Cellular senescence impairs circadian expression of clock genes in vitro and in vivo

Circulation Research

Volumn 98, Issue 4, 2006, Pages 532-539

  Kunieda, Takeshige ^a   Minamino, Tohru ^a   Katsuno, Taro ^a   Tateno, Kaoru ^a   Nishi, Jun Ichiro ^a   Miyauchi, Hideyuki ^a   Orimo, Masayuki ^a   Okada, Sho ^a   Komuro, Issei ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Aging; Clock gene; CREB; ERK; Senescence

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORSKOLIN; MITOGEN ACTIVATED PROTEIN KINASE P38; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; SB 209030; TELOMERASE; UNCLASSIFIED DRUG; CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR CLOCK;

AGE; ARTICLE; CIRCADIAN RHYTHM; CLOCK GENE; CONTROLLED STUDY; FEEDBACK SYSTEM; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; OSCILLATION; PRIORITY JOURNAL; SENESCENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; CELL AGING; CELL CULTURE; CYTOLOGY; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; SMOOTH MUSCLE FIBER; TELOMERE; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL AGING; CELLS, CULTURED; CIRCADIAN RHYTHM; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TELOMERE; TRANS-ACTIVATORS;

EID: 33645287357     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000204504.25798.a8     Document Type: Article

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