메뉴 건너뛰기




Volumn 30, Issue 10, 2016, Pages 931-949

Therapeutic Mechanisms of Lithium in Bipolar Disorder: Recent Advances and Current Understanding

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ACETYLCHOLINE; ADENYLATE CYCLASE; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM; CYCLIC AMP; DOPAMINE; DOPAMINE RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLUTAMIC ACID; GLYCINE; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; MARCKS PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTROPHIC FACTOR; PHOSPHATIDYLINOSITIDE; PROTEIN KINASE C; GSK3B PROTEIN, HUMAN; LITHIUM DERIVATIVE; TRANQUILIZER;

EID: 84987644131     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.1007/s40263-016-0380-1     Document Type: Review
Times cited : (93)

References (137)
  • 1
    • 84876930720 scopus 로고    scopus 로고
    • Potential mechanisms of action of lithium in bipolar disorder. Current understanding
    • PID: 23371914
    • Malhi GS, Tanious M, Das P, Coulston CM, Berk M. Potential mechanisms of action of lithium in bipolar disorder. Current understanding. CNS Drugs. 2013;27:135–53.
    • (2013) CNS Drugs. , vol.27 , pp. 135-153
    • Malhi, G.S.1    Tanious, M.2    Das, P.3    Coulston, C.M.4    Berk, M.5
  • 2
    • 67649199656 scopus 로고    scopus 로고
    • Neuroprogression: pathways to progressive brain changes in bipolar disorder
    • COI: 1:CAS:528:DC%2BD1MXkslKlsbw%3D, PID: 18922203
    • Berk M. Neuroprogression: pathways to progressive brain changes in bipolar disorder. Int J Neuropsychopharmacol. 2009;12:441–5.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 441-445
    • Berk, M.1
  • 3
    • 78649938042 scopus 로고    scopus 로고
    • Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors
    • COI: 1:CAS:528:DC%2BC3cXhsFCrurvO, PID: 20934453
    • Berk M, Kapczinski F, Andreazza AC, Dean OM, Giorlando F, Maes M, et al. Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors. Neurosci Biobehav Rev. 2011;35:804–17.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 804-817
    • Berk, M.1    Kapczinski, F.2    Andreazza, A.C.3    Dean, O.M.4    Giorlando, F.5    Maes, M.6
  • 4
    • 84922221879 scopus 로고    scopus 로고
    • All the world’s a (clinical) stage: rethinking bipolar disorder from a longitudinal perspective
    • COI: 1:STN:280:DC%2BC2cbks1eruw%3D%3D, PID: 25048003
    • Frank E, Nimgaonkar VL, Phillips ML, Kupfer DJ. All the world’s a (clinical) stage: rethinking bipolar disorder from a longitudinal perspective. Mol Psychiatry. 2015;20:23–31.
    • (2015) Mol Psychiatry. , vol.20 , pp. 23-31
    • Frank, E.1    Nimgaonkar, V.L.2    Phillips, M.L.3    Kupfer, D.J.4
  • 5
    • 84891805748 scopus 로고    scopus 로고
    • Neuroprotective effect of lithium on hippocampal volumes in bipolar disorder independent of long-term treatment response
    • COI: 1:STN:280:DC%2BC3snotFOnug%3D%3D, PID: 23721695
    • Hajek T, Bauer M, Simhandl C, Rybakowski J, O’Donovan C, Pfennig A, et al. Neuroprotective effect of lithium on hippocampal volumes in bipolar disorder independent of long-term treatment response. Psychol Med. 2014;44:507–17.
    • (2014) Psychol Med , vol.44 , pp. 507-517
    • Hajek, T.1    Bauer, M.2    Simhandl, C.3    Rybakowski, J.4    O’Donovan, C.5    Pfennig, A.6
  • 6
    • 84898752877 scopus 로고    scopus 로고
    • The NIMH Research Domain Criteria (RDoC) project: precision medicine for psychiatry
    • PID: 24687194
    • Insel TR. The NIMH Research Domain Criteria (RDoC) project: precision medicine for psychiatry. Am J Psychiatry. 2014;171:395–7.
    • (2014) Am J Psychiatry , vol.171 , pp. 395-397
    • Insel, T.R.1
  • 7
    • 84959851997 scopus 로고    scopus 로고
    • A review of the current nomenclature for psychotropic agents and an introduction to the neuroscience-based nomenclature
    • COI: 1:CAS:528:DC%2BC2MXhsV2ns7fK, PID: 26527055
    • Zohar J, Stahl S, Möller H-J, Blier P, Kupfer D, Yamawaki S, et al. A review of the current nomenclature for psychotropic agents and an introduction to the neuroscience-based nomenclature. Eur Neuropsychopharmacol. 2015;25:2318–25.
    • (2015) Eur Neuropsychopharmacol , vol.25 , pp. 2318-2325
    • Zohar, J.1    Stahl, S.2    Möller, H.-J.3    Blier, P.4    Kupfer, D.5    Yamawaki, S.6
  • 8
    • 66649103006 scopus 로고    scopus 로고
    • Lithium specificity in bipolar illness: a classic agent for the classic disorder
    • COI: 1:CAS:528:DC%2BD1MXhtVGit7jK, PID: 19538684
    • Gershon S, Chengappa KR, Malhi GS. Lithium specificity in bipolar illness: a classic agent for the classic disorder. Bipolar Disord. 2009;11:34–44.
