메뉴 건너뛰기




Volumn 514, Issue 7524, 2014, Pages 585-590

Mesenchymal-endothelial transition contributes to cardiac neovascularization

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 84908403146     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13839     Document Type: Article
Times cited : (301)

References (40)
  • 1
    • 84887360805 scopus 로고    scopus 로고
    • Systematic characterization of myocardial inflammation, repair, and remodeling in a mouse model of reperfused myocardial infarction
    • Christia, P. et al. Systematic characterization of myocardial inflammation, repair, and remodeling in a mouse model of reperfused myocardial infarction. J. Histochem. Cytochem. 61, 555-570 (2013).
    • (2013) J. Histochem. Cytochem. , vol.61 , pp. 555-570
    • Christia, P.1
  • 2
    • 0034162004 scopus 로고    scopus 로고
    • Cardiac remodeling-concepts and clinical implications: A consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling
    • Cohn, J. N., Ferrari, R. & Sharpe, N. Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. J. Am. Coll. Cardiol. 35, 569-582 (2000).
    • (2000) J. Am. Coll. Cardiol. , vol.35 , pp. 569-582
    • Cohn, J.N.1    Ferrari, R.2    Sharpe, N.3
  • 3
    • 0035044085 scopus 로고    scopus 로고
    • Neovascularization of ischemic myocardium by human bonemarrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
    • Kocher, A. A. et al. Neovascularization of ischemic myocardium by human bonemarrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nature Med. 7, 430-436 (2001).
    • (2001) Nature Med. , vol.7 , pp. 430-436
    • Kocher, A.A.1
  • 4
    • 73349122017 scopus 로고    scopus 로고
    • Cardiac fibroblast: The renaissance cell
    • Souders, C. A., Bowers, S. L. & Baudino, T. A. Cardiac fibroblast: the renaissance cell. Circ. Res. 105, 1164-1176 (2009).
    • (2009) Circ. Res. , vol.105 , pp. 1164-1176
    • Souders, C.A.1    Bowers, S.L.2    Baudino, T.A.3
  • 5
    • 34547676391 scopus 로고    scopus 로고
    • Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
    • Zeisberg, E. M. et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nature Med. 13, 952-961 (2007).
    • (2007) Nature Med. , vol.13 , pp. 952-961
    • Zeisberg, E.M.1
  • 6
    • 0037350079 scopus 로고    scopus 로고
    • Cardiacmyofibroblasts: A novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR
    • Chintalgattu, V., Nair, D. M. & Katwa, L. C. Cardiacmyofibroblasts: a novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR. J. Mol. Cell. Cardiol. 35, 277-286 (2003).
    • (2003) J. Mol. Cell. Cardiol. , vol.35 , pp. 277-286
    • Chintalgattu, V.1    Nair, D.M.2    Katwa, L.C.3
  • 7
    • 0035938195 scopus 로고    scopus 로고
    • Release of pro- and anti-angiogenic factors by human cardiac fibroblasts: Effects on DNA synthesis and protection under hypoxia in human endothelial cells
    • Zhao, L. & Eghbali-Webb, M. Release of pro- and anti-angiogenic factors by human cardiac fibroblasts: effects on DNA synthesis and protection under hypoxia in human endothelial cells. Biochim. Biophys. Acta 1538, 273-282 (2001).
    • (2001) Biochim. Biophys. Acta , vol.1538 , pp. 273-282
    • Zhao, L.1    Eghbali-Webb, M.2
  • 8
    • 84863629484 scopus 로고    scopus 로고
    • In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
    • Qian, L. et al. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 485, 593-598 (2012).
    • (2012) Nature , vol.485 , pp. 593-598
    • Qian, L.1
  • 9
    • 84863626782 scopus 로고    scopus 로고
    • Heart repair by reprogramming non-myocytes with cardiac transcription factors
    • Song, K. et al. Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature 485, 599-604 (2012).
    • (2012) Nature , vol.485 , pp. 599-604
    • Song, K.1
  • 10
    • 84857192566 scopus 로고    scopus 로고
    • Wnt1/β-catenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
    • Duan, J. et al. Wnt1/β-catenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. EMBO J. 31, 429-442 (2012).
    • (2012) EMBO J. , vol.31 , pp. 429-442
    • Duan, J.1
  • 11
    • 0036097913 scopus 로고    scopus 로고
    • Liganddependent genetic recombination in fibroblasts: A potentially powerful technique for investigating gene function in fibrosis
    • Zheng, B., Zhang, Z., Black, C. M., de Crombrugghe, B. & Denton, C. Liganddependent genetic recombination in fibroblasts: a potentially powerful technique for investigating gene function in fibrosis. Am. J. Pathol. 160, 1609-1617 (2002).
