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Volumn 47, Issue 3, 2015, Pages

Sleep, circadian rhythms, and the pathogenesis of Alzheimer Disease

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANIMAL; CIRCADIAN RHYTHM; DISEASE MODEL; HUMAN; MOUSE; SLEEP;

EID: 84989315906     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/EMM.2014.121     Document Type: Article
Times cited : (391)

References (92)
  • 1
    • 84893829393 scopus 로고    scopus 로고
    • Sleep and Alzheimer disease pathology–a bidirectional relationship
    • Ju YE, Lucey BP, Holtzman DM. Sleep and Alzheimer disease pathology–a bidirectional relationship. Nat Rev Neurol 2014; 10: 115–119.
    • (2014) Nat Rev Neurol , vol.10 , pp. 115-119
    • Ju, Y.E.1    Lucey, B.P.2    Holtzman, D.M.3
  • 3
    • 2442502760 scopus 로고    scopus 로고
    • Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia
    • Hatfield CF, Herbert J, van Someren EJ, Hodges JR, Hastings MH. Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia. Brain 2004; 127: 1061–1074.
    • (2004) Brain , vol.127 , pp. 1061-1074
    • Hatfield, C.F.1    Herbert, J.2    van Someren, E.J.3    Hodges, J.R.4    Hastings, M.H.5
  • 8
    • 84865955498 scopus 로고    scopus 로고
    • Disruption of the sleep-wake cycle and diurnal fluctuation of beta-amyloid in mice with Alzheimer's disease pathology
    • Roh JH, Huang Y, Bero AW, Kasten T, Stewart FR, Bateman RJ et al. Disruption of the sleep-wake cycle and diurnal fluctuation of beta-amyloid in mice with Alzheimer's disease pathology. Sci Transl Med 2012; 4: 150ra122.
    • (2012) Sci Transl Med , vol.4 , pp. 150ra122
    • Roh, J.H.1    Huang, Y.2    Bero, A.W.3    Kasten, T.4    Stewart, F.R.5    Bateman, R.J.6
  • 9
    • 84861866541 scopus 로고    scopus 로고
    • Effects of aging and genotype on circadian rhythms, sleep, and clock gene expression in APPxPS1 knock-in mice, a model for Alzheimer's disease
    • Duncan MJ, Smith JT, Franklin KM, Beckett TL, Murphy MP, St Clair DK et al. Effects of aging and genotype on circadian rhythms, sleep, and clock gene expression in APPxPS1 knock-in mice, a model for Alzheimer's disease. Exp Neurol 2012; 236: 249–258.
    • (2012) Exp Neurol , vol.236 , pp. 249-258
    • Duncan, M.J.1    Smith, J.T.2    Franklin, K.M.3    Beckett, T.L.4    Murphy, M.P.5    St Clair, D.K.6
  • 10
    • 77955714612 scopus 로고    scopus 로고
    • Characterization of the 3xTg-AD mouse model of Alzheimer's disease: Part 1. Circadian changes
    • Sterniczuk R, Dyck RH, Laferla FM, Antle MC. Characterization of the 3xTg-AD mouse model of Alzheimer's disease: part 1. Circadian changes. Brain Res 2010; 1348: 139–148.
    • (2010) Brain Res , vol.1348 , pp. 139-148
    • Sterniczuk, R.1    Dyck, R.H.2    Laferla, F.M.3    Antle, M.C.4
  • 11
    • 78650644126 scopus 로고    scopus 로고
    • EEG, activity, and sleep architecture in a transgenic AbetaPPswe/PSEN1A246E Alzheimer's disease mouse
    • Jyoti A, Plano A, Riedel G, Platt B. EEG, activity, and sleep architecture in a transgenic AbetaPPswe/PSEN1A246E Alzheimer's disease mouse. JAlz-heimers Dis 2010; 22: 873–887.
    • (2010) Jalz-Heimers Dis , vol.22 , pp. 873-887
    • Jyoti, A.1    Plano, A.2    Riedel, G.3    Platt, B.4
  • 12
    • 80855156783 scopus 로고    scopus 로고
    • Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse
    • Platt B, Drever B, Koss D, Stoppelkamp S, Jyoti A, Plano A et al. Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1. PLoS ONE 2011; 6: e27068.
