-
1
-
-
0036729484
-
Seven-Transmembrane receptors
-
Pierce, K. L., Premont, R. T., & Lefkowitz, R. J. Seven-Transmembrane receptors. Nature reviews Molecular cell biology 3, 639-650 (2002
-
(2002)
Nature Reviews Molecular Cell Biology
, vol.3
, pp. 639-650
-
-
Pierce, K.L.1
Premont, R.T.2
Lefkowitz, R.J.3
-
2
-
-
0035318509
-
Oligomerization of G-protein-coupled transmitter receptors
-
Bouvier, M. Oligomerization of G-protein-coupled transmitter receptors. Nature reviews Neuroscience 2, 274-286 (2001
-
(2001)
Nature Reviews Neuroscience
, vol.2
, pp. 274-286
-
-
Bouvier, M.1
-
3
-
-
3042663287
-
G protein-coupled receptor dimerization: Function and ligand pharmacology
-
Milligan, G. G protein-coupled receptor dimerization: function and ligand pharmacology. Mol Pharmacol 66, 1-7 (2004
-
(2004)
Mol Pharmacol
, vol.66
, pp. 1-7
-
-
Milligan, G.1
-
4
-
-
84893642127
-
G protein-coupled receptor oligomerization revisited: Functional and pharmacological perspectives
-
Ferre, S., Casado, V., Devi, L. A., Filizola, M., Jockers, R., Lohse, M. J., Milligan, G., Pin, J. P., & Guitart, X. G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives. Pharmacol Rev 66, 413-434 (2014
-
(2014)
Pharmacol Rev
, vol.66
, pp. 413-434
-
-
Ferre, S.1
Casado, V.2
Devi, L.A.3
Filizola, M.4
Jockers, R.5
Lohse, M.J.6
Milligan, G.7
Pin, J.P.8
Guitart, X.9
-
5
-
-
21344433619
-
Methods to monitor the quaternary structure of G protein-coupled receptors
-
Milligan, G., & Bouvier, M. Methods to monitor the quaternary structure of G protein-coupled receptors. FEBS J 272, 2914-2925 (2005
-
(2005)
FEBS J
, vol.272
, pp. 2914-2925
-
-
Milligan, G.1
Bouvier, M.2
-
6
-
-
33847419390
-
International union of basic and clinical pharmacology lxvii recommendations for the recognition and nomenclature of g protein-coupled receptor heteromultimers
-
Pin, J.-P., Neubig, R., Bouvier, M., Devi, L., Filizola, M., Javitch, J. A., Lohse, M. J., Milligan, G., Palczewski, K., Parmentier, M., & Spedding, M. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the Recognition and Nomenclature of G Protein-Coupled Receptor Heteromultimers. Pharmacol Rev 59, 5-13 (2007
-
(2007)
Pharmacol Rev
, vol.59
, pp. 5-13
-
-
Pin, J.-P.1
Neubig, R.2
Bouvier, M.3
Devi, L.4
Filizola, M.5
Javitch, J.A.6
Lohse, M.J.7
Milligan, G.8
Palczewski, K.9
Parmentier, M.10
Spedding, M.11
-
7
-
-
0034724192
-
Detection of beta 2-Adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET
-
Angers, S., Salahpour, A., Joly, E., Hilairet, S., Chelsky, D., Dennis, M., & Bouvier, M. Detection of beta 2-Adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc Natl Acad Sci USA 97, 3684-3689 (2000
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3684-3689
-
-
Angers, S.1
Salahpour, A.2
Joly, E.3
Hilairet, S.4
Chelsky, D.5
Dennis, M.6
Bouvier, M.7
-
8
-
-
77955982118
-
Applications of fluorescence and bioluminescence resonance energy transfer to drug discovery at G protein coupled receptors
-
Alvarez-Curto, E., Pediani, J. D., & Milligan, G. Applications of fluorescence and bioluminescence resonance energy transfer to drug discovery at G protein coupled receptors. Anal Bioanal Chem 398, 167-180 (2010
-
(2010)
Anal Bioanal Chem
, vol.398
, pp. 167-180
-
-
Alvarez-Curto, E.1
Pediani, J.D.2
Milligan, G.3
-
9
-
-
77249150932
-
Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules
-
Hern, J. A., Baig, A. H., Mashanov, G. I., Birdsall, B., Corrie, J. E. T., Lazareno, S., Molloy, J. E., & Birdsall, N. J. M. Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules. Proc Natl Acad Sci USA 107, 2693-2698 (2010
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2693-2698
-
-
Hern, J.A.1
Baig, A.H.2
Mashanov, G.I.3
Birdsall, B.4
Corrie, J.E.T.5
Lazareno, S.6
Molloy, J.E.7
Birdsall, N.J.M.8
-
10
-
-
79551711208
-
Full characterization of GPCR monomer-dimer dynamic equilibrium by single molecule imaging
-
Kasai, R. S., Suzuki, K. G., Prossnitz, E. R., Koyama-Honda, I., Nakada, C., Fujiwara, T. K., & Kusumi, A. Full characterization of GPCR monomer-dimer dynamic equilibrium by single molecule imaging. The Journal of cell biology 192, 463-480 (2011
-
(2011)
The Journal of Cell Biology
, vol.192
, pp. 463-480
-
-
Kasai, R.S.1
Suzuki, K.G.2
Prossnitz, E.R.3
Koyama-Honda, I.4
Nakada, C.5
Fujiwara, T.K.6
Kusumi, A.7
-
11
-
-
84872195772
-
Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization
-
Calebiro, D., Rieken, F., Wagner, J., Sungkaworn, T., Zabel, U., Borzi, A., Cocucci, E., Zurn, A., & Lohse, M. J. Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization. Proc Natl Acad Sci USA 110, 743-748 (2013
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 743-748
-
-
Calebiro, D.1
Rieken, F.2
Wagner, J.3
Sungkaworn, T.4
Zabel, U.5
Borzi, A.6
Cocucci, E.7
Zurn, A.8
Lohse, M.J.9
-
12
-
-
84874183639
-
Abundance distribution, mobility and oligomeric state of M2 muscarinic acetylcholine receptors in live cardiac muscle
-
Nenasheva, T. A., Neary, M., Mashanov, G. I., Birdsall, N. J. M., Breckenridge, R. A., & Molloy, J. E. Abundance, distribution, mobility and oligomeric state of M2 muscarinic acetylcholine receptors in live cardiac muscle. Journal of Molecular and Cellular Cardiology 57, 129-136 (2013
-
(2013)
Journal of Molecular and Cellular Cardiology
, vol.57
, pp. 129-136
-
-
Nenasheva, T.A.1
Neary, M.2
Mashanov, G.I.3
Birdsall, N.J.M.4
Breckenridge, R.A.5
Molloy, J.E.6
-
13
-
-
0037225952
-
A general method for the covalent labeling of fusion proteins with small molecules in vivo
-
Keppler, A., Gendreizig, S., Gronemeyer, T., Pick, H., Vogel, H., & Johnsson, K. A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nature biotechnology 21, 86-89 (2003
-
(2003)
Nature Biotechnology
, vol.21
, pp. 86-89
-
-
Keppler, A.1
Gendreizig, S.2
Gronemeyer, T.3
Pick, H.4
Vogel, H.5
Johnsson, K.6
-
14
-
-
79952032110
-
The physiology, signaling, and pharmacology of dopamine receptors
-
Beaulieu, J.-M., & Gainetdinov, R. R. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol Rev 63, 182-217 (2011
-
(2011)
Pharmacol Rev
, vol.63
, pp. 182-217
-
-
Beaulieu, J.-M.1
Gainetdinov, R.R.2
-
15
-
-
33846905526
-
Recent progress in development of dopamine receptor subtype-selective agents: Potential therapeutics for neurological and psychiatric disorders
-
Zhang, A., Neumeyer, J. L., & Baldessarini, R. J. Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders. Chem Rev 107, 274-302 (2007
-
(2007)
Chem Rev
, vol.107
, pp. 274-302
-
-
Zhang, A.1
Neumeyer, J.L.2
Baldessarini, R.J.3
-
16
-
-
0026070134
-
Dopamine in schizophrenia: A review and reconceptualization
-
