Transport properties of puerarin and effect of Radix Angelicae Dahuricae extract on the transport of puerarin in Caco-2 cell model

Journal of Ethnopharmacology

Volumn 144, Issue 3, 2012, Pages 677-682

  Liang, Xin Li ^a,b   Zhao, Li Jun ^a   Liao, Zheng Gen ^a   Zhao, Guo Wei ^a   Zhang, Jing ^a   Chao, Yun Chao ^a   Yang, Ming ^a   Yin, Rong Li ^b  

^a JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Absorption; Caco 2 cell monolayer; Puerarin; Radix Angelicae Dahuricae; Transport

Indexed keywords

ANGELICA ROOT EXTRACT; CYCLOSPORIN A; EDETATE SODIUM; PUERARIN; VERAPAMIL; VERLUKAST;

ARTICLE; CELL MEMBRANE; CELL STRAIN CACO 2; DIFFUSION; DRUG ABSORPTION; DRUG MECHANISM; DRUG TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; PH;

ANGELICA; BIOLOGICAL TRANSPORT; CACO-2 CELLS; DRUGS, CHINESE HERBAL; HUMANS; INTESTINAL ABSORPTION; ISOFLAVONES;

PUERARIA;

EID: 84870301233     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.10.011     Document Type: Article

References (27)

1. E. Benlhabib, J.I. Baker, D.E. Keyler, and A.K. Singh Effects of purified puerarin on voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol Journal of Medicinal Food 7 2004 180 186
2. M.G. Busby, A.R. Jeffcoat, L.T. Bloedon, M.A. Koch, T. Black, K.J. Dix, W.D. Heizer, B.F. Thomas, J.M. Hill, J.A. Crowell, and S.H. Zeisel Clinical characteristics and pharmacokinetics of purified soy isoflavones:single-dose administrationto healthy men American Journal of Clinical Nutrition 75 2002 126 136
3. L.M.S. Chan, S. Lowes, and B.H. Hirst The ABCs of drug transport in intestine and liver:efflux proteins limiting drug absorption and bioavailability European Journal of Pharmaceutical Sciences 21 2004 25 51
4. W. Cherdshewasart, and W. Sutjit Correlation of antioxidant activity of major isoflavonoid contents of the phytoestrogen-rich Pueraria mirifica and Pueraria lobata tubers Phytomedicine 15 2007 38 43
5. F.S. Chueh, C.P. Chang, C.C. Chio, and M.T. Lin Puerarin acts through brain serotonergic mechanisms to induce thermal effects Journal of Pharmacological Sciences 96 2004 420 427
6. M.C. Guerra, E. Speroni, M. Broccoli, M. Cangini, P. Pasini, and A. Minghett Comparison between Chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin: Antioxidant properties and effects on rat liver CYP-catalysed drug metabolism Life Sciences 67 2000 2997 3006
7. R. Hayeshi, C. Hilgendorf, P. Artursson, and P. Augustijns Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories European Journal of Pharmaceutical Sciences 35 2008 383 396
8. A.R. Hilgers, R.A. Conradi, and P.S. Burton Caco-2 cell monolayers as a model ford drug transport across the intestinal mucosa Pharmaceutical Research 7 1990 902 910
9. W.M. Keung, and B.L. Vallee Kudzu root: an ancient Chinese source of modern antidipsotropic agents Phytochemistry 47 1998 499 506
10. X.L. Liang, J.Y. Zhu, Z.G. Liao, L.J. Zhao, G.W. Zhao, M. Yang, and Y.C. Chao Intesinal absorption effect of Angelica dahurica extract on puerarin of Puerariae lobatae Radix China Journal of Chinese Materia Medica 37 2012 1477 1482
11. R.C. Lin, S. Guthrie, C.Y. Xie, K. Mai, D.Y. Lee, L. Lumeng, and T.K. Li Isoflavonoid compounds extracted from Pueraria lobata suppress alcohol preference in a pharmacogenetic rat model of alcoholism Alcoholism, Clinical and Experimental Research 20 1996 659 663
12. X.R. Lu, E. Gao, L.Z. Xu, H.Z. Li, B. Kang, W.N. Chen, S.M. Chen, and X.S. Chai Blocking effect of puerarin on beta-adrenoceptors of isolated organs and the whole animal Acta Pharmacologica Sinica 7 1986 537 539
13. M. Pinto, S. Robin-Leon, M. Appay, M. Kedinger, N. Triadou, E. Dussaulx, B. Lacroix, P. Simon-Assman, K. Haffen, J. Fogh, and A. Zweibaum Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture Biology of the Cell 47 1983 323 330
14. Z. Rashid, and M.D. Basson Topoisomerase II inhibition differentially modulates Caco-2 intestinal epithelial cell phenotype Biochemical and Biophysical Research Communications 219 1996 82 88
15. B.D. Rege, L.X. Yu, A.S. Hussain, and J.E. Polli Effect of common excipients on Caco-2 transport of low-permeability drugs Journal of Pharmaceutical Sciences 11 2001 1776 1785
16. X.Y. Sha, and X.L. Fang Transport characteristics of 9-nitrocamptothecin inthe human intestinal cell line Caco-2 and everted gut sacs International Journal of Pharmaceutics 272 2004 161 171
17. L. Song, N. Zhang, and D.S. Xu Absorption mechanism of paeoniflorin across Caco-2 monolayer model Chinese Traditional and Herbal Drugs 1 2008 41 44
18. M.J. Sun, X. Sheng, and Y. Hu Establishment and validation of Caco-2 cell lines for intestinal epithelial permeability Chinese Pharmaceutical Journal 18 2006 1431 1434
19. M. Takano, R. Yumoto, and T. Murakami Expression and function of efflux drug transporters in the intestine Pharmacology & Therapeutics 109 2006 137 161
20. G.A. Turowski, Z. Rashid, F. Hong, J.A. Madri, and M.D. Basson Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines Cancer Research 54 1994 5974 5980
21. J.B. Vaidyanathan, and T. Walle Transport and metabolism of the tea flavonoid (-)-epicatechin by the human intestinal cell line Caco-2 Pharmaceutical Research 18 2001 1420 1425
22. L.J. Xi, and W. Chen The mechanism of research summary of the decreasing toxicity and increasing efficacy on Radix Aconiti Lateralis Preparata concomitant with Rhizoma Zingiber Journal of Practical Traditional Chinese Medicine 9 2008 608 610
23. Q.H. Xu A comprehensive Chinese traditional medicine partner [M] 1996 China Press of Traditional Chinese Medicine Beijing 67-68
24. B. Xuan, Y.H. Zhou, R.L. Yang, N. Li, Z.D. Min, and G.C. Chou Improvementof ocular blood flow and retinal functions with puerarin analogs Journal of Ocular Pharmacology and Therapeutics 15 1999 207 216
25. Yu. Yuan Study on the preparation process and quality standard of effective part from Angelicadahurica (Fiseh.exHoffm.) Benth.et Hook Lva formosana(Boiss)[C] 2008 20 33
26. Y.J. Zhang, J. Yang.; X.C. Zou, L.M. Liu, and W.J. Sun Influence of match-pair of huanglian-rougui on rat intestinal absorption of total huanglian alkali China Journal of Chinese Materia Medica 15 2007 1521 1554
27. J. Zhao, and A.H. Liang Caco-2 Cell model and its application in the absorption and transportation research of chinese materia medica Chinese Journal of Experimental Traditional Medical Formulae 15 2009 79 82