    • (2009) Bipolar Disord , vol.11 , pp. 34-44
    • Gershon, S.1    Chengappa, K.R.2    Malhi, G.S.3
  • 9
    • 84905919989 scopus 로고    scopus 로고
    • Are ‘buy-polar’ forces and “try-polar” thinking expanding bipolarity?
    • PID: 25048651
    • Malhi GS, Porter RJ. Are ‘buy-polar’ forces and “try-polar” thinking expanding bipolarity? Aust N Z J Psychiatry. 2014;48:697–700.
    • (2014) Aust N Z J Psychiatry , vol.48 , pp. 697-700
    • Malhi, G.S.1    Porter, R.J.2
  • 10
    • 84903531152 scopus 로고    scopus 로고
    • Diagnosing bipolar disorder: defining thresholds and setting boundaries
    • PID: 24875168
    • Malhi GS, Berk M. Diagnosing bipolar disorder: defining thresholds and setting boundaries. Aust N Z J Psychiatry. 2014;48:500–4.
    • (2014) Aust N Z J Psychiatry , vol.48 , pp. 500-504
    • Malhi, G.S.1    Berk, M.2
  • 12
    • 84945914083 scopus 로고    scopus 로고
    • Trends in diagnosis of bipolar disorder: have the boundaries changed?
    • PID: 26450942
    • Sara GE, Malhi GS. Trends in diagnosis of bipolar disorder: have the boundaries changed? Aust N Z J Psychiatry. 2015;49:1021–8.
    • (2015) Aust N Z J Psychiatry , vol.49 , pp. 1021-1028
    • Sara, G.E.1    Malhi, G.S.2
  • 13
    • 84909992917 scopus 로고    scopus 로고
    • Carving bipolarity using a lithium sword
    • PID: 25368357
    • Malhi GS, Geddes JR. Carving bipolarity using a lithium sword. Br J Psychiatry. 2014;205:337–9.
    • (2014) Br J Psychiatry. , vol.205 , pp. 337-339
    • Malhi, G.S.1    Geddes, J.R.2
  • 14
    • 77957359472 scopus 로고    scopus 로고
    • Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial
    • PID: 20092882
    • Geddes JR, Goodwin GM, Rendell J, Azorin J-M, Cipriani A, Ostacher MJ, et al. Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial. Lancet. 2010;375:385–95.
    • (2010) Lancet , vol.375 , pp. 385-395
    • Geddes, J.R.1    Goodwin, G.M.2    Rendell, J.3    Azorin, J.-M.4    Cipriani, A.5    Ostacher, M.J.6
  • 15
    • 84898753546 scopus 로고    scopus 로고
    • A prospective 4-year naturalistic follow-up of treatment and outcome of 300 bipolar I and II patients
    • Simhandl C, König B, Amann BL. A prospective 4-year naturalistic follow-up of treatment and outcome of 300 bipolar I and II patients. J Clin Psychiatry. 2014;75:254–62 (quiz 263).
    • (2014) J Clin Psychiatry , vol.254-62 , Issue.quiz 263 , pp. 75
    • Simhandl, C.1    König, B.2    Amann, B.L.3
  • 16
    • 84871429643 scopus 로고    scopus 로고
    • Lithium and GSK3-β promoter gene variants influence white matter microstructure in bipolar disorder
    • COI: 1:CAS:528:DC%2BC38XhvVOrsLvP, PID: 22990942
    • Benedetti F, Bollettini I, Barberi I, Radaelli D, Poletti S, Locatelli C, et al. Lithium and GSK3-β promoter gene variants influence white matter microstructure in bipolar disorder. Neuropsychopharmacology. 2013;38:313–27.
    • (2013) Neuropsychopharmacology. , vol.38 , pp. 313-327
    • Benedetti, F.1    Bollettini, I.2    Barberi, I.3    Radaelli, D.4    Poletti, S.5    Locatelli, C.6
  • 17
    • 84925363870 scopus 로고    scopus 로고
    • Haplotype analysis of GSK-3β gene polymorphisms in bipolar disorder lithium responders and nonresponders
    • COI: 1:CAS:528:DC%2BC2cXhtFylu7nN, PID: 24992082
    • Iwahashi K, Nishizawa D, Narita S, Numajiri M, Murayama O, Yoshihara E, et al. Haplotype analysis of GSK-3β gene polymorphisms in bipolar disorder lithium responders and nonresponders. Clin Neuropharmacol. 2014;37:108–10.
    • (2014) Clin Neuropharmacol , vol.37 , pp. 108-110
    • Iwahashi, K.1    Nishizawa, D.2    Narita, S.3    Numajiri, M.4    Murayama, O.5    Yoshihara, E.6
  • 18
    • 84940398568 scopus 로고    scopus 로고
    • TRPM2, a susceptibility gene for bipolar disorder, regulates glycogen synthase kinase-3 activity in the brain
    • COI: 1:CAS:528:DC%2BC2MXhslerurfK, PID: 26311765
    • Jang Y, Lee SH, Lee B, Jung S, Khalid A, Uchida K, et al. TRPM2, a susceptibility gene for bipolar disorder, regulates glycogen synthase kinase-3 activity in the brain. J Neurosci. 2015;35:11811–23.
