Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis

Journal of Clinical Investigation

Volumn 126, Issue 8, 2016, Pages 3063-3079

  Xie, Ting ^a   Liang, Jiurong ^a   Liu, Ningshan ^a   Huan, Caijuan ^a,b   Zhang, Yanli ^a,c   Liu, Weijia ^d,e   Kumar, Maya ^f   Xiao, Rui ^g   D'Armiento, Jeanine ^g   Metzger, Daniel ^h   Chambon, Pierre ^h   Papaioannou, Virginia E ^g   Stripp, Barry R ^a   Jiang, Dianhua ^a   Noble, Paul W ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b ZHEJIANG UNIVERSITY   (China)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e GUIZHOU PROVINCIAL PEOPLE'S HOSPITAL   (China)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g Department of Medicine   (United States)

^h INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CHONDROITIN SULFATE PROTEOGLYCAN 4; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGEN TYPE 3; COLLAGEN TYPE 4; DESMIN; FOXD PROTEIN; FOXJ PROTEIN; HYALURONAN SYNTHASE 2; HYALURONIC ACID; NEUTROPHIL COLLAGENASE; NG 4 PROTEIN; PLATELET DERIVED GROWTH FACTOR; PROTEIN; PROTEOCHONDROITIN SULFATE; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD7 PROTEIN; SMOOTH MUSCLE ACTIN; STROMELYSIN 2; STROMELYSIN 3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX11; TRANSCRIPTION FACTOR T BOX GENE 4; TRANSCRIPTION FACTOR TBX5; UNCLASSIFIED DRUG; VIMENTIN; GLUCURONOSYLTRANSFERASE; HAS2 PROTEIN, MOUSE; T BOX TRANSCRIPTION FACTOR; TBX4 PROTEIN, HUMAN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BIOACCUMULATION; CELL INVASION; CELL LINEAGE; CONTROLLED STUDY; FEMALE; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; LUNG FIBROSIS; LUNG INJURY; MALE; MESENCHYMAL STEM CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CHEMISTRY; CONFOCAL MICROSCOPY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; LUNG; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENE;

ANIMALS; BLEOMYCIN; CELL LINEAGE; CELL PROLIFERATION; ENDOTHELIAL CELLS; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; GLUCURONOSYLTRANSFERASE; HUMANS; LUNG; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MYOFIBROBLASTS; PULMONARY FIBROSIS; SIGNAL TRANSDUCTION; STEM CELLS; T-BOX DOMAIN PROTEINS; TRANSGENES;

EID: 84987791194     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI85328     Document Type: Article

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