    • (2011) PLB1. Plos ONE , vol.6
    • Platt, B.1    Drever, B.2    Koss, D.3    Stoppelkamp, S.4    Jyoti, A.5    Plano, A.6
  • 13
    • 13544275103 scopus 로고    scopus 로고
    • Sleep and circadian abnormalities in a transgenic mouse model of Alzheimer's disease: A role for cholinergic transmission
    • Wisor JP, Edgar DM, Yesavage J, Ryan HS, McCormick CM, Lapustea N et al. Sleep and circadian abnormalities in a transgenic mouse model of Alzheimer's disease: a role for cholinergic transmission. Neuroscience 2005; 131: 375–385.
    • (2005) Neuroscience , vol.131 , pp. 375-385
    • Wisor, J.P.1    Edgar, D.M.2    Yesavage, J.3    Ryan, H.S.4    McCormick, C.M.5    Lapustea, N.6
  • 14
    • 27544500099 scopus 로고    scopus 로고
    • Impaired rapid eye movement sleep in the Tg2576 APP murine model of Alzheimer's disease with injury to pedunculopontine cholinergic neurons
    • Zhang B, Veasey SC, Wood MA, Leng LZ, Kaminski C, Leight S et al. Impaired rapid eye movement sleep in the Tg2576 APP murine model of Alzheimer's disease with injury to pedunculopontine cholinergic neurons. Am J Pathol 2005; 167: 1361–1369.
    • (2005) Am J Pathol , vol.167 , pp. 1361-1369
    • Zhang, B.1    Veasey, S.C.2    Wood, M.A.3    Leng, L.Z.4    Kaminski, C.5    Leight, S.6
  • 16
    • 84887410206 scopus 로고    scopus 로고
    • Sleep disturbance is associated with incident dementia and mortality
    • Sterniczuk R, Theou O, Rusak B, Rockwood K. Sleep disturbance is associated with incident dementia and mortality. Curr Alzheimer Res 2013; 10: 767–775.
    • (2013) Curr Alzheimer Res , vol.10 , pp. 767-775
    • Sterniczuk, R.1    Theou, O.2    Rusak, B.3    Rockwood, K.4
  • 17
    • 84859818522 scopus 로고    scopus 로고
    • Sleep quality and 1-year incident cognitive impairment in community-dwelling older adults
    • Potvin O, Lorrain D, Forget H, Dube M, Grenier S, Preville M et al. Sleep quality and 1-year incident cognitive impairment in community-dwelling older adults. Sleep 2012; 35: 491–499.
    • (2012) Sleep , vol.35 , pp. 491-499
    • Potvin, O.1    Lorrain, D.2    Forget, H.3    Dube, M.4    Grenier, S.5    Preville, M.6
  • 19
    • 84887111135 scopus 로고    scopus 로고
    • Measuring sleep: Accuracy, sensitivity, and specificity of wrist actigraphy compared to polysomnography
    • Marino M, Li Y, Rueschman MN, Winkelman JW, Ellenbogen JM, Solet JM et al. Measuring sleep: accuracy, sensitivity, and specificity of wrist actigraphy compared to polysomnography. Sleep 2013; 36: 1747–1755.
    • (2013) Sleep , vol.36 , pp. 1747-1755
    • Marino, M.1    Li, Y.2    Rueschman, M.N.3    Winkelman, J.W.4    Ellenbogen, J.M.5    Solet, J.M.6
  • 20
    • 84860622663 scopus 로고    scopus 로고
    • Increased fragmentation of rest-activity patterns is associated with a characteristic pattern of cognitive impairment in older individuals
    • Lim AS, Yu L, Costa MD, Leurgans SE, Buchman AS, Bennett DA et al. Increased fragmentation of rest-activity patterns is associated with a characteristic pattern of cognitive impairment in older individuals. Sleep 2012; 35: 633–640B.
    • (2012) Sleep , vol.35 , pp. 633-640
    • Lim, A.S.1    Yu, L.2    Costa, M.D.3    Leurgans, S.E.4    Buchman, A.S.5    Bennett, D.A.6
  • 21
    • 84879656270 scopus 로고    scopus 로고
    • Sleep fragmentation and the risk of incident Alzheimer's disease and cognitive decline in older persons
    • Lim AS, Kowgier M, Yu L, Buchman AS, Bennett DA. Sleep fragmentation and the risk of incident Alzheimer's disease and cognitive decline in older persons. Sleep 2013; 36: 1027–1032.
    • (2013) Sleep , vol.36 , pp. 1027-1032
    • Lim, A.S.1    Kowgier, M.2    Yu, L.3    Buchman, A.S.4    Bennett, D.A.5
  • 22
    • 84890413875 scopus 로고    scopus 로고
    • Modification of the relationship of the apolipoprotein E epsilon4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep
    • Lim AS, Yu L, Kowgier M, Schneider JA, Buchman AS, Bennett DA. Modification of the relationship of the apolipoprotein E epsilon4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep. JAMA Neurol 2013; 70: 1544–1551.
