Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia

Brain

Volumn 131, Issue 6, 2008, Pages 1609-1617

  Harper, David G ^a,b   Stopa, Edward G ^c,d   Kuo Leblanc, Victoria ^c   McKee, Ann C ^e,f   Asayama, Kentaro ^a,b   Volicer, Ladislav ^e,g   Kowall, Neil ^e,f   Satlin, Andrew ^a,b  

^a MCLEAN HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c RHODE ISLAND HOSPITAL   (United States)

^d BROWN UNIVERSITY   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Alzheimer's disease; Circadian rhythm; Neurodegeneration; Neurotensin; Vasopressin

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROTENSIN; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOPRESSIN; VASOPRESSIN RECEPTOR;

ALZHEIMER DISEASE; ARTICLE; CELL FUNCTION; CELL SUBPOPULATION; CIRCADIAN RHYTHM; CORE TEMPERATURE; FRONTOTEMPORAL DEMENTIA; HUMAN; HYPOTHALAMUS; LOCOMOTION; PRIORITY JOURNAL; SUPRACHIASMATIC NUCLEUS;

EID: 44949090437     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awn049     Document Type: Article

References (52)

1. Abe K, Kroning J, Greer MA, Critchlow V. Effects of destruction of the suprachiasmatic nuclei on the circadian rhythms in plasma corticosterone, body temperature, feeding and plasma thyrotropin. Neuroendocrinology 1979; 29: 119-31.
2. Albus H, Vansteensel MJ, Michel S, Block GD, Meijer JH. A GABAergic mechanism is necessary for coupling dissociable ventral and dorsal regional oscillators within the circadian clock. Curr Biol 2005; 15: 886-93.
3. Ancoli-Israel S, Klauber MR, Jones DW, Kripke DF, Martin J, Mason W, et al. Variations in circadian rhythms of activity, sleep, and light exposure related to dementia in nursing-home patients. Sleep 1997; 20: 18-23.
4. Bartlett MS, Kendall DG. The statistical analysis of variances- heterogeneity and the logarithmic transformation. JRSS Suppl 1946; 8: 128-38.
5. Batschelet E. Circular statistics in biology. New York: Academic Press; 1981.
6. Berson DM, Dunn FA, Takao M. Phototransduction by retinal ganglion cells that set the circadian clock. Science 2002; 295: 1070-3.
7. Bliwise DL, Hughes M, McMahon PM, Kutner N. Observed sleep/wakefulness and severity of dementia in an Alzheimer's disease special care unit. J Gerontol A Biol Sci Med Sci 1995; 50: M303-6.
8. Gillette MU, Reppert SM. The hypothalamic suprachiasmatic nuclei: circadian patterns of vasopressin secretion and neuronal activity in vitro. Brain Res Bull 1987; 19: 135-9.
9. Green DJ, Gillette R. Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice. Brain Res 1982; 245: 198-200.
10. Groos G, Hendriks J. Circadian rhythms in electrical discharge of rat suprachiasmatic neurones recorded in vitro. Neurosci Lett 1982; 34: 283-8.
11. Hansen LA, DeTeresa R, Davies P, Terry RD. Neocortical morphometry, lesion counts, and choline acetyltransferase levels in the age spectrum of Alzheimer's disease. Neurology 1988; 38: 48-54.
12. Harper DG, Stopa EG, McKee AC, Satlin A, Fish D, Volicer L. Dementia severity and Lewy bodies affect circadian rhythms in Alzheimer disease. Neurobiol Aging 2004; 25: 771-81.
13. Harper DG, Stopa EG, McKee A, Satlin A, Harlan PC, Goldstein RL, et al. Differential circadian rhythm disturbances in men with Alzheimer disease and frontotemporal degeneration. Arch Gen Psychiatry 2001; 58: 353-60.
14. Harper DG, Volicer L, Stopa EG, McKee AC, Nitta M, Satlin A. Disturbance of endogenous circadian rhythm in aging and Alzheimer disease. Am J Geriatr Psychiatry 2005; 13: 359-68.
15. Hatfield CF, Herbert J, van Someren EJ, Hodges JR, Hastings MH. Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia. Brain 2004; 127: 1061-74.
16. Hofman MA, Fliers E, Goudsmit E, Swaab DF. Morphometric analysis of the suprachiasmatic and paraventricular nuclei in the human brain: sex differences and age-dependent changes. J Anat 1988; 160: 127-43.
17. Hofman MA, Swaab DF. Alterations in circadian rhythmicity of the vasopressin-producing neurons of the human suprachiasmatic nucleus (SCN) with aging. Brain Res 1994; 651: 134-42.
18. Hofman MA, Zhou JN, Swaab DF. Suprachiasmatic nucleus of the human brain: an immunocytochemical and morphometric analysis. Anat Rec 1996; 244: 552-62.
19. King DP, Takahashi JS. Molecular genetics of circadian rhythms in mammals. Annu Rev Neurosci 2000; 23: 713-42.
20. Leak RK, Moore RY. Topographic organization of suprachiasmatic nucleus projection neurons. J Comp Neurol 2001; 433: 312-34.
21. Lehman MN, Silver R, Gladstone WR, Kahn MR, Gibson M, Brittman EL. Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain. J Neurosci 1987; 7: 1626-38.
22. LeSauter J, Silver R. Localization of a suprachiasmatic nucleus subregion regulating locomotor rhythmicity. J Neurosci 1999; 19: 5574-85.
