메뉴 건너뛰기




Volumn 29, Issue 5, 2009, Pages 1480-1485

Rab11a and HSP90 regulate recycling of extracellular α-synuclein

Author keywords

synuclein; Exocytosis; HSP90; Parkinson's disease; Proteomics; rab11a; Synucleinopathy

Indexed keywords

ALPHA SYNUCLEIN; BIOLOGICAL MARKER; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; RAB11 PROTEIN; RAB11A PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 59649097036     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6202-08.2009     Document Type: Article
Times cited : (121)

References (26)
  • 3
    • 27344438938 scopus 로고    scopus 로고
    • Microglial inflammation in the parkinsonian substantia nigra: Relationship to alpha-synuclein deposition
    • Croisier E, Moran LB, Dexter DT, Pearce RK, Graeber MB (2005) Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition. J Neuroinflammation 2:14.
    • (2005) J Neuroinflammation , vol.2 , pp. 14
    • Croisier, E.1    Moran, L.B.2    Dexter, D.T.3    Pearce, R.K.4    Graeber, M.B.5
  • 4
    • 0032573597 scopus 로고    scopus 로고
    • Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments
    • El-Agnaf OM, Jakes R, Curran MD, Middleton D, Ingenito R, Bianchi E, Pessi A, Neill D, Wallace A (1998) Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments. FEBS Lett 440:71-75.
    • (1998) FEBS Lett , vol.440 , pp. 71-75
    • El-Agnaf, O.M.1    Jakes, R.2    Curran, M.D.3    Middleton, D.4    Ingenito, R.5    Bianchi, E.6    Pessi, A.7    Neill, D.8    Wallace, A.9
  • 6
    • 0034017710 scopus 로고    scopus 로고
    • Alpha-synuclein and Parkinson's disease: Selective neurodegenerative effect of alpha-synuclein fragment on dopaminergic neurons in vitro and in vivo
    • Forloni G, Bertani I, Calella AM, Thaler F, Invernizzi R (2000) Alpha-synuclein and Parkinson's disease: selective neurodegenerative effect of alpha-synuclein fragment on dopaminergic neurons in vitro and in vivo. Ann Neurol 47:632-640.
    • (2000) Ann Neurol , vol.47 , pp. 632-640
    • Forloni, G.1    Bertani, I.2    Calella, A.M.3    Thaler, F.4    Invernizzi, R.5
  • 9
    • 33750121865 scopus 로고    scopus 로고
    • Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells
    • Klegeris A, Giasson BI, Zhang H, Maguire J, Pelech S, McGeer PL (2006) Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells. FASEB J 20:2000-2008.
    • (2006) FASEB J , vol.20 , pp. 2000-2008
    • Klegeris, A.1    Giasson, B.I.2    Zhang, H.3    Maguire, J.4    Pelech, S.5    McGeer, P.L.6
  • 10
    • 43249114934 scopus 로고    scopus 로고
    • Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
    • Kordower JH, Chu Y, Hauser RA, Freeman TB, Olanow CW (2008) Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat Med 14:504-506.
    • (2008) Nat Med , vol.14 , pp. 504-506
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Freeman, T.B.4    Olanow, C.W.5
  • 12
    • 21344456506 scopus 로고    scopus 로고
    • Intravesicular localization and exocytosis of alpha-synuclein and its aggregates
    • Lee HJ, Patel S, Lee SJ (2005) Intravesicular localization and exocytosis of alpha-synuclein and its aggregates. J Neurosci 25:6016-6024.
    • (2005) J Neurosci , vol.25 , pp. 6016-6024
    • Lee, H.J.1    Patel, S.2    Lee, S.J.3
  • 14
    • 34948870903 scopus 로고    scopus 로고
    • Identification of proteins involved in microglial endocytosis of alpha-synuclein
    • Liu J, Zhou Y, Wang Y, Fong H, Murray TM, Zhang J (2007) Identification of proteins involved in microglial endocytosis of alpha-synuclein. J Proteome Res 6:3614-3627.
    • (2007) J Proteome Res , vol.6 , pp. 3614-3627
    • Liu, J.1    Zhou, Y.2    Wang, Y.3    Fong, H.4    Murray, T.M.5    Zhang, J.6
