Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles

Neurobiology of Aging

Volumn 35, Issue 8, 2014, Pages 1813-1820

  Di Meco, Antonio ^a   Joshi, Yash B ^a   Praticò, Domenico ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Amyloid beta; Behavior; Sleep deprivation; Synapse; Tau protein; Transgenic mouse model

Indexed keywords

AMYLOID BETA PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; TAU PROTEIN; TRANSCRIPTION FACTOR; DLGH4 PROTEIN, MOUSE; GUANYLATE KINASE; MEMBRANE PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC STRESS; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE COURSE; LEARNING; MEMORY; MEMORY DISORDER; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PATHOGENESIS; PHENOTYPE; POSTSYNAPTIC DENSITY; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; RISK FACTOR; SLEEP DEPRIVATION; TRANSGENIC MOUSE; ANIMAL; COMPLICATION; DISEASE MODEL; GENETICS; METABOLISM; PHOSPHORYLATION; PSYCHOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; DISEASE MODELS, ANIMAL; GLIAL FIBRILLARY ACIDIC PROTEIN; GUANYLATE KINASE; LEARNING; MEMBRANE PROTEINS; MEMORY; MICE; MICE, TRANSGENIC; PHOSPHORYLATION; POST-SYNAPTIC DENSITY; RISK FACTORS; SLEEP DEPRIVATION; TAU PROTEINS;

EID: 84899939418     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.02.011     Document Type: Article

References (33)

