cell death upon endometrial decidualization. Mol Endocrinol 2006; 20:2444-2455.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 2444-2455
-
-
Kajihara, T.1
Jones, M.2
Fusi, L.3
-
108
-
-
19444365211
-
PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells
-
Valle I, Alvarez-Barrientos A, Arza E, Lamas S, Monsalve M. PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc Res 2005; 66: 562-573.
-
(2005)
Cardiovasc Res
, vol.66
, pp. 562-573
-
-
Valle, I.1
Alvarez-Barrientos, A.2
Arza, E.3
Lamas, S.4
Monsalve, M.5
-
109
-
-
33644749330
-
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
-
Kukidome D, Nishikawa T, Sonoda K, et al. Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells. Diabetes 2006; 55: 120-127.
-
(2006)
Diabetes
, vol.55
, pp. 120-127
-
-
Kukidome, D.1
Nishikawa, T.2
Sonoda, K.3
-
110
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, et al. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 2006; 127: 397-408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
-
111
-
-
0038036024
-
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells
-
St-Pierre J, Lin J, Krauss S, et al. Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J Biol Chem 2003; 278: 26597-26603.
-
(2003)
J Biol Chem
, vol.278
, pp. 26597-26603
-
-
St-Pierre, J.1
Lin, J.2
Krauss, S.3
-
112
-
-
67649819237
-
Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes
-
Olmos Y, Valle I, Borniquel S, et al. Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes. J Biol Chem 2009; 284: 14476-14484.
-
(2009)
J Biol Chem
, vol.284
, pp. 14476-14484
-
-
Olmos, Y.1
Valle, I.2
Borniquel, S.3
-
113
-
-
58349118928
-
Interactions between ROS and AMP kinase activity in the regulation of PGC-1alpha transcription in skeletal muscle cells
-
Irrcher I, Ljubicic V, Hood DA. Interactions between ROS and AMP kinase activity in the regulation of PGC-1alpha transcription in skeletal muscle cells. Am J Physiol Cell Physiol 2009; 296: C116-C123.
-
(2009)
Am J Physiol Cell Physiol
, vol.296
, pp. 116-123
-
-
Irrcher, I.1
Ljubicic, V.2
Hood, D.A.3
-
114
-
-
23944476164
-
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha
-
Handschin C, Lin J, Rhee J, et al. Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha. Cell 2005; 122: 505-515.
-
(2005)
Cell
, vol.122
, pp. 505-515
-
-
Handschin, C.1
Lin, J.2
Rhee, J.3
-
115
-
-
0037404976
-
Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs
-
Sugden MC, Holness MJ. Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs. Am J Physiol Endocrinol Metab 2003; 284: E855-E862.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
, pp. 855-862
-
-
Sugden, M.C.1
Holness, M.J.2
-
116
-
-
0034993356
-
Control of pyruvate dehydrogenase kinase gene expression
-
Harris RA, Huang B, Wu P. Control of pyruvate dehydrogenase kinase gene expression. Adv Enzyme Regul 2001; 41: 269-288.
-
(2001)
Adv Enzyme Regul
, vol.41
, pp. 269-288
-
-
Harris, R.A.1
Huang, B.2
Wu, P.3
-
117
-
-
0346158376
-
Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation
-
Holness MJ, Sugden MC. Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation. Biochem Soc Trans 2003; 31: 1143-1151.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1143-1151
-
-
Holness, M.J.1
Sugden, M.C.2
-
118
-
-
1842475551
-
Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors
-
Kwon HS, Huang B, Unterman TG, Harris RA. Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors. Diabetes 2004; 53: 899-910.
-
(2004)
Diabetes
, vol.53
, pp. 899-910
-
-
Kwon, H.S.1
Huang, B.2
Unterman, T.G.3
Harris, R.A.4
-
119
-
-
23844470550
-
Cloning of the rat pyruvate dehydrogenase kinase 4 gene promoter: Activation of pyruvate dehydrogenase kinase 4 by the peroxisome proliferator-activated receptor gamma coactivator
-
Ma K, Zhang Y, Elam MB, Cook GA, Park EA. Cloning of the rat pyruvate dehydrogenase kinase 4 gene promoter: activation of pyruvate dehydrogenase kinase 4 by the peroxisome proliferator-activated receptor gamma coactivator. J Biol Chem 2005; 280: 29525-29532.
-
(2005)
J Biol Chem
, vol.280
, pp. 29525-29532
-
-
Ma, K.1
Zhang, Y.2
Elam, M.B.3
Cook, G.A.4
Park, E.A.5
-
120
-
-
0142200472
-
Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation
-
Furuyama T, Kitayama K, Yamashita H, Mori N. Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation. Biochem J 2003; 375: 365-371.
-
(2003)
Biochem J
, vol.375
, pp. 365-371
-
-
Furuyama, T.1
Kitayama, K.2
Yamashita, H.3
Mori, N.4
-
121
-
-
34247554887
-
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma
-
Dufour CR, Wilson BJ, Huss JM, et al. Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metab 2007; 5: 345-356.
-
(2007)
Cell Metab
, vol.5
, pp. 345-356
-
-
Dufour, C.R.1
Wilson, B.J.2
Huss, J.M.3
-
122
-
-
33845973409
-
Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression
-
Zhang Y, Ma K, Sadana P, et al. Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression. J Biol Chem 2006; 281: 39897-39906.
-
(2006)
J Biol Chem
, vol.281
, pp. 39897-39906
-
-
Zhang, Y.1
Ma, K.2
Sadana, P.3
-
123
-
-
28544438180
-
PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: A mechanism for transcriptional control of muscle glucose metabolism
-
Wende AR, Huss JM, Schaeffer PJ, Giguere V, Kelly DP. PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism. Mol Cell Biol 2005; 25: 10684-10694.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10684-10694
-
-
Wende, A.R.1
Huss, J.M.2
Schaeffer, P.J.3
Giguere, V.4
Kelly, D.P.5
-
124
-
-
71849109938
-
Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin
-
Connaughton S, Chowdhury F, Attia RR, et al. Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin. Mol Cell Endocrinol 2010; 315: 159-167.
-
(2010)
Mol Cell Endocrinol
, vol.315
, pp. 159-167
-
-
Connaughton, S.1
Chowdhury, F.2
Attia, R.R.3
-
125
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
Stitt TN, Drujan D, Clarke BA, et al. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 2004;14: 395-403.
-
(2004)
Mol Cell
, vol.14
, pp. 395-403
-
-
Stitt, T.N.1
Drujan, D.2
Clarke, B.A.3
-
126
-
-
4544358547
-
Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control
-
Kamei Y, Miura S, Suzuki M, et al. Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control. J Biol Chem 2004; 279: 41114-41123.
-
(2004)
J Biol Chem
, vol.279
, pp. 41114-41123
-
-
Kamei, Y.1
Miura, S.2
Suzuki, M.3
-
127
-
-
33750697655
-
Epstein-Barr virus represses the FoxO1 transcription factor through latent membrane protein 1 and latent membrane protein 2A
-
Shore AM, White PC, Hui RC, et al. Epstein-Barr virus represses the FoxO1 transcription factor through latent membrane protein 1 and latent membrane protein 2A. J Virol 2006; 80: 11191-11199.
-
(2006)
J Virol
, vol.80
, pp. 11191-11199
-
-
Shore, A.M.1
White, P.C.2
Hui, R.C.3
-
128
-
-
41849150779
-
FOXOs, cancer and regulation of apoptosis
-
Fu Z, Tindall DJ. FOXOs, cancer and regulation of apoptosis. Oncogene 2008; 27: 2312-2319.
-
(2008)
Oncogene
, vol.27
, pp. 2312-2319
-
-
Fu, Z.1
Tindall, D.J.2
-
130
-
-
70349243136
-
FoxO1 induces apoptosis in skeletal myotubes in a DNA-binding-dependent manner
-
McLoughlin TJ, Smith SM, DeLong AD, Wang H, Unterman TG, Esser KA. FoxO1 induces apoptosis in skeletal myotubes in a DNA-binding-dependent manner. Am J Physiol Cell Physiol 2009; 297: C548-C555.
-
(2009)
Am J Physiol Cell Physiol
, vol.297
, pp. 548-555
-
-
McLoughlin, T.J.1
Smith, S.M.2
Delong, A.D.3
Wang, H.4
Unterman, T.G.5
Esser, K.A.6
-
131
-
-
42449133390
-
Mechanisms of glucocorticoid-induced myopathy
-
Schakman O, Gilson H, Thissen JP. Mechanisms of glucocorticoid-induced myopathy. J Endocrinol 2008; 197: 1-10.
-
(2008)
J Endocrinol
, vol.197
, pp. 1-10
-
-
Schakman, O.1
Gilson, H.2
Thissen, J.P.3
-
132
-
-
56049123409
-
The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene
-
Waddell DS, Baehr LM, van den Brandt J, et al. The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene. Am J Physiol Endocrinol Metab 2008; 295: E785-E797.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, pp. 785-797
-
-
Waddell, D.S.1
Baehr, L.M.2
van den Brandt, J.3
-
133
-
-
23944483998
-
Novel aspects on the regulation of muscle wasting in sepsis
-
Hasselgren PO, Menconi MJ, Fareed MU, Yang H, Wei W, Evenson A. Novel aspects on the regulation of muscle wasting in sepsis. Int J Biochem Cell Biol 2005; 37: 2156-2168.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 2156-2168
-
-
Hasselgren, P.O.1
Menconi, M.J.2
Fareed, M.U.3
Yang, H.4
Wei, W.5
Evenson, A.6
-
134
-
-
0036087321
-
C/EBP DNA-binding activity is upregulated by a glucocorticoid-dependent mechanism in septic muscle
-
Penner G, Gang G, Sun X, Wray C, Hasselgren PO. C/EBP DNA-binding activity is upregulated by a glucocorticoid-dependent mechanism in septic muscle. Am J Physiol Regul Integr Comp Physiol 2002; 282: R439-R444.
-
(2002)
Am J Physiol Regul Integr Comp Physiol
, vol.282
, pp. 439-444
-
-
Penner, G.1
Gang, G.2
Sun, X.3
Wray, C.4
Hasselgren, P.O.5
-
135
-
-
20144365306
-
Expression and activity of C/EBPbeta and delta are upregulated by dexamethasone in skeletal muscle
-
Yang H, Mammen J, Wei W, et al. Expression and activity of C/EBPbeta and delta are upregulated by dexamethasone in skeletal muscle. J Cell Physiol 2005; 204: 219-226.
-
(2005)
J Cell Physiol
, vol.204
, pp. 219-226
-
-
Yang, H.1
Mammen, J.2
Wei, W.3
-
136
-
-
23944524470
-
Dexamethasone upregulates the expression of the nuclear cofactor p300 and its interaction with C/EBPbeta in cultured myotubes
-
Yang H, Menconi MJ, Wei W, Petkova V, Hasselgren PO. Dexamethasone upregulates the expression of the nuclear cofactor p300 and its interaction with C/EBPbeta in cultured myotubes. J Cell Biochem 2005; 94: 1058-1067.
-
(2005)
J Cell Biochem
, vol.94
, pp. 1058-1067
-
-
Yang, H.1
Menconi, M.J.2
Wei, W.3
Petkova, V.4
Hasselgren, P.O.5
-
137
-
-
57049104503
-
Foxo1 increases pro-inflammatory gene expression by inducing C/EBPbeta in TNF-alpha-treated adipocytes
-
Ito Y, Daitoku H, Fukamizu A. Foxo1 increases pro-inflammatory gene expression by inducing C/EBPbeta in TNF-alpha-treated adipocytes. Biochem Biophys Res Commun 2009; 378: 290-295.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 290-295
-
-
Ito, Y.1
Daitoku, H.2
Fukamizu, A.3
-
138
-
-
33750825245
-
PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
-
Sandri M, Lin J, Handschin C, et al. PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc Natl Acad Sci U S A. 2006; 103: 16260-16265.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16260-16265
-
-
Sandri, M.1
Lin, J.2
Handschin, C.3
-
139
-
-
9644270401
-
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex
-
Li HH, Kedar V, Zhang C, et al. Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex. J Clin Invest. 2004; 114: 1058-1071.
-
(2004)
J Clin Invest
, vol.114
, pp. 1058-1071
-
-
Li, H.H.1
Kedar, V.2
Zhang, C.3
-
140
-
-
36049026136
-
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins
-
Li HH, Willis MS, Lockyer P, et al. Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins. J Clin Invest 2007; 117: 3211-3223.
-
(2007)
J Clin Invest
, vol.117
, pp. 3211-3223
-
-
Li, H.H.1
Willis, M.S.2
Lockyer, P.3
-
141
-
-
33748675304
-
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling
-
Ni YG, Berenji K, Wang N, et al. Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling. Circulation 2006; 114: 1159-1168.
-
(2006)
Circulation
, vol.114
, pp. 1159-1168
-
-
Ni, Y.G.1
Berenji, K.2
Wang, N.3
-
142
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander G, Guarente L. The Sir2 family of protein deacetylases. Annu Rev Biochem 2004; 73: 417-435.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
143
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000; 403: 795-800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
144
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001; 410: 227-230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
145
-
-
0033600176
-
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
-
Frye RA. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem Biophys Res Commun 1999; 260: 273-279.
-
(1999)
Biochem Biophys Res Commun
, vol.260
, pp. 273-279
-
-
Frye, R.A.1
-
146
-
-
20144365700
-
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylationpromotes expression of glucogenetic genes
-
Frescas D, Valenti L, Accili D. Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylationpromotes expression of glucogenetic genes. J Biol Chem 2005 280: 20589-20595.
-
(2005)
J Biol Chem
, vol.280
, pp. 20589-20595
-
-
Frescas, D.1
Valenti, L.2
Accili, D.3
-
147
-
-
71449105535
-
FoxO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrol
-
Ganjam GK, Dimova EY, Unterman TG, Kietzmann T. FoxO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrol. J Biol Chem 2009; 284: 30783-30797.
-
(2009)
J Biol Chem
, vol.284
, pp. 30783-30797
-
-
Ganjam, G.K.1
Dimova, E.Y.2
Unterman, T.G.3
Kietzmann, T.4
-
148
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta MC, Divecha N, Lemieux M, et al. Mammalian SIRT1 represses forkhead transcription factors. Cell 2004; 116: 551-563.
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
-
149
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
-
van der Horst A, Tertoolen LG, de Vries-Smits LM, Frye RA, Medema RH, Burgering BM. FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). J Biol Chem 2004; 279: 28873-28879.
-
(2004)
J Biol Chem
, vol.279
, pp. 28873-28879
-
-
van der Horst, A.1
Tertoolen, L.G.2
de Vries-Smits, L.M.3
Frye, R.A.4
Medema, R.H.5
Burgering, B.M.6
-
150
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
Alcendor RR, Gao S, Zhai P, et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 2007; 100: 1512-1521.
-
(2007)
Circ Res
, vol.100
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
-
151
-
-
35348980724
-
SIRT1 controls endothelial angiogenic functions during vascular growth
-
Potente M, Ghaeni L, Baldessari D, et al. SIRT1 controls endothelial angiogenic functions during vascular growth. Genes Dev 2007; 21: 2644-2658.
-
(2007)
Genes Dev
, vol.21
, pp. 2644-2658
-
-
Potente, M.1
Ghaeni, L.2
Baldessari, D.3
-
152
-
-
33846005165
-
A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression
-
Abid MR, Shih SC, Otu HH, et al. A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression. J Biol Chem 2006; 281: 35544-35553.