Davis, K. L., Kahn, R. S., Ko, G., & Davidson, M. Dopamine in schizophrenia: a review and reconceptualization. Am J Psychiatry 148, 1474-1486 (1991
-
(1991)
Am J Psychiatry
, vol.148
, pp. 1474-1486
-
-
Davis, K.L.1
Kahn, R.S.2
Ko, G.3
Davidson, M.4
-
17
-
-
0033924207
-
Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell
-
Lee, S. P., O?Dowd, B. F., Ng, G. Y., Varghese, G., Akil, H., Mansour, A., Nguyen, T., & George, S. R. Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell. Mol Pharmacol 58, 120-128 (2000
-
(2000)
Mol Pharmacol
, vol.58
, pp. 120-128
-
-
Lee, S.P.1
O'Dowd, B.F.2
Ng, G.Y.3
Varghese, G.4
Akil, H.5
Mansour, A.6
Nguyen, T.7
George, S.R.8
-
18
-
-
0035933747
-
Dopamine D2 receptor dimer formation: Evidence from ligand binding
-
Armstrong, D., & Strange, P. G. Dopamine D2 receptor dimer formation: evidence from ligand binding. J Biol Chem 276, 22621-22629 (2001
-
(2001)
J Biol Chem
, vol.276
, pp. 22621-22629
-
-
Armstrong, D.1
Strange, P.G.2
-
19
-
-
51049112029
-
Dopamine D2 receptors form higher order oligomers at physiological expression levels
-
Guo, W., Urizar, E., Kralikova, M., Mobarec, J. C., Shi, L., Filizola, M., & Javitch, J. A. Dopamine D2 receptors form higher order oligomers at physiological expression levels. The EMBO journal 27, 2293-2304 (2008
-
(2008)
The EMBO Journal
, vol.27
, pp. 2293-2304
-
-
Guo, W.1
Urizar, E.2
Kralikova, M.3
Mobarec, J.C.4
Shi, L.5
Filizola, M.6
Javitch, J.A.7
-
20
-
-
84858607942
-
Functional homomers and heteromers of dopamine D2L and D3 receptors co-exist at the cell surface
-
Pou, C., Mannoury la Cour, C., Stoddart, L. A., Millan, M. J., & Milligan, G. Functional homomers and heteromers of dopamine D2L and D3 receptors co-exist at the cell surface. J Biol Chem 287, 8864-8878 (2012
-
(2012)
J Biol Chem
, vol.287
, pp. 8864-8878
-
-
Pou, C.1
Mannoury La Cour, C.2
Stoddart, L.A.3
Millan, M.J.4
Milligan, G.5
-
21
-
-
77955874300
-
Time-resolved FRET between GPCR ligands reveals oligomers in native tissues
-
Albizu, L., Cottet, M., Kralikova, M., Stoev, S., Seyer, R., Brabet, I., Roux, T., Bazin, H., Bourrier, E., Lamarque, L., Breton, C., Rives, M.-L., Newman, A., Javitch, J., Trinquet, E., Manning, M., Pin, J.-P., Mouillac, B., & Durroux, T. Time-resolved FRET between GPCR ligands reveals oligomers in native tissues. Nature chemical biology 6, 587-594 (2010
-
(2010)
Nature Chemical Biology
, vol.6
, pp. 587-594
-
-
Albizu, L.1
Cottet, M.2
Kralikova, M.3
Stoev, S.4
Seyer, R.5
Brabet, I.6
Roux, T.7
Bazin, H.8
Bourrier, E.9
Lamarque, L.10
Breton, C.11
Rives, M.-L.12
Newman, A.13
Javitch, J.14
Trinquet, E.15
Manning, M.16
Pin, J.-P.17
Mouillac, B.18
Durroux, T.19
-
22
-
-
72649087941
-
Heterodimerization of dopamine receptors: New insights into functional and therapeutic significance
-
Supplement 4
-
Maggio, R., Aloisi, G., Silvano, E., Rossi, M., & Millan, M. J. Heterodimerization of dopamine receptors: new insights into functional and therapeutic significance. Parkinsonism & Related Disorders 15, Supplement 4, S2-S7 (2009
-
(2009)
Parkinsonism & Related Disorders
, vol.15
, pp. S2-S7
-
-
Maggio, R.1
Aloisi, G.2
Silvano, E.3
Rossi, M.4
Millan, M.J.5
-
23
-
-
77956478769
-
Schizophrenia amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: Increased dopamine D2 receptor dimerization
-