    • (2013) JAMA Neurol , vol.70 , pp. 1544-1551
    • Lim, A.S.1    Yu, L.2    Kowgier, M.3    Schneider, J.A.4    Buchman, A.S.5    Bennett, D.A.6
  • 24
    • 84890358370 scopus 로고    scopus 로고
    • Self-reported sleep and beta-amyloid deposition in community-dwelling older adults
    • Spira AP, Gamaldo AA, An Y, Wu MN, Simonsick EM, Bilgel M et al. Self-reported sleep and beta-amyloid deposition in community-dwelling older adults. JAMA Neurol 2013; 70: 1537–1543.
    • (2013) JAMA Neurol , vol.70 , pp. 1537-1543
    • Spira, A.P.1    Gamaldo, A.A.2    An, Y.3    Wu, M.N.4    Simonsick, E.M.5    Bilgel, M.6
  • 25
    • 72449161215 scopus 로고    scopus 로고
    • Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle
    • Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR et al. Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle. Science 2009; 326: 1005–1007.
    • (2009) Science , vol.326 , pp. 1005-1007
    • Kang, J.E.1    Lim, M.M.2    Bateman, R.J.3    Lee, J.J.4    Smyth, L.P.5    Cirrito, J.R.6
  • 26
    • 84862908271 scopus 로고    scopus 로고
    • Effects of age and amyloid deposition on Abeta dynamics in the human central nervous system
    • Huang Y, Potter R, Sigurdson W, Santacruz A, Shih S, Ju YE et al. Effects of age and amyloid deposition on Abeta dynamics in the human central nervous system. Arch Neurol 2012; 69: 51–58.
    • (2012) Arch Neurol , vol.69 , pp. 51-58
    • Huang, Y.1    Potter, R.2    Sigurdson, W.3    Santacruz, A.4    Shih, S.5    Ju, Y.E.6
  • 29
    • 79960809092 scopus 로고    scopus 로고
    • Neuronal activity regulates the regional vulnerability to amyloid-beta deposition
    • Bero AW, Yan P, Roh JH, Cirrito JR, Stewart FR, Raichle ME et al. Neuronal activity regulates the regional vulnerability to amyloid-beta deposition. Nat Neurosci 2011; 14: 750–756.
    • (2011) Nat Neurosci , vol.14 , pp. 750-756
    • Bero, A.W.1    Yan, P.2    Roh, J.H.3    Cirrito, J.R.4    Stewart, F.R.5    Raichle, M.E.6
  • 31
    • 84885775321 scopus 로고    scopus 로고
    • Sleep drives metabolite clearance from the adult brain
    • Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Thiyagarajan M et al. Sleep drives metabolite clearance from the adult brain. Science 2013; 342: 373–377.
    • (2013) Science , vol.342 , pp. 373-377
    • Xie, L.1    Kang, H.2    Xu, Q.3    Chen, M.J.4    Liao, Y.5    Thiyagarajan, M.6
  • 32
    • 84882580016 scopus 로고    scopus 로고
    • Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Abeta and pTau in a mouse model of Alzheimer's disease
    • Rothman SM, Herdener N, Frankola KA, Mughal MR, Mattson MP. Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Abeta and pTau in a mouse model of Alzheimer's disease. Brain Res 2013; 1529: 200–208.
    • (2013) Brain Res , vol.1529 , pp. 200-208
    • Rothman, S.M.1    Herdener, N.2    Frankola, K.A.3    Mughal, M.R.4    Mattson, M.P.5
  • 33
    • 33748253471 scopus 로고    scopus 로고
    • Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease
    • Green KN, Billings LM, Roozendaal B, McGaugh JL, LaFerla FM. Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease. JNeurosci2006; 26: 9047–9056.
    • Jneurosci2006 , vol.26 , pp. 9047-9056
    • Green, K.N.1    Billings, L.M.2    Roozendaal, B.3    McGaugh, J.L.4    Laferla, F.M.5
  • 34
    • 34547496875 scopus 로고    scopus 로고
    • Acute stress increases interstitial fluid amyloid-beta via corticotropin-releasing factor and neuronal activity
    • Kang JE, Cirrito JR, Dong H, Csernansky JG, Holtzman DM. Acute stress increases interstitial fluid amyloid-beta via corticotropin-releasing factor and neuronal activity. Proc Natl Acad Sci USA 2007; 104: 10673–10678.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 10673-10678
    • Kang, J.E.1    Cirrito, J.R.2    Dong, H.3    Csernansky, J.G.4    Holtzman, D.M.5
  • 35
    • 47249123586 scopus 로고    scopus 로고
    • Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice
    • Dong H, Yuede CM, Yoo HS, Martin MV, Deal C, Mace AG et al. Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice. Neuroscience 2008; 155: 154–163.