-
(2006)
J Biol Chem
, vol.281
, pp. 35544-35553
-
-
Abid, M.R.1
Shih, S.C.2
Otu, H.H.3
-
153
-
-
34447626095
-
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
-
Wang F, Nguyen M, Qin FX, Tong Q. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell 2007; 6: 505-514.
-
(2007)
Aging Cell
, vol.6
, pp. 505-514
-
-
Wang, F.1
Nguyen, M.2
Qin, F.X.3
Tong, Q.4
-
154
-
-
10744232772
-
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
-
Rose G, Dato S, Altomare K, et al. Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly. Exp Gerontol 2003; 38: 1065-1070.
-
(2003)
Exp Gerontol
, vol.38
, pp. 1065-1070
-
-
Rose, G.1
Dato, S.2
Altomare, K.3
-
155
-
-
19944433088
-
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages
-
Bellizzi D, Rose G, Cavalcante P, et al. A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. Genomics 2005; 85: 258-263.
-
(2005)
Genomics
, vol.85
, pp. 258-263
-
-
Bellizzi, D.1
Rose, G.2
Cavalcante, P.3
-
156
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
Schwer B, North BJ, Frye RA, Ott M, Verdin E. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol. 2002; 158: 647-657.
-
(2002)
J Cell Biol
, vol.158
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
157
-
-
34247271282
-
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
-
Scher MB, Vaquero A, Reinberg D. SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. Genes Dev 2007; 21: 920-928.
-
(2007)
Genes Dev
, vol.21
, pp. 920-928
-
-
Scher, M.B.1
Vaquero, A.2
Reinberg, D.3
-
158
-
-
51449083112
-
SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression
-
Jacobs KM, Pennington JD, Bisht KS, et al. SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression. Int J Biol Sci 2008; 4:2 91-99.
-
(2008)
Int J Biol Sci
, vol.4
, Issue.2
, pp. 91-99
-
-
Jacobs, K.M.1
Pennington, J.D.2
Bisht, K.S.3
-
159
-
-
70349208608
-
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
-
Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A, Gupta MP. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest 2009; 119: 2758-2771.
-
(2009)
J Clin Invest
, vol.119
, pp. 2758-2771
-
-
Sundaresan, N.R.1
Gupta, M.2
Kim, G.3
Rajamohan, S.B.4
Isbatan, A.5
Gupta, M.P.6
-
160
-
-
0037376913
-
Glucagon and regulation of glucose metabolism
-
Jiang G, Zhang BB. Glucagon and regulation of glucose metabolism. Am J Physiol Endocrinol Metab 2003; 284: E671-E678.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
, pp. 671-678
-
-
Jiang, G.1
Zhang, B.B.2
-
161
-
-
27144506185
-
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
-
Koo SH, Flechner L, Qi L, et al. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 2005; 437: 1109-1111.
-
(2005)
Nature
, vol.437
, pp. 1109-1111
-
-
Koo, S.H.1
Flechner, L.2
Qi, L.3
-
162
-
-
0035855905
-
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
-
Herzig S, Long F, Jhala US, et al. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 2001; 413: 179-183.
-
(2001)
Nature
, vol.413
, pp. 179-183
-
-
Herzig, S.1
Long, F.2
Jhala, U.S.3
-
163
-
-
56249100986
-
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
-
Liu Y, Dentin R, Chen D, et al. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 2008; 456: 269-273.
-
(2008)
Nature
, vol.456
, pp. 269-273
-
-
Liu, Y.1
Dentin, R.2
Chen, D.3
-
164
-
-
5444264003
-
Biological control through regulated transcriptional coactivators
-
Spiegelman BM, Heinrich R. Biological control through regulated transcriptional coactivators. Cell 2004; 119: 157-167.
-
(2004)
Cell
, vol.119
, pp. 157-167
-
-
Spiegelman, B.M.1
Heinrich, R.2
-
165
-
-
12944335299
-
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
-
Nasrin N, Ogg S, Cahill CM, et al. DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells. Proc Natl Acad Sci USA 2000; 97: 10412-10417.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10412-10417
-
-
Nasrin, N.1
Ogg, S.2
Cahill, C.M.3
-
166
-
-
24344499875
-
The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription
-
Perrot V, Rechler MM. The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription. Mol Endocrinol 2005; 19: 2283-2298.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 2283-2298
-
-
Perrot, V.1
Rechler, M.M.2
-
167
-
-
85047695408
-
Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells
-
Mahmud DL, M GA, Deb DK, Platanias LC, Uddin S, Wickrema A. Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells. Oncogene 2002; 21: 1556-1562.
-
(2002)
Oncogene
, vol.21
, pp. 1556-1562
-
-
Mahmud, D.L.1
Ga, M.2
Deb, D.K.3
Platanias, L.C.4
Uddin, S.5
Wickrema, A.6
-
168
-
-
2342445654
-
Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation
-
Fukuoka M, Daitoku H, Hatta M, Matsuzaki H, Umemura S, Fukamizu A. Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation. Int J Mol Med 2003; 12: 503-508.
-
(2003)
Int J Mol Med
, vol.12
, pp. 503-508
-
-
Fukuoka, M.1
Daitoku, H.2
Hatta, M.3
Matsuzaki, H.4
Umemura, S.5
Fukamizu, A.6
-
169
-
-
24744469490
-
SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress
-
Kobayashi Y, Furukawa-Hibi Y, Chen C, et al. SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress. Int J Mol Med 2005; 16: 237-243.
-
(2005)
Int J Mol Med
, vol.16
, pp. 237-243
-
-
Kobayashi, Y.1
Furukawa-Hibi, Y.2
Chen, C.3
-
170
-
-
3042750643
-
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
-
Daitoku H, Hatta M, Matsuzaki H, et al. Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. Proc Natl Acad Sci USA 2004; 101: 10042-10047.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
-
171
-
-
34547397081
-
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
-
Jing E, Gesta S, Kahn CR. SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation. Cell Metab 2007; 6: 105-114.
-
(2007)
Cell Metab
, vol.6
, pp. 105-114
-
-
Jing, E.1
Gesta, S.2
Kahn, C.R.3
-
172
-
-
23844485211
-
Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation
-
Matsuzaki H, Daitoku H, Hatta M, Aoyama H, Yoshimochi K, Fukamizu A. Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation. Proc Natl Acad Sci USA 2005; 102: 11278-11283.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11278-11283
-
-
Matsuzaki, H.1
Daitoku, H.2
Hatta, M.3
Aoyama, H.4
Yoshimochi, K.5
Fukamizu, A.6
-
173
-
-
58949091250
-
Acetylation curtails nucleosome binding, not stable nucleosome remodeling, by FoxO1
-
Hatta M, Liu F, Cirillo LA. Acetylation curtails nucleosome binding, not stable nucleosome remodeling, by FoxO1. Biochem Biophys Res Commun 2009; 379:1005-1008.
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 1005-1008
-
-
Hatta, M.1
Liu, F.2
Cirillo, L.A.3
-
174
-
-
16344384026
-
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
-
Yang Y, Hou H, Haller EM, Nicosia SV, Bai W. Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. EMBO J 2005; 24: 1021-1032.
-
(2005)
EMBO J
, vol.24
, pp. 1021-1032
-
-
Yang, Y.1
Hou, H.2
Haller, E.M.3
Nicosia, S.V.4
Bai, W.5
-
175
-
-
69249229450
-
Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity
-
Dansen TB, Smits LM, van Triest MH, et al. Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity. Nat Chem Biol 2009; 5: 664-72.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 664-672
-
-
Dansen, T.B.1
Smits, L.M.2
van Triest, M.H.3
-
176
-
-
0019026208
-
Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
-
Embi N, Rylatt DB, Cohen P. Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 1980; 107: 519-527.
-
(1980)
Eur J Biochem
, vol.107
, pp. 519-527
-
-
Embi, N.1
Rylatt, D.B.2
Cohen, P.3
-
177
-
-
0026353474
-
CDNA cloning and properties of glycogen synthase kinase-3
-
Woodgett JR. CDNA cloning and properties of glycogen synthase kinase-3. Methods Enzymol 1991; 200: 564-577.
-
(1991)
Methods Enzymol
, vol.200
, pp. 564-577
-
-
Woodgett, J.R.1
-
178
-
-
0025286104
-
Molecular cloning and expression of glycogen synthase kinase-3/factor A
-
Woodgett JR. Molecular cloning and expression of glycogen synthase kinase-3/factor A. Embo J 1990; 9: 2431-2438.
-
(1990)
Embo J
, vol.9
, pp. 2431-2438
-
-
Woodgett, J.R.1
-
179
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378: 785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
180
-
-
0034461612
-
Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta
-
Li M, Wang X, Meintzer MK, Laessig T, Birnbaum MJ, Heidenreich KA. Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta. Mol Cell Biol 2000; 20: 9356-9363.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9356-9363
-
-
Li, M.1
Wang, X.2
Meintzer, M.K.3
Laessig, T.4
Birnbaum, M.J.5
Heidenreich, K.A.6
-
181
-
-
12944250922
-
Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A
-
Fang X, Yu SX, Lu Y, Bast RC, Jr., Woodgett JR, Mills GB. Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. Proc Natl Acad Sci USA 2000; 97: 11960-11965.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11960-11965
-
-
Fang, X.1
Yu, S.X.2
Lu, Y.3
Bast Jr., R.C.4
Woodgett, J.R.5
Mills, G.B.6
-
182
-
-
0027430039
-
Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B
-
Welsh GI, Proud CG. Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B. Biochem J 1993; 294: 625-629.
-
(1993)
Biochem J
, vol.294
, pp. 625-629
-
-
Welsh, G.I.1
Proud, C.G.2
-
183
-
-
0032498112
-
Regulation of eukaryotic initiation factor eIF2B: Glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin
-
Welsh GI, Miller CM, Loughlin AJ, Price NT, Proud CG. Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin. FEBS Lett 1998; 421: 125-130.
-
(1998)
FEBS Lett
, vol.421
, pp. 125-130
-
-
Welsh, G.I.1
Miller, C.M.2
Loughlin, A.J.3
Price, N.T.4
Proud, C.G.5
-
185
-
-
0033851276
-
GSK3, a master switch regulating cell-fate specification and tumorigenesis
-
Kim L, Kimmel AR. GSK3, a master switch regulating cell-fate specification and tumorigenesis. Curr Opin Genet Dev 2000; 10: 508-514.
-
(2000)
Curr Opin Genet Dev
, vol.10
, pp. 508-514
-
-
Kim, L.1
Kimmel, A.R.2
-
187
-
-
33845355511
-
Diversity of LEF/TCF action in development and disease
-
Arce L, Yokoyama NN, Waterman ML. Diversity of LEF/TCF action in development and disease. Oncogene 2006; 25: 7492-7504.
-
(2006)
Oncogene
, vol.25
, pp. 7492-7504
-
-
Arce, L.1
Yokoyama, N.N.2
Waterman, M.L.3
-
188
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame S, Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem J 2001; 359: 1-16.
-
(2001)
Biochem J
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
189
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009; 324: 1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander, H.M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
190
-
-
44049092138
-
Interaction of FOXO with beta-catenin inhibits beta-catenin/T cell factor activity
-
Hoogeboom D, Essers MA, Polderman PE, Voets E, Smits LM, Burgering BM. Interaction of FOXO with beta-catenin inhibits beta-catenin/T cell factor activity. J Biol Chem 2008; 283: 9224-9230.
-
(2008)
J Biol Chem
, vol.283
, pp. 9224-9230
-
-
Hoogeboom, D.1
Essers, M.A.2
Polderman, P.E.3
Voets, E.4
Smits, L.M.5
Burgering, B.M.6
-
191
-
-
40349098058
-
Glycogen synthase kinase 3 (GSK3) in the heart: A point of integration in hypertrophic signalling and a therapeutic target? A critical analysis
-
Sugden PH, Fuller SJ, Weiss SC, Clerk A. Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis. Br J Pharmacol 2008; 153: S137-S153.
-
(2008)
Br J Pharmacol
, vol.153
, pp. 137-153
-
-
Sugden, P.H.1
Fuller, S.J.2
Weiss, S.C.3
Clerk, A.4
-
192
-
-
37849041966
-
Forkhead transcription factors and cardiovascular biology
-
Papanicolaou KN, Izumiya Y, Walsh K. Forkhead transcription factors and cardiovascular biology. Circ Res 2008; 102: 16-31.
-
(2008)
Circ Res
, vol.102
, pp. 16-31
-
-
Papanicolaou, K.N.1
Izumiya, Y.2
Walsh, K.3
-
193
-
-
33846295218
-
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
-
Paik JH, Kollipara R, Chu G, et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 2007; 128: 309-323.
-
(2007)
Cell
, vol.128
, pp. 309-323
-
-
Paik, J.H.1
Kollipara, R.2
Chu, G.3
-
194
-
-
34447504987
-
Perspectives on endothelial-to-mesenchymal transition: Potential contribution to vascular remodeling in chronic pulmonary hypertension
-
Arciniegas E, Frid MG, Douglas IS, Stenmark KR. Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2007; 293: L1-8.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
, pp. 1-8
-
-
Arciniegas, E.1
Frid, M.G.2
Douglas, I.S.3
Stenmark, K.R.4
-
195
-
-
3042588831
-
Molecular regulation of vascular smooth muscle cell differentiation in development and disease
-
Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 2004 J; 84: 767-801.
-
Physiol Rev 2004 J
, vol.84
, pp. 767-801
-
-
Owens, G.K.1
Kumar, M.S.2
Wamhoff, B.R.3
-
196
-
-
34249736457
-
Programming smooth muscle plasticity with chromatin dynamics
-
McDonald OG, Owens GK. Programming smooth muscle plasticity with chromatin dynamics. Circ Res 2007; 100: 1428-1441.
-
(2007)
Circ Res
, vol.100
, pp. 1428-1441
-
-
McDonald, O.G.1
Owens, G.K.2
-
197
-
-
33745152386
-
The myocardin family of transcriptional coactivators: Versatile regulators of cell growth, migration, and myogenesis
-
Pipes GC, Creemers EE, Olson EN. The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. Genes Dev 2006; 20: 1545-1556.
-
(2006)
Genes Dev
, vol.20
, pp. 1545-1556
-
-
Pipes, G.C.1
Creemers, E.E.2
Olson, E.N.3
-
198
-
-
0027425113
-
Activation of ternary complex factor Elk-1 by MAP kinases
-
Janknecht R, Ernst WH, Pingoud V, Nordheim A. Activation of ternary complex factor Elk-1 by MAP kinases. Embo J 1993; 12: 5097-5104.
-
(1993)
Embo J
, vol.12
, pp. 5097-5104
-
-
Janknecht, R.1
Ernst, W.H.2
Pingoud, V.3
Nordheim, A.4
-
199
-
-
1642297200
-
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression
-
Wang Z, Wang DZ, Hockemeyer D, McAnally J, Nordheim A, Olson EN. Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature 2004; 428: 185-189.
-
(2004)
Nature
, vol.428
, pp. 185-189
-
-
Wang, Z.1
Wang, D.Z.2
Hockemeyer, D.3
McAnally, J.4
Nordheim, A.5
Olson, E.N.6
-
200
-
-
0038737042
-
Actin dynamics control SRF activity by regulation of its coactivator MAL
-
Miralles F, Posern G, Zaromytidou AI, Treisman R. Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell 2003; 113: 329-342.