Wang, M., Pei, L., Fletcher, P. J., Kapur, S., Seeman, P., & Liu, F. Schizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerization. Molecular brain 3, 25 (2010
-
(2010)
Molecular Brain
, vol.3
, pp. 25
-
-
Wang, M.1
Pei, L.2
Fletcher, P.J.3
Kapur, S.4
Seeman, P.5
Liu, F.6
-
24
-
-
84883036652
-
G-protein-coupled receptor (GPCR) dimers and bivalent ligands
-
Hiller, C., Kuhhorn, J., Gmeiner, P., & Class, A. G-protein-coupled receptor (GPCR) dimers and bivalent ligands. Journal of medicinal chemistry 56, 6542-6559 (2013
-
(2013)
Journal of Medicinal Chemistry
, vol.56
, pp. 6542-6559
-
-
Hiller, C.1
Kuhhorn, J.2
Gmeiner, P.3
Class, A.4
-
25
-
-
79957596498
-
Design strategies for bivalent ligands targeting GPCRs
-
Shonberg, J., Scammells, P. J., & Capuano, B. Design strategies for bivalent ligands targeting GPCRs. ChemMedChem 6, 963-974 (2011
-
(2011)
ChemMedChem
, vol.6
, pp. 963-974
-
-
Shonberg, J.1
Scammells, P.J.2
Capuano, B.3
-
26
-
-
84979787994
-
Structure-guided development of heterodimer-selective gpcr ligands
-
Hubner, H., Schellhorn, T., Gienger, M., Schaab, C., Kaindl, J., Leeb, L., Clark, T., Moller, D., & Gmeiner, P. Structure-guided development of heterodimer-selective GPCR ligands. Nat Commun 7 (2016
-
(2016)
Nat Commun
, vol.7
-
-
Hubner, H.1
Schellhorn, T.2
Gienger, M.3
Schaab, C.4
Kaindl, J.5
Leeb, L.6
Clark, T.7
Moller, D.8
Gmeiner, P.9
-
27
-
-
79960172993
-
Bivalent dopamine D2 receptor ligands: Synthesis and binding properties
-
Kuhhorn, J., Hubner, H., & Gmeiner, P. Bivalent dopamine D2 receptor ligands: synthesis and binding properties. Journal of medicinal chemistry 54, 4896-4903 (2011
-
(2011)
Journal of Medicinal Chemistry
, vol.54
, pp. 4896-4903
-
-
Kuhhorn, J.1
Hubner, H.2
Gmeiner, P.3
-
28
-
-
84896403854
-
Cryogenic colocalization microscopy for nanometer-distance measurements
-
Weisenburger, S., Jing, B., Hanni, D., Reymond, L., Schuler, B., Renn, A., & Sandoghdar, V. Cryogenic colocalization microscopy for nanometer-distance measurements. Chemphyschem: a European journal of chemical physics and physical chemistry 15, 763-770 (2014
-
(2014)
Chemphyschem: A European Journal of Chemical Physics and Physical Chemistry
, vol.15
, pp. 763-770
-
-
Weisenburger, S.1
Jing, B.2
Hanni, D.3
Reymond, L.4
Schuler, B.5
Renn, A.6
Sandoghdar, V.7
-
29
-
-
84896876399
-
Cryogenic localization of single molecules with angstrom precision. Proc. SPIE 8815
-
88150D-88150D-9
-
Weisenburger, S., Jing, B., Renn, A., & Sandoghdar, V. Cryogenic localization of single molecules with angstrom precision. Proc. SPIE 8815, Nanoimaging and Nanospectroscopy 8815, 88150D-88150D-9 (2013
-
(2013)
Nanoimaging and Nanospectroscopy
, vol.8815
-
-
Weisenburger, S.1
Jing, B.2
Renn, A.3
Sandoghdar, V.4
-
30
-
-
0023000723
-
Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain
-
Boyson, S. J., McGonigle, P., & Molinoff, P. B. Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain. The Journal of neuroscience: the official journal of the Society for Neuroscience 6, 3177-3188 (1986
-
(1986)
The Journal of Neuroscience: The Official Journal of the Society for Neuroscience
, vol.6
, pp. 3177-3188
-
-
Boyson, S.J.1
McGonigle, P.2
Molinoff, P.B.3
-
31
-
-
0000282961
-
Brownian motion in biological membranes
-
Saffman, P. G., & Delbruck, M. Brownian motion in biological membranes. Proc Natl Acad Sci USA 72, 3111-3113 (1975