    • (2008) Neuroscience , vol.155 , pp. 154-163
    • Dong, H.1    Yuede, C.M.2    Yoo, H.S.3    Martin, M.V.4    Deal, C.5    Mace, A.G.6
  • 37
    • 84905994853 scopus 로고    scopus 로고
    • Effect of 1 night of total sleep deprivation on cerebrospinal fluid beta-Amyloid 42 in healthy middle-aged men: A randomized clinical trial
    • Ooms S, Overeem S, Besse K, Rikkert MO, Verbeek M, Claassen JA. Effect of 1 night of total sleep deprivation on cerebrospinal fluid beta-Amyloid 42 in healthy middle-aged men: a randomized clinical trial. JAMA Neurol 2014; 71: 971–977.
    • (2014) JAMA Neurol , vol.71 , pp. 971-977
    • Ooms, S.1    Overeem, S.2    Besse, K.3    Rikkert, M.O.4    Verbeek, M.5    Claassen, J.A.6
  • 38
    • 84899939418 scopus 로고    scopus 로고
    • Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles
    • Di Meco A, Joshi YB, Pratico D. Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles. Neurobiol Aging 2014; 35: 1813–1820.
    • (2014) Neurobiol Aging , vol.35 , pp. 1813-1820
    • Di Meco, A.1    Joshi, Y.B.2    Pratico, D.3
  • 39
    • 84891793558 scopus 로고    scopus 로고
    • Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men
    • Benedict C, Cedernaes J, Giedraitis V, Nilsson EK, Hogenkamp PS, Vagesjo E et al. Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men. Sleep 2014; 37: 195–198.
    • (2014) Sleep , vol.37 , pp. 195-198
    • Benedict, C.1    Cedernaes, J.2    Giedraitis, V.3    Nilsson, E.K.4    Hogenkamp, P.S.5    Vagesjo, E.6
  • 40
    • 84896304908 scopus 로고    scopus 로고
    • Extended wakefulness: Compromised metabolics in and degeneration of locus ceruleus neurons
    • Zhang J, Zhu Y, Zhan G, Fenik P, Panossian L, Wang MM et al. Extended wakefulness: compromised metabolics in and degeneration of locus ceruleus neurons. JNeurosci2014; 34: 4418–4431.
    • (2014) Jneurosci , vol.34 , pp. 4418-4431
    • Zhang, J.1    Zhu, Y.2    Zhan, G.3    Fenik, P.4    Panossian, L.5    Wang, M.M.6
  • 41
    • 48549090526 scopus 로고    scopus 로고
    • Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling
    • Naidoo N, Ferber M, Master M, Zhu Y, Pack AI. Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling. JNeurosci2008; 28: 6539–6548.
    • (2008) Jneurosci , vol.28 , pp. 6539-6548
    • Naidoo, N.1    Ferber, M.2    Master, M.3    Zhu, Y.4    Pack, A.I.5
  • 42
    • 14844288931 scopus 로고    scopus 로고
    • Sleep deprivation induces the unfolded protein response in mouse cerebral cortex
    • Naidoo N, Giang W, Galante RJ, Pack AI. Sleep deprivation induces the unfolded protein response in mouse cerebral cortex. JNeurochem2005; 92: 1150–1157.
    • (2005) Jneurochem , vol.92 , pp. 1150-1157
    • Naidoo, N.1    Giang, W.2    Galante, R.J.3    Pack, A.I.4
  • 43
    • 69449102408 scopus 로고    scopus 로고
    • Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice
    • Yan P, Bero AW, Cirrito JR, Xiao Q, Hu X, Wang Y et al. Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice. JNeurosci 2009; 29: 10706–10714.
    • (2009) Jneurosci , vol.29 , pp. 10706-10714
    • Yan, P.1    Bero, A.W.2    Cirrito, J.R.3    Xiao, Q.4    Hu, X.5    Wang, Y.6
  • 44
    • 0032044191 scopus 로고    scopus 로고
    • The suprachiasmatic nucleus: A 25-year retrospective
    • Weaver DR. The suprachiasmatic nucleus: a 25-year retrospective. JBiol Rhythms 1998; 13: 100–112.