-
(2003)
Cell
, vol.113
, pp. 329-342
-
-
Miralles, F.1
Posern, G.2
Zaromytidou, A.I.3
Treisman, R.4
-
201
-
-
0032582808
-
Differentiated phenotype of smooth muscle cells depends on signaling pathways through insulin-like growth factors and phosphatidylinositol 3-kinase
-
Hayashi K, Saga H, Chimori Y, Kimura K, Yamanaka Y, Sobue K. Differentiated phenotype of smooth muscle cells depends on signaling pathways through insulin-like growth factors and phosphatidylinositol 3-kinase. J Biol Chem 1998; 273: 28860-28867.
-
(1998)
J Biol Chem
, vol.273
, pp. 28860-28867
-
-
Hayashi, K.1
Saga, H.2
Chimori, Y.3
Kimura, K.4
Yamanaka, Y.5
Sobue, K.6
-
202
-
-
22944451474
-
Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin
-
Liu ZP, Wang Z, Yanagisawa H, Olson EN. Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. Dev Cell 2005; 9: 261-270.
-
(2005)
Dev Cell
, vol.9
, pp. 261-270
-
-
Liu, Z.P.1
Wang, Z.2
Yanagisawa, H.3
Olson, E.N.4
-
203
-
-
23844491841
-
Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia
-
Abid MR, Yano K, Guo S, et al. Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia. J Biol Chem 2005; 280: 29864-29873.
-
(2005)
J Biol Chem
, vol.280
, pp. 29864-29873
-
-
Abid, M.R.1
Yano, K.2
Guo, S.3
-
204
-
-
0042413919
-
Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells
-
Sedding DG, Seay U, Fink L, et al. Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells. Circulation 2003; 108: 616-622.
-
(2003)
Circulation
, vol.108
, pp. 616-622
-
-
Sedding, D.G.1
Seay, U.2
Fink, L.3
-
205
-
-
0141483026
-
Myocardin mRNA is augmented in the failing myocardium: Expression profiling in the porcine model and human dilated cardiomyopathy
-
Torrado M, Lopez E, Centeno A, Medrano C, Castro-Beiras A, Mikhailov AT. Myocardin mRNA is augmented in the failing myocardium: expression profiling in the porcine model and human dilated cardiomyopathy. J Mol Med 2003; 81: 566-577.
-
(2003)
J Mol Med
, vol.81
, pp. 566-577
-
-
Torrado, M.1
Lopez, E.2
Centeno, A.3
Medrano, C.4
Castro-Beiras, A.5
Mikhailov, A.T.6
-
206
-
-
33646798121
-
Myocardin induces cardiomyocyte hypertrophy
-
Xing W, Zhang TC, Cao D, et al. Myocardin induces cardiomyocyte hypertrophy. Circ Res 2006; 98: 1089-1097.
-
(2006)
Circ Res
, vol.98
, pp. 1089-1097
-
-
Xing, W.1
Zhang, T.C.2
Cao, D.3
-
207
-
-
26244440041
-
Glycogen synthase kinase 3beta inhibits myocardin-dependent transcription and hypertrophy induction through site-specific phosphorylation
-
Badorff C, Seeger FH, Zeiher AM, Dimmeler S. Glycogen synthase kinase 3beta inhibits myocardin-dependent transcription and hypertrophy induction through site-specific phosphorylation. Circ Res 2005; 97: 645-654.
-
(2005)
Circ Res
, vol.97
, pp. 645-654
-
-
Badorff, C.1
Seeger, F.H.2
Zeiher, A.M.3
Dimmeler, S.4
-
208
-
-
33751534932
-
Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development
-
Creemers EE, Sutherland LB, McAnally J, Richardson JA, Olson EN. Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development. Development 2006; 133: 4245-4256.
-
(2006)
Development
, vol.133
, pp. 4245-4256
-
-
Creemers, E.E.1
Sutherland, L.B.2
McAnally, J.3
Richardson, J.A.4
Olson, E.N.5
-
209
-
-
34147195312
-
FoxO4 regulates tumor necrosis factor alpha-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcription
-
Li H, Liang J, Castrillon DH, DePinho RA, Olson EN, Liu ZP. FoxO4 regulates tumor necrosis factor alpha-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcription. Mol Cell Biol 2007; 27: 2676-2686.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2676-2686
-
-
Li, H.1
Liang, J.2
Castrillon, D.H.3
Depinho, R.A.4
Olson, E.N.5
Liu, Z.P.6
-
210
-
-
63649158684
-
FoxO1 inhibits leptin regulation of pro-opiomelanocortin promoter activity by blocking STAT3 interaction with specificity protein 1
-
Yang G, Lim CY, Li C, et al. FoxO1 inhibits leptin regulation of pro-opiomelanocortin promoter activity by blocking STAT3 interaction with specificity protein 1. J Biol Chem 2009; 284: 3719-3727.
-
(2009)
J Biol Chem
, vol.284
, pp. 3719-3727
-
-
Yang, G.1
Lim, C.Y.2
Li, C.3
-
211
-
-
36849053911
-
Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling
-
Morita T, Mayanagi T, Sobue K. Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling. J Cell Biol 2007; 179: 1027-1042.
-
(2007)
J Cell Biol
, vol.179
, pp. 1027-1042
-
-
Morita, T.1
Mayanagi, T.2
Sobue, K.3
-
212
-
-
69249208738
-
Regulation of myocardin-related transcriptional coactivators through cofactor interactions in differentiation and cancer
-
Brandt DT, Xu J, Steinbeisser H, Grosse R. Regulation of myocardin-related transcriptional coactivators through cofactor interactions in differentiation and cancer. Cell Cycle 2009; 8: 2523-2527.
-
(2009)
Cell Cycle
, vol.8
, pp. 2523-2527
-
-
Brandt, D.T.1
Xu, J.2
Steinbeisser, H.3
Grosse, R.4
-
213
-
-
51049114512
-
Rho/Rho-associated kinase signal regulates myogenic differentiation via myocardin-related transcription factor-A/Smad-dependent transcription of the Id3 gene
-
Iwasaki K, Hayashi K, Fujioka T, Sobue K. Rho/Rho-associated kinase signal regulates myogenic differentiation via myocardin-related transcription factor-A/Smad-dependent transcription of the Id3 gene. J Biol Chem 2008; 283: 21230-21241.
-
(2008)
J Biol Chem
, vol.283
, pp. 21230-21241
-
-
Iwasaki, K.1
Hayashi, K.2
Fujioka, T.3
Sobue, K.4
-
214
-
-
27944454815
-
Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes
-
Callis TE, Cao D, Wang DZ. Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes. Circ Res 2005; 97: 992-1000.
-
(2005)
Circ Res
, vol.97
, pp. 992-1000
-
-
Callis, T.E.1
Cao, D.2
Wang, D.Z.3
-
215
-
-
27944445459
-
Myocardin enhances Smad3-mediated transforming growth factor-beta1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22alpha transcription in vivo
-
Qiu P, Ritchie RP, Fu Z, et al. Myocardin enhances Smad3-mediated transforming growth factor-beta1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22alpha transcription in vivo. Circ Res 2005; 97: 983-991.
-
(2005)
Circ Res
, vol.97
, pp. 983-991
-
-
Qiu, P.1
Ritchie, R.P.2
Fu, Z.3
-
216
-
-
33644857012
-
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism
-
Ayyanan A, Civenni G, Ciarloni L, et al. Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism. Proc Natl Acad Sci USA 2006; 103: 3799-3804.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3799-3804
-
-
Ayyanan, A.1
Civenni, G.2
Ciarloni, L.3
-
217
-
-
27144504699
-
The Notch pathway in ovarian carcinomas and adenomas
-
Hopfer O, Zwahlen D, Fey MF, Aebi S. The Notch pathway in ovarian carcinomas and adenomas. Br J Cancer 2005; 93:709-718.
-
(2005)
Br J Cancer
, vol.93
, pp. 709-718
-
-
Hopfer, O.1
Zwahlen, D.2
Fey, M.F.3
Aebi, S.4
-
218
-
-
7244250027
-
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
-
Pece S, Serresi M, Santolini E, et al. Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J Cell Biol 2004; 167: 215-221.
-
(2004)
J Cell Biol
, vol.167
, pp. 215-221
-
-
Pece, S.1
Serresi, M.2
Santolini, E.3
-
219
-
-
0036734148
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
-
Weijzen S, Rizzo P, Braid M, et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med 2002; 8: 979-986.
-
(2002)
Nat Med
, vol.8
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
-
220
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
-
Ellisen LW, Bird J, West DC, et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991; 66: 649-661.
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
-
221
-
-
0942287279
-
Embryonic myogenesis pathways in muscle regeneration
-
Zhao P, Hoffman EP. Embryonic myogenesis pathways in muscle regeneration. Dev Dyn 2004; 229: 380-392.
-
(2004)
Dev Dyn
, vol.229
, pp. 380-392
-
-
Zhao, P.1
Hoffman, E.P.2
-
222
-
-
24344443668
-
The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis
-
Luo D, Renault VM, Rando TA. The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis. Semin Cell Dev Biol 2005; 16: 612-622.
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 612-622
-
-
Luo, D.1
Renault, V.M.2
Rando, T.A.3
-
223
-
-
0032915458
-
Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
-
Nofziger D, Miyamoto A, Lyons KM, Weinmaster G. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts. Development 1999; 126: 1689-1702.
-
(1999)
Development
, vol.126
, pp. 1689-1702
-
-
Nofziger, D.1
Miyamoto, A.2
Lyons, K.M.3
Weinmaster, G.4
-
224
-
-
0033548489
-
Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis
-
Kuroda K, Tani S, Tamura K, Minoguchi S, Kurooka H, Honjo T. Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis. J Biol Chem 1999; 274: 7238-7244.
-
(1999)
J Biol Chem
, vol.274
, pp. 7238-7244
-
-
Kuroda, K.1
Tani, S.2
Tamura, K.3
Minoguchi, S.4
Kurooka, H.5
Honjo, T.6
-
225
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
Sandri M, Sandri C, Gilbert A, et al. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 2004; 117: 399-412.
-
(2004)
Cell
, vol.117
, pp. 399-412
-
-
Sandri, M.1
Sandri, C.2
Gilbert, A.3
-
226
-
-
0042769210
-
Forkhead transcription factor FoxO1 transduces insulin-like growth factor's signal to p27Kip1 in primary skeletal muscle satellite cells
-
Machida S, Spangenburg EE, Booth FW. Forkhead transcription factor FoxO1 transduces insulin-like growth factor's signal to p27Kip1 in primary skeletal muscle satellite cells. J Cell Physiol 2003; 196: 523-531.
-
(2003)
J Cell Physiol
, vol.196
, pp. 523-531
-
-
Machida, S.1
Spangenburg, E.E.2
Booth, F.W.3
-
227
-
-
0037416153
-
FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts
-
Bois PR, Grosveld GC. FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts. Embo J 2003; 22: 1147-1157.
-
(2003)
Embo J
, vol.22
, pp. 1147-1157
-
-
Bois, P.R.1
Grosveld, G.C.2
-
228
-
-
34848838902
-
A Foxo/Notch pathway controls myogenic differentiation and fiber type specification
-
Kitamura T, Kitamura YI, Funahashi Y, et al. A Foxo/Notch pathway controls myogenic differentiation and fiber type specification. J Clin Invest 2007; 117: 2477-2485.
-
(2007)
J Clin Invest
, vol.117
, pp. 2477-2485
-
-
Kitamura, T.1
Kitamura, Y.I.2
Funahashi, Y.3
-
229
-
-
34447125200
-
P53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notch1 activity
-
Okuyama R, Ogawa E, Nagoshi H, et al. P53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notch1 activity. Oncogene 2007; 26: 4478-4488.
-
(2007)
Oncogene
, vol.26
, pp. 4478-4488
-
-
Okuyama, R.1
Ogawa, E.2
Nagoshi, H.3
-
230
-
-
22344436360
-
P21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
-
Devgan V, Mammucari C, Millar SE, Brisken C, Dotto GP. P21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev 2005; 19: 1485-1495.
-
(2005)
Genes Dev
, vol.19
, pp. 1485-1495
-
-
Devgan, V.1
Mammucari, C.2
Millar, S.E.3
Brisken, C.4
Dotto, G.P.5
-
231
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
Nicolas M, Wolfer A, Raj K, et al. Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 2003; 33: 416-421.
-
(2003)
Nat Genet
, vol.33
, pp. 416-421
-
-
Nicolas, M.1
Wolfer, A.2
Raj, K.3
-
232
-
-
17844384528
-
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
-
Rangarajan A, Talora C, Okuyama R, et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. Embo J 2001; 20: 3427-3436.
-
(2001)
Embo J
, vol.20
, pp. 3427-3436
-
-
Rangarajan, A.1
Talora, C.2
Okuyama, R.3
-
233
-
-
33947166199
-
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases
-
Lefort K, Mandinova A, Ostano P, et al. Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases. Genes Dev 2007; 21: 562-577.
-
(2007)
Genes Dev
, vol.21
, pp. 562-577
-
-
Lefort, K.1
Mandinova, A.2
Ostano, P.3
-
234
-
-
42449147521
-
The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response
-
Mandinova A, Lefort K, Tommasi di Vignano A, et al. The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response. Embo J 2008; 27: 1243-1254.
-
(2008)
Embo J
, vol.27
, pp. 1243-1254
-
-
Mandinova, A.1
Lefort, K.2
Di Vignano, T.A.3
-
235
-
-
33845331336
-
PAX genes: Roles in development, pathophysiology, and cancer
-
Lang D, Powell SK, Plummer RS, Young KP, Ruggeri BA. PAX genes: roles in development, pathophysiology, and cancer. Biochem Pharmacol 2007; 73:1-14.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 1-14
-
-
Lang, D.1
Powell, S.K.2
Plummer, R.S.3
Young, K.P.4
Ruggeri, B.A.5
-
236
-
-
22344444869
-
Pax3/Pax7 mark a novel population of primitive myogenic cells during development
-
Kassar-Duchossoy L, Giacone E, Gayraud-Morel B, Jory A, Gomes D, Tajbakhsh S. Pax3/Pax7 mark a novel population of primitive myogenic cells during development. Genes Dev 2005; 19: 1426-1431.
-
(2005)
Genes Dev
, vol.19
, pp. 1426-1431
-
-
Kassar-Duchossoy, L.1
Giacone, E.2
Gayraud-Morel, B.3
Jory, A.4
Gomes, D.5
Tajbakhsh, S.6
-
237
-
-
33845808721
-
Myogenic progenitor cells in the mouse embryo are marked by the expression of Pax3/7 genes that regulate their survival and myogenic potential
-
Buckingham M, Bajard L, Daubas P, et al. Myogenic progenitor cells in the mouse embryo are marked by the expression of Pax3/7 genes that regulate their survival and myogenic potential. Anat Embryol (Berl) 2006; 211: 51-56.
-
(2006)
Anat Embryol (Berl)
, vol.211
, pp. 51-56
-
-
Buckingham, M.1
Bajard, L.2
Daubas, P.3
-
238
-
-
0030891318
-
Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue
-
Maroto M, Reshef R, Munsterberg AE, Koester S, Goulding M, Lassar AB. Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue. Cell 1997; 89: 139-148.
-
(1997)
Cell
, vol.89
, pp. 139-148
-
-
Maroto, M.1
Reshef, R.2
Munsterberg, A.E.3
Koester, S.4
Goulding, M.5
Lassar, A.B.6
-
239
-
-
0028205002
-
Pax-3 is required for the development of limb muscles: A possible role for the migration of dermomyotomal muscle progenitor cells
-
Bober E, Franz T, Arnold HH, Gruss P, Tremblay P. Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells. Development 1994; 120: 603-612.