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 3111-3113
-
-
Saffman, P.G.1
Delbruck, M.2
-
32
-
-
76049117057
-
Fast background-free, 3D super-resolution optical fluctuation imaging (SOFI
-
Dertinger, T., Colyer, R., Iyer, G., Weiss, S., & Enderlein, J. Fast, background-free, 3D super-resolution optical fluctuation imaging (SOFI). Proc Natl Acad Sci USA 106, 22287-22292 (2009
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 22287-22292
-
-
Dertinger, T.1
Colyer, R.2
Iyer, G.3
Weiss, S.4
Enderlein, J.5
-
33
-
-
78650157317
-
Superresolution optical fluctuation imaging with organic dyes
-
Dertinger, T., Heilemann, M., Vogel, R., Sauer, M., & Weiss, S. Superresolution Optical Fluctuation Imaging with Organic Dyes. Angew Chem Int Edit 49, 9441-9443 (2010
-
(2010)
Angew Chem Int Edit
, vol.49
, pp. 9441-9443
-
-
Dertinger, T.1
Heilemann, M.2
Vogel, R.3
Sauer, M.4
Weiss, S.5
-
34
-
-
84856499330
-
Bayesian localization microscopy reveals nanoscale podosome dynamics
-
Cox, S., Rosten, E., Monypenny, J., Jovanovic-Talisman, T., Burnette, D. T., Lippincott-Schwartz, J., Jones, G. E., & Heintzmann, R. Bayesian localization microscopy reveals nanoscale podosome dynamics. Nat Methods 9, 195-200 (2012
-
(2012)
Nat Methods
, vol.9
, pp. 195-200
-
-
Cox, S.1
Rosten, E.2
Monypenny, J.3
Jovanovic-Talisman, T.4
Burnette, D.T.5
Lippincott-Schwartz, J.6
Jones, G.E.7
Heintzmann, R.8
-
35
-
-
0037099395
-
A stepwise huisgen cycloaddition process: Copper(i)-catalyzed regioselective ligation of azides and terminal alkynes
-
2596- +
-
Rostovtsev, V. V., Green, L. G., Fokin, V. V., & Sharpless, K. B. A stepwise Huisgen cycloaddition process: Copper(I)-catalyzed regioselective ligation of azides and terminal alkynes. Angew Chem Int Edit 41, 2596- + (2002
-
(2002)
Angew Chem Int Edit
, vol.41
-
-
Rostovtsev, V.V.1
Green, L.G.2
Fokin, V.V.3
Sharpless, K.B.4
-
36
-
-
79952454207
-
Recent advances in the search for D3-And D4-selective drugs: Probes, models and candidates
-
Lober, S., Hubner, H., Tschammer, N., & Gmeiner, P. Recent advances in the search for D3-And D4-selective drugs: probes, models and candidates. Trends Pharmacol Sci 32, 148-157 (2011
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 148-157
-
-
Lober, S.1
Hubner, H.2
Tschammer, N.3
Gmeiner, P.4
-
37
-
-
0012409009
-
3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: An antagonist with high affinity and selectivity for the human dopamine D4 receptor
-
Kulagowski, J. J., Broughton, H. B., Curtis, N. R., Mawer, I. M., Ridgill, M. P., Baker, R., Emms, F., Freedman, S. B., Marwood, R., Patel, S., Patel, S., Ragan, C. I., & Leeson, P. D. 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. Journal of medicinal chemistry 39, 1941-1942 (1996
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, pp. 1941-1942
-
-
Kulagowski, J.J.1
Broughton, H.B.2
Curtis, N.R.3
Mawer, I.M.4
Ridgill, M.P.5
Baker, R.6
Emms, F.7
Freedman, S.B.8
Marwood, R.9
Patel, S.10
Patel, S.11
Ragan, C.I.12
Leeson, P.D.13
-
38
-
-
0033584150
-
22-Dicyanovinyl as a nonaromatic aryl bioisostere: Syn thesis binding experiments and SAR studies of highly selective dopamine D4 receptor ligands
-