    • (1998) Jbiol Rhythms , vol.13 , pp. 100-112
    • Weaver, D.R.1
  • 45
  • 49
    • 84912040804 scopus 로고    scopus 로고
    • The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated supra-chiasmatic nucleus clock
    • Husse J, Leliavski A, Tsang AH, Oster H, Eichele G. The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated supra-chiasmatic nucleus clock. FASEB J 2014; 28: 4950–4960.
    • (2014) FASEB J , vol.28 , pp. 4950-4960
    • Husse, J.1    Leliavski, A.2    Tsang, A.H.3    Oster, H.4    Eichele, G.5
  • 52
    • 78649687209 scopus 로고    scopus 로고
    • Circadian integration of metabolism and energetics
    • Bass J, Takahashi JS. Circadian integration of metabolism and energetics. Science 2010; 330: 1349–1354.
    • (2010) Science , vol.330 , pp. 1349-1354
    • Bass, J.1    Takahashi, J.S.2
  • 53
    • 84896723156 scopus 로고    scopus 로고
    • Health consequences of circadian disruption in humans and animal models
    • Evans JA, Davidson AJ. Health consequences of circadian disruption in humans and animal models. Prog Mol Biol Transl Sci 2013; 119: 283–323.
    • (2013) Prog Mol Biol Transl Sci , vol.119 , pp. 283-323
    • Evans, J.A.1    Davidson, A.J.2
  • 55
    • 16844370426 scopus 로고    scopus 로고
    • Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation
    • Laposky A, Easton A, Dugovic C, Walisser J, Bradfield C, Turek F. Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation. Sleep 2005; 28: 395–409.
    • (2005) Sleep , vol.28 , pp. 395-409
    • Laposky, A.1    Easton, A.2    Dugovic, C.3    Walisser, J.4    Bradfield, C.5    Turek, F.6
  • 56
    • 80055030043 scopus 로고    scopus 로고
    • Sleep loss reduces the DNA-binding of BMAL1, CLOCK, and NPAS2 to specific clock genes in the mouse cerebral cortex
    • Mongrain V, La Spada F, Curie T, Franken P. Sleep loss reduces the DNA-binding of BMAL1, CLOCK, and NPAS2 to specific clock genes in the mouse cerebral cortex. PLoS ONE 2011; 6: e26622.
    • (2011) Plos ONE , vol.6
    • Mongrain, V.1    la Spada, F.2    Curie, T.3    Franken, P.4
  • 57
    • 84879391795 scopus 로고    scopus 로고
    • SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging
    • Chang HC, Guarente L. SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging. Cell 2013; 153: 1448–1460.
    • (2013) Cell , vol.153 , pp. 1448-1460
    • Chang, H.C.1    Guarente, L.2
  • 58
    • 0025238507 scopus 로고
    • Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease
    • Witting W, Kwa IH, Eikelenboom P, Mirmiran M, Swaab DF. Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease. Biol Psychiatry 1990; 27: 563–572.
    • (1990) Biol Psychiatry , vol.27 , pp. 563-572
    • Witting, W.1    Kwa, I.H.2    Eikelenboom, P.3    Mirmiran, M.4    Swaab, D.F.5
  • 59
    • 84882270256 scopus 로고    scopus 로고
    • The circadian system in Alzheimer's disease: Disturbances, mechanisms, and opportunities
    • Coogan AN, Schutova B, Husung S, Furczyk K, Baune BT, Kropp P et al. The circadian system in Alzheimer's disease: disturbances, mechanisms, and opportunities. Biol Psychiatry 2013; 74: 333–339.
    • (2013) Biol Psychiatry , vol.74 , pp. 333-339
    • Coogan, A.N.1    Schutova, B.2    Husung, S.3    Furczyk, K.4    Baune, B.T.5    Kropp, P.6
  • 60
    • 62449216579 scopus 로고    scopus 로고
    • Reduction of scale invariance of activity fluctuations with aging and Alzheimer's disease: Involvement of the circadian pacemaker
    • Hu K, Van Someren EJ, Shea SA, Scheer FA. Reduction of scale invariance of activity fluctuations with aging and Alzheimer's disease: involvement of the circadian pacemaker. Proc Natl Acad Sci USA 2009; 106: 2490–2494.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2490-2494
    • Hu, K.1    van Someren, E.J.2    Shea, S.A.3    Scheer, F.A.4
  • 61
    • 33845572904 scopus 로고    scopus 로고
    • Pineal clock gene oscillation is disturbed in Alzheimer's disease, due to functional disconnection from the "master clock"
    • Wu YH, Fischer DF, Kalsbeek A, Garidou-Boof ML, van der Vliet J, van Heijningen C et al. Pineal clock gene oscillation is disturbed in Alzheimer's disease, due to functional disconnection from the "master clock". FASEB J 2006; 20: 1874–1876.
