Transport of Corilagin, Gallic Acid, and Ellagic Acid from Fructus Phyllanthi Tannin Fraction in Caco-2 Cell Monolayers

Evidence-based Complementary and Alternative Medicine

Volumn 2016, Issue , 2016, Pages

  Mao, Xin ^a,b   Wu, Ling Fang ^a   Zhao, Hai Juan ^a   Liang, Wen Yi ^a   Chen, Wen Jing ^a   Han, Shu Xian ^b   Qi, Qi ^a   Cui, Ya Ping ^a   Li, Shi ^a   Yang, Guang Hui ^a   Shao, Yan Yan ^a   Zhu, Dan ^a   Wang, Ru Feng ^a   You, Yun ^a,b   Zhang, Lan Zhen ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CORILAGIN; ELLAGIC ACID; EMBLICA OFFICINALIS EXTRACT; GALLIC ACID; INDOMETACIN; PHLORIZIN; TANNIN DERIVATIVE; TIGHT JUNCTION PROTEIN; VERAPAMIL;

ARTICLE; CACO 2 CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ELIMINATION; DRUG MECHANISM; DRUG PENETRATION; DRUG TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYLLANTHUS; RAT;

EID: 84990855347     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2016/9205379     Document Type: Article

References (42)

1. T. Yoshida, Y. Amakura, andM. Yoshimura, "Structural features and biological properties of ellagitannins in some plant families of the order myrtales, " International Journal of Molecular Sciences, vol. 11, no. 1, pp. 79-106, 2010.
2. L. Jia, H. Jin, M. Lv et al., "Abstract 5550: corilagin, an antitumor herb medicine, sensitizes paclitaxel and carboplatin by primarily inhibiting glycolysis pathways in epithelial ovarian cancer, " Cancer Research, vol. 75, no. 15, supplement, pp. 5550-5550, 2015.
3. L. Jia, H. Jin, J. Zhou et al., "A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-signaling pathways, " BMC Complementary and Alternative Medicine, vol. 13, article 33, 2013.
4. Y.-J. Guo, T. Luo, F. Wu et al., "Corilagin protects against HSV1 encephalitis through inhibiting the TLR2 signaling pathways in vivo and in vitro, " Molecular Neurobiology, vol. 52, no. 3, pp. 1547-1560, 2014.
5. J. Moreira, L. C. Klein-Júnior, V. C. Filho, and F. D. C. Buzzi, "Anti-hyperalgesic activity of corilagin, a tannin isolated from Phyllanthus niruri L. (Euphorbiaceae), " Journal of Ethnopharmacology, vol. 146, no. 1, pp. 318-323, 2013.
6. M. Shimizu, S. Shiota, T. Mizushima et al., "Marked potentiation of activity of-lactams against methicillin-resistant Staphylococcus aureus by corilagin, " Antimicrobial Agents & Chemotherapy, vol. 45, no. 11, pp. 3198-3201, 2001.
7. B. Badhani, N. Sharma, and R. Kakkar, "Gallic acid: A versatile antioxidant with promising therapeutic and industrial applications, " RSC Advances, vol. 5, no. 35, pp. 27540-27557, 2015.
8. A. S. Meyer, M. Heinonen, andE. N. Frankel, "Antioxidant interactions of catechin, cyanidin, caffeic acid, quercetin, and ellagic acid on human LDL oxidation, " Food Chemistry, vol. 61, no. 1-2, pp. 71-75, 1998.
9. W. H. Park and S. H. Kim, "MAPK inhibitors augment gallic acid-induced A549 lung cancer cell death through the enhancement of glutathione depletion, " Oncology Reports, vol. 30, no. 1, pp. 513-519, 2013.
10. R. Vicinanza, Y. Zhang, S. M. Henning, and D. Heber, "Pomegranate juice metabolites, ellagic acid and urolithin A, synergistically inhibit androgen-independent prostate cancer cell growth via distinct effects on cell cycle control and apoptosis, " Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 247504, 12 pages, 2013.
11. Q. Xia, P. Xiao, L. Wang, and J. Kong, "Ethnopharmacology of Phyllanthus emblica L., " Zhongguo Zhong Yao Za Zhi, vol. 22, no. 9, pp. 515-525, 1998 (Chinese).
