Candidate Gene Approach Identifies Multiple Genes and Signaling Pathways Downstream of Tbx4 in the Developing Allantois

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Arora, Ripla ^a   del Alcazar, Chelsea M ^a   Morrisey, Edward E ^b   Naiche, L A ^c   Papaioannou, Virginia E ^a  

^a NewYork Presbyterian Hospital   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; JAGGED1; NOTCH2 RECEPTOR; OSTEOGENIC PROTEIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX4; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG; WNT PROTEIN; WNT2 PROTEIN;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; BMP2 GENE; BMP7 GENE; CHORIOALLANTOIS; CONTROLLED STUDY; EMBRYO; EX VIVO STUDY; FEMALE; FETUS MEMBRANE; GENE; HAS2 GENE; IN VIVO STUDY; ITG ALPHA5 GENE; JAG1 GENE; MOUSE; MUTANT; NONHUMAN; NOTCH2 GENE; PLACENTA; SIGNAL TRANSDUCTION; SNAI1 GENE; TBX4 GENE; TWIST GENE; VCAN GENE; WILD TYPE; WNT2 GENE;

ALLANTOIS; ANIMALS; CROSSES, GENETIC; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; MUTATION; PREGNANCY; PREGNANCY, ANIMAL; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; TIME FACTORS; UMBILICAL VEINS; WNT PROTEINS;

EID: 84865526814     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043581     Document Type: Article

References (46)