-
(1994)
Development
, vol.120
, pp. 603-612
-
-
Bober, E.1
Franz, T.2
Arnold, H.H.3
Gruss, P.4
Tremblay, P.5
-
240
-
-
33847309514
-
Fusions involving PAX and FOX genes in the molecular pathogenesis of alveolar rhabdomyosarcoma: Recent advances
-
Mercado GE, Barr FG. Fusions involving PAX and FOX genes in the molecular pathogenesis of alveolar rhabdomyosarcoma: recent advances. Curr Mol Med 2007; 7: 47-61.
-
(2007)
Curr Mol Med
, vol.7
, pp. 47-61
-
-
Mercado, G.E.1
Barr, F.G.2
-
241
-
-
53249095869
-
Codependent activators direct myoblast-specific MyoD transcription
-
Hu P, Geles KG, Paik JH, DePinho RA, Tjian R. Codependent activators direct myoblast-specific MyoD transcription. Dev Cell 2008; 15: 534-546.
-
(2008)
Dev Cell
, vol.15
, pp. 534-546
-
-
Hu, P.1
Geles, K.G.2
Paik, J.H.3
Depinho, R.A.4
Tjian, R.5
-
242
-
-
0242499448
-
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
-
Siegel PM, Massague J. Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer 2003; 3: 807-821.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 807-821
-
-
Siegel, P.M.1
Massague, J.2
-
243
-
-
23044466047
-
Specificity and versatility in tgf-beta signaling through Smads
-
Feng XH, Derynck R. Specificity and versatility in tgf-beta signaling through Smads. Annu Rev Cell Dev Biol 2005; 21: 659-693.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
244
-
-
31944433741
-
TGF-beta/Smad signaling in the injured liver
-
Breitkopf K, Godoy P, Ciuclan L, Singer MV, Dooley S. TGF-beta/Smad signaling in the injured liver. Z Gastroenterol 2006; 44: 57-66.
-
(2006)
Z Gastroenterol
, vol.44
, pp. 57-66
-
-
Breitkopf, K.1
Godoy, P.2
Ciuclan, L.3
Singer, M.V.4
Dooley, S.5
-
245
-
-
47849127561
-
Fibrosis in diabetes complications: Pathogenic mechanisms and circulating and urinary markers
-
Ban CR, Twigg SM. Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers. Vasc Health Risk Manag 2008; 4: 575-596.
-
(2008)
Vasc Health Risk Manag
, vol.4
, pp. 575-596
-
-
Ban, C.R.1
Twigg, S.M.2
-
246
-
-
34748828509
-
Obesity and obesity-initiated metabolic syndrome: Mechanistic links to chronic kidney disease
-
Wahba IM, Mak RH. Obesity and obesity-initiated metabolic syndrome: mechanistic links to chronic kidney disease. Clin J Am Soc Nephrol 2007; 2: 550-562.
-
(2007)
Clin J Am Soc Nephrol
, vol.2
, pp. 550-562
-
-
Wahba, I.M.1
Mak, R.H.2
-
247
-
-
57349083077
-
Transcriptional regulation of the plasminogen activator inhibitor type 1--with an emphasis on negative regulation
-
Nagamine Y. Transcriptional regulation of the plasminogen activator inhibitor type 1--with an emphasis on negative regulation. Thromb Haemost 2008; 100: 1007-1013.
-
(2008)
Thromb Haemost
, vol.100
, pp. 1007-1013
-
-
Nagamine, Y.1
-
248
-
-
20244376914
-
Transforming growth factor-beta and platelet-derived growth factor signal via c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury
-
Yoshida K, Matsuzaki K, Mori S, Tahashi Y, Yamagata H, Furukawa F, et al. Transforming growth factor-beta and platelet-derived growth factor signal via c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury. Am J Pathol 2005; 166: 1029-1039.
-
(2005)
Am J Pathol
, vol.166
, pp. 1029-1039
-
-
Yoshida, K.1
Matsuzaki, K.2
Mori, S.3
Tahashi, Y.4
Yamagata, H.5
Furukawa, F.6
-
249
-
-
0028838983
-
Induction of plasminogen activator inhibitor type-1 (PAI-1) by proinsulin and insulin in vivo
-
Nordt TK, Sawa H, Fujii S, Sobel BE. Induction of plasminogen activator inhibitor type-1 (PAI-1) by proinsulin and insulin in vivo. Circulation 1995; 91: 764-770.
-
(1995)
Circulation
, vol.91
, pp. 764-770
-
-
Nordt, T.K.1
Sawa, H.2
Fujii, S.3
Sobel, B.E.4
-
250
-
-
67650433374
-
Forkhead transcription factor FoxO1 inhibits insulin-and transforming growth factor-beta-stimulated plasminogen activator inhibitor-1 expression
-
Jung YA, Lee KM, Kim MK, Jung GS, Seo YJ, Kim HS, et al. Forkhead transcription factor FoxO1 inhibits insulin-and transforming growth factor-beta-stimulated plasminogen activator inhibitor-1 expression. Biochem Biophys Res Commun 2009; 386: 757-761.
-
(2009)
Biochem Biophys Res Commun
, vol.386
, pp. 757-761
-
-
Jung, Y.A.1
Lee, K.M.2
Kim, M.K.3
Jung, G.S.4
Seo, Y.J.5
Kim, H.S.6
-
251
-
-
0030776478
-
The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway
-
Patterson GI, Koweek A, Wong A, Liu Y, Ruvkun G. The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway. Genes Dev 1997; 11: 2679-2690.
-
(1997)
Genes Dev
, vol.11
, pp. 2679-2690
-
-
Patterson, G.I.1
Koweek, A.2
Wong, A.3
Liu, Y.4
Ruvkun, G.5
-
252
-
-
10544256181
-
Control of C. elegans larval development by neuronal expression of a TGF-beta homolog
-
Ren P, Lim CS, Johnsen R, Albert PS, Pilgrim D, Riddle DL. Control of C. elegans larval development by neuronal expression of a TGF-beta homolog. Science 1996; 274: 1389-1391.
-
(1996)
Science
, vol.274
, pp. 1389-1391
-
-
Ren, P.1
Lim, C.S.2
Johnsen, R.3
Albert, P.S.4
Pilgrim, D.5
Riddle, D.L.6
-
253
-
-
0038369998
-
A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells
-
Kang Y, Chen CR, Massague J. A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. Mol Cell 2003; 11: 915-926.
-
(2003)
Mol Cell
, vol.11
, pp. 915-926
-
-
Kang, Y.1
Chen, C.R.2
Massague, J.3
-
254
-
-
0028953810
-
Transforming growth factor beta and cell cycle regulation
-
Alexandrow MG, Moses HL. Transforming growth factor beta and cell cycle regulation. Cancer Res. 1995; 55: 1452-1457.
-
(1995)
Cancer Res
, vol.55
, pp. 1452-1457
-
-
Alexandrow, M.G.1
Moses, H.L.2
-
255
-
-
33646562542
-
The logic of TGFbeta signaling
-
Massague J, Gomis RR. The logic of TGFbeta signaling. FEBS Lett 2006; 580: 2811-2820.
-
(2006)
FEBS Lett
, vol.580
, pp. 2811-2820
-
-
Massague, J.1
Gomis, R.R.2
-
256
-
-
33748208668
-
C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells
-
Gomis RR, Alarcon C, Nadal C, Van Poznak C, Massague J. C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells. Cancer Cell 2006; 10: 203-214.
-
(2006)
Cancer Cell
, vol.10
, pp. 203-214
-
-
Gomis, R.R.1
Alarcon, C.2
Nadal, C.3
van Poznak, C.4
Massague, J.5
-
257
-
-
33748075143
-
A FoxO-Smad synexpression group in human keratinocytes
-
Gomis RR, Alarcon C, He W, et al. A FoxO-Smad synexpression group in human keratinocytes. Proc Natl Acad Sci USA 2006; 103: 12747-12752.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12747-12752
-
-
Gomis, R.R.1
Alarcon, C.2
He, W.3
-
258
-
-
0037039312
-
CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling
-
Zhu S, Yoon K, Sterneck E, Johnson PF, Smart RC. CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling. Proc Natl Acad Sci USA 2002; 99: 207-212.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 207-212
-
-
Zhu, S.1
Yoon, K.2
Sterneck, E.3
Johnson, P.F.4
Smart, R.C.5
-
259
-
-
4344714027
-
Cell cycle-dependent phosphorylation of C/EBPbeta mediates oncogenic cooperativity between C/EBPbeta and H-RasV12
-
Shuman JD, Sebastian T, Kaldis P, et al. Cell cycle-dependent phosphorylation of C/EBPbeta mediates oncogenic cooperativity between C/EBPbeta and H-RasV12. Mol Cell Biol 2004; 24: 7380-7391.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7380-7391
-
-
Shuman, J.D.1
Sebastian, T.2
Kaldis, P.3
-
260
-
-
33846319709
-
Decreased survival of C/EBP beta-deficient keratinocytes is due to aberrant regulation of p53 levels and function
-
Yoon K, Zhu S, Ewing SJ, Smart RC. Decreased survival of C/EBP beta-deficient keratinocytes is due to aberrant regulation of p53 levels and function. Oncogene 2007; 26: 360-367.
-
(2007)
Oncogene
, vol.26
, pp. 360-367
-
-
Yoon, K.1
Zhu, S.2
Ewing, S.J.3
Smart, R.C.4
-
261
-
-
54049144611
-
C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf)
-
Ewing SJ, Zhu S, Zhu F, House JS, Smart RC. C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf). Cell Death Differ 2008; 15: 1734-1744.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1734-1744
-
-
Ewing, S.J.1
Zhu, S.2
Zhu, F.3
House, J.S.4
Smart, R.C.5
-
262
-
-
0038322020
-
Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function
-
Choy L, Derynck R. Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function. J Biol Chem 2003; 278: 9609-9619.
-
(2003)
J Biol Chem
, vol.278
, pp. 9609-9619
-
-
Choy, L.1
Derynck, R.2
-
263
-
-
0035984289
-
Interaction between TGFbeta signaling proteins and C/EBP controls basal and Tat-mediated transcription of HIV-1 LTR in astrocytes
-
Coyle-Rink J, Sweet T, Abraham S, et al. Interaction between TGFbeta signaling proteins and C/EBP controls basal and Tat-mediated transcription of HIV-1 LTR in astrocytes. Virology 2002; 299: 240-247.
-
(2002)
Virology
, vol.299
, pp. 240-247
-
-
Coyle-Rink, J.1
Sweet, T.2
Abraham, S.3
-
264
-
-
0035816686
-
Smad proteins suppress CCAAT/enhancer-binding protein (C/EBP) beta-and STAT3-mediated transcriptional activation of the haptoglobin promoter
-
Zauberman A, Lapter S, Zipori D. Smad proteins suppress CCAAT/enhancer-binding protein (C/EBP) beta-and STAT3-mediated transcriptional activation of the haptoglobin promoter. J Biol Chem 2001; 276: 24719-24725.
-
(2001)
J Biol Chem
, vol.276
, pp. 24719-24725
-
-
Zauberman, A.1
Lapter, S.2
Zipori, D.3
-
265
-
-
67649202062
-
Forkhead box O-class 1 and forkhead box G1 as prognostic markers for bladder cancer
-
Kim TH, Jo SW, Lee YS, et al. Forkhead box O-class 1 and forkhead box G1 as prognostic markers for bladder cancer. J Korean Med Sci 2009; 24: 468-473.
-
(2009)
J Korean Med Sci
, vol.24
, pp. 468-473
-
-
Kim, T.H.1
Jo, S.W.2
Lee, Y.S.3
-
266
-
-
0345824722
-
Foxg1 suppresses early cortical cell fate
-
Hanashima C, Li SC, Shen L, Lai E, Fishell G. Foxg1 suppresses early cortical cell fate. Science 2004; 303: 56-59.
-
(2004)
Science
, vol.303
, pp. 56-59
-
-
Hanashima, C.1
Li, S.C.2
Shen, L.3
Lai, E.4
Fishell, G.5
-
267
-
-
70349973752
-
Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer
-
Chan DW, Liu VW, To RM, et al. Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer. Br J Cancer 2009; 101: 1433-1443.
-
(2009)
Br J Cancer
, vol.101
, pp. 1433-1443
-
-
Chan, D.W.1
Liu, V.W.2
To, R.M.3
-
268
-
-
37349099564
-
Generation of Cajal-Retzius neurons in mouse forebrain is regulated by transforming growth factor beta-Fox signaling pathways
-
Siegenthaler JA, Miller MW. Generation of Cajal-Retzius neurons in mouse forebrain is regulated by transforming growth factor beta-Fox signaling pathways. Dev Biol 2008 313: 35-46
-
(2008)
Dev Biol
, vol.313
, pp. 35-46
-
-
Siegenthaler, J.A.1
Miller, M.W.2
-
269
-
-
37349016202
-
Kruppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis
-
Nandan MO, McConnell BB, Ghaleb AM, et al. Kruppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis. Gastroenterology. 2008; 134: 120-130.
-
(2008)
Gastroenterology
, vol.134
, pp. 120-130
-
-
Nandan, M.O.1
McConnell, B.B.2
Ghaleb, A.M.3
-
270
-
-
0037179848
-
A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer
-
Chen C, Bhalala HV, Qiao H, Dong JT. A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer. Oncogene 2002; 21: 6567-6572.
-
(2002)
Oncogene
, vol.21
, pp. 6567-6572
-
-
Chen, C.1
Bhalala, H.V.2
Qiao, H.3
Dong, J.T.4
-
271
-
-
1842425769
-
Intestinal tumor progression is associated with altered function of KLF5
-
Bateman NW, Tan D, Pestell RG, Black JD, Black AR. Intestinal tumor progression is associated with altered function of KLF5. J Biol Chem 2004; 279: 12093-12101.
-
(2004)
J Biol Chem
, vol.279
, pp. 12093-12101
-
-
Bateman, N.W.1
Tan, D.2
Pestell, R.G.3
Black, J.D.4
Black, A.R.5
-
272
-
-
65249114297
-
Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification
-
Guo P, Dong XY, Zhang X, et al. Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification. J Biol Chem 2009; 284: 6071-6078.
-
(2009)
J Biol Chem
, vol.284
, pp. 6071-6078
-
-
Guo, P.1
Dong, X.Y.2
Zhang, X.3
-
273
-
-
67650555438
-
Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells
-
Guo P, Zhao KW, Dong XY, Sun X, Dong JT. Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells. J Biol Chem 2009; 284: 18184-18193.
-
(2009)
J Biol Chem
, vol.284
, pp. 18184-18193
-
-
Guo, P.1
Zhao, K.W.2
Dong, X.Y.3
Sun, X.4
Dong, J.T.5
-
274
-
-
70350502092
-
Opposing effects of KLF5 on the transcription of MYC in epithelial proliferation in the context of transforming growth factor beta
-
Guo P, Dong XY, Zhao K, Sun X, Li Q, Dong JT. Opposing effects of KLF5 on the transcription of MYC in epithelial proliferation in the context of transforming growth factor beta. J Biol Chem 2009; 284: 28243-28252.
-
(2009)
J Biol Chem
, vol.284
, pp. 28243-28252
-
-
Guo, P.1
Dong, X.Y.2
Zhao, K.3
Sun, X.4
Li, Q.5
Dong, J.T.6
-
276
-
-
53149108993
-
TGFbeta1, TNFalpha, and insulin signaling crosstalk in regulation of the rat cholesterol 7alpha-hydroxylase gene expression
-
Li T, Ma H, Chiang JY. TGFbeta1, TNFalpha, and insulin signaling crosstalk in regulation of the rat cholesterol 7alpha-hydroxylase gene expression. J Lipid Res 2008; 49: 1981-1989.