  • 15
    • 0036810352 scopus 로고    scopus 로고
    • Heat-shock protein 90, a chaperone for folding and regulation
    • Picard D (2002) Heat-shock protein 90, a chaperone for folding and regulation. Cell Mol Life Sci 59:1640-1648.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1640-1648
    • Picard, D.1
  • 16
    • 0029984860 scopus 로고    scopus 로고
    • Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity
    • Przedborski S, Jackson-Lewis V, Yokoyama R, Shibata T, Dawson VL, Dawson TM (1996) Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc Natl Acad Sci U S A 93:4565-4571.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4565-4571
    • Przedborski, S.1    Jackson-Lewis, V.2    Yokoyama, R.3    Shibata, T.4    Dawson, V.L.5    Dawson, T.M.6
  • 17
    • 0037110754 scopus 로고    scopus 로고
    • Rab-alphaGDI activity is regulated by a Hsp90 chaperone complex
    • Sakisaka T, Meerlo T, Matteson J, Plutner H, Balch WE (2002) Rab-alphaGDI activity is regulated by a Hsp90 chaperone complex. EMBO J 21:6125-6135.
    • (2002) EMBO J , vol.21 , pp. 6125-6135
    • Sakisaka, T.1    Meerlo, T.2    Matteson, J.3    Plutner, H.4    Balch, W.E.5
  • 18
    • 0036970672 scopus 로고    scopus 로고
    • Deferoxamine attenuates iron-induced oxidative stress and prevents mitochondrial aggregation and alpha-synuclein translocation in SK-N-SH cells in culture
    • Sangchot P, Sharma S, Chetsawang B, Porter J, Govitrapong P, Ebadi M (2002) Deferoxamine attenuates iron-induced oxidative stress and prevents mitochondrial aggregation and alpha-synuclein translocation in SK-N-SH cells in culture. Dev Neurosci 24:143-153.
    • (2002) Dev Neurosci , vol.24 , pp. 143-153
    • Sangchot, P.1    Sharma, S.2    Chetsawang, B.3    Porter, J.4    Govitrapong, P.5    Ebadi, M.6
  • 20
    • 0035920226 scopus 로고    scopus 로고
    • Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein
    • Sung JY, Kim J, Paik SR, Park JH, Ahn YS, Chung KC (2001) Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein. J Biol Chem 276:27441-27448.
    • (2001) J Biol Chem , vol.276 , pp. 27441-27448
    • Sung, J.Y.1    Kim, J.2    Paik, S.R.3    Park, J.H.4    Ahn, Y.S.5    Chung, K.C.6
  • 21
    • 18844472606 scopus 로고    scopus 로고
    • Role of the Rab11-associated intracellular pool of receptors formed by constitutive endocytosis of the beta isoform of the thromboxane A2 receptor (TP beta)
    • Thériault C, Rochdi MD, Parent JL (2004) Role of the Rab11-associated intracellular pool of receptors formed by constitutive endocytosis of the beta isoform of the thromboxane A2 receptor (TP beta). Biochemistry 43:5600-5607.
    • (2004) Biochemistry , vol.43 , pp. 5600-5607
    • Thériault, C.1    Rochdi, M.D.2    Parent, J.L.3
  • 23
    • 0036480017 scopus 로고    scopus 로고
    • Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells
    • van IJzendoorn SC, Tuvim MJ, Weimbs T, Dickey BF, Mostov KE (2002) Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells. Dev Cell 2:219-228.
    • (2002) Dev Cell , vol.2 , pp. 219-228
    • van IJzendoorn, S.C.1    Tuvim, M.J.2    Weimbs, T.3    Dickey, B.F.4    Mostov, K.E.5
  • 24
    • 0032911488 scopus 로고    scopus 로고
    • Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
    • Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ (1999) Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol 154:1423-1429.
    • (1999) Am J Pathol , vol.154 , pp. 1423-1429
    • Zhang, J.1    Perry, G.2    Smith, M.A.3    Robertson, D.4    Olson, S.J.5    Graham, D.G.6    Montine, T.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.