Nanoparticles based on N-trimethylchitosan: Evaluation of absorption properties using in vitro (Caco-2 cells) and ex vivo (excised rat jejunum) models

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 65, Issue 1, 2007, Pages 68-77

  Sandri, Giuseppina ^a   Bonferoni, Maria Cristina ^a   Rossi, Silvia ^a   Ferrari, Franca ^a   Gibin, Sara ^a   Zambito, Ylenia ^b   Di Colo, Giacomo ^b   Caramella, Carla ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

Absorption properties; CLSM; Ex vivo rat jejunum model; In vitro Caco 2 cell model; Trimethylchitosan nanoparticles

Indexed keywords

CHITOSAN DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; LUCIFER YELLOW; N TRIMETHYLCHITOSAN;

ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; ELECTRIC RESISTANCE; EVALUATION; EX VIVO STUDY; HUMAN; HUMAN CELL; INTERNALIZATION; INTESTINE EPITHELIUM; INTESTINE MUCOSA; MACROMOLECULE; MEMBRANE CURRENT; NANOPARTICLE; NONHUMAN; RAT; SMALL INTESTINE ABSORPTION;

ADHESIVENESS; ANIMALS; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DEXTRANS; DRUG CARRIERS; ELECTRIC IMPEDANCE; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; ISOQUINOLINES; JEJUNUM; MICROSCOPY, CONFOCAL; MUCINS; NANOPARTICLES; PARTICLE SIZE; RATS; TIME FACTORS;

EID: 34547402940     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.07.016     Document Type: Article

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