-
(2008)
J Lipid Res
, vol.49
, pp. 1981-1989
-
-
Li, T.1
Ma, H.2
Chiang, J.Y.3
-
277
-
-
0033869876
-
Translational control of C/EBPalpha and C/EBPbeta isoform expression
-
Calkhoven CF, Muller C, Leutz A. Translational control of C/EBPalpha and C/EBPbeta isoform expression. Genes Dev 2000; 14: 1920-1932.
-
(2000)
Genes Dev
, vol.14
, pp. 1920-1932
-
-
Calkhoven, C.F.1
Muller, C.2
Leutz, A.3
-
278
-
-
34547133494
-
The C/EBP family of transcription factors: A paradigm for interaction between gene expression and proliferation control
-
Nerlov C. The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control. Trends Cell Biol 2007; 17: 318-324.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 318-324
-
-
Nerlov, C.1
-
279
-
-
33751510219
-
Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression
-
Yamasaki H, Sada A, Iwata T, et al. Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression. Development 2006; 133: 4233-4243.
-
(2006)
Development
, vol.133
, pp. 4233-4243
-
-
Yamasaki, H.1
Sada, A.2
Iwata, T.3
-
280
-
-
0032504613
-
Hepatocytes deficient in CCAAT/enhancer binding protein alpha (C/EBP alpha) exhibit both hepatocyte and biliary epithelial cell character
-
Tomizawa M, Garfield S, Factor V, Xanthopoulos KG. Hepatocytes deficient in CCAAT/enhancer binding protein alpha (C/EBP alpha) exhibit both hepatocyte and biliary epithelial cell character. Biochem Biophys Res Commun 1998; 249: 1-5.
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 1-5
-
-
Tomizawa, M.1
Garfield, S.2
Factor, V.3
Xanthopoulos, K.G.4
-
281
-
-
0035896598
-
A nucleoprotein complex containing CCAAT/enhancer-binding protein beta interacts with an insulin response sequence in the insulin-like growth factor-binding protein-1 gene and contributes to insulin-regulated gene expression
-
Ghosh AK, Lacson R, Liu P, et al. A nucleoprotein complex containing CCAAT/enhancer-binding protein beta interacts with an insulin response sequence in the insulin-like growth factor-binding protein-1 gene and contributes to insulin-regulated gene expression. J Biol Chem 2001; 276: 8507-8515.
-
(2001)
J Biol Chem
, vol.276
, pp. 8507-8515
-
-
Ghosh, A.K.1
Lacson, R.2
Liu, P.3
-
282
-
-
34547824172
-
Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development
-
Sekine K, Chen YR, Kojima N, Ogata K, Fukamizu A, Miyajima A. Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development. Embo J 2007; 26: 3607-3615.
-
(2007)
Embo J
, vol.26
, pp. 3607-3615
-
-
Sekine, K.1
Chen, Y.R.2
Kojima, N.3
Ogata, K.4
Fukamizu, A.5
Miyajima, A.6
-
283
-
-
0028980389
-
C/EBP alpha: A critical regulator of genes governing integrative metabolic processes
-
Darlington GJ, Wang N, Hanson RW. C/EBP alpha: a critical regulator of genes governing integrative metabolic processes. Curr Opin Genet Dev 1995; 5: 565-570.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 565-570
-
-
Darlington, G.J.1
Wang, N.2
Hanson, R.W.3
-
284
-
-
2642549921
-
Liver-enriched transcription factors in liver function and development. Part II: The C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation
-
Schrem H, Klempnauer J, Borlak J. Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation. Pharmacol Rev 2004; 56: 291-330.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 291-330
-
-
Schrem, H.1
Klempnauer, J.2
Borlak, J.3
-
285
-
-
41549153181
-
C/EBPs: Recipients of extracellular signals through proteome modulation
-
Nerlov C. C/EBPs: recipients of extracellular signals through proteome modulation. Curr Opin Cell Biol 2008; 20: 180-185.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 180-185
-
-
Nerlov, C.1
-
286
-
-
51849147067
-
Role of FoxO1 activation in MDR1 expression in adriamycin-resistant breast cancer cells
-
Han CY, Cho KB, Choi HS, Han HK, Kang KW. Role of FoxO1 activation in MDR1 expression in adriamycin-resistant breast cancer cells. Carcinogenesis 2008; 29: 1837-1844.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1837-1844
-
-
Han, C.Y.1
Cho, K.B.2
Choi, H.S.3
Han, H.K.4
Kang, K.W.5
-
287
-
-
0037036407
-
Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein beta in differentiating human endometrial stromal cells
-
Christian M, Zhang X, Schneider-Merck T, et al. Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein beta in differentiating human endometrial stromal cells. J Biol Chem 2002; 277: 20825-20832.
-
(2002)
J Biol Chem
, vol.277
, pp. 20825-20832
-
-
Christian, M.1
Zhang, X.2
Schneider-Merck, T.3
-
288
-
-
0030928627
-
Progesterone-dependent decidualization of the human endometrium is mediated by cAMP
-
Brar AK, Frank GR, Kessler CA, Cedars MI, Handwerger S. Progesterone-dependent decidualization of the human endometrium is mediated by cAMP. Endocrine 1997; 6: 301-307.
-
(1997)
Endocrine
, vol.6
, pp. 301-307
-
-
Brar, A.K.1
Frank, G.R.2
Kessler, C.A.3
Cedars, M.I.4
Handwerger, S.5
-
289
-
-
0033305291
-
Progesterone receptor regulates decidual prolactin expression in differentiating human endometrial stromal cells
-
Brosens JJ, Hayashi N, White JO. Progesterone receptor regulates decidual prolactin expression in differentiating human endometrial stromal cells. Endocrinology 1999; 140: 4809-4820.
-
(1999)
Endocrinology
, vol.140
, pp. 4809-4820
-
-
Brosens, J.J.1
Hayashi, N.2
White, J.O.3
-
290
-
-
0031047405
-
Activated protein kinase A is required for differentiation-dependent transcription of the decidual prolactin gene in human endometrial stromal cells
-
Telgmann R, Maronde E, Tasken K, Gellersen B. Activated protein kinase A is required for differentiation-dependent transcription of the decidual prolactin gene in human endometrial stromal cells. Endocrinology 1997; 138: 929-937.
-
(1997)
Endocrinology
, vol.138
, pp. 929-937
-
-
Telgmann, R.1
Maronde, E.2
Tasken, K.3
Gellersen, B.4
-
291
-
-
0033609858
-
CCAAT/enhancer-binding proteins are mediators in the protein kinase A-dependent activation of the decidual prolactin promoter
-
Pohnke Y, Kempf R, Gellersen B. CCAAT/enhancer-binding proteins are mediators in the protein kinase A-dependent activation of the decidual prolactin promoter. J Biol Chem 1999; 274: 24808-24818.
-
(1999)
J Biol Chem
, vol.274
, pp. 24808-24818
-
-
Pohnke, Y.1
Kempf, R.2
Gellersen, B.3
-
292
-
-
73849111344
-
Forkhead transcription factor Foxo1 is essential for adipocyte differentiation
-
Munekata K, Sakamoto K. Forkhead transcription factor Foxo1 is essential for adipocyte differentiation. In Vitro Cell Dev Biol Anim 2009; 45: 642-651.
-
(2009)
In Vitro Cell Dev Biol Anim
, vol.45
, pp. 642-651
-
-
Munekata, K.1
Sakamoto, K.2
-
294
-
-
30944466045
-
A role for Hox A5 in regulating angiogenesis and vascular patterning
-
Rhoads K, Arderiu G, Charboneau A, Hansen SL, Hoffman W, Boudreau N. A role for Hox A5 in regulating angiogenesis and vascular patterning. Lymphat Res Biol 2005; 3: 240-252.
-
(2005)
Lymphat Res Biol
, vol.3
, pp. 240-252
-
-
Rhoads, K.1
Arderiu, G.2
Charboneau, A.3
Hansen, S.L.4
Hoffman, W.5
Boudreau, N.6
-
295
-
-
0027515736
-
Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata
-
Giudice LC, Irwin JC, Dsupin BA, et al. Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata. Hum Reprod 1993; 8: 1796-806.
-
(1993)
Hum Reprod
, vol.8
, pp. 1796-1806
-
-
Giudice, L.C.1
Irwin, J.C.2
Dsupin, B.A.3
-
296
-
-
0037235335
-
Regulation of insulin-like growth factor binding protein-1 promoter activity by FKHR and HOXA10 in primate endometrial cells
-
Kim JJ, Taylor HS, Akbas GE, et al. Regulation of insulin-like growth factor binding protein-1 promoter activity by FKHR and HOXA10 in primate endometrial cells. Biol Reprod 2003; 68: 24-30.
-
(2003)
Biol Reprod
, vol.68
, pp. 24-30
-
-
Kim, J.J.1
Taylor, H.S.2
Akbas, G.E.3
-
297
-
-
0029793280
-
Mechanisms of reduced fertility in Hoxa-10 mutant mice: Uterine homeosis and loss of maternal Hoxa-10 expression
-
Benson GV, Lim H, Paria BC, Satokata I, Dey SK, Maas RL. Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression. Development 1996; 122: 2687-2696.
-
(1996)
Development
, vol.122
, pp. 2687-2696
-
-
Benson, G.V.1
Lim, H.2
Paria, B.C.3
Satokata, I.4
Dey, S.K.5
Maas, R.L.6
-
298
-
-
0030778154
-
Insulin-like growth factor binding protein-1: Recent findings and new directions
-
Lee PD, Giudice LC, Conover CA, Powell DR. Insulin-like growth factor binding protein-1: recent findings and new directions. Proc Soc Exp Biol Med 1997; 216: 319-357.
-
(1997)
Proc Soc Exp Biol Med
, vol.216
, pp. 319-357
-
-
Lee, P.D.1
Giudice, L.C.2
Conover, C.A.3
Powell, D.R.4
-
299
-
-
0034039896
-
Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins
-
Schneider MR, Lahm H, Wu M, Hoeflich A, Wolf E. Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins. Faseb J 2000; 14: 629-640.
-
(2000)
Faseb J
, vol.14
, pp. 629-640
-
-
Schneider, M.R.1
Lahm, H.2
Wu, M.3
Hoeflich, A.4
Wolf, E.5
-
300
-
-
0030999590
-
Liver-specific expression of human insulin-like growth factor binding protein-1 in transgenic mice: Repercussions on reproduction, ante-and perinatal mortality and postnatal growth
-
Gay E, Seurin D, Babajko S, Doublier S, Cazillis M, Binoux M. Liver-specific expression of human insulin-like growth factor binding protein-1 in transgenic mice: repercussions on reproduction, ante-and perinatal mortality and postnatal growth. Endocrinology 1997; 138: 2937-2947.
-
(1997)
Endocrinology
, vol.138
, pp. 2937-2947
-
-
Gay, E.1
Seurin, D.2
Babajko, S.3
Doublier, S.4
Cazillis, M.5
Binoux, M.6
-
301
-
-
0036714077
-
Hoxa5 overexpression correlates with IGFBP1 upregulation and postnatal dwarfism: Evidence for an interaction between Hoxa5 and Forkhead box transcription factors
-
Foucher I, Volovitch M, Frain M, et al. Hoxa5 overexpression correlates with IGFBP1 upregulation and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead box transcription factors. Development 2002; 129: 4065-4074.
-
(2002)
Development
, vol.129
, pp. 4065-4074
-
-
Foucher, I.1
Volovitch, M.2
Frain, M.3
-
302
-
-
34948872466
-
Transcriptional cross talk between the forkhead transcription factor forkhead box O1A and the progesterone receptor coordinates cell cycle regulation and differentiation in human endometrial stromal cells
-
Takano M, Lu Z, Goto T, et al. Transcriptional cross talk between the forkhead transcription factor forkhead box O1A and the progesterone receptor coordinates cell cycle regulation and differentiation in human endometrial stromal cells. Mol Endocrinol 2007; 21: 2334-2349.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 2334-2349
-
-
Takano, M.1
Lu, Z.2
Goto, T.3
-
303
-
-
41549098778
-
The regulation and function of the forkhead transcription factor, Forkhead box O1, is dependent on the progesterone receptor in endometrial carcinoma
-
Ward EC, Hoekstra AV, Blok LJ, et al. The regulation and function of the forkhead transcription factor, Forkhead box O1, is dependent on the progesterone receptor in endometrial carcinoma. Endocrinology 2008; 149: 1942-1950.
-
(2008)
Endocrinology
, vol.149
, pp. 1942-1950
-
-
Ward, E.C.1
Hoekstra, A.V.2
Blok, L.J.3
-
304
-
-
0033546192
-
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin¬like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
-
Guo S, Rena G, Cichy S, He X, Cohen P, Unterman T. Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin¬like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. J Biol Chem 1999; 274: 17184-17192.
-
(1999)
J Biol Chem
, vol.274
, pp. 17184-17192
-
-
Guo, S.1
Rena, G.2
Cichy, S.3
He, X.4
Cohen, P.5
Unterman, T.6
-
305
-
-
25144495477
-
Role of FOXO1A in the regulation of insulin-like growth factor-binding protein-1 in human endometrial cells: Interaction with progesterone receptor
-
Kim JJ, Buzzio OL, Li S, Lu Z. Role of FOXO1A in the regulation of insulin-like growth factor-binding protein-1 in human endometrial cells: interaction with progesterone receptor. Biol Reprod 2005; 73: 833-839.
-
(2005)
Biol Reprod
, vol.73
, pp. 833-839
-
-
Kim, J.J.1
Buzzio, O.L.2
Li, S.3
Lu, Z.4
-
306
-
-
34347384383
-
Constitutively active FOXO1a and a DNA-binding domain mutant exhibit distinct co-regulatory functions to enhance progesterone receptor A activity
-
Rudd MD, Gonzalez-Robayna I, Hernandez-Gonzalez I, Weigel NL, Bingman WE, 3rd, Richards JS. Constitutively active FOXO1a and a DNA-binding domain mutant exhibit distinct co-regulatory functions to enhance progesterone receptor A activity. J Mol Endocrinol 2007; 38: 673-690.
-
(2007)
J Mol Endocrinol
, vol.38
, pp. 673-690
-
-
Rudd, M.D.1
Gonzalez-Robayna, I.2
Hernandez-Gonzalez, I.3
Weigel, N.L.4
Bingman, W.E.5
Richards, J.S.6
-
307
-
-
18844432308
-
Adiponectin and adiponectin receptors
-
Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev 2005; 26: 439-451.
-
(2005)
Endocr Rev
, vol.26
, pp. 439-451
-
-
Kadowaki, T.1
Yamauchi, T.2
-
308
-
-
17544382289
-
AdipoQ is a novel adipose-specific gene dysregulated in obesity
-
Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996; 271: 10697-10703.
-
(1996)
J Biol Chem
, vol.271
, pp. 10697-10703
-
-
Hu, E.1
Liang, P.2
Spiegelman, B.M.3
-
309
-
-
33845985335
-
SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex
-
Qiao L, Shao J. SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex. J Biol Chem 2006; 281: 39915-39924.
-
(2006)
J Biol Chem
, vol.281
, pp. 39915-39924
-
-
Qiao, L.1
Shao, J.2
-
310
-
-
70350497395
-
Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML
-
Bereshchenko O, Mancini E, Moore S, et al. Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML. Cancer Cell 2009; 16: 390-400.