12. L.-Z. Zhang, W.-H. Zhao, Y.-J. Guo, G.-Z. Tu, S. Lin, and L.-G. Xin, "Studies on chemical constituents in fruits of tibetan medicine Phyllanthus emblica, " Zhongguo Zhongyao Zazhi, vol. 28, no. 10, pp. 942-943, 2003.
13. H.-J. Zhao, T. Liu, X. Mao et al., "Fructus Phyllanthi tannin fraction induces apoptosis and inhibits migration and invasion of human lung squamous carcinoma cells in vitro via MAPK/MMP pathways, " Acta Pharmacologica Sinica, vol. 36, no. 6, pp. 758-768, 2015.
14. L. F. Wu, Pharmacokinetic Study of Fructus Phyllanthi tannin Fraction, Beijing University of Chinese Medicine, Beijing, China, 2014 (Chinese).
15. M. Pinto, S. Robine-Leon, and M. D. Appay, "Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture, " Biology of the Cell, vol. 47, no. 3, pp. 323-330, 1983.
16. A. R. Hilgers, R. A. Conradi, and P. S. Burton, "Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa, " Pharmaceutical Research, vol. 7, no. 9, pp. 902-910, 1990.
17. H. Gutmann, G. Fricker, M. Török, S. Michael, C. Beglinger, and J. Drewe, "Evidence for different ABC transporters in Caco-2 cellsmodulating drug uptake, " Pharmaceutical Research, vol. 16, no. 3, pp. 402-407, 1999.
18. T. Hirohashi, H. Suzuki, X.-Y. Chu, I. Tamai, A. Tsuji, and Y. Sugiyama, "Function and expression of multidrug resistanceassociated protein family in human colon adenocarcinoma cells (Caco-2), " Journal of Pharmacology and Experimental Therapeutics, vol. 292, no. 1, pp. 265-270, 2000.
19. G. Englund, F. Rorsman, A. Rönnblom et al., "Regional levels of drug transporters along the human intestinal tract: coexpression of ABC and SLC transporters and comparison with Caco-2 cells, " European Journal of Pharmaceutical Sciences, vol. 29, no. 3-4, supplement, pp. 269-277, 2006.
20. J. I. Fletcher, M. Haber, M. J. Henderson, and M. D. Norris, "ABC transporters in cancer:more than just drug efflux pumps, " Nature Reviews Cancer, vol. 10, no. 2, pp. 147-156, 2010.
21. Z. Teng, C. Yuan, F. Zhang et al., "Intestinal absorption and first-passmetabolismof polyphenol compounds in rat and their transport dynamics in caco-2 cells, " PLoS ONE, vol. 7, no. 1, Article ID e29647, 2012.
22. L. Liu, L. Guo, C. Zhao, X. Wu, R. Wang, and C. Liu, "Characterization of the intestinal absorption of seven flavonoids from the flowers of Trollius chinensis using the Caco-2 cell monolayer model, " PLoS ONE, vol. 10, no. 3, Article IDe0119263, 2015.
23. J. B. Vaidyanathan and T. Walle, "Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2, " Journal of Pharmacology & Experimental Therapeutics, vol. 307, no. 2, pp. 745-752, 2003.
24. M. P. Draper, R. L. Martell, and S. B. Levy, "Indomethacinmediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not Pglycoprotein, " British Journal of Cancer, vol. 75, no. 6, pp. 810-815, 1997.
25. H. M. Prime-Chapman, R. A. Fearn, A. E. Cooper, V. Moore, and B. H. Hirst, "Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells, " Journal of Pharmacology & Experimental Therapeutics, vol. 311, no. 2, pp. 476-484, 2004.
26. W. Zhou, L.-Q. Di, J. Wang et al., "Intestinal absorption of forsythoside A in in situ single-pass intestinal perfusion and in vitro Caco-2 cell models, " Acta Pharmacologica Sinica, vol. 33, no. 8, pp. 1069-1079, 2012.
27. G. Burckhardt and B. C. Burckhardt, "In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy, " in Drug Transporters, pp. 29-104, Springer, Heidelberg, Germany, 2011.
28. Y. Chen, X. Liu, R. Pan et al., "Intestinal transport of 3, 6-disinapoylsucrose, a major active component of Polygala tenuifolia, using Caco-2 cell monolayer and in situ rat intestinal perfusionmodels, " PlantaMedica, vol. 79, no. 15, pp. 1434-1439, 2013.