    • (2015) J Neurosci , vol.35 , pp. 11811-11823
    • Jang, Y.1    Lee, S.H.2    Lee, B.3    Jung, S.4    Khalid, A.5    Uchida, K.6
  • 19
    • 84924330827 scopus 로고    scopus 로고
    • Lithium increases platelet serine-9 phosphorylated GSK-3β levels in drug-free bipolar disorder during depressive episodes
    • PID: 25691093
    • de Sousa RT, Zanetti MV, Talib LL, Serpa MH, Chaim TM, Carvalho AF, et al. Lithium increases platelet serine-9 phosphorylated GSK-3β levels in drug-free bipolar disorder during depressive episodes. J Psychiatr Res. 2015;62:78–83.
    • (2015) J Psychiatr Res , vol.62 , pp. 78-83
    • de Sousa, R.T.1    Zanetti, M.V.2    Talib, L.L.3    Serpa, M.H.4    Chaim, T.M.5    Carvalho, A.F.6
  • 20
    • 84875364194 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β gene polymorphisms may be associated with bipolar I disorder and the therapeutic response to lithium
    • COI: 1:CAS:528:DC%2BC38XhsVemtbnL, PID: 23021822
    • Lin Y-F, Huang M-C, Liu H-C. Glycogen synthase kinase 3β gene polymorphisms may be associated with bipolar I disorder and the therapeutic response to lithium. J Affect Disord. 2013;147:401–6.
    • (2013) J Affect Disord , vol.147 , pp. 401-406
    • Lin, Y.-F.1    Huang, M.-C.2    Liu, H.-C.3
  • 21
    • 84884672711 scopus 로고    scopus 로고
    • Differential effects of glycogen synthase kinase 3 (GSK3) inhibition by lithium or selective inhibitors in the central nervous system
    • COI: 1:CAS:528:DC%2BC3sXhsVCitL7J
    • Caberlotto L, Carboni L, Zanderigo F, Andreetta F, Andreoli M, Gentile G, et al. Differential effects of glycogen synthase kinase 3 (GSK3) inhibition by lithium or selective inhibitors in the central nervous system. Naunyn Schmiedeberg’s Arch Pharmacol. 2013;386:893–903.
    • (2013) Naunyn Schmiedeberg’s Arch Pharmacol. , vol.386 , pp. 893-903
    • Caberlotto, L.1    Carboni, L.2    Zanderigo, F.3    Andreetta, F.4    Andreoli, M.5    Gentile, G.6
  • 22
    • 84855354830 scopus 로고    scopus 로고
    • Chronic stress affects PERIOD2 expression through glycogen synthase kinase-3β phosphorylation in the central clock
    • COI: 1:CAS:528:DC%2BC38XhtFClug%3D%3D, PID: 22158133
    • Kinoshita C, Miyazaki K, Ishida N. Chronic stress affects PERIOD2 expression through glycogen synthase kinase-3β phosphorylation in the central clock. NeuroReport. 2012;23:98–102.
    • (2012) NeuroReport , vol.23 , pp. 98-102
    • Kinoshita, C.1    Miyazaki, K.2    Ishida, N.3
  • 23
    • 84904720392 scopus 로고    scopus 로고
    • Lithium potentiates GSK-3β activity by inhibiting phosphoinositide 3-kinase-mediated Akt phosphorylation
    • COI: 1:CAS:528:DC%2BC2cXhtVKhtb%2FO, PID: 24950409
    • Tian N, Kanno T, Jin Y, Nishizaki T. Lithium potentiates GSK-3β activity by inhibiting phosphoinositide 3-kinase-mediated Akt phosphorylation. Biochem Biophys Res Commun. 2014;450:746–9.
    • (2014) Biochem Biophys Res Commun. , vol.450 , pp. 746-749
    • Tian, N.1    Kanno, T.2    Jin, Y.3    Nishizaki, T.4
  • 24
    • 84874388903 scopus 로고    scopus 로고
    • Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum
    • COI: 1:CAS:528:DC%2BC3sXktlShu7k%3D, PID: 23380502
    • Harrison LM, Muller SH, Spano D. Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum. Neuroscience. 2013;236:21–30.
    • (2013) Neuroscience , vol.236 , pp. 21-30
    • Harrison, L.M.1    Muller, S.H.2    Spano, D.3
  • 25
    • 84940884250 scopus 로고    scopus 로고
    • Lithium protects against methamphetamine-induced neurotoxicity in PC12 cells via Akt/GSK3β/mTOR pathway
    • COI: 1:CAS:528:DC%2BC2MXhtlOmtb3P, PID: 26271595
    • Wu J, Zhu D, Zhang J, Li G, Liu Z, Sun J. Lithium protects against methamphetamine-induced neurotoxicity in PC12 cells via Akt/GSK3β/mTOR pathway. Biochem Biophys Res Commun. 2015;465:368–73.
    • (2015) Biochem Biophys Res Commun. , vol.465 , pp. 368-373
    • Wu, J.1    Zhu, D.2    Zhang, J.3    Li, G.4    Liu, Z.5    Sun, J.6
  • 26
    • 84925100862 scopus 로고    scopus 로고
    • Acute and chronic effects of lithium on BDNF and GDNF mRNA and protein levels in rat primary neuronal, astroglial and neuroastroglia cultures
    • PID: 25945236
    • Emamghoreishi M, Keshavarz M, Nekooeian AA. Acute and chronic effects of lithium on BDNF and GDNF mRNA and protein levels in rat primary neuronal, astroglial and neuroastroglia cultures. Iran J Basic Med Sci. 2015;18:240–6.