    • (2002) Am. J. Pathol. , vol.160 , pp. 1609-1617
    • Zheng, B.1    Zhang, Z.2    Black, C.M.3    De Crombrugghe, B.4    Denton, C.5
  • 12
    • 84891815577 scopus 로고    scopus 로고
    • CCN2 expression by fibroblasts is not required for cutaneous tissue repair
    • Liu, S., Thompson, K. & Leask, A. CCN2 expression by fibroblasts is not required for cutaneous tissue repair. Wound Repair Regen. 22, 119-124 (2014).
    • (2014) Wound Repair Regen. , vol.22 , pp. 119-124
    • Liu, S.1    Thompson, K.2    Leask, A.3
  • 13
    • 73949140059 scopus 로고    scopus 로고
    • A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
    • Madisen, L. et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nature Neurosci. 13, 133-140 (2010).
    • (2010) Nature Neurosci. , vol.13 , pp. 133-140
    • Madisen, L.1
  • 14
    • 1842632667 scopus 로고    scopus 로고
    • Endothelial cell-cell junctions: Happy together
    • Dejana, E. Endothelial cell-cell junctions: happy together. Nature Rev. Mol. Cell Biol. 5, 261-270 (2004).
    • (2004) Nature Rev. Mol. Cell Biol. , vol.5 , pp. 261-270
    • Dejana, E.1
  • 15
    • 84858006645 scopus 로고    scopus 로고
    • Visualization and quantification of cardiac mitochondrial protein clusters with STED microscopy
    • Singh, H. et al. Visualization and quantification of cardiac mitochondrial protein clusters with STED microscopy. Mitochondrion 12, 230-236 (2012).
    • (2012) Mitochondrion , vol.12 , pp. 230-236
    • Singh, H.1
  • 16
    • 54049101650 scopus 로고    scopus 로고
    • Direct labeling and visualization of blood vessels with lipophilic carbocyanine dye DiI
    • Li, Y. et al. Direct labeling and visualization of blood vessels with lipophilic carbocyanine dye DiI. Nature Protocols 3, 1703-1708 (2008).
    • (2008) Nature Protocols , vol.3 , pp. 1703-1708
    • Li, Y.1
  • 17
    • 4143052506 scopus 로고    scopus 로고
    • Endothelial progenitor cells: Characterization and role in vascular biology
    • Urbich, C. & Dimmeler, S. Endothelial progenitor cells: characterization and role in vascular biology. Circ. Res. 95, 343-353 (2004).
    • (2004) Circ. Res. , vol.95 , pp. 343-353
    • Urbich, C.1    Dimmeler, S.2
  • 20
    • 79955498411 scopus 로고    scopus 로고
    • Adult mouse epicardium modulates myocardial injury by secreting paracrine factors
    • Zhou, B. et al. Adult mouse epicardium modulates myocardial injury by secreting paracrine factors. J. Clin. Invest. 121, 1894-1904 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 1894-1904
    • Zhou, B.1
  • 21
    • 84861394103 scopus 로고    scopus 로고
    • The bHLH transcription factor Tcf21 is required for lineagespecific EMT of cardiac fibroblast progenitors
    • Acharya, A. et al. The bHLH transcription factor Tcf21 is required for lineagespecific EMT of cardiac fibroblast progenitors. Development 139, 2139-2149 (2012).
    • (2012) Development , vol.139 , pp. 2139-2149
    • Acharya, A.1
  • 22
    • 57149113728 scopus 로고    scopus 로고
    • Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
    • Lin, S. L., Kisseleva, T., Brenner, D. A. & Duffield, J. S. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am. J. Pathol. 173, 1617-1627 (2008).
    • (2008) Am. J. Pathol. , vol.173 , pp. 1617-1627
    • Lin, S.L.1    Kisseleva, T.2    Brenner, D.A.3    Duffield, J.S.4
  • 23
    • 2542445544 scopus 로고    scopus 로고
    • Molecular and cell-based therapies for protection, rescue, and repair of ischemic myocardium: Reasons for cautious optimism
    • Melo, L. G. et al. Molecular and cell-based therapies for protection, rescue, and repair of ischemic myocardium: reasons for cautious optimism. Circulation 109, 2386-2393 (2004).
    • (2004) Circulation , vol.109 , pp. 2386-2393
    • Melo, L.G.1
  • 24
    • 0037067656 scopus 로고    scopus 로고
    • P53: Good cop/bad cop
    • Sharpless, N. E. & DePinho, R. A. p53: good cop/bad cop. Cell 110, 9-12 (2002).
    • (2002) Cell , vol.110 , pp. 9-12
    • Sharpless, N.E.1    Depinho, R.A.2
  • 25
    • 69349100179 scopus 로고    scopus 로고
    • Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
    • Hong, H. et al. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460, 1132-1135 (2009).
    • (2009) Nature , vol.460 , pp. 1132-1135
    • Hong, H.1
  • 26
    • 79952283482 scopus 로고    scopus 로고
    • P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • Chang, C. J. et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nature Cell Biol. 13, 317-323 (2011).
