Functional CLOCK gene rs1554483 G/C polymorphism is associated with susceptibility to alzheimer's disease in the chinese population

Journal of International Medical Research

Volumn 41, Issue 2, 2013, Pages 340-346

  Chen, Qian ^a   Huang, Chang Quan ^b   Hu, Xiu Ying ^a   Li, Song Bing ^a   Zhang, Xue Mei ^a  

^a SICHUAN UNIVERSITY   (China)

^b Third Hospital of Mianyang   (China)

Author keywords

Alzheimer's disease; Apolipoprotein e (APOE); Circadian locomotor output cycles kaput (CLOCK); CLOCK gene rs1554483 G C; Polymorphism

Indexed keywords

APOLIPOPROTEIN E4; TRANSCRIPTION FACTOR CLOCK;

AGED; ALZHEIMER DISEASE; APOLIPOPROTEIN E4 GENE; ARTICLE; CASE CONTROL STUDY; CHINESE; CIRCADIAN LOCOMOTOR OUTPUT CYCLE KAPUT GENE; CONTROLLED STUDY; FEMALE; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPING TECHNIQUE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR PATHOLOGY; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 84878372382     PISSN: 03000605     EISSN: 14732300     Source Type: Journal    
DOI: 10.1177/0300060513476430     Document Type: Article

References (25)

1. Balasubramanian AB, Kawas CH, Peltz CB, et al. Alzheimer disease pathology and longitudinal cognitive performance in the oldestold with no dementia. Neurology 2012; 79: 915-921
2. Dartigues JF and Feart C. Risk factors for Alzheimer disease: aging beyond age? Neurology 2011; 77: 206-207
3. Seshadri S, Fitzpatrick AL, Ikram MA, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010; 303: 1832-1840
4. Takei N, Miyashita A, Tsukie T, et al. for the Japanese Genetic Study Consortium for Alzheimer Disease: Genetic association study on in and around the APOE in lateonset Alzheimer disease in Japanese. Genomics 2009; 93: 441-448
5. Zou F, Carrasquillo MM, Pankratz VS, et al. Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease. Neurology 2010; 74: 480-486
6. Yesavage JA, Noda A, Hernandez B, et al. for the Alzheimer's Disease Neuroimaging Initiative: Circadian clock gene polymorphisms and sleep-wake disturbance in Alzheimer disease. Am J Geriatr Psychiatry 2011; 19: 635-643
7. Späti J, Münch M, Blatter K, et al. Impact of age, sleep pressure and circadian phase on time-of-day estimates. Behav Brain Res 2009; 201: 48-52
8. Huang Y. Apolipoprotein E and Alzheimer disease. Neurology 2006; 66(SUPPL.1): S79-S85
9. Bales KR, Dodart JC, DeMattos RB, et al. Apolipoprotein E, amyloid, and Alzheimer disease. Mol Interv 2002; 2: 339, 363-375,
10. Yamaguchi H, Sugihara S, Ogawa A, et al. Alzheimer beta amyloid deposition enhanced by apoE epsilon4 gene precedes neurofibrillary pathology in the frontal association cortex of nondemented senior subjects. J Neuropathol Exp Neurol 2001; 60: 731-739
11. Cai W, Rambaud J, Teboul M, et al. Expression levels of estrogen receptor are modulated by components of the molecular clock. Mol Cell Biol 2008; 28: 784-793
12. Froy O. Metabolism and circadian rhythms - implications for obesity. Endocr Rev 2010; 31: 1-24
13. Garaulet M, Lee YC, Shen J, et al. CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids. Am J Clin Nutr 2009; 90: 1466-1475
14. Marques FZ, Campain AE, Yang YH, et al. Meta-analysis of genome-wide gene expression differences in onset and maintenance phases of genetic hypertension. Hypertension 2010; 56: 319-324
15. Feng D, Liu T, Sun Z, Bugge A, et al. A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science 2011; 331: 1315-1319
16. Harper DG, Stopa EG, McKee AC, et al. Differential circadian rhythm disturbances in men with Alzheimer disease and frontotemporal degeneration. Arch Gen Psychiatry 2001; 58: 353-360
17. Sarazin M, de Souza LC, Lehéricy S, et al. Clinical and research diagnostic criteria for Alzheimer's disease. Neuroimaging Clin N Am 2012; 22: 23-32
18. Neri AL, Ongaratto LL and Yassuda MS. Mini Mental State Examination sentence writing among community-dwelling elderly adults in Brazil: text fluency and grammar complexity. Int Psychogeriatr 2012; 24: 1732-1737
19. Casement MD, Harrington KM, Miller MW, et al. Associations between Pittsburgh Sleep Quality Index factors and health outcomes in women with posttraumatic stress disorder. Sleep Med 2012; 13: 752-758
20. Gouin JP, Connors J, Kiecolt-Glaser JK, et al. Altered expression of circadian rhythm genes among individuals with a history of depression. J Affect Disord 2010; 126: 161-166
21. Elcoroaristízabal Martin X, Fernández Martínez M, Galdos Alcelay L, et al. Progression from amnesic mild cognitive impairment to Alzheimer's disease: ESR1 and ESR2 polymorphisms and APOE gene. Dement Geriatr Cogn Disord 2011; 32: 332-341
22. Ferreira MA, Sham P, Daly MJ, et al. Ascertainment through family history of disease often decreases the power of familybased association studies. Behav Genet 2007; 37: 631-636
23. Martins IJ, Hone E, Foster JK, et al. Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Mol Psychiatry 2006; 11: 721-736
24. Ishikawa-Kobayashi E, Ushijima K, Ando H, et al. Reduced histone H3K9 acetylation of clock genes and abnormal glucose metabolism in ob/ob mice. Chronobiol Int 2012; 29: 982-993
25. Barclay JL, Husse J, Bode B, et al. Circadian desynchrony promotes metabolic disruption in a mouse model of shiftwork. PLoS One 2012; 7: e37150.