    • (2015) Iran J Basic Med Sci. , vol.18 , pp. 240-246
    • Emamghoreishi, M.1    Keshavarz, M.2    Nekooeian, A.A.3
  • 27
    • 84902094471 scopus 로고    scopus 로고
    • Alterations in BDNF (brain derived neurotrophic factor) and GDNF (glial cell line-derived neurotrophic factor) serum levels in bipolar disorder: the role of lithium
    • COI: 1:CAS:528:DC%2BC2cXhtFWnu7jO, PID: 25012431
    • Tunca Z, Ozerdem A, Ceylan D, Yalçın Y, Can G, Resmi H, et al. Alterations in BDNF (brain derived neurotrophic factor) and GDNF (glial cell line-derived neurotrophic factor) serum levels in bipolar disorder: the role of lithium. J Affect Disord. 2014;166:193–200.
    • (2014) J Affect Disord , vol.166 , pp. 193-200
    • Tunca, Z.1    Ozerdem, A.2    Ceylan, D.3    Yalçın, Y.4    Can, G.5    Resmi, H.6
  • 28
    • 84894764070 scopus 로고    scopus 로고
    • Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania
    • Stertz L, Fries GR, Aguiar BW de, Pfaffenseller B, Valvassori SS, Gubert C, et al. Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania. Rev Bras Psiquiatr. 2014;36:39–46.
    • (2014) Rev Bras Psiquiatr , vol.36 , pp. 39-46
    • Stertz, L.1    Fries, G.R.2    Aguiar, B.W.3
  • 29
    • 84941316626 scopus 로고    scopus 로고
    • Protective effect of lithium chloride against trimethyltin-induced hippocampal degeneration and comorbid depression in rats
    • Moghadas M, Edalatmanesh MA. Protective effect of lithium chloride against trimethyltin-induced hippocampal degeneration and comorbid depression in rats. Comp Clin Pathol. 2014;24:1165–75.
    • (2014) Comp Clin Pathol , vol.24 , pp. 1165-1175
    • Moghadas, M.1    Edalatmanesh, M.A.2
  • 30
    • 84925461107 scopus 로고    scopus 로고
    • Synergistic effects of GSK-3β and HDAC inhibitors in intracerebroventricular streptozotocin-induced cognitive deficits in rats
    • Sharma S, Taliyan R. Synergistic effects of GSK-3β and HDAC inhibitors in intracerebroventricular streptozotocin-induced cognitive deficits in rats. Naunyn Schmiedeberg’s Arch Pharmacol. 2014;388:337–49.
    • (2014) Naunyn Schmiedeberg’s Arch Pharmacol , vol.388 , pp. 337-349
    • Sharma, S.1    Taliyan, R.2
  • 31
    • 84901806913 scopus 로고    scopus 로고
    • Effects of lithium and valproic acid on BDNF protein and gene expression in an in vitro human neuron-like model of degeneration
    • COI: 1:CAS:528:DC%2BC2MXisFSntbY%3D, PID: 24699060
    • Croce N, Mathé AA, Gelfo F, Caltagirone C, Bernardini S, Angelucci F. Effects of lithium and valproic acid on BDNF protein and gene expression in an in vitro human neuron-like model of degeneration. J Psychopharmacol. 2014;28:964–72.
    • (2014) J Psychopharmacol. , vol.28 , pp. 964-972
    • Croce, N.1    Mathé, A.A.2    Gelfo, F.3    Caltagirone, C.4    Bernardini, S.5    Angelucci, F.6
  • 32
    • 84888138476 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor serum concentrations in acute depressive patients increase during lithium augmentation of antidepressants
    • COI: 1:CAS:528:DC%2BC3sXhslCqurfO, PID: 24018547
    • Ricken R, Adli M, Lange C, Krusche E, Stamm TJ, Gaus S, et al. Brain-derived neurotrophic factor serum concentrations in acute depressive patients increase during lithium augmentation of antidepressants. J Clin Psychopharmacol. 2013;33:806–9.
    • (2013) J Clin Psychopharmacol , vol.33 , pp. 806-809
    • Ricken, R.1    Adli, M.2    Lange, C.3    Krusche, E.4    Stamm, T.J.5    Gaus, S.6
  • 33
    • 84858246435 scopus 로고    scopus 로고
    • A polymorphism associated with depressive disorders differentially regulates brain derived neurotrophic factor promoter IV activity
    • COI: 1:CAS:528:DC%2BC38XjvVeksbY%3D, PID: 22265241
    • Hing B, Davidson S, Lear M, Breen G, Quinn J, McGuffin P, et al. A polymorphism associated with depressive disorders differentially regulates brain derived neurotrophic factor promoter IV activity. Biol Psychiatry. 2012;71:618–26.
    • (2012) Biol Psychiatry , vol.71 , pp. 618-626
    • Hing, B.1    Davidson, S.2    Lear, M.3    Breen, G.4    Quinn, J.5    McGuffin, P.6
  • 34
    • 84921718522 scopus 로고    scopus 로고
    • Lithium-induced neuroprotection is associated with epigenetic modification of specific BDNF gene promoter and altered expression of apoptotic-regulatory proteins
    • Dwivedi T, Zhang H. Lithium-induced neuroprotection is associated with epigenetic modification of specific BDNF gene promoter and altered expression of apoptotic-regulatory proteins. Front Neurosci. 2015;8:525.