    • (2011) Nature Cell Biol. , vol.13 , pp. 317-323
    • Chang, C.J.1
  • 27
    • 0032933179 scopus 로고    scopus 로고
    • Effect of serum starvation on expression and phosphorylation of PKC-alpha and p53 in V79 cells: Implications for cell death
    • Hasan, N. M., Adams, G. E. & Joiner, M. C. Effect of serum starvation on expression and phosphorylation of PKC-alpha and p53 in V79 cells: implications for cell death. Int. J. Cancer 80, 400-405 (1999).
    • (1999) Int. J. Cancer , vol.80 , pp. 400-405
    • Hasan, N.M.1    Adams, G.E.2    Joiner, M.C.3
  • 28
    • 84870386893 scopus 로고    scopus 로고
    • Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin
    • Shi, Y. et al. Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin. BMC Cancer 12, 571 (2012).
    • (2012) BMC Cancer , vol.12 , pp. 571
    • Shi, Y.1
  • 29
    • 0033543728 scopus 로고    scopus 로고
    • A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
    • Komarov, P. G. et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285, 1733-1737 (1999).
    • (1999) Science , vol.285 , pp. 1733-1737
    • Komarov, P.G.1
  • 30
    • 0034656212 scopus 로고    scopus 로고
    • Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
    • Marino, S., Vooijs, M., van Der Gulden, H., Jonkers, J. & Berns, A. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev. 14, 994-1004 (2000).
    • (2000) Genes Dev. , vol.14 , pp. 994-1004
    • Marino, S.1    Vooijs, M.2    Van Der-Gulden, H.3    Jonkers, J.4    Berns, A.5
  • 31
    • 11144315535 scopus 로고    scopus 로고
    • Smallmolecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
    • Issaeva, N. et al. Smallmolecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. Nature Med. 10, 1321-1328 (2004).
    • (2004) Nature Med. , vol.10 , pp. 1321-1328
    • Issaeva, N.1
  • 32
    • 1842559902 scopus 로고    scopus 로고
    • Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation
    • Bruhl, T. et al. Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation. Circ. Res. 94, 743-751 (2004).
    • (2004) Circ. Res. , vol.94 , pp. 743-751
    • Bruhl, T.1
  • 34
    • 33745843261 scopus 로고    scopus 로고
    • + cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines
    • + cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J. Clin. Invest. 116, 1865-1877 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 1865-1877
    • Fazel, S.1
  • 35
    • 65649113763 scopus 로고    scopus 로고
    • Histone H2AX is integral to hypoxia-driven neovascularization
    • Economopoulou, M. et al. Histone H2AX is integral to hypoxia-driven neovascularization. Nature Med. 15, 553-558 (2009).
    • (2009) Nature Med. , vol.15 , pp. 553-558
    • Economopoulou, M.1
  • 36
    • 0032728077 scopus 로고    scopus 로고
    • Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or apHshift and is independent of p53
    • Bishopric, N. H. et al. Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or apHshift and is independent of p53. J. Clin. Invest. 104,239-252 (1999).
    • (1999) J. Clin. Invest. , vol.104 , pp. 239-252
    • Bishopric, N.H.1
  • 37
    • 33845764296 scopus 로고    scopus 로고
    • A guided tour into subcellular colocalization analysis in light microscopy
    • Bolte, S. & Cordelieres, F. P. A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224, 213-232 (2006).
    • (2006) J. Microsc. , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelieres, F.P.2
  • 38
    • 84887610189 scopus 로고    scopus 로고
    • Statistical tests for measures of colocalization in biological microscopy
    • McDonald, J. H. & Dunn, K. W. Statistical tests for measures of colocalization in biological microscopy. J. Microsc. 252, 295-302 (2013).
    • (2013) J. Microsc. , vol.252 , pp. 295-302
    • McDonald, J.H.1    Dunn, K.W.2
  • 39
    • 0030773141 scopus 로고    scopus 로고
    • A simple method for preparation of cultured cardiac fibroblasts from adult human ventricular tissue
    • Agocha, A. E. & Eghbali-Webb, M. A simple method for preparation of cultured cardiac fibroblasts from adult human ventricular tissue. Mol. Cell. Biochem. 172, 195-198 (1997).
    • (1997) Mol. Cell. Biochem. , vol.172 , pp. 195-198
    • Agocha, A.E.1    Eghbali-Webb, M.2
  • 40
    • 0021058742 scopus 로고
    • In vivo and in vitro uptake and degradation of acetylated lowdensity lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells
    • Nagelkerke, J. F., Barto, K. P. & van Berkel, T. J. In vivo and in vitro uptake and degradation of acetylated lowdensity lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells. J. Biol. Chem. 258, 12221-12227 (1983).
    • (1983) J. Biol. Chem. , vol.258 , pp. 12221-12227
    • Nagelkerke, J.F.1    Barto, K.P.2    Van Berkel, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.