-
(2009)
Cancer Cell
, vol.16
, pp. 390-400
-
-
Bereshchenko, O.1
Mancini, E.2
Moore, S.3
-
311
-
-
0035374460
-
Growth hormone regulates phosphorylation and function of CCAAT/enhancer-binding protein beta by modulating Akt and glycogen synthase kinase-3
-
Piwien-Pilipuk G, Van Mater D, Ross SE, MacDougald OA, Schwartz J. Growth hormone regulates phosphorylation and function of CCAAT/enhancer-binding protein beta by modulating Akt and glycogen synthase kinase-3. J Biol Chem 2001; 276: 19664-19671.
-
(2001)
J Biol Chem
, vol.276
, pp. 19664-19671
-
-
Piwien-Pilipuk, G.1
van Mater, D.2
Ross, S.E.3
Macdougald, O.A.4
Schwartz, J.5
-
312
-
-
14644425319
-
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia
-
Ren R. Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat Rev Cancer 2005; 5: 172-183.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 172-183
-
-
Ren, R.1
-
313
-
-
33749524667
-
Dynamic modeling of imatinib-treated chronic myeloid leukemia: Functional insights and clinical implications
-
Roeder I, Horn M, Glauche I, Hochhaus A, Mueller MC, Loeffler M. Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications. Nat Med 2006; 12: 1181-1184.
-
(2006)
Nat Med
, vol.12
, pp. 1181-1184
-
-
Roeder, I.1
Horn, M.2
Glauche, I.3
Hochhaus, A.4
Mueller, M.C.5
Loeffler, M.6
-
314
-
-
76249087423
-
TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia
-
Naka K, Hoshii T, Muraguchi T, et al. TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia. Nature; 463: 676-680.
-
Nature
, vol.463
, pp. 676-680
-
-
Naka, K.1
Hoshii, T.2
Muraguchi, T.3
-
315
-
-
0242580872
-
Convergence of peroxisome proliferator-activated receptor gamma and Foxo1 signaling pathways
-
Dowell P, Otto TC, Adi S, Lane MD. Convergence of peroxisome proliferator-activated receptor gamma and Foxo1 signaling pathways. J Biol Chem 2003; 278: 45485-45491.
-
(2003)
J Biol Chem
, vol.278
, pp. 45485-45491
-
-
Dowell, P.1
Otto, T.C.2
Adi, S.3
Lane, M.D.4
-
316
-
-
0037216526
-
AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR
-
Li P, Lee H, Guo S, Unterman TG, Jenster G, Bai W. AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR. Mol Cell Biol 2003; 23: 104-118.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 104-118
-
-
Li, P.1
Lee, H.2
Guo, S.3
Unterman, T.G.4
Jenster, G.5
Bai, W.6
-
317
-
-
0035823576
-
Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family
-
Schuur ER, Loktev AV, Sharma M, Sun Z, Roth RA, Weigel RJ. Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family. J Biol Chem 2001; 276: 33554-33560.
-
(2001)
J Biol Chem
, vol.276
, pp. 33554-33560
-
-
Schuur, E.R.1
Loktev, A.V.2
Sharma, M.3
Sun, Z.4
Roth, R.A.5
Weigel, R.J.6
-
318
-
-
66449089902
-
FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes
-
Fan W, Imamura T, Sonoda N, et al. FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes. J Biol Chem 2009; 284: 12188-12197.
-
(2009)
J Biol Chem
, vol.284
, pp. 12188-12197
-
-
Fan, W.1
Imamura, T.2
Sonoda, N.3
-
319
-
-
0042405041
-
Peroxisome proliferator-activated receptors (PPARS): Regulators of gene expression in heart and skeletal muscle
-
Gilde AJ, Van Bilsen M. Peroxisome proliferator-activated receptors (PPARS): regulators of gene expression in heart and skeletal muscle. Acta Physiol Scand 2003; 178: 425-434.
-
(2003)
Acta Physiol Scand
, vol.178
, pp. 425-434
-
-
Gilde, A.J.1
van Bilsen, M.2
-
320
-
-
33746017379
-
FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity
-
Armoni M, Harel C, Karni S, et al. FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity. J Biol Chem 2006; 281: 19881-19891.
-
(2006)
J Biol Chem
, vol.281
, pp. 19881-19891
-
-
Armoni, M.1
Harel, C.2
Karni, S.3
-
321
-
-
64049089450
-
SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma
-
Wang F, Tong Q. SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma. Mol Biol Cell 2009; 20: 801-808.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 801-808
-
-
Wang, F.1
Tong, Q.2
-
322
-
-
33747047885
-
Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action
-
Samuel VT, Choi CS, Phillips TG, et al. Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action. Diabetes 2006; 55: 2042-2050.
-
(2006)
Diabetes
, vol.55
, pp. 2042-2050
-
-
Samuel, V.T.1
Choi, C.S.2
Phillips, T.G.3
-
323
-
-
66649115077
-
FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue
-
Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM. FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue. Diabetes 2009; 58: 1275-1282.
-
(2009)
Diabetes
, vol.58
, pp. 1275-1282
-
-
Kim, J.J.1
Li, P.2
Huntley, J.3
Chang, J.P.4
Arden, K.C.5
Olefsky, J.M.6
-
324
-
-
0033593461
-
Signaling mechanisms that regulate glucose transport
-
Czech MP, Corvera S. Signaling mechanisms that regulate glucose transport. J Biol Chem 1999; 274: 1865-1868.
-
(1999)
J Biol Chem
, vol.274
, pp. 1865-1868
-
-
Czech, M.P.1
Corvera, S.2
-
325
-
-
33947378695
-
Transcriptional regulation of the GLUT4 gene: From PPAR-gamma and FOXO1 to FFA and inflammation
-
Armoni M, Harel C, Karnieli E. Transcriptional regulation of the GLUT4 gene: from PPAR-gamma and FOXO1 to FFA and inflammation. Trends Endocrinol Metab 2007; 18: 100-107.
-
(2007)
Trends Endocrinol Metab
, vol.18
, pp. 100-107
-
-
Armoni, M.1
Harel, C.2
Karnieli, E.3
-
326
-
-
0036846196
-
PAX3/forkhead homolog in rhabdomyosarcoma oncoprotein activates glucose transporter 4 gene expression in vivo and in vitro
-
Armoni M, Quon MJ, Maor G, et al. PAX3/forkhead homolog in rhabdomyosarcoma oncoprotein activates glucose transporter 4 gene expression in vivo and in vitro. J Clin Endocrinol Metab 2002; 87: 5312-5324.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 5312-5324
-
-
Armoni, M.1
Quon, M.J.2
Maor, G.3
-
327
-
-
0037432191
-
A forkhead transcription factor FKHR up-regulates lipoprotein lipase expression in skeletal muscle
-
Kamei Y, Mizukami J, Miura S, et al. A forkhead transcription factor FKHR up-regulates lipoprotein lipase expression in skeletal muscle. FEBS Lett 2003; 536: 232-236.
-
(2003)
FEBS Lett
, vol.536
, pp. 232-236
-
-
Kamei, Y.1
Mizukami, J.2
Miura, S.3
-
328
-
-
17144428529
-
FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and -independent mechanisms
-
Bastie CC, Nahle Z, McLoughlin T, et al. FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and -independent mechanisms. J Biol Chem 2005; 280: 14222-14229.
-
(2005)
J Biol Chem
, vol.280
, pp. 14222-14229
-
-
Bastie, C.C.1
Nahle, Z.2
McLoughlin, T.3
-
329
-
-
0035139016
-
The role of PPAR-gamma in macrophage differentiation and cholesterol uptake
-
Moore KJ, Rosen ED, Fitzgerald ML, et al. The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. Nat Med 2001; 7: 41-47.
-
(2001)
Nat Med
, vol.7
, pp. 41-47
-
-
Moore, K.J.1
Rosen, E.D.2
Fitzgerald, M.L.3
-
330
-
-
0035132330
-
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
-
Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 2001; 7: 48-52.
-
(2001)
Nat Med
, vol.7
, pp. 48-52
-
-
Chawla, A.1
Barak, Y.2
Nagy, L.3
Liao, D.4
Tontonoz, P.5
Evans, R.M.6
-
331
-
-
33846878069
-
PPAR{alpha} mediates the hypolipidemic action of fibrates by antagonizing FoxO1
-
Qu S, Su D, Altomonte J, et al. PPAR{alpha} mediates the hypolipidemic action of fibrates by antagonizing FoxO1. Am J Physiol Endocrinol Metab 2007; 292: E421-E434.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
, pp. 421-434
-
-
Qu, S.1
Su, D.2
Altomonte, J.3
-
332
-
-
75149152919
-
Metabolism of Very-Low-Density Lipoprotein and Low-Density Lipoprotein Containing Apolipoprotein C-III and Not Other Small Apolipoproteins
-
Mendivil CO, Zheng C, Furtado J, Lel J, Sacks FM. Metabolism of Very-Low-Density Lipoprotein and Low-Density Lipoprotein Containing Apolipoprotein C-III and Not Other Small Apolipoproteins. Arterioscler Thromb Vasc Biol 2010; 30: 239-245.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 239-245
-
-
Mendivil, C.O.1
Zheng, C.2
Furtado, J.3
Lel, J.4
Sacks, F.M.5
-
333
-
-
15244339047
-
Foxo1 mediates insulin action on apoC-III and triglyceride metabolism
-
Altomonte J, Cong L, Harbaran S, et al. Foxo1 mediates insulin action on apoC-III and triglyceride metabolism. J Clin Invest 2004; 114: 1493-1503.
-
(2004)
J Clin Invest
, vol.114
, pp. 1493-1503
-
-
Altomonte, J.1
Cong, L.2
Harbaran, S.3
-
334
-
-
0038242819
-
TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
-
Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 2003; 300: 1574-1577.
-
(2003)
Science
, vol.300
, pp. 1574-1577
-
-
Du, K.1
Herzig, S.2
Kulkarni, R.N.3
Montminy, M.4
-
335
-
-
2442701392
-
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
-
Koo SH, Satoh H, Herzig S, et al. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat Med 2004; 10: 530-534.
-
(2004)
Nat Med
, vol.10
, pp. 530-534
-
-
Koo, S.H.1
Satoh, H.2
Herzig, S.3
-
336
-
-
34547956322
-
Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta
-
Degenhardt T, Saramaki A, Malinen M, et al. Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta. J Mol Biol 2007; 372: 341-355.
-
(2007)
J Mol Biol
, vol.372
, pp. 341-355
-
-
Degenhardt, T.1
Saramaki, A.2
Malinen, M.3
-
337
-
-
0037135623
-
Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta
-
Muoio DM, MacLean PS, Lang DB, et al. Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. J Biol Chem 2002; 277: 26089-26097.
-
(2002)
J Biol Chem
, vol.277
, pp. 26089-26097
-
-
Muoio, D.M.1
Maclean, P.S.2
Lang, D.B.3
-
338
-
-
34547673326
-
Regulatory functions of PPARbeta in metabolism: Implications for the treatment of metabolic syndrome
-
Grimaldi PA. Regulatory functions of PPARbeta in metabolism: implications for the treatment of metabolic syndrome. Biochim Biophys Acta 2007; 1771: 983-990.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 983-990
-
-
Grimaldi, P.A.1
-
339
-
-
33646792244
-
Peroxisome proliferator-activated receptor delta (PPARdelta), a novel target site for drug discovery in metabolic syndrome
-
Takahashi S, Tanaka T, Kodama T, Sakai J. Peroxisome proliferator-activated receptor delta (PPARdelta), a novel target site for drug discovery in metabolic syndrome. Pharmacol Res 2006; 53: 501-507.
-
(2006)
Pharmacol Res
, vol.53
, pp. 501-507
-
-
Takahashi, S.1
Tanaka, T.2
Kodama, T.3
Sakai, J.4
-
340
-
-
47249119658
-
CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress
-
Nahle Z, Hsieh M, Pietka T, et al. CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress. J Biol Chem 2008; 283: 14317-14326.
-
(2008)
J Biol Chem
, vol.283
, pp. 14317-14326
-
-
Nahle, Z.1
Hsieh, M.2
Pietka, T.3
-
341
-
-
52649174345
-
Pharmacological activation of PPARbeta promotes rapid and calcineurin-dependent fiber remodeling and angiogenesis in mouse skeletal muscle
-
Gaudel C, Schwartz C, Giordano C, Abumrad NA, Grimaldi PA. Pharmacological activation of PPARbeta promotes rapid and calcineurin-dependent fiber remodeling and angiogenesis in mouse skeletal muscle. Am J Physiol Endocrinol Metab 2008; 295: E297-E304.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, pp. 297-304
-
-
Gaudel, C.1
Schwartz, C.2
Giordano, C.3
Abumrad, N.A.4
Grimaldi, P.A.5
-
342
-
-
34547865385
-
PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle
-
Constantin D, Constantin-Teodosiu D, Layfield R, Tsintzas K, Bennett AJ, Greenhaff PL. PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle. J Physiol 2007; 583: 381-390.
-
(2007)
J Physiol
, vol.583
, pp. 381-390
-
-
Constantin, D.1
Constantin-Teodosiu, D.2
Layfield, R.3
Tsintzas, K.4
Bennett, A.J.5
Greenhaff, P.L.6
-
343
-
-
0034518420
-
The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
-
Repa JJ, Mangelsdorf DJ. The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Annu Rev Cell Dev Biol 2000; 16: 459-481.
-
(2000)
Annu Rev Cell Dev Biol
, vol.16
, pp. 459-481
-
-
Repa, J.J.1
Mangelsdorf, D.J.2
-
344
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
-
Peet DJ, Turley SD, Ma W, et al. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 1998; 93: 693-704.
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
-
345
-
-
0037058995
-
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
-
Yu L, Hammer RE, Li-Hawkins J, et al. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci USA 2002; 99: 16237-16242.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16237-16242
-
-
Yu, L.1
Hammer, R.E.2
Li-Hawkins, J.3
-
346
-
-
34547652884
-
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE
-
Bradley MN, Hong C, Chen M, et al. Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. J Clin Invest 2007; 117: 2337-2346.
-
(2007)
J Clin Invest
, vol.117
, pp. 2337-2346
-
-
Bradley, M.N.1
Hong, C.2
Chen, M.3
-
347
-
-
42549086338
-
Regulation of SREBP1c gene expression in skeletal muscle: Role of retinoid X receptor/liver X receptor and forkhead-O1 transcription factor
-
Kamei Y, Miura S, Suganami T, et al. Regulation of SREBP1c gene expression in skeletal muscle: role of retinoid X receptor/liver X receptor and forkhead-O1 transcription factor. Endocrinology 2008; 149: 2293-2305.
-
(2008)
Endocrinology
, vol.149
, pp. 2293-2305
-
-
Kamei, Y.1
Miura, S.2
Suganami, T.3
-
348
-
-
42249111748
-
The roles of nuclear receptors CAR and PXR in hepatic energy metabolism
-
Konno Y, Negishi M, Kodama S. The roles of nuclear receptors CAR and PXR in hepatic energy metabolism. Drug Metab Pharmacokinet 2008; 23: 8-13.
-
(2008)
Drug Metab Pharmacokinet
, vol.23
, pp. 8-13
-
-
Konno, Y.1
Negishi, M.2
Kodama, S.3
-
350
-
-
33744948052
-
A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway
-
Zhou J, Zhai Y, Mu Y, et al. A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway. J Biol Chem 2006; 281: 15013-15020.