    • (2015) Front Neurosci , vol.8 , pp. 525
    • Dwivedi, T.1    Zhang, H.2
  • 35
    • 84868669804 scopus 로고    scopus 로고
    • Effects of lithium and valproate on oxidative stress and behavioral changes induced by administration of m-AMPH
    • da-Rosa DD, Valvassori SS, Steckert AV, Ornell F, Ferreira CL, Lopes-Borges J, et al. Effects of lithium and valproate on oxidative stress and behavioral changes induced by administration of m-AMPH. Psychiatry Res. 2012;198:521–6.
    • (2012) Psychiatry Res , vol.198 , pp. 521-526
    • da-Rosa, D.D.1    Valvassori, S.S.2    Steckert, A.V.3    Ornell, F.4    Ferreira, C.L.5    Lopes-Borges, J.6
  • 36
    • 84873284223 scopus 로고    scopus 로고
    • Effects of lithium on oxidative stress and behavioral alterations induced by lisdexamfetamine dimesylate: relevance as an animal model of mania
    • PID: 23333378
    • Macêdo DS, de Lucena DF, Queiroz AIG, Cordeiro RC, Araújo MM, Sousa FC, et al. Effects of lithium on oxidative stress and behavioral alterations induced by lisdexamfetamine dimesylate: relevance as an animal model of mania. Prog Neuropsychopharmacol Biol Psychiatry. 2013;43:230–7.
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.43 , pp. 230-237
    • Macêdo, D.S.1    de Lucena, D.F.2    Queiroz, A.I.G.3    Cordeiro, R.C.4    Araújo, M.M.5    Sousa, F.C.6
  • 37
    • 84859454613 scopus 로고    scopus 로고
    • 3′-5′ Phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo
    • Toledano E, Ogryzko V, Danchin A, Ladant D, Mechold U. 3′-5′ Phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo. Biochem J. 2012;443:485–90.
    • (2012) Biochem J , vol.443 , pp. 485-490
    • Toledano, E.1    Ogryzko, V.2    Danchin, A.3    Ladant, D.4    Mechold, U.5
  • 38
  • 39
    • 84876665625 scopus 로고    scopus 로고
    • Lithium’s gene expression profile, relevance to neuroprotection A cDNA microarray study
    • Farah R, Khamisy-Farah R, Amit T, Youdim MBH, Arraf Z. Lithium’s gene expression profile, relevance to neuroprotection A cDNA microarray study. Cell Mol Neurobiol. 2013;33:411–20.
    • (2013) Cell Mol Neurobiol , vol.33 , pp. 411-420
    • Farah, R.1    Khamisy-Farah, R.2    Amit, T.3    Youdim, M.B.H.4    Arraf, Z.5
  • 40
    • 84875958002 scopus 로고    scopus 로고
    • Neuroprotective effects of chronic exposure of SH-SY5Y to low lithium concentration involve glycolysis stimulation, extracellular pyruvate accumulation and resistance to oxidative stress
    • COI: 1:CAS:528:DC%2BC3sXksFKksbY%3D, PID: 22436355
    • Nciri R, Desmoulin F, Allagui MS, Murat J-C, Feki AE, Vincent C, et al. Neuroprotective effects of chronic exposure of SH-SY5Y to low lithium concentration involve glycolysis stimulation, extracellular pyruvate accumulation and resistance to oxidative stress. Int J Neuropsychopharmacol. 2013;16:365–76.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 365-376
    • Nciri, R.1    Desmoulin, F.2    Allagui, M.S.3    Murat, J.-C.4    Feki, A.E.5    Vincent, C.6
  • 41
    • 84882365547 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3β by lithium chloride suppresses 6-hydroxydopamine-induced inflammatory response in primary cultured astrocytes
    • COI: 1:CAS:528:DC%2BC3sXhs1KitLzO, PID: 23871716
    • Wang H-M, Zhang T, Li Q, Huang J-K, Chen R-F, Sun X-J. Inhibition of glycogen synthase kinase-3β by lithium chloride suppresses 6-hydroxydopamine-induced inflammatory response in primary cultured astrocytes. Neurochem Int. 2013;63:345–53.
    • (2013) Neurochem Int , vol.63 , pp. 345-353
    • Wang, H.-M.1    Zhang, T.2    Li, Q.3    Huang, J.-K.4    Chen, R.-F.5    Sun, X.-J.6
  • 42
    • 84895525304 scopus 로고    scopus 로고
    • Microarray analysis of global gene expression in leukocytes following lithium treatment
    • COI: 1:CAS:528:DC%2BC2cXjvVyhtrs%3D, PID: 24590544
    • Watanabe S, Iga J, Nishi A, Numata S, Kinoshita M, Kikuchi K, et al. Microarray analysis of global gene expression in leukocytes following lithium treatment. Hum Psychopharmacol. 2014;29:190–8.
    • (2014) Hum Psychopharmacol , vol.29 , pp. 190-198
    • Watanabe, S.1    Iga, J.2    Nishi, A.3    Numata, S.4    Kinoshita, M.5    Kikuchi, K.6
  • 44
    • 84952871274 scopus 로고    scopus 로고
    • Impact of lithium alone or in combination with haloperidol on oxidative stress parameters and cell viability in SH-SY5Y cell culture
    • Gawlik-Kotelnicka O, Mielicki W, Rabe-Jabłońska J, Lazarek J, Strzelecki D. Impact of lithium alone or in combination with haloperidol on oxidative stress parameters and cell viability in SH-SY5Y cell culture. Acta Neuropsychiatrica. 2016;28:38–44.