Haubmann, C., Hubner, H., & Gmeiner, P. 2,2-Dicyanovinyl as a nonaromatic aryl bioisostere: synthesis, binding experiments and SAR studies of highly selective dopamine D4 receptor ligands. Bioorg Med Chem Lett 9, 1969-1972 (1999
-
(1999)
Bioorg Med Chem Lett
, vol.9
, pp. 1969-1972
-
-
Haubmann, C.1
Hubner, H.2
Gmeiner, P.3
-
39
-
-
61449236177
-
Analysis of receptor oligomerization by FRAP microscopy
-
Dorsch, S., Klotz, K.-N., Engelhardt, S., Lohse, M. J., & Bunemann, M. Analysis of receptor oligomerization by FRAP microscopy. Nat Meth 6, 225-230 (2009
-
(2009)
Nat Meth
, vol.6
, pp. 225-230
-
-
Dorsch, S.1
Klotz, K.-N.2
Engelhardt, S.3
Lohse, M.J.4
Bunemann, M.5
-
40
-
-
84930679031
-
Distinct agonist regulation of muscarinic acetylcholine m2-m3 heteromers and their corresponding homomers
-
Aslanoglou, D., Alvarez-Curto, E., Marsango, S., & Milligan, G. Distinct Agonist Regulation of Muscarinic Acetylcholine M2-M3 Heteromers and Their Corresponding Homomers. J Biol Chem 290, 14785-14796 (2015
-
(2015)
J Biol Chem
, vol.290
, pp. 14785-14796
-
-
Aslanoglou, D.1
Alvarez-Curto, E.2
Marsango, S.3
Milligan, G.4
-
41
-
-
84925871557
-
Dual agonist occupancy of at1-r-α 2c-Ar heterodimers results in atypical gs-pka signaling
-
Bellot, M., Galandrin, S., Boularan, C., Matthies, H. J., Despas, F., Denis, C., Javitch, J., Mazeres, S., Sanni, S. J., Pons, V., Seguelas, M.-H., Hansen, J. L., Pathak, A., Galli, A., Senard, J.-M., & Gales, C. Dual agonist occupancy of AT1-R-α 2C-AR heterodimers results in atypical Gs-PKA signaling. Nature chemical biology 11, 271-279 (2015
-
(2015)
Nature Chemical Biology
, vol.11
, pp. 271-279
-
-
Bellot, M.1
Galandrin, S.2
Boularan, C.3
Matthies, H.J.4
Despas, F.5
Denis, C.6
Javitch, J.7
Mazeres, S.8
Sanni, S.J.9
Pons, V.10
Seguelas, M.-H.11
Hansen, J.L.12
Pathak, A.13
Galli, A.14
Senard, J.-M.15
Gales, C.16
-
42
-
-
60049098657
-
Beitrage zur theorie des mikroskops und der mikroskopischen wahrnehmung
-
Abbe, E. Beitrage zur Theorie des Mikroskops und der mikroskopischen Wahrnehmung. Archiv f mikrosk Anatomie 9, 413-418 (1873
-
(1873)
Archiv F Mikrosk Anatomie
, vol.9
, pp. 413-418
-
-
Abbe, E.1
-
43
-
-
58149236663
-
Microscopy and its focal switch
-
Hell, S. W. Microscopy and its focal switch. Nat Meth 6, 24-32 (2009
-
(2009)
Nat Meth
, vol.6
, pp. 24-32
-
-
Hell, S.W.1
-
44
-
-
67650762824
-
Super-resolution fluorescence microscopy
-
Huang, B., Bates, M., & Zhuang, X. W. Super-Resolution Fluorescence Microscopy. Annu Rev Biochem 78, 993-1016 (2009
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 993-1016
-
-
Huang, B.1
Bates, M.2
Zhuang, X.W.3
-
45
-
-
84928767355
-
Light microscopy: An ongoing contemporary revolution
-
Weisenburger, S., & Sandoghdar, V. Light microscopy: an ongoing contemporary revolution. Contemp Phys 56, 123-143 (2015
-
(2015)
Contemp Phys
, vol.56
, pp. 123-143
-
-
Weisenburger, S.1
Sandoghdar, V.2
-
46
-
-
0033548657
-
Illuminating single molecules in condensed matter
-
Moerner, W. E., & Orrit, M. Illuminating single molecules in condensed matter. Science 283, 1670-1676 (1999
-
(1999)
Science
, vol.283
, pp. 1670-1676
-
-
Moerner, W.E.1
Orrit, M.2
-
47
-
-
4444221565
-
Ucsf chimera-A visualization system for exploratory research and analysis
-
Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C., & Ferrin, T. E. UCSF Chimera-A visualization system for exploratory research and analysis. J Comput Chem 25, 1605-1612 (2004
-
(2004)
J Comput Chem
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
48
-
-
0026695537
-
Structural subtypes of the dopamine D2 receptor are functionally distinct: Expression of the cloned D2A and D2B subtypes in a heterologous cell line
-
Hayes, G., Biden, T. J., Selbie, L. A., & Shine, J. Structural subtypes of the dopamine D2 receptor are functionally distinct: expression of the cloned D2A and D2B subtypes in a heterologous cell line. Mol Endocrinol 6, 920-926 (1992
-
(1992)
Mol Endocrinol
, vol.6
, pp. 920-926
-
-
Hayes, G.1
Biden, T.J.2
Selbie, L.A.3
Shine, J.4
-
49
-
-
0025179967
-
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics
-
Sokoloff, P., Giros, B., Martres, M. P., Bouthenet, M. L., & Schwartz, J. C. Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. Nature 347, 146-151 (1990
-
(1990)
Nature
, vol.347
, pp. 146-151
-
-
Sokoloff, P.1
Giros, B.2
Martres, M.P.3
Bouthenet, M.L.4
Schwartz, J.C.5
-
50
-
-
79953775165
-
Highly potent 5-Aminotetrahydropyrazolopyridines: Enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions
-
Tschammer, N., Elsner, J., Goetz, A., Ehrlich, K., Schuster, S., Ruberg, M., Kuhhorn, J., Thompson, D., Whistler, J., Hubner, H., & Gmeiner, P. Highly potent 5-Aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions. Journal of medicinal chemistry 54, 2477-2491 (2011
-
(2011)
Journal of Medicinal Chemistry
, vol.54
, pp. 2477-2491
-
-
Tschammer, N.1
Elsner, J.2
Goetz, A.3
Ehrlich, K.4
Schuster, S.5
Ruberg, M.6
Kuhhorn, J.7
Thompson, D.8
Whistler, J.9
Hubner, H.10
Gmeiner, P.11
-
51
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L., & Randall, R. J. Protein measurement with the Folin phenol reagent. J Biol Chem 193, 265-275 (1951
-
(1951)
J Biol Chem
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
52
-
-
0038248584
-
Conjugated enynes as nonaromatic catechol bioisosteres: Syn thesis, binding experiments, and computational studies of novel dopamine receptor agonists recognizing preferentially the d3 subtype
-
Hubner, H., Haubmann, C., Utz, W., & Gmeiner, P. Conjugated Enynes as Nonaromatic Catechol Bioisosteres: Synthesis, Binding Experiments, and Computational Studies of Novel Dopamine Receptor Agonists Recognizing Preferentially the D3 Subtype. Journal of medicinal chemistry 43, 756-762 (2000
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, pp. 756-762
-
-
Hubner, H.1
Haubmann, C.2
Utz, W.3
Gmeiner, P.4
-
53
-
-
0015861774
-
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
-
Cheng, Y., & Prusoff, W. H. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol 22, 3099-3108 (1973
-
(1973)
Biochem Pharmacol
, vol.22
, pp. 3099-3108
-
-
Cheng, Y.1
Prusoff, W.H.2
-
54
-
-
57749114748
-
The third intracellular loop stabilizes the inactive state of the neuropeptide Y1 receptor
-
Chee, M. J. S., Morl, K., Lindner, D., Merten, N., Zamponi, G. W., Light, P. E., Beck-Sickinger, A. G., & Colmers, W. F. The third intracellular loop stabilizes the inactive state of the neuropeptide Y1 receptor. J Biol Chem 283, 33337-33346 (2008
-
(2008)
J Biol Chem
, vol.283
, pp. 33337-33346
-
-
Chee, M.J.S.1
Morl, K.2
Lindner, D.3
Merten, N.4
Zamponi, G.W.5
Light, P.E.6
Beck-Sickinger, A.G.7
Colmers, W.F.8
-
55
-
-
84889564886
-
Activation and allosteric modulation of a muscarinic acetylcholine receptor
-
Kruse, A. C., Ring, A. M., Manglik, A., Hu, J., Hu, K., Eitel, K., Hubner, H., Pardon, E., Valant, C., Sexton, P. M., Christopoulos, A., Felder, C. C., Gmeiner, P., Steyaert, J., Weis, W. I., Garcia, K. C., Wess, J., & Kobilka, B. K. Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature 504, 101-106 (2013
-
(2013)
Nature
, vol.504
, pp. 101-106
-
-
Kruse, A.C.1
Ring, A.M.2
Manglik, A.3
Hu, J.4
Hu, K.5
Eitel, K.6
Hubner, H.7
Pardon, E.8
Valant, C.9
Sexton, P.M.10
Christopoulos, A.11
Felder, C.C.12
Gmeiner, P.13
Steyaert, J.14
Weis, W.I.15
Garcia, K.C.16
Wess, J.17
Kobilka, B.K.18
-
56
-
-
0037330690
-
Visualizing single molecules inside living cells using total internal reflection fluorescence microscopy
-
Mashanov, G. I., Tacon, D., Knight, A. E., Peckham, M., & Molloy, J. E. Visualizing single molecules inside living cells using total internal reflection fluorescence microscopy. Methods 29, 142-152 (2003
-
(2003)
Methods
, vol.29
, pp. 142-152
-
-
Mashanov, G.I.1
Tacon, D.2
Knight, A.E.3
Peckham, M.4
Molloy, J.E.5
-
57
-
-
77950468071
-
Direct observation of individual KCNQ1 potassium channels reveals their distinctive diffusive behavior
-
Mashanov, G. I., Nobles, M., Harmer, S. C., Molloy, J. E., & Tinker, A. Direct observation of individual KCNQ1 potassium channels reveals their distinctive diffusive behavior. J Biol Chem 285, 3664-3675 (2010
-
(2010)
J Biol Chem
, vol.285
, pp. 3664-3675
-
-
Mashanov, G.I.1
Nobles, M.2
Harmer, S.C.3
Molloy, J.E.4
Tinker, A.5
-
58
-
-
33947697260
-
Automatic detection of single fluorophores in live cells
-
Mashanov, G. I., & Molloy, J. E. Automatic detection of single fluorophores in live cells. Biophys J 92, 2199-2211 (2007
-
(2007)
Biophys J
, vol.92
, pp. 2199-2211
-
-
Mashanov, G.I.1
Molloy, J.E.2
-
59
-
-
84873393688
-
ImageJ plug-in for Bayesian analysis of blinking and bleaching
-
Rosten, E., Jones, G. E., & Cox, S. ImageJ plug-in for Bayesian analysis of blinking and bleaching. Nat Meth 10, 97-98 (2013
-
(2013)
Nat Meth
, vol.10
, pp. 97-98
-
-
Rosten, E.1
Jones, G.E.2
Cox, S.3
-
61
-
-
84879596846
-
Functionally selective dopamine D2/D3 receptor agonists comprising an enyne moiety
-
Hiller, C., Kling, R. C., Heinemann, F. W., Meyer, K., Hubner, H., & Gmeiner, P. Functionally selective dopamine D2/D3 receptor agonists comprising an enyne moiety. Journal of medicinal chemistry 56, 5130-5141 (2013
-
(2013)
Journal of Medicinal Chemistry
, vol.56
, pp. 5130-5141
-
-
Hiller, C.1
Kling, R.C.2
Heinemann, F.W.3
Meyer, K.4
Hubner, H.5
Gmeiner, P.6
-
62
-
-
0031473847
-
Swiss-model and the swiss-pdbviewer: An environment for comparative protein modeling
-
Guex, N., & Peitsch, M. C. SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling. Electrophoresis 18, 2714-2723 (1997
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
-
63
-
-
84876197291
-
Crystal structure of oligomeric β 1-Adrenergic G protein-coupled receptors in ligandfree basal state
-
Huang, J., Chen, S., Zhang, J. J., & Huang, X.-Y. Crystal structure of oligomeric β 1-Adrenergic G protein-coupled receptors in ligandfree basal state. Nat Struct Mol Biol 20, 419-425 (2013
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 419-425
-
-
Huang, J.1
Chen, S.2
Zhang, J.J.3
Huang, X.-Y.4
|