Corilagin Protects Against HSV1 Encephalitis Through Inhibiting the TLR2 Signaling Pathways In Vivo and In Vitro

Molecular Neurobiology

Volumn 52, Issue 3, 2015, Pages 1547-1560

  Guo, Yuan Jin ^a   Luo, Tao ^a   Wu, Fei ^b   Liu, Huan ^a   Li, Hua Rong ^a   Mei, Yuan Wu ^a   Zhang, Shu Ling ^a   Tao, Jun Yan ^c   Dong, Ji Hua ^a   Fang, Yuan ^a   Zhao, Lei ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

^c HUBEI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Corilagin; Herpes simplex virus 1; Inflammation; Signaling pathways; Toll like receptor 2

Indexed keywords

CORILAGIN; INTERLEUKIN 6; LENTIVIRUS VECTOR; MACROPHAGE ACTIVATING LIPOPEPTIDE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; ANTIVIRUS AGENT; GLUCOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN-6, MOUSE; LIPOPEPTIDE; MACROPHAGE STIMULATORY LIPOPEPTIDE 2; MEMBRANE PROTEIN; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION FACTOR 88; NEMO PROTEIN, MOUSE; NERVE PROTEIN; SIGNAL PEPTIDE; TANNIN; TIRAP PROTEIN, MOUSE; TLR2 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BV2 CELL LINE; CELL LINE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE SILENCING; GENETIC TRANSFECTION; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS 1; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MOUSE MODEL; MTT ASSAY; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BIOSYNTHESIS; BRAIN; CELL CULTURE; DOWN REGULATION; DRUG EFFECTS; ENCEPHALITIS, HERPES SIMPLEX; GENETICS; METABOLISM; MICROGLIA; PATHOLOGY; PHOSPHORYLATION; PROTEIN PROCESSING; RNA INTERFERENCE;

ANIMALS; ANTIVIRAL AGENTS; BRAIN; CELLS, CULTURED; DOWN-REGULATION; ENCEPHALITIS, HERPES SIMPLEX; GLUCOSIDES; HERPESVIRUS 1, HUMAN; HYDROLYZABLE TANNINS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPEPTIDES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICROGLIA; MYELOID DIFFERENTIATION FACTOR 88; NERVE TISSUE PROTEINS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, INTERLEUKIN-1; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84942821086     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-8947-7     Document Type: Article

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