    • (2016) Acta Neuropsychiatrica , vol.28 , pp. 38-44
    • Gawlik-Kotelnicka, O.1    Mielicki, W.2    Rabe-Jabłońska, J.3    Lazarek, J.4    Strzelecki, D.5
  • 45
    • 84857789619 scopus 로고    scopus 로고
    • Effects of lithium therapy on Na+-K+-ATPase activity and lipid peroxidation in bipolar disorder
    • COI: 1:CAS:528:DC%2BC38XjsVCgtLo%3D, PID: 22230647
    • Banerjee U, Dasgupta A, Rout JK, Singh OP. Effects of lithium therapy on Na+-K+-ATPase activity and lipid peroxidation in bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2012;37:56–61.
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.37 , pp. 56-61
    • Banerjee, U.1    Dasgupta, A.2    Rout, J.K.3    Singh, O.P.4
  • 46
    • 84892528590 scopus 로고    scopus 로고
    • Oxidative stress in early stage bipolar disorder and the association with response to lithium
    • PID: 24332923
    • de Sousa RT, Zarate CA, Zanetti MV, Costa AC, Talib LL, Gattaz WF, et al. Oxidative stress in early stage bipolar disorder and the association with response to lithium. J Psychiatr Res. 2014;50:36–41.
    • (2014) J Psychiatr Res , vol.50 , pp. 36-41
    • de Sousa, R.T.1    Zarate, C.A.2    Zanetti, M.V.3    Costa, A.C.4    Talib, L.L.5    Gattaz, W.F.6
  • 47
    • 84871520685 scopus 로고    scopus 로고
    • Mood stabilizer lithium inhibits amphetamine-increased 4-hydroxynonenal-protein adducts in rat frontal cortex
    • COI: 1:CAS:528:DC%2BC38Xht1yrtrjE, PID: 21939588
    • Tan H, Young LT, Shao L, Che Y, Honer WG, Wang J-F. Mood stabilizer lithium inhibits amphetamine-increased 4-hydroxynonenal-protein adducts in rat frontal cortex. Int J Neuropsychopharmacol. 2012;15:1275–85.
    • (2012) Int J Neuropsychopharmacol , vol.15 , pp. 1275-1285
    • Tan, H.1    Young, L.T.2    Shao, L.3    Che, Y.4    Honer, W.G.5    Wang, J.-F.6
  • 48
    • 84939872278 scopus 로고    scopus 로고
    • Lithium increases leukocyte mitochondrial complex I activity in bipolar disorder during depressive episodes
    • PID: 24961563
    • de Sousa RT, Streck EL, Zanetti MV, Ferreira GK, Diniz BS, Brunoni AR, et al. Lithium increases leukocyte mitochondrial complex I activity in bipolar disorder during depressive episodes. Psychopharmacology. 2015;232:245–50.
    • (2015) Psychopharmacology , vol.232 , pp. 245-250
    • de Sousa, R.T.1    Streck, E.L.2    Zanetti, M.V.3    Ferreira, G.K.4    Diniz, B.S.5    Brunoni, A.R.6
  • 49
    • 84888103634 scopus 로고    scopus 로고
    • Chronic treatment with the mood-stabilizing drug lithium up-regulates nuclear factor E2-related factor 2 in rat pheochromocytoma PC12 cells in vitro
    • COI: 1:CAS:528:DC%2BC3sXhvFOltrbP, PID: 24505606
    • Rizak J, Tan H, Zhu H, Wang JF. Chronic treatment with the mood-stabilizing drug lithium up-regulates nuclear factor E2-related factor 2 in rat pheochromocytoma PC12 cells in vitro. Neuroscience. 2014;256:223–9.
    • (2014) Neuroscience , vol.256 , pp. 223-229
    • Rizak, J.1    Tan, H.2    Zhu, H.3    Wang, J.F.4
  • 50
    • 84930665355 scopus 로고    scopus 로고
    • Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells
    • PID: 26074776
    • Alural B, Ozerdem A, Allmer J, Genc K, Genc S. Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells. Front Cell Neurosci. 2015;9:209.
    • (2015) Front Cell Neurosci , vol.9 , pp. 209
    • Alural, B.1    Ozerdem, A.2    Allmer, J.3    Genc, K.4    Genc, S.5
  • 51
    • 84947491154 scopus 로고    scopus 로고
    • Antimanic-like activity of candesartan in mice: possible involvement of antioxidant, anti-inflammatory and neurotrophic mechanisms
    • de Souza Gomes JA, de Souza GC, Berk M, Cavalcante LM, de Sousa FCF, Budni J, et al. Antimanic-like activity of candesartan in mice: possible involvement of antioxidant, anti-inflammatory and neurotrophic mechanisms. Eur Neuropsychopharmacol. 2015;25:2086–97.
    • (2015) Eur Neuropsychopharmacol , vol.25 , pp. 2086-2097
    • de Souza Gomes, J.A.1    de Souza, G.C.2    Berk, M.3    Cavalcante, L.M.4    de Sousa, F.C.F.5    Budni, J.6
  • 52
    • 84915748256 scopus 로고    scopus 로고
    • The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis
    • Liechti FD, Stüdle N, Theurillat R, Grandgirard D, Thormann W, Leib SL. The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis. PLoS One. 2014;9:e113607.