    • (2006) FASEB J , vol.20 , pp. 1874-1876
    • Wu, Y.H.1    Fischer, D.F.2    Kalsbeek, A.3    Garidou-Boof, M.L.4    van der Vliet, J.5    van Heijningen, C.6
  • 62
    • 0037244324 scopus 로고    scopus 로고
    • Melatonin rhythmicity: Effect of age and Alzheimer's disease
    • Skene DJ, Swaab DF. Melatonin rhythmicity: effect of age and Alzheimer's disease. Exp Gerontol 2003; 38: 199–206.
    • (2003) Exp Gerontol , vol.38 , pp. 199-206
    • Skene, D.J.1    Swaab, D.F.2
  • 63
    • 84897941947 scopus 로고    scopus 로고
    • The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer's disease
    • Chen KF, Possidente B, Lomas DA, Crowther DC. The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer's disease. Dis Model Mech 2014; 7: 445–458.
    • (2014) Dis Model Mech , vol.7 , pp. 445-458
    • Chen, K.F.1    Possidente, B.2    Lomas, D.A.3    Crowther, D.C.4
  • 65
    • 44949090437 scopus 로고    scopus 로고
    • Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia
    • Harper DG, Stopa EG, Kuo-Leblanc V, McKee AC, Asayama K, Volicer L et al. Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia. Brain 2008; 131: 1609–1617.
    • (2008) Brain , vol.131 , pp. 1609-1617
    • Harper, D.G.1    Stopa, E.G.2    Kuo-Leblanc, V.3    McKee, A.C.4    Asayama, K.5    Volicer, L.6
  • 66
    • 0022347706 scopus 로고
    • The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia
    • Swaab DF, Fliers E, Partiman TS. The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia. Brain Res 1985; 342: 37–44.
    • (1985) Brain Res , vol.342 , pp. 37-44
    • Swaab, D.F.1    Fliers, E.2    Partiman, T.S.3
  • 67
    • 0029121750 scopus 로고
    • VIP neurons in the human SCN in relation to sex, age, and Alzheimer's disease
    • Zhou JN, Hofman MA, Swaab DF. VIP neurons in the human SCN in relation to sex, age, and Alzheimer's disease. Neurobiol Aging 1995; 16: 571–576.
    • (1995) Neurobiol Aging , vol.16 , pp. 571-576
    • Zhou, J.N.1    Hofman, M.A.2    Swaab, D.F.3
  • 69
    • 33645287357 scopus 로고    scopus 로고
    • Cellular senescence impairs circadian expression of clock genes in vitro and in vivo
    • Kunieda T, Minamino T, Katsuno T, Tateno K, Nishi J, Miyauchi H et al. Cellular senescence impairs circadian expression of clock genes in vitro and in vivo. Circ Res 2006; 98: 532–539.
    • (2006) Circ Res , vol.98 , pp. 532-539
    • Kunieda, T.1    Minamino, T.2    Katsuno, T.3    Tateno, K.4    Nishi, J.5    Miyauchi, H.6
  • 70
    • 77952552718 scopus 로고    scopus 로고
    • Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain
    • Wyse CA, Coogan AN. Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain. Brain Res 2010; 1337: 21–31.
    • (2010) Brain Res , vol.1337 , pp. 21-31
    • Wyse, C.A.1    Coogan, A.N.2
  • 71
    • 83255175636 scopus 로고    scopus 로고
    • Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women
    • Tranah GJ, Blackwell T, Stone KL, Ancoli-Israel S, Paudel ML, Ensrud KE et al. Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women. Ann Neurol 2011; 70: 722–732.
    • (2011) Ann Neurol , vol.70 , pp. 722-732
    • Tranah, G.J.1    Blackwell, T.2    Stone, K.L.3    Ancoli-Israel, S.4    Paudel, M.L.5    Ensrud, K.E.6
  • 72
    • 84876819617 scopus 로고    scopus 로고
    • Polymorphism of CLOCK gene rs 4580704 C4G is associated with susceptibility of Alzheimer's disease in a Chinese population
    • Chen HF, Huang CQ, You C, Wang ZR, Si-qing H. Polymorphism of CLOCK gene rs 4580704 C4G is associated with susceptibility of Alzheimer's disease in a Chinese population. Arch Med Res 2013; 44: 203–207.