29. E. K. Anderberg and P. Artursson, "Epithelial transport of drugs in cell culture. VIII: effects of sodium dodecyl sulfate on cell membrane and tight junction permeability in human intestinal epithelial (Caco-2) cells, " Journal of Pharmaceutical Sciences, vol. 82, no. 4, pp. 392-398, 1993.
30. G. Ranaldi, I. Marigliano, I. Vespignani, G. Perozzi, and Y. Sambuy, "The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line, " Journal of Nutritional Biochemistry, vol. 13, no. 3, pp. 157-167, 2002.
31. X.-F. Sun, H.-Y. Zhang, Q. Xia et al., "HPLC-fingerprint-based quality evaluation on a Tibetan medicine Phyllanthus emblica and its tannin parts, " Zhongguo Zhongyao Zazhi, vol. 39, no. 7, pp. 1173-1178, 2014.
32. Y. Konishi, K. Hagiwara, and M. Shimizu, "Transepithelial transport of fluorescein in Caco-2 cell monolayers and use of such transport in in vitro evaluation of phenolic acid availability, " Bioscience, Biotechnology & Biochemistry, vol. 66, no. 11, pp. 2449-2457, 2002.
33. G. Sandri, M. C. Bonferoni, S. Rossi et al., "Nanoparticles based on N-trimethylchitosan: evaluation of absorption properties using in vitro (Caco-2 cells) and ex vivo (excised rat jejunum) models, " European Journal of Pharmaceutics and Biopharmaceutics, vol. 65, no. 1, pp. 68-77, 2007.
34. J. Boyer, D. Brown, and R. H. Liu, "Uptake of quercetin and quercetin 3-glucoside fromwhole onion and apple peel extracts by Caco-2 cell monolayers, " Journal of Agricultural & Food Chemistry, vol. 52, no. 23, pp. 7172-7179, 2004.
35. X.-L. Liang, L.-J. Zhao, Z.-G. Liao et al., "Transport properties of puerarin and effect of Radix Angelicae Dahuricae extract on the transport of puerarin in Caco-2 cell model, " Journal of Ethnopharmacology, vol. 144, no. 3, pp. 677-682, 2012.
36. K. Y.-Z. Zheng, R. C.-Y. Choi, A. J.-Y. Guo et al., "Themembrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: A synergistic action of an ancient herbal decoction Danggui Buxue Tang, " Journal of Pharmaceutical and Biomedical Analysis, vol. 70, pp. 671-679, 2012.
37. L. Yan, P. Yin, C. Ma, and Y. Liu, "Method development and validation for pharmacokinetic and tissue distributions of ellagic acid using ultrahigh performance liquid chromatographytandem mass spectrometry (UPLC-MS/MS), "Molecules, vol. 19, no. 11, pp. 18923-18935, 2014.
38. Y. Konishi, S. Kobayashi, and M. Shimizu, "Transepithelial transport of p-coumaric acid and gallic acid in Caco-2 cell monolayers, " Bioscience, Biotechnology and Biochemistry, vol. 67, no. 11, pp. 2317-2324, 2003.
39. K. Gao, J. Sun, and Z. G. He, "Important application of Caco-2 cell monolayers in the study of the intestinal oral absorption, " Journal of Shenyang Pharmaceutical University, vol. 22, no. 6, pp. 469-474, 2005 (Chinese).
40. N. Li, R. Tsao, Z. Sui, J. Ma, Z. Liu, and Z. Liu, "Intestinal transport of pure diester-type alkaloids from an aconite extract across the Caco-2 cell monolayermodel, " PlantaMedica, vol. 78, no. 7, pp. 692-697, 2012.
41. V. L. M. Madgula, B. Avula, Y. W. Choi et al., "Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers-an in-vitro model of intestinal transport, " Journal of Pharmacy & Pharmacology, vol. 60, no. 3, pp. 363-370, 2008.
42. T. Lindmark, Y. Kimura, and P. Artursson, "Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells, " Journal of Pharmacology and Experimental Therapeutics, vol. 284, no. 1, pp. 362-369, 1998.