    • (2014) PLoS One , vol.e113607 , pp. 9
    • Liechti, F.D.1    Stüdle, N.2    Theurillat, R.3    Grandgirard, D.4    Thormann, W.5    Leib, S.L.6
  • 53
    • 84908042347 scopus 로고    scopus 로고
    • Translocation of glycogen synthase kinase-3β (GSK-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (VDAC2)
    • COI: 1:CAS:528:DC%2BC2cXhslKrtrrI, PID: 25187518
    • Tanno M, Kuno A, Ishikawa S, Miki T, Kouzu H, Yano T, et al. Translocation of glycogen synthase kinase-3β (GSK-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (VDAC2). J Biol Chem. 2014;289:29285–96.
    • (2014) J Biol Chem , vol.289 , pp. 29285-29296
    • Tanno, M.1    Kuno, A.2    Ishikawa, S.3    Miki, T.4    Kouzu, H.5    Yano, T.6
  • 54
    • 84871715443 scopus 로고    scopus 로고
    • Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells
    • COI: 1:CAS:528:DC%2BC3sXjs1Skug%3D%3D, PID: 23161404
    • Ngok-Ngam P, Watcharasit P, Thiantanawat A, Satayavivad J. Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells. Cell Mol Biol Lett. 2013;18:58–74.
    • (2013) Cell Mol Biol Lett , vol.18 , pp. 58-74
    • Ngok-Ngam, P.1    Watcharasit, P.2    Thiantanawat, A.3    Satayavivad, J.4
  • 55
    • 84883303250 scopus 로고    scopus 로고
    • Increased bcl-2 protein levels in rat primary astrocyte culture following chronic lithium treatment
    • PID: 24174697
    • Keshavarz M, Emamghoreishi M, Nekooeian AA, Warsh J, Zare HR. Increased bcl-2 protein levels in rat primary astrocyte culture following chronic lithium treatment. Iran J Med Sci. 2013;38:255–62.
    • (2013) Iran J Med Sci. , vol.38 , pp. 255-262
    • Keshavarz, M.1    Emamghoreishi, M.2    Nekooeian, A.A.3    Warsh, J.4    Zare, H.R.5
  • 56
    • 84897398654 scopus 로고    scopus 로고
    • Gene-expression differences in peripheral blood between lithium responders and non-responders in the Lithium Treatment-Moderate dose Use Study (LiTMUS)
    • PID: 23670706
    • Beech RD, Leffert JJ, Lin A, Sylvia LG, Umlauf S, Mane S, et al. Gene-expression differences in peripheral blood between lithium responders and non-responders in the Lithium Treatment-Moderate dose Use Study (LiTMUS). Pharmacogenomics J. 2013;14:182–91.
    • (2013) Pharmacogenomics J. , vol.14 , pp. 182-191
    • Beech, R.D.1    Leffert, J.J.2    Lin, A.3    Sylvia, L.G.4    Umlauf, S.5    Mane, S.6
  • 57
    • 84864334532 scopus 로고    scopus 로고
    • Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling
    • COI: 1:CAS:528:DC%2BC3MXivVGns7o%3D, PID: 21383773
    • Gupta A, Schulze TG, Nagarajan V, Akula N, Corona W, Jiang X-Y, et al. Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling. Pharmacogenomics J. 2012;12:328–41.
    • (2012) Pharmacogenomics J. , vol.12 , pp. 328-341
    • Gupta, A.1    Schulze, T.G.2    Nagarajan, V.3    Akula, N.4    Corona, W.5    Jiang, X.-Y.6
  • 58
    • 84961132054 scopus 로고    scopus 로고
    • Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement
    • PID: 26608648
    • Hou L, Xiong N, Liu L, Huang J, Han C, Zhang G, et al. Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement. BMC Neurosci. 2015;16:82.
    • (2015) BMC Neurosci. , vol.16 , pp. 82
    • Hou, L.1    Xiong, N.2    Liu, L.3    Huang, J.4    Han, C.5    Zhang, G.6
  • 59
    • 84931578076 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 differentially affects lithium sensitivity of lymphoblastoid cell lines from lithium responder and non-responder bipolar disorder patients
    • COI: 1:CAS:528:DC%2BC2MXjvVGnt7o%3D, PID: 25740013
    • Milanesi E, Hadar A, Maffioletti E, Werner H, Shomron N, Gennarelli M, et al. Insulin-like growth factor 1 differentially affects lithium sensitivity of lymphoblastoid cell lines from lithium responder and non-responder bipolar disorder patients. J Mol Neurosci. 2015;56:681–7.
    • (2015) J Mol Neurosci , vol.56 , pp. 681-687
    • Milanesi, E.1    Hadar, A.2    Maffioletti, E.3    Werner, H.4    Shomron, N.5    Gennarelli, M.6
  • 60
    • 84878410095 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines of lithium responsive bipolar disorder patients
    • COI: 1:CAS:528:DC%2BC3sXosFOhtrc%3D, PID: 23619527
    • Squassina A, Costa M, Congiu D, Manchia M, Angius A, Deiana V, et al. Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines of lithium responsive bipolar disorder patients. Pharmacol Res. 2013;73:1–7.
    • (2013) Pharmacol Res , vol.73 , pp. 1-7
    • Squassina, A.1    Costa, M.2    Congiu, D.3    Manchia, M.4    Angius, A.5    Deiana, V.6
  • 61
    • 84950274907 scopus 로고    scopus 로고
    • The effect of lithium on hematopoietic, mesenchymal and neural stem cells
    • COI: 1:CAS:528:DC%2BC28XhtlSgu7w%3D, PID: 26922521
    • Ferensztajn-Rochowiak E, Rybakowski JK. The effect of lithium on hematopoietic, mesenchymal and neural stem cells. Pharmacol Rep. 2016;68:224–30.