-
(2006)
J Biol Chem
, vol.281
, pp. 15013-15020
-
-
Zhou, J.1
Zhai, Y.2
Mu, Y.3
-
351
-
-
35748972683
-
Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene
-
Kodama S, Moore R, Yamamoto Y, Negishi M. Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene. Biochem J 2007; 407: 373-381.
-
(2007)
Biochem J
, vol.407
, pp. 373-381
-
-
Kodama, S.1
Moore, R.2
Yamamoto, Y.3
Negishi, M.4
-
352
-
-
4444246000
-
Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes
-
Kodama S, Koike C, Negishi M, Yamamoto Y. Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes. Mol Cell Biol 2004; 24: 7931-7940.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7931-7940
-
-
Kodama, S.1
Koike, C.2
Negishi, M.3
Yamamoto, Y.4
-
353
-
-
33847240106
-
(Far) Outside the box: Genomic approach to acute porphyria
-
Thunell S. (Far) Outside the box: genomic approach to acute porphyria. Physiol Res 2006; 55: S43-S66.
-
(2006)
Physiol Res
, vol.55
, pp. 43-66
-
-
Thunell, S.1
-
354
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell 1995; 83: 841-850.
-
(1995)
Cell
, vol.83
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
355
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 2005; 24: 7410-7425.
-
(2005)
Oncogene
, vol.24
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
356
-
-
33646782964
-
FOXO factors: A matter of life and death
-
Huang H, Tindall DJ. FOXO factors: a matter of life and death. Future Oncol 2006; 2: 83-89.
-
(2006)
Future Oncol
, vol.2
, pp. 83-89
-
-
Huang, H.1
Tindall, D.J.2
-
357
-
-
25444496757
-
Chemistry and structural biology of androgen receptor
-
Gao W, Bohl CE, Dalton JT. Chemistry and structural biology of androgen receptor. Chem Rev 2005; 105: 3352-3370.
-
(2005)
Chem Rev
, vol.105
, pp. 3352-3370
-
-
Gao, W.1
Bohl, C.E.2
Dalton, J.T.3
-
358
-
-
0035912833
-
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor
-
Lin HK, Yeh S, Kang HY, Chang C. Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor. Proc Natl Acad Sci USA 2001; 98: 7200-7205.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7200-7205
-
-
Lin, H.K.1
Yeh, S.2
Kang, H.Y.3
Chang, C.4
-
359
-
-
0035827510
-
Antagonism between PTEN/MMAC1/TEP-1 and androgen receptor in growth and apoptosis of prostatic cancer cells
-
Li P, Nicosia SV, Bai W. Antagonism between PTEN/MMAC1/TEP-1 and androgen receptor in growth and apoptosis of prostatic cancer cells. J Biol Chem 2001; 276: 20444-20450.
-
(2001)
J Biol Chem
, vol.276
, pp. 20444-20450
-
-
Li, P.1
Nicosia, S.V.2
Bai, W.3
-
360
-
-
33746930170
-
FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer
-
Dong XY, Chen C, Sun X, et al. FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer. Cancer Res 2006; 66: 6998-7006.
-
(2006)
Cancer Res
, vol.66
, pp. 6998-7006
-
-
Dong, X.Y.1
Chen, C.2
Sun, X.3
-
361
-
-
0030669765
-
Interaction between the amino-and carboxyl-terminal regions of the rat androgen receptor modulates transcriptional activity and is influenced by nuclear receptor coactivators
-
Ikonen T, Palvimo JJ, Janne OA. Interaction between the amino-and carboxyl-terminal regions of the rat androgen receptor modulates transcriptional activity and is influenced by nuclear receptor coactivators. J Biol Chem. 1997; 272: 29821-29828.
-
(1997)
J Biol Chem
, vol.272
, pp. 29821-29828
-
-
Ikonen, T.1
Palvimo, J.J.2
Janne, O.A.3
-
362
-
-
0029560494
-
Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer
-
Langley E, Zhou ZX, Wilson EM. Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer. J Biol Chem 1995; 270: 29983-29990.
-
(1995)
J Biol Chem
, vol.270
, pp. 29983-29990
-
-
Langley, E.1
Zhou, Z.X.2
Wilson, E.M.3
-
363
-
-
58849127943
-
FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment
-
Ma Q, Fu W, Li P, et al. FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment. Mol Endocrinol 2009; 23: 213-225.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 213-225
-
-
Ma, Q.1
Fu, W.2
Li, P.3
-
364
-
-
34147101043
-
Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor
-
Fan W, Yanase T, Morinaga H, et al. Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor. J Biol Chem 2007; 282: 7329-7338.
-
(2007)
J Biol Chem
, vol.282
, pp. 7329-7338
-
-
Fan, W.1
Yanase, T.2
Morinaga, H.3
-
365
-
-
47949126042
-
FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells
-
Cornforth AN, Davis JS, Khanifar E, Nastiuk KL, Krolewski JJ. FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells. Oncogene 2008; 27: 4422-4433.
-
(2008)
Oncogene
, vol.27
, pp. 4422-4433
-
-
Cornforth, A.N.1
Davis, J.S.2
Khanifar, E.3
Nastiuk, K.L.4
Krolewski, J.J.5
-
366
-
-
61749091464
-
Modification of androgen receptor function by IGF-1 signaling implications in the mechanism of refractory prostate carcinoma
-
Yanase T, Fan W. Modification of androgen receptor function by IGF-1 signaling implications in the mechanism of refractory prostate carcinoma. Vitam Horm 2009; 80: 649-666.
-
(2009)
Vitam Horm
, vol.80
, pp. 649-666
-
-
Yanase, T.1
Fan, W.2
-
367
-
-
33644638521
-
Estrogen receptors and human disease
-
Deroo BJ, Korach KS. Estrogen receptors and human disease. J Clin Invest 2006; 116: 561-570.
-
(2006)
J Clin Invest
, vol.116
, pp. 561-570
-
-
Deroo, B.J.1
Korach, K.S.2
-
368
-
-
0031240327
-
Mammary gland development and tumorigenesis in estrogen receptor knockout mice
-
Bocchinfuso WP, Korach KS. Mammary gland development and tumorigenesis in estrogen receptor knockout mice. J Mammary Gland Biol Neoplasia 1997; 2: 323-334.
-
(1997)
J Mammary Gland Biol Neoplasia
, vol.2
, pp. 323-334
-
-
Bocchinfuso, W.P.1
Korach, K.S.2
-
369
-
-
31544451511
-
RNA interference-mediated depletion of phosphoinositide 3-kinase activates forkhead box class O transcription factors and induces cell cycle arrest and apoptosis in breast carcinoma cells
-
Reagan-Shaw S, Ahmad N. RNA interference-mediated depletion of phosphoinositide 3-kinase activates forkhead box class O transcription factors and induces cell cycle arrest and apoptosis in breast carcinoma cells. Cancer Res 2006; 66: 1062-1069.
-
(2006)
Cancer Res
, vol.66
, pp. 1062-1069
-
-
Reagan-Shaw, S.1
Ahmad, N.2
-
370
-
-
10744230034
-
FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines
-
Sunters A, Fernandez de Mattos S, Stahl M, et al. FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J Biol Chem 2003; 278: 49795-49805.
-
(2003)
J Biol Chem
, vol.278
, pp. 49795-49805
-
-
Sunters, A.1
de Mattos, F.S.2
Stahl, M.3
-
371
-
-
0037472647
-
Estrogen regulation of Pak1 and FKHR pathways in breast cancer cells
-
azumdar A, Kumar R. Estrogen regulation of Pak1 and FKHR pathways in breast cancer cells. FEBS Lett 2003; 535: 6-10.
-
(2003)
FEBS Lett
, vol.535
, pp. 6-10
-
-
Azumdar, A.1
Kumar, R.2
-
372
-
-
44849127978
-
Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis
-
Zou Y, Tsai WB, Cheng CJ, et al. Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis. Breast Cancer Res 2008; 10: R21.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Zou, Y.1
Tsai, W.B.2
Cheng, C.J.3
-
373
-
-
22844438667
-
Crosstalk between p53 and FOXO transcription factors
-
You H, Mak TW. Crosstalk between p53 and FOXO transcription factors. Cell Cycle 2005; 4: 37-38.
-
(2005)
Cell Cycle
, vol.4
, pp. 37-38
-
-
You, H.1
Mak, T.W.2
-
374
-
-
70350565471
-
Evan GI. p53--a Jack of all trades but master of none
-
Junttila MR, Evan GI. p53--a Jack of all trades but master of none. Nat Rev Cancer 2009; 9: 821-829.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 821-829
-
-
Junttila, M.R.1
-
375
-
-
33745163907
-
Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a
-
You H, Yamamoto K, Mak TW. Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a. Proc Natl Acad Sci USA 2006; 103: 9051-9056.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9051-9056
-
-
You, H.1
Yamamoto, K.2
Mak, T.W.3
-
376
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
-
Nemoto S, Fergusson MM, Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004; 306: 2105-2108.
-
(2004)
Science
, vol.306
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
377
-
-
0037349289
-
P53 has a direct apoptogenic role at the mitochondria
-
Mihara M, Erster S, Zaika A, et al. P53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003; 11: 577-590.
-
(2003)
Mol Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
-
378
-
-
68049111575
-
P53 negatively regulates the transcriptional activity of FOXO3a under oxidative stress
-
Miyaguchi Y, Tsuchiya K, Sakamoto K. P53 negatively regulates the transcriptional activity of FOXO3a under oxidative stress. Cell Biol Int 2009; 33: 853-860.
-
(2009)
Cell Biol Int
, vol.33
, pp. 853-860
-
-
Miyaguchi, Y.1
Tsuchiya, K.2
Sakamoto, K.3
-
379
-
-
33846214693
-
Regulation of the Arf tumor suppressor in Emicro-Myc transgenic mice: Longitudinal study of Myc-induced lymphomagenesis
-
Bertwistle D, Sherr CJ. Regulation of the Arf tumor suppressor in Emicro-Myc transgenic mice: longitudinal study of Myc-induced lymphomagenesis. Blood 2007; 109: 792-794.
-
(2007)
Blood
, vol.109
, pp. 792-794
-
-
Bertwistle, D.1
Sherr, C.J.2
-
380
-
-
13144253122
-
Reversing drug resistance in vivo
-
Wendel HG, Lowe SW. Reversing drug resistance in vivo. Cell Cycle 2004; 3: 847-849.
-
(2004)
Cell Cycle
, vol.3
, pp. 847-849
-
-
Wendel, H.G.1
Lowe, S.W.2
-
381
-
-
3543028648
-
Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins
-
Bouchard C, Marquardt J, Bras A, Medema RH, Eilers M. Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. Embo J 2004; 23:2830-2840.
-
(2004)
Embo J
, vol.23
, pp. 2830-2840
-
-
Bouchard, C.1
Marquardt, J.2
Bras, A.3
Medema, R.H.4
Eilers, M.5
-
382
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 1983; 304: 596-602.
-
(1983)
Nature
, vol.304
, pp. 596-602
-
-
Land, H.1
Parada, L.F.2
Weinberg, R.A.3
-
383
-
-
35948946514
-
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf
-
Bouchard C, Lee S, Paulus-Hock V, Loddenkemper C, Eilers M, Schmitt CA. FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf. Genes Dev 2007; 21: 2775-2787.
-
(2007)
Genes Dev
, vol.21
, pp. 2775-2787
-
-
Bouchard, C.1
Lee, S.2
Paulus-Hock, V.3
Loddenkemper, C.4
Eilers, M.5
Schmitt, C.A.6
-
384
-
-
2142662252
-
Reciprocal control of Forkhead box O 3a and c-Myc via the phosphatidylinositol 3-kinase pathway coordinately regulates p27Kip1 levels
-
Chandramohan V, Jeay S, Pianetti S, Sonenshein GE. Reciprocal control of Forkhead box O 3a and c-Myc via the phosphatidylinositol 3-kinase pathway coordinately regulates p27Kip1 levels. J Immunol 2004; 172: 5522-5527.
-
(2004)
J Immunol
, vol.172
, pp. 5522-5527
-
-
Chandramohan, V.1
Jeay, S.2
Pianetti, S.3
Sonenshein, G.E.4
-
385
-
-
0035967099
-
Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc
-
Yang W, Shen J, Wu M, et al. Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc. Oncogene 2001; 20: 1688-1702.
-
(2001)
Oncogene
, vol.20
, pp. 1688-1702
-
-
Yang, W.1
Shen, J.2
Wu, M.3
-
386
-
-
49049100243
-
C-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor
-
Chandramohan V, Mineva ND, Burke B, et al. C-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor. J Cell Biochem 2008; 104: 2091-2106.
-
(2008)
J Cell Biochem
, vol.104
, pp. 2091-2106
-
-
Chandramohan, V.1
Mineva, N.D.2
Burke, B.3
-
387
-
-
0028349735
-
Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong Z, Wen Z, Darnell JE, Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994; 264: 95-98.
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell Jr., J.E.3
-
388
-
-
0032525155
-
Multiple routes to astrocytic differentiation in the CNS
-
Rajan P, McKay RD. Multiple routes to astrocytic differentiation in the CNS. J Neurosci 1998; 18: 3620-3629.
-
(1998)
J Neurosci
, vol.18
, pp. 3620-3629
-
-
Rajan, P.1
McKay, R.D.2
-
389
-
-
33746397211
-
Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex
-
Yoshimatsu T, Kawaguchi D, Oishi K, et al. Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development 2006; 133: 2553-2563.
-
(2006)
Development
, vol.133
, pp. 2553-2563
-
-
Yoshimatsu, T.1
Kawaguchi, D.2
Oishi, K.3
-
390
-
-
39449093328
-
Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway
-
de la Iglesia N, Konopka G, Puram SV, et al. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev 2008; 22: 449-462.
-
(2008)
Genes Dev
, vol.22
, pp. 449-462
-
-
de la Iglesia, N.1
Konopka, G.2
Puram, S.V.3
-
391
-
-
2442657786
-
IL-6 is required for glioma development in a mouse model
-
Weissenberger J, Loeffler S, Kappeler A, et al. IL-6 is required for glioma development in a mouse model. Oncogene 2004; 23: 3308-3316.
-
(2004)
Oncogene
, vol.23
, pp. 3308-3316
-
-
Weissenberger, J.1
Loeffler, S.2
Kappeler, A.3
-
392
-
-
25444454543
-
New and old functions of STAT3: A pivotal target for individualized treatment of cancer
-
Inghirami G, Chiarle R, Simmons WJ, Piva R, Schlessinger K, Levy DE. New and old functions of STAT3: a pivotal target for individualized treatment of cancer. Cell Cycle 2005; 4: 1131-1133.
-
(2005)
Cell Cycle
, vol.4
, pp. 1131-1133
-
-
Inghirami, G.1
Chiarle, R.2
Simmons, W.J.3
Piva, R.4
Schlessinger, K.5
Levy, D.E.6
-
393
-
-
3042748279
-
Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
-
Konnikova L, Kotecki M, Kruger MM, Cochran BH. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer 2003; 3: 23.
-
(2003)
BMC Cancer
, vol.3
, pp. 23
-
-
Konnikova, L.1
Kotecki, M.2
Kruger, M.M.3
Cochran, B.H.4
-
394
-
-
61449095573
-
Leptin at 14 y of age: An ongoing story
-
Friedman JM. Leptin at 14 y of age: an ongoing story. Am J Clin Nutr 2009; 89: 973S-979S.
-
(2009)
Am J Clin Nutr
, vol.89
-
-
Friedman, J.M.1
-
395
-
-
17844401704
-
Anatomy and regulation of the central melanocortin system
-
Cone RD. Anatomy and regulation of the central melanocortin system. Nat Neurosci 2005; 8: 571-578.