1. Downs KM, Bertler C, (2000) Growth in the pre-fusion murine allantois. Anat Embryol (Berl) 202: 323-331.
2. Downs KM, Hellman ER, McHugh J, Barrickman K, Inman KE, (2004) Investigation into a role for the primitive streak in development of the murine allantois. Development 131: 37-55.
3. Inman KE, Downs KM, (2007) The murine allantois: emerging paradigms in development of the mammalian umbilical cord and its relation to the fetus. Genesis 45: 237-258.
4. Downs KM, Gifford S, Blahnik M, Gardner RL, (1998) Vascularization in the murine allantois occurs by vasculogenesis without accompanying erythropoiesis. Development 125: 4507-4520.
5. Drake CJ, Fleming PA, (2000) Vasculogenesis in the day 6.5 to 9.5 mouse embryo. Blood 95: 1671-1679.
6. Patan S, (2000) Vasculogenesis and angiogenesis as mechanisms of vascular network formation, growth and remodeling. J Neurooncol 50: 1-15.
7. George EL, Georges-Labouesse EN, Patel-King RS, Rayburn H, Hynes RO, (1993) Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development 119: 1079-1091.
8. Giros A, Grgur K, Gossler A, Costell M, (2011) α5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice. PLoS One 6: e22002.
9. Jungers KA, Le Goff C, Somerville RP, Apte SS, (2005) Adamts9 is widely expressed during mouse embryo development. Gene Expr Patterns 5: 609-617.
10. Brown JJG, Papaioannou VE, (1993) Ontogeny of hyaluronan secretion during early mouse development. Development 117: 483-492.
11. Watson ED, Cross JC, (2005) Development of structures and transport functions in the mouse placenta. Physiology (Bethesda) 20: 180-193.
12. Naiche LA, Papaioannou VE, (2003) Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois. Development 130: 2681-2693.
13. Naiche LA, Arora R, Kania A, Lewandoski M, Papaioannou VE, (2011) Identity and fate of Tbx4-expressing cells reveal developmental cell fate decisions in the allantois, limb, and external genitalia. Dev Dyn 240: 2290-2300.
14. Argraves WS, Drake CJ, (2005) Genes critical to vasculogenesis as defined by systematic analysis of vascular defects in knockout mice. Anat Rec A Discov Mol Cell Evol Biol 286: 875-884.
15. Camenisch TD, Spicer AP, Brehm-Gibson T, Biesterfeldt J, Augustine ML, et al. (2000) Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme. J Clin Invest 106: 349-360.
16. Fenderson BA, Stamenkovic I, Aruffo A, (1993) Localization of hyaluronan in mouse embryos during implantation, gastrulation and organogenesis. Differentiation 54: 85-98.
17. Yamamura H, Zhang M, Markwald RR, Mjaatvedt CH, (1997) A heart segmental defect in the anterior-posterior axis of a transgenic mutant mouse. Dev Biol 186: 58-72.
18. Francis SE, Goh KL, Hodivala-Dilke K, Bader BL, Stark M, et al. (2002) Central roles of α5β1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arterioscler Thromb Vasc Biol 22: 927-933.
19. Zhang H, Bradley A, (1996) Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 122: 2977-2986.
20. Solloway MJ, Robertson EJ, (1999) Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development 126: 1753-1768.
21. Monkley SJ, Delaney SJ, Pennisi DJ, Christiansen JH, Wainwright BJ, (1996) Targeted disruption of the Wnt2 gene results in placentation defects. Development 122: 3343-3353.
22. Hamada Y, Kadokawa Y, Okabe M, Ikawa M, Coleman JR, et al. (1999) Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development 126: 3415-3424.
23. Gale NW, Dominguez MG, Noguera I, Pan L, Hughes V, et al. (2004) Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. Proc Natl Acad Sci U S A 101: 15949-15954.
24. Xue Y, Gao X, Lindsell CE, Norton CR, Chang B, et al. (1999) Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum Mol Genet 8: 723-730.
25. Leptin M, (1991) twist and snail as positive and negative regulators during Drosophila mesoderm development. Genes Dev 5: 1568-1576.
26. Lomeli H, Starling C, Gridley T, (2009) Epiblast-specific Snai1 deletion results in embryonic lethality due to multiple vascular defects. BMC Res Notes 2: 22.
27. Crosby CV, Fleming PA, Argraves WS, Corada M, Zanetta L, et al. (2005) VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly. Blood 105: 2771-2776.
28. Downs KM, Temkin R, Gifford S, McHugh J, (2001) Study of the murine allantois by allantoic explants. Dev Biol 233: 347-364.
29. Rao AS, Kremenevskaja N, Resch J, Brabant G, (2005) Lithium stimulates proliferation in cultured thyrocytes by activating Wnt/beta-catenin signalling. Eur J Endocrinol 153: 929-938.
30. McGill R, Tukey JW, Larsen WA, (1978) Variations of box plots. The American Statistician 32: 12-16.
31. Karner CM, Merkel CE, Dodge M, Ma Z, Lu J, et al. (2010) Tankyrase is necessary for canonical Wnt signaling during kidney development. Dev Dyn 239: 2014-2023.
32. Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, et al. (2001) Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128: 1253-1264.
33. Papaioannou VE, Goldin SN (2008) Introduction to the T-box genes and their roles in developmental signaling pathways. In: Epstein CJ, Erickson RP, Wynshaw-Boris A, editors. Inborn Errors of Development The Molecular Basis of Clinical Disorders of Morphogenesis, 2nd Edition. Oxford: Oxford University Press. 852-861.
34. Ghosh TK, Packham EA, Bonser AJ, Robinson TE, Cross SJ, et al. (2001) Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum Mol Genet 10: 1983-1994.
35. Hooghe B, Hulpiau P, van Roy F, De Bleser P, (2008) ConTra: a promoter alignment analysis tool for identification of transcription factor binding sites across species. Nucleic Acids Res 36: W128-132.
36. Wang H, Gilner JB, Bautch VL, Wang DZ, Wainwright BJ, et al. (2007) Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies. J Biol Chem 282: 782-791.
37. Klein D, Demory A, Peyre F, Kroll J, Augustin HG, et al. (2008) Wnt2 acts as a cell type-specific, autocrine growth factor in rat hepatic sinusoidal endothelial cells cross-stimulating the VEGF pathway. Hepatology 47: 1018-1031.
38. Cattelino A, Liebner S, Gallini R, Zanetti A, Balconi G, et al. (2003) The conditional inactivation of the β-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility. J Cell Biol 162: 1111-1122.
39. Scotti M, Kmita M, (2012) Recruitment of 5′ Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammals. Development 139: 731-739.
40. Aoki M, Mieda M, Ikeda T, Hamada Y, Nakamura H, et al. (2007) R-spondin3 is required for mouse placental development. Dev Biol 301: 218-226.
41. Ishikawa T, Tamai Y, Zorn AM, Yoshida H, Seldin MF, et al. (2001) Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development 128: 25-33.
42. Goss AM, Tian Y, Tsukiyama T, Cohen ED, Zhou D, et al. (2009) Wnt2/2b and β-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Developmental Cell 17: 290-298.
43. Davis CA, (1993) Whole-mount immunohistochemistry. Methods Enzymol 225: 502-516.
44. Wilkinson DG, Nieto MA, (1993) Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods Enzymol 225: 361-373.
45. Ouimette JF, Jolin ML, L'Honore A, Gifuni A, Drouin J, (2010) Divergent transcriptional activities determine limb identity. Nat Commun 1: 35.
46. Gebelein B, Urrutia R, (2001) Sequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Kruppel-associated box protein. Mol Cell Biol 21: 928-939.