    • (2013) Arch Med Res , vol.44 , pp. 203-207
    • Chen, H.F.1    Huang, C.Q.2    You, C.3    Wang, Z.R.4    Si-Qing, H.5
  • 73
    • 84878372382 scopus 로고    scopus 로고
    • Functional CLOCK gene rs1554483 G/C polymorphism is associated with susceptibility to Alzheimer's disease in the Chinese population
    • Chen Q, Huang CQ, Hu XY, Li SB, Zhang XM. Functional CLOCK gene rs1554483 G/C polymorphism is associated with susceptibility to Alzheimer's disease in the Chinese population. J Int Med Res 2013; 41: 340–346.
    • (2013) J Int Med Res , vol.41 , pp. 340-346
    • Chen, Q.1    Huang, C.Q.2    Hu, X.Y.3    Li, S.B.4    Zhang, X.M.5
  • 74
    • 84888258124 scopus 로고    scopus 로고
    • The polymorphism of CLOCK gene 3111 T/C C4T is associated with susceptibility of Alzheimer disease in Chinese population
    • Yang YK, Peng XD, Li YH, Wang ZR, Chang-quan H, Hui W et al. The polymorphism of CLOCK gene 3111 T/C C4T is associated with susceptibility of Alzheimer disease in Chinese population. J Investig Med 2013; 61: 1084–1087.
    • (2013) J Investig Med , vol.61 , pp. 1084-1087
    • Yang, Y.K.1    Peng, X.D.2    Li, Y.H.3    Wang, Z.R.4    Chang-Quan, H.5    Hui, W.6
  • 75
    • 84890015150 scopus 로고    scopus 로고
    • Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration
    • Musiek ES, Lim MM, Yang G, Bauer AQ, Qi L, Lee Y et al. Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. JClin Invest 2013; 123: 5389–5400.
    • (2013) Jclin Invest , vol.123 , pp. 5389-5400
    • Musiek, E.S.1    Lim, M.M.2    Yang, G.3    Bauer, A.Q.4    Qi, L.5    Lee, Y.6
  • 76
    • 79960380554 scopus 로고    scopus 로고
    • Melatonin as a natural ally against oxidative stress: A physicochemical examination
    • Galano A, Tan DX, Reiter RJ. Melatonin as a natural ally against oxidative stress: a physicochemical examination. JPinealRes2011; 51: 1–16.
    • Jpinealres2011 , vol.51 , pp. 1-16
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 78
    • 0042090064 scopus 로고    scopus 로고
    • Early neuro-pathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels
    • Zhou JN, Liu RY, Kamphorst W, Hofman MA, Swaab DF. Early neuro-pathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels. JPinealRes2003; 35: 125–130.
    • (2003) Jpinealres , vol.35 , pp. 125-130
    • Zhou, J.N.1    Liu, R.Y.2    Kamphorst, W.3    Hofman, M.A.4    Swaab, D.F.5
  • 79
    • 34848894332 scopus 로고    scopus 로고
    • Possible therapeutic value of melatonin in mild cognitive impairment: A retrospective study
    • Furio AM, Brusco LI, Cardinali DP. Possible therapeutic value of melatonin in mild cognitive impairment: a retrospective study. JPinealRes2007; 43: 404–409.
    • (2007) Jpinealres , vol.43 , pp. 404-409
    • Furio, A.M.1    Brusco, L.I.2    Cardinali, D.P.3
  • 80
    • 14944341045 scopus 로고    scopus 로고
    • Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: Implications for clinical trials
    • Quinn J, Kulhanek D, Nowlin J, Jones R, Pratico D, Rokach J et al. Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials. Brain Res 2005; 1037: 209–213.
    • (2005) Brain Res , vol.1037 , pp. 209-213
    • Quinn, J.1    Kulhanek, D.2    Nowlin, J.3    Jones, R.4    Pratico, D.5    Rokach, J.6
  • 81
    • 67649905028 scopus 로고    scopus 로고
    • Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease
    • Olcese JM, Cao C, Mori T, Mamcarz MB, Maxwell A, Runfeldt MJ et al. Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease. JPinealRes2009; 47: 82–96.
    • (2009) Jpinealres , vol.47 , pp. 82-96
    • Olcese, J.M.1    Cao, C.2    Mori, T.3    Mamcarz, M.B.4    Maxwell, A.5    Runfeldt, M.J.6
  • 82
    • 28744450569 scopus 로고    scopus 로고
    • Early melatonin supplementation alleviates oxidative stress in a transgenic mouse model of Alzheimer's disease
    • Feng Z, Qin C, Chang Y, Zhang JT. Early melatonin supplementation alleviates oxidative stress in a transgenic mouse model of Alzheimer's disease. Free Radic Biol Med 2006; 40: 101–109.