23. Liu RY, Zhou JN, Hoogendijk WJ, van Heerikhuize J, Kamphorst W, Unmehopa UA, et al. Decreased vasopressin gene expression in the biological clock of Alzheimer disease patients with and without depression. J Neuropathol Exp Neurol 2000; 59: 314-22.
24. Mai JK, Kedziora O, Teckhaus L, Sofroniew MV. Evidence for subdivisions in the human suprachiasmatic nucleus. J Comp Neurol 1991; 305: 508-25.
25. McKee AC. Brain banking: basic science methods. Alzheimer Dis Assoc Disord 1999; 13 (Suppl 1): S39-44.
26. Mishima K, Okawa M, Satoh K, Shimizu T, Hozumi S, Hishikawa Y. Different manifestations of circadian rhythms in senile dementia of Alzheimer's type and multi-infarct dementia. Neurobiol Aging 1997; 18: 105-9.
27. Moore MR. Organization of the mammalian circadian system. In: Chadwick DJ, Ackrill K, editors. Circadian clocks and their adjustment. New York: John Wiley and Sons; 1995. pp. 88-99.
28. Moore RY. Organization and function of a central nervous system circadian oscillator: the suprachiasmatic hypothalamic nucleus. Fed Proc 1983; 42: 2783-9.
29. Moore RY. Organization of the primate circadian system. J Biol Rhythms 1993; 8 (Suppl): S3-9.
30. Moore RY, Eichler VB. Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Res 1972; 42: 201-6.
31. Peng MT, Lee LR. Regional differences of neuron loss of rat brain in old age. Gerontology 1979; 25: 205-11.
32. Prinz PN, Peskind ER, Vitaliano PP, Raskind MA, Eisdorfer C, Zemcuznikov N, et al. Changes in the sleep and waking EEGs of nondemented and demented elderly subjects. J Am Geriatr Soc 1982; 30: 86-93.
33. Probst A, Taylor KI, Tolnay M. Hippocampal sclerosis dementia: a reappraisal. Acta Neuropathol 2007; 114: 335-45.
34. Roy TS, Sharma V, Seidler FJ, Slotkin TA. Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats. Brain Res Dev Brain Res 2005; 155: 71-80.
35. Satlin A, Volicer L, Stopa EG, Harper D. Circadian locomotor activity and core-body temperature rhythms in Alzheimer's disease. Neurobiol Aging 1995; 16: 765-71.
36. Shibata S, Oomura Y, Kita H, Hattori K. Circadian rhythmic changes of neuronal activity in the suprachiasmatic nucleus of the rat hypothalamic slice. Brain Res 1982; 247: 154-8.
37. Smyth MD, Limbrick DD Jr, Ojemann JG, Zempel J, Robinson S, O'Brien DF, et al. Outcome following surgery for temporal lobe epilepsy with hippocampal involvement in preadolescent children: emphasis on mesial temporal sclerosis. J Neurosurg 2007; 106: 205-10.
38. Stephan FK, Zucker I. Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions. Proc Natl Acad Sci USA 1972; 69: 1583-6.
39. Stopa EG, Volicer L, Kuo-Leblanc V, Harper D, Lathi D, Tate B, et al. Pathologic evaluation of the human suprachiasmatic nucleus in severe dementia. J Neuropathol Exp Neurol 1999; 58: 29-39.
40. Swaab DF, Fliers E, Partiman TS. The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia. Brain Res 1985; 342: 37-44.
41. Teicher MH, Barber NI. COSIFIT: an interactive program for simultaneous multioscillator cosinor analysis of time-series data. Comput Biomed Res 1990; 23: 283-95.
42. Terry RD, Peck A, DeTeresa R, Schechter R, Horoupian DS. Some morphometric aspects of the brain in senile dementia of the Alzheimer type. Ann Neurol 1981; 10: 184-92.
43. Tominaga K, Shinohara K, Otori Y, Fukuhara C, Inouye ST. Circadian rhythms of vasopressin content in the suprachiasmatic nucleus of the rat. Neuroreport 1992; 3: 809-12.
44. Van den Pol AN. The hypothalamic suprachiasmatic nucleus of rat: intrinsic anatomy. J Comp Neurol 1980; 191: 661-702.
45. van Someren EJ, Hagebeuk EE, Lijzenga C, Scheltens P, de Rooij SE, Jonker C, et al. Circadian rest-activity rhythm disturbances in Alzheimer's disease. Biol Psychiatry 1996; 40: 259-70.
46. Vitiello MV, Borson S. Sleep disturbances in patients with Alzheimer's disease: epidemiology, pathophysiology and treatment. CNS Drugs 2001; 15: 777-96.
47. Volicer L, Harper DG, Manning BC, Goldstein R, Satlin A. Sundowning and circadian rhythms in Alzheimer's disease. Am J Psychiatry 2001; 158: 704-11.
48. Weibel E. Sampling of tissue. Stereological methods. Vol. 1. New York: Academic Press; 1989. pp. 63-100.
49. Welsh DK, Logothetis DE, Meister M, Reppert SM. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 1995; 14: 697-706.
50. Witting W, Kwa IH, Eikelenboom P, Mirmiran M, Swaab DF. Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease. Biol Psychiatry 1990; 27: 563-72.
51. Wu YH, Zhou JN, Van Heerikhuize J, Jockers R, Swaab DF. Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease. Neurobiol Aging 2007; 28: 1239-47.
52. Zhou JN, Hofman MA, Swaab DF. VIP neurons in the human SCN in relation to sex, age, and Alzheimer's disease. Neurobiol Aging 1995; 16: 571-6.