-
(2005)
Nat Neurosci
, vol.8
, pp. 571-578
-
-
Cone, R.D.1
-
396
-
-
0037456304
-
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
-
Bates SH, Stearns WH, Dundon TA, et al. STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature 2003; 421: 856-859.
-
(2003)
Nature
, vol.421
, pp. 856-859
-
-
Bates, S.H.1
Stearns, W.H.2
Dundon, T.A.3
-
397
-
-
11144357516
-
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo
-
Inoue H, Ogawa W, Ozaki M, et al. Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nat Med 2004; 10: 168-174.
-
(2004)
Nat Med
, vol.10
, pp. 168-174
-
-
Inoue, H.1
Ogawa, W.2
Ozaki, M.3
-
398
-
-
64049109876
-
STAT3 inhibition of gluconeogenesis is downregulated by SirT1
-
Nie Y, Erion DM, Yuan Z, et al. STAT3 inhibition of gluconeogenesis is downregulated by SirT1. Nat Cell Biol 2009; 11: 492-500.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 492-500
-
-
Nie, Y.1
Erion, D.M.2
Yuan, Z.3
-
399
-
-
0037310863
-
RUNX transcription factors as key targets of TGF-beta superfamily signaling
-
Ito Y, Miyazono K. RUNX transcription factors as key targets of TGF-beta superfamily signaling. Curr Opin Genet Dev 2003; 13: 43-47.
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 43-47
-
-
Ito, Y.1
Miyazono, K.2
-
400
-
-
18344389720
-
Causal relationship between the loss of RUNX3 expression and gastric cancer
-
Li QL, Ito K, Sakakura C, et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 2002; 109: 113-124.
-
(2002)
Cell
, vol.109
, pp. 113-124
-
-
Li, Q.L.1
Ito, K.2
Sakakura, C.3
-
401
-
-
33646189483
-
RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells
-
Yamamura Y, Lee WL, Inoue K, Ida H, Ito Y. RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells. J Biol Chem 2006; 281: 5267-5276.
-
(2006)
J Biol Chem
, vol.281
, pp. 5267-5276
-
-
Yamamura, Y.1
Lee, W.L.2
Inoue, K.3
Ida, H.4
Ito, Y.5
-
402
-
-
0038043227
-
Smad3 potentiates transforming growth factor beta (TGFbeta)-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes
-
Wildey GM, Patil S, Howe PH. Smad3 potentiates transforming growth factor beta (TGFbeta)-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes. J Biol Chem 2003; 278: 18069-18077.
-
(2003)
J Biol Chem
, vol.278
, pp. 18069-18077
-
-
Wildey, G.M.1
Patil, S.2
Howe, P.H.3
-
403
-
-
67749127709
-
Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells
-
Wildey GM, Howe PH. Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells. J Biol Chem 2009; 284: 20227-20239.
-
(2009)
J Biol Chem
, vol.284
, pp. 20227-20239
-
-
Wildey, G.M.1
Howe, P.H.2
-
404
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 2002; 296: 1634-1635.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
405
-
-
0032969285
-
Tumor necrosis factor receptor and Fas signaling mechanisms
-
Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu Rev Immunol 1999; 17: 331-367.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 331-367
-
-
Wallach, D.1
Varfolomeev, E.E.2
Malinin, N.L.3
Goltsev, Y.V.4
Kovalenko, A.V.5
Boldin, M.P.6
-
406
-
-
17144384376
-
NF-kappaB and JNK: An intricate affair
-
Bubici C, Papa S, Pham CG, Zazzeroni F, Franzoso G. NF-kappaB and JNK: an intricate affair. Cell Cycle 2004; 3: 1524-1529.
-
(2004)
Cell Cycle
, vol.3
, pp. 1524-1529
-
-
Bubici, C.1
Papa, S.2
Pham, C.G.3
Zazzeroni, F.4
Franzoso, G.5
-
407
-
-
37549050887
-
FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-kappaB
-
Lee HY, Youn SW, Kim JY, et al. FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-kappaB. Arterioscler Thromb Vasc Biol 2008; 28: 112-120.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 112-120
-
-
Lee, H.Y.1
Youn, S.W.2
Kim, J.Y.3
-
408
-
-
70349507649
-
FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation
-
Zhou W, Cao Q, Peng Y, et al. FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation. Gastroenterology 2009; 137:1403-1414.
-
(2009)
Gastroenterology
, vol.137
, pp. 1403-1414
-
-
Zhou, W.1
Cao, Q.2
Peng, Y.3
-
409
-
-
0031005095
-
Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma
-
Genini M, Schwalbe P, Scholl FA, Remppis A, Mattei MG, Schafer BW. Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma. DNA Cell Biol 1997; 16: 433-442.
-
(1997)
DNA Cell Biol
, vol.16
, pp. 433-442
-
-
Genini, M.1
Schwalbe, P.2
Scholl, F.A.3
Remppis, A.4
Mattei, M.G.5
Schafer, B.W.6
-
410
-
-
1642458404
-
Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes
-
Purcell NH, Darwis D, Bueno OF, Muller JM, Schule R, Molkentin JD. Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes. Mol Cell Biol 2004; 24: 1081-1095.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1081-1095
-
-
Purcell, N.H.1
Darwis, D.2
Bueno, O.F.3
Muller, J.M.4
Schule, R.5
Molkentin, J.D.6
-
411
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
-
Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. Embo J 2001; 20: 5197-5206.
-
(2001)
Embo J
, vol.20
, pp. 5197-5206
-
-
Masson, N.1
Willam, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
412
-
-
0035917808
-
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001; 292: 468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
-
413
-
-
0035917313
-
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
-
Ivan M, Kondo K, Yang H, et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001; 292: 464-468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
-
414
-
-
40649089427
-
PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a)
-
Emerling BM, Weinberg F, Liu JL, Mak TW, Chandel NS. PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a). Proc Natl Acad Sci USA 2008; 105: 2622-2627.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2622-2627
-
-
Emerling, B.M.1
Weinberg, F.2
Liu, J.L.3
Mak, T.W.4
Chandel, N.S.5
-
415
-
-
0037326985
-
PI3K-signalling in B- and T-cells: Insights from gene-targeted mice
-
Okkenhaug K, Vanhaesebroeck B. PI3K-signalling in B- and T-cells: insights from gene-targeted mice. Biochem Soc Trans 2003; 31: 270-274.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 270-274
-
-
Okkenhaug, K.1
Vanhaesebroeck, B.2
-
416
-
-
1342292522
-
Phosphoinositide 3-kinase: Diverse roles in immune cell activation
-
Deane JA, Fruman DA. Phosphoinositide 3-kinase: diverse roles in immune cell activation. Annu Rev Immunol 2004; 22: 563-598.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 563-598
-
-
Deane, J.A.1
Fruman, D.A.2
-
417
-
-
2342622123
-
Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors
-
Yusuf I, Zhu X, Kharas MG, Chen J, Fruman DA. Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors. Blood 2004; 104: 784-787.
-
(2004)
Blood
, vol.104
, pp. 784-787
-
-
Yusuf, I.1
Zhu, X.2
Kharas, M.G.3
Chen, J.4
Fruman, D.A.5
-
418
-
-
0037094096
-
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
-
Stahl M, Dijkers PF, Kops GJ, et al. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 2002; 168: 5024-5031.
-
(2002)
J Immunol
, vol.168
, pp. 5024-5031
-
-
Stahl, M.1
Dijkers, P.F.2
Kops, G.J.3
-
419
-
-
33644538251
-
FOXO transcription factors cooperate with delta EF1 to activate growth suppressive genes in B lymphocytes
-
Chen J, Yusuf I, Andersen HM, Fruman DA. FOXO transcription factors cooperate with delta EF1 to activate growth suppressive genes in B lymphocytes. J Immunol 2006; 176: 2711-2721.
-
(2006)
J Immunol
, vol.176
, pp. 2711-2721
-
-
Chen, J.1
Yusuf, I.2
Andersen, H.M.3
Fruman, D.A.4
-
420
-
-
2342628539
-
Phosphoinositide 3-kinase and Forkhead, a switch for cell division
-
Martinez-Gac L, Alvarez B, Garcia Z, Marques M, Arrizabalaga M, Carrera AC. Phosphoinositide 3-kinase and Forkhead, a switch for cell division. Biochem Soc Trans 2004; 32: 360-361.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 360-361
-
-
Martinez-Gac, L.1
Alvarez, B.2
Garcia, Z.3
Marques, M.4
Arrizabalaga, M.5
Carrera, A.C.6
-
421
-
-
0036120725
-
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors
-
Kops GJ, Medema RH, Glassford J, et al. Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. Mol Cell Biol 2002; 22: 2025-2036.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2025-2036
-
-
Kops, G.J.1
Medema, R.H.2
Glassford, J.3
-
422
-
-
0035193044
-
The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation
-
Fontemaggi G, Gurtner A, Strano S, et al. The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation. Mol Cell Biol 2001; 21: 8461-8470.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8461-8470
-
-
Fontemaggi, G.1
Gurtner, A.2
Strano, S.3
-
423
-
-
0038324070
-
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins
-
Postigo AA, Depp JL, Taylor JJ, Kroll KL. Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. Embo J 2003; 22: 2453-2462.
-
(2003)
Embo J
, vol.22
, pp. 2453-2462
-
-
Postigo, A.A.1
Depp, J.L.2
Taylor, J.J.3
Kroll, K.L.4
-
424
-
-
0032080450
-
Transcriptional repression of the IL-2 gene in Th cells by ZEB
-
Yasui DH, Genetta T, Kadesch T, et al. Transcriptional repression of the IL-2 gene in Th cells by ZEB. J Immunol 1998; 160: 4433-4440.
-
(1998)
J Immunol
, vol.160
, pp. 4433-4440
-
-
Yasui, D.H.1
Genetta, T.2
Kadesch, T.3
-
425
-
-
0030906128
-
Impairment of T cell development in deltaEF1 mutant mice
-
Higashi Y, Moribe H, Takagi T, et al. Impairment of T cell development in deltaEF1 mutant mice. J Exp Med 1997; 185: 1467-1479.
-
(1997)
J Exp Med
, vol.185
, pp. 1467-1479
-
-
Higashi, Y.1
Moribe, H.2
Takagi, T.3
-
426
-
-
0034716888
-
A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila
-
Grosshans J, Wieschaus E. A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila. Cell 2000; 101: 523-531.
-
(2000)
Cell
, vol.101
, pp. 523-531
-
-
Grosshans, J.1
Wieschaus, E.2
-
427
-
-
77952672913
-
Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells
-
Zanella F, Renner O, Garcia B, et al. Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells. Oncogene 2010; 29: 2973-2982.
-
(2010)
Oncogene
, vol.29
, pp. 2973-2982
-
-
Zanella, F.1
Renner, O.2
Garcia, B.3
-
428
-
-
0034463096
-
Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-lnduced kinase (Sgk): Evidence for A kinase-independent signaling by FSH in granulosa cells
-
Gonzalez-Robayna IJ, Falender AE, Ochsner S, Firestone GL, Richards JS. Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-lnduced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells. Mol Endocrinol 2000; 14: 1283-1300.
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1283-1300
-
-
Gonzalez-Robayna, I.J.1
Falender, A.E.2
Ochsner, S.3
Firestone, G.L.4
Richards, J.S.5
-
429
-
-
2942601056
-
Human follicle-stimulating hormone (FSH) receptor interacts with the adaptor protein APPL1 in HEK 293 cells: Potential involvement of the PI3K pathway in FSH signaling
-
Nechamen CA, Thomas RM, Cohen BD, et al. Human follicle-stimulating hormone (FSH) receptor interacts with the adaptor protein APPL1 in HEK 293 cells: potential involvement of the PI3K pathway in FSH signaling. Biol Reprod 2004; 71:629-636.
-
(2004)
Biol Reprod
, vol.71
, pp. 629-636
-
-
Nechamen, C.A.1
Thomas, R.M.2
Cohen, B.D.3
-
430
-
-
33751239461
-
APPL1, APPL2, Akt2 and FOXO1a interact with FSHR in a potential signaling complex
-
Nechamen CA, Thomas RM, Dias JA. APPL1, APPL2, Akt2 and FOXO1a interact with FSHR in a potential signaling complex. Mol Cell Endocrinol 2007; 260-262: 93-99.
-
(2007)
Mol Cell Endocrinol
, vol.260-262
, pp. 93-99
-
-
Nechamen, C.A.1
Thomas, R.M.2
Dias, J.A.3
-
431
-
-
2442485795
-
Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation
-
Alam H, Maizels ET, Park Y, et al. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation. J Biol Chem 2004; 279: 19431-19440.
-
(2004)
J Biol Chem
, vol.279
, pp. 19431-19440
-
-
Alam, H.1
Maizels, E.T.2
Park, Y.3
-
432
-
-
18344387559
-
Phosphorylation-specific prolyl isomerization: Is there an underlying theme?
-
Wulf G, Finn G, Suizu F, Lu KP. Phosphorylation-specific prolyl isomerization: is there an underlying theme? Nat Cell Biol 2005; 7: 435-441.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 435-441
-
-
Wulf, G.1
Finn, G.2
Suizu, F.3
Lu, K.P.4
-
433
-
-
0037351048
-
Prolyl isomerase Pin1: A catalyst for oncogenesis and a potential therapeutic target in cancer
-
Ryo A, Liou YC, Lu KP, Wulf G. Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. J Cell Sci 2003; 116: 773-783.
-
(2003)
J Cell Sci
, vol.116
, pp. 773-783
-
-
Ryo, A.1
Liou, Y.C.2
Lu, K.P.3
Wulf, G.4
-
434
-
-
54749134224
-
The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors
-
Brenkman AB, de Keizer PL, van den Broek NJ, et al. The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors. Cancer Res 2008; 68: 7597-605.
-
(2008)
Cancer Res
, vol.68
, pp. 7597-7605
-
-
Brenkman, A.B.1
de Keizer, P.L.2
van den Broek, N.J.3
-
436
-
-
0028922462
-
Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease
-
Wang ZQ, Auer B, Stingl L, et al. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev 1995; 9: 509-520.
-
(1995)
Genes Dev
, vol.9
, pp. 509-520
-
-
Wang, Z.Q.1
Auer, B.2
Stingl, L.3
-
437
-
-
34548183836
-
PolyADP-ribosylation and cancer
-
Miwa M, Masutani M. PolyADP-ribosylation and cancer. Cancer Sci 2007; 98: 1528-1535.
-
(2007)
Cancer Sci
, vol.98
, pp. 1528-1535
-
-
Miwa, M.1
Masutani, M.2
-
438
-
-
10944253639
-
Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway
-
Ju BG, Solum D, Song EJ, et al. Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway. Cell 2004; 119: 815-829.
-
(2004)
Cell
, vol.119
, pp. 815-829
-
-
Ju, B.G.1
Solum, D.2
Song, E.J.3
-
439
-
-
44649130038
-
Transcriptional control by PARP-1: Chromatin modulation, enhancer-binding, coregulation, and insulation
-
Kraus WL. Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation. Curr Opin Cell Biol 2008; 20: 294-302.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 294-302
-
-
Kraus, W.L.1
-
440
-
-
64049087377
-
Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1
-
Sakamaki J, Daitoku H, Yoshimochi K, Miwa M, Fukamizu A. Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1. Biochem Biophys Res Commun 2009; 382: 497-502.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 497-502
-
-
Sakamaki, J.1
Daitoku, H.2
Yoshimochi, K.3
Miwa, M.4
Fukamizu, A.5
|