    • (2006) Free Radic Biol Med , vol.40 , pp. 101-109
    • Feng, Z.1    Qin, C.2    Chang, Y.3    Zhang, J.T.4
  • 85
    • 60849138397 scopus 로고    scopus 로고
    • Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease
    • Gehrman PR, Connor DJ, Martin JL, Shochat T, Corey-Bloom J, Ancoli-Israel S. Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease. Am J Geriatr Psychiatry 2009; 17: 166–169.
    • (2009) Am J Geriatr Psychiatry , vol.17 , pp. 166-169
    • Gehrman, P.R.1    Connor, D.J.2    Martin, J.L.3    Shochat, T.4    Corey-Bloom, J.5    Ancoli-Israel, S.6
  • 86
    • 0346490300 scopus 로고    scopus 로고
    • A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease
    • Singer C, Tractenberg RE, Kaye J, Schafer K, Gamst A, Grundman M et al. A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease. Sleep 2003; 26: 893–901.
    • (2003) Sleep , vol.26 , pp. 893-901
    • Singer, C.1    Tractenberg, R.E.2    Kaye, J.3    Schafer, K.4    Gamst, A.5    Grundman, M.6
  • 87
    • 0030917786 scopus 로고    scopus 로고
    • Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients
    • Van Someren EJ, Kessler A, Mirmiran M, Swaab DF. Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients. Biol Psychiatry 1997; 41: 955–963.
    • (1997) Biol Psychiatry , vol.41 , pp. 955-963
    • van Someren, E.J.1    Kessler, A.2    Mirmiran, M.3    Swaab, D.F.4
  • 88
    • 38549135428 scopus 로고    scopus 로고
    • Melatonin and bright-light treatment for rest-activity disruption in institutionalized patients with Alzheimer's disease
    • Dowling GA, Burr RL, Van Someren EJ, Hubbard EM, Luxenberg JS, Mastick J et al. Melatonin and bright-light treatment for rest-activity disruption in institutionalized patients with Alzheimer's disease. J Am Geriatr Soc 2008; 56: 239–246.
    • (2008) J am Geriatr Soc , vol.56 , pp. 239-246
    • Dowling, G.A.1    Burr, R.L.2    van Someren, E.J.3    Hubbard, E.M.4    Luxenberg, J.S.5    Mastick, J.6
  • 89
    • 44949175084 scopus 로고    scopus 로고
    • Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: A randomized controlled trial
    • Riemersma-van der Lek RF, Swaab DF, Twisk J, Hol EM, Hoogendijk WJ, Van Someren EJ. Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial. JAMA 2008; 299: 2642–2655.
    • (2008) JAMA , vol.299 , pp. 2642-2655
    • Riemersma-Van der Lek, R.F.1    Swaab, D.F.2    Twisk, J.3    Hol, E.M.4    Hoogendijk, W.J.5    van Someren, E.J.6
  • 90
    • 78650432933 scopus 로고    scopus 로고
    • High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIalpha as a clock regulatory kinase
    • Hirota T, Lee JW, Lewis WG, Zhang EE, Breton G, Liu X et al. High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIalpha as a clock regulatory kinase. PLoS Biol 2010; 8: e1000559.
    • (2010) Plos Biol , vol.8
    • Hirota, T.1    Lee, J.W.2    Lewis, W.G.3    Zhang, E.E.4    Breton, G.5    Liu, X.6
  • 91
    • 84862909015 scopus 로고    scopus 로고
    • Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening
    • Chen Z, Yoo SH, Park YS, Kim KH, Wei S, Buhr E et al. Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening. Proc Natl Acad Sci USA 2012; 109: 101–106.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 101-106
    • Chen, Z.1    Yoo, S.H.2    Park, Y.S.3    Kim, K.H.4    Wei, S.5    Buhr, E.6
  • 92
    • 84860291442 scopus 로고    scopus 로고
    • Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists
    • Solt LA, Wang Y, Banerjee S, Hughes T, Kojetin DJ, Lundasen T et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature 2012; 485: 62–68.
    • (2012) Nature , vol.485 , pp. 62-68
    • Solt, L.A.1    Wang, Y.2    Banerjee, S.3    Hughes, T.4    Kojetin, D.J.5    Lundasen, T.6


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