1. Andorfer C., Kress Y., Espinoza M., De Silva R., Tucker K.L., Barde Y.A., Duff K., Davies P. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J.Neurochem. 2003, 86:582-590.
2. Bhat N.R., Thiurumangalakudi L. Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet. J.Alzheimers Dis. 2013, 36:781-789.
3. Billingsley M.L., Kincaid R.L. Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration. Biochem. J. 1997, 323:577-591.
4. Bitner R.S. Cyclic AMP response element-binding protein (CREB) phosphorylation: a mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics. Biochem. Pharmacol. 2012, 83:705-714.
5. Chu J., Li J.G., Praticò D. Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles. PLoS One 2013, 8:e70991.
6. Costa M.S., Botton P.H., Miornazza S., Ardais A.P., Moreira J.D., Souza D.O., Porciúncula L.O. Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phosphor-CREB immunocontent in the hippocampus. Neurochem. Int. 2008, 53:89-94.
7. Cricco M., Simonsick E.M., Foley D.J. The impact of insomnia on cognitive functioning in older adults. J.Am. Geriatr. Soc. 2001, 49:1185-1189.
8. Dineley K.T., Westerman M., Bui D., Bell K., Ashe K.H., Sweatt J.D. Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetyloline receptors: invitro and invivo mechanisms related to Alzheimer's disease. J.Neurosci. 2001, 21:4125-4133.
9. Dong Y., Wu X., Xu Z., Zhang Y., Xie Z. Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Aβ generation. PLoS One 2012, 7. 2012.
10. Geddes J.W., Mattson M.P. Tau hyperphosphorylation and free radicals in the PHF formation: early or late events? Commentary on Anderton BH, Brion JP, Couck AM, etal. Modulation of PHF-like tau phosphorylation in cultured neurons and transfected cells. Neurobiol. Aging 1995, 16:389-402.
11. Gerenu G., Dobarro M., Ramirez M.J., Gil-Bea F.J. Early cognitive stimulation compensates for memory and pathological changes in Tg2576 mice. Biochim. Biophys. Acta 2013, 1832:837-847.
12. Giannopoulos P.G., Joshi Y.B., Chu J., Praticò D. The 12-15-lipoxygenase is a modulator of Alzheimer's-related tau pathology invivo. Aging Cell. 2013, 12:1082-1090.
13. Greenberg S.G., Davies P., Schein J.D., Binder L.I. Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau. J.Biol. Chem. 1992, 267:564-569.
14. Joshi Y.B., Pratico D. The involvement of 5-lipoxygenase activating protein in anxiety-like behavior. J.Psychiatr. Res. 2013, 47:694-698.
15. Joshi Y.B., Chu J., Praticò D. Stress hormone leads to memory deficits and altered tau phosphorylation in a model of Alzheimer's disease. J.Alzheimers Dis. 2012, 31:167-176.
16. Kang J.E., Lim M.M., Bateman R.J., Lee J.J., Smyth L.P., Cirrito J.R., Fujiki N., Nishino S., Holtzman D.M. Amyloid-β dynamics are regulated by orexin and sleep-wake cycle. Science 2009, 326:1005-1007.
17. Li Y., Li T., Zhuang M., Wang K., Zhang J., Shi N. High-dose dibutyl phthalate improves performance of F1 generation male rats in spatial learning and increases hippocampal BDNF expression independent of p-CREB immunocontent. Environ. Toxicol. Pharmacol. 2010, 29:32-38.
18. Liao X., Zhang Y., Wang Y., Wang J. The effect of cdk-5 overexpression on tau phosphorylation and spatial memory of rat. Sci. China C Life Sci. 2004, 47:251-257.
19. Ma Q.L., Harris-White M.E., Ubeda O.J., Simmons M., Beech W., Lim G.B., Teter B., Frautschy S.A., Cole G.M. Evidence of Abeta-and transgene-dependent defects in ERK-CREB signaling in Alzheimer's models. J.Neurochem. 2007, 103:1594-1607.
20. Osorio R.S., Pirraglia E., Aguera-Ortiz L.F., During E.H., Sacks H., Ayappa I., Walsleben J., Mooney A., Hussain A., Glodzik L., Frangione B., Martínez-Martín P., de Leon M.J. Greater risk of Alzheimer' disease in older adults with insomnia. J.Am. Geriatr. Soc. 2011, 59:559-562.
21. Querfurth H.W., La Ferla F.M. Alzheimer's disease. N.Engl. J. Med. 2010, 362:329-344.
22. Roh J.H., Huang Y., Bero A.W., Kasten T., Stewart F.R., Bateman R.J., Holtzman D.M. Sleep-wake cycle and diurnal fluctuation of amyloid-β as biomarkers of brain amyloid pathology. Sci. Transl. Med. 2012, 4, 150ra 122.
23. Schweers O., Mandelkow E.M., Biernat J., Mandelkow E. Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein τ controls the invitro assembly of paired helical filaments. Proc. Natl. Acad. Sci. U.S.A 1995, 92:8463-8467.
24. Scullion G.A., Hewitt K.N., Pardon M.C. Corticotropin-releasing factor receptor 1 activation during exposure to novelty stress protects against Alzheimer's disease-like cognitive decline in AβPP/PS1 mice. J.Alzheimers Dis. 2013, 34:781-793.
25. Sultana R., Banks W.A., Butterfield D.A. Decreased levels of PSD95 and two associated proteins and increased levels of BCl2 and caspase 3 in hippocampus from subjects with amnestic mild cognitive impairment: insights into their potential roles for loss of synapses and memory, accumulation of Abeta, and neurodegeneration in a prodromal stage of Alzheimer's disease. J.Neurosci. Res. 2010, 88:469-477.
26. Tranah G.J., Blackwell T., Stone K.L., Ancoli-Israel S., Paudel M.L., Ensrud K.E., Cauley J.A., Redline S., Hillier T.A., Cummings S.R., Yaffe K. Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women. Ann. Neurol. 2011, 70:722-732.
27. Tsai L.H., Lee M.S., Cruz J. Cdk5, a therapeutic target for Alzheimer's disease?. Biochim. Biophys. Acta 2004, 1697:137-142.
28. Uboga N.V., Price J.L. Formation of diffuse and fibrillar tangles in aging and early Alzheimer's disease. Neurobiol. Aging 2000, 21:1-10.
29. Weaver C.L., Espinoza M., Kress Y., Davies P. Conformational change as one of the earliest alterations of tau in Alzheimer's disease. Neurobiol. Aging 2000, 21:719-727.
30. Wilson R.S., Arnold S.E., Schneider J.A., Kelly J.F., Tang Y., Bennett D.A. Chronic psychological distress and risk of Alzheimer's disease in old age. Neuroepidemiology 2006, 27:143-153.
31. Wyss-Coray T., Mucke L. Inflammation in neurodegenerative disease - a double-edge sword. Neuron 2002, 35:419-432.
32. Xie L., Kang H., Chen M.J., Liao Y., Thiyagarajan M., O'Donnel J., Christensen D.J., Nicholson C., Iliff J.J., Takano T., Deane R., Nedergaard M. Sleep drives metabolite clearance from adult brain. Science 2013, 342:373-377.
33. Yamamoto-Sasaki M., Ozawa H., Saito T., Rösler M., Riederer P. Impairedphosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type. Brain Res. 1999, 824:300-303.