    • (2016) Pharmacol Rep. , vol.68 , pp. 224-230
    • Ferensztajn-Rochowiak, E.1    Rybakowski, J.K.2
  • 62
    • 84958637174 scopus 로고    scopus 로고
    • Differential effect of lithium on cell number in the hippocampus and prefrontal cortex in adult mice: a stereological study
    • COI: 1:CAS:528:DC%2BC28XivFOgtLk%3D, PID: 26842627
    • Rajkowska G, Clarke G, Mahajan G, Licht CM, van de Werd HJ, Yuan P, et al. Differential effect of lithium on cell number in the hippocampus and prefrontal cortex in adult mice: a stereological study. Bipolar Disord. 2016;18:41–51.
    • (2016) Bipolar Disord , vol.18 , pp. 41-51
    • Rajkowska, G.1    Clarke, G.2    Mahajan, G.3    Licht, C.M.4    van de Werd, H.J.5    Yuan, P.6
  • 63
    • 84939172330 scopus 로고    scopus 로고
    • Kara N, Narayanan S, Belmaker RH, Einat H, Vaidya VA, Agam G. Chronic lithium treatment enhances the number of quiescent neural progenitors but not the number of DCX-positive immature neurons. Int J Neuropsychopharmacol. 2015;18:pyv003–3
    • Kara N, Narayanan S, Belmaker RH, Einat H, Vaidya VA, Agam G. Chronic lithium treatment enhances the number of quiescent neural progenitors but not the number of DCX-positive immature neurons. Int J Neuropsychopharmacol. 2015;18:pyv003–3.
  • 64
    • 84913555312 scopus 로고    scopus 로고
    • Lithium chloride stimulates PLP and MBP expression in oligodendrocytes via Wnt/β-catenin and Akt/CREB pathways
    • COI: 1:CAS:528:DC%2BC2cXhvFWgs7bE, PID: 25451297
    • Meffre D, Massaad C, Grenier J. Lithium chloride stimulates PLP and MBP expression in oligodendrocytes via Wnt/β-catenin and Akt/CREB pathways. Neuroscience. 2015;284:962–71.
    • (2015) Neuroscience , vol.284 , pp. 962-971
    • Meffre, D.1    Massaad, C.2    Grenier, J.3
  • 65
    • 84929173955 scopus 로고    scopus 로고
    • Cytoskeleton involvement in lithium-induced SH-SY5Y neuritogenesis and the role of glycogen synthase kinase 3β
    • PID: 25409859
    • Nciri R, Boujbiha MA, Jbahi S, Allagui MS, Elfeki A, Vincent C, et al. Cytoskeleton involvement in lithium-induced SH-SY5Y neuritogenesis and the role of glycogen synthase kinase 3β. Aging Clin Exp Res. 2015;27:255–63.
    • (2015) Aging Clin Exp Res. , vol.27 , pp. 255-263
    • Nciri, R.1    Boujbiha, M.A.2    Jbahi, S.3    Allagui, M.S.4    Elfeki, A.5    Vincent, C.6
  • 66
    • 84916928574 scopus 로고    scopus 로고
    • Lithium prevents aberrant NMDA-induced F-actin reorganization in neurons
    • COI: 1:CAS:528:DC%2BC2cXhvVGgsLbP, PID: 25304495
    • Calabrese B, Halpain S. Lithium prevents aberrant NMDA-induced F-actin reorganization in neurons. NeuroReport. 2014;25:1331–7.
    • (2014) NeuroReport , vol.25 , pp. 1331-1337
    • Calabrese, B.1    Halpain, S.2
  • 67
    • 84861479897 scopus 로고    scopus 로고
    • Chronic treatment with lithium or valproate modulates the expression of Homer1b/c and its related genes Shank and Inositol 1,4,5-trisphosphate receptor
    • PID: 22245542
    • de Bartolomeis A, Tomasetti C, Cicale M, Yuan P-X, Manji HK. Chronic treatment with lithium or valproate modulates the expression of Homer1b/c and its related genes Shank and Inositol 1,4,5-trisphosphate receptor. Eur Neuropsychopharmacol. 2012;22:527–35.
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 527-535
    • de Bartolomeis, A.1    Tomasetti, C.2    Cicale, M.3    Yuan, P.-X.4    Manji, H.K.5
  • 68
    • 84910104889 scopus 로고    scopus 로고
    • Lithium ameliorates lipopolysaccharide-induced microglial activation via inhibition of toll-like receptor 4 expression by activating the PI3K/Akt/FoxO1 pathway
    • Dong H, Zhang X, Dai X, Lu S, Gui B, Jin W, et al. Lithium ameliorates lipopolysaccharide-induced microglial activation via inhibition of toll-like receptor 4 expression by activating the PI3K/Akt/FoxO1 pathway. J Neuroinflamm. 2014;11:140.
    • (2014) J Neuroinflamm. , vol.11 , pp. 140
    • Dong, H.1    Zhang, X.2    Dai, X.3    Lu, S.4    Gui, B.5    Jin, W.6
  • 69
    • 84975106659 scopus 로고    scopus 로고
    • Therapeutic concentration of lithium stimulates complement C3 production in dendritic cells and microglia via GSK-3 inhibition
    • PID: 25179772
    • Yu Z, Ono C, Aiba S, Kikuchi Y, Sora I, Matsuoka H, et al. Therapeutic concentration of lithium stimulates complement C3 production in dendritic cells and microglia via GSