Conjugated enynes as nonaromatic catechol bioisosteres: Synthesis, binding experiments, and computational studies of novel dopamine receptor agonists recognizing preferentially the D3 subtype

Journal of Medicinal Chemistry

Volumn 43, Issue 4, 2000, Pages 756-762

  Hübner, Harald ^a   Haubmann, Christian ^a   Utz, Wolfgang ^a   Gmeiner, Peter ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

(4 ETHYNYLCYCLOHEX 3 ENYL)DIPROPYLAMINE; 4 AMINOBUTYRIC ACID; DIPROPYL (4 TRIMETHYLSILYLETHYNYLCYCLOHEX 3 ENYL)AMINE; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR STIMULATING AGENT; DOPAMINE 4 RECEPTOR; GABOXADOL; PRAMIPEXOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SPECIFICITY; DRUG SYNTHESIS; NONHUMAN; RECEPTOR AFFINITY;

ALKYNES; ANIMALS; CATTLE; CHO CELLS; CRICETINAE; CYCLOHEXYLAMINES; DOPAMINE AGONISTS; HUMANS; MODELS, MOLECULAR; PROPYLAMINES; RECEPTORS, DOPAMINE D2; STRUCTURE-ACTIVITY RELATIONSHIP; TRIMETHYLSILYL COMPOUNDS;

EID: 0038248584     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991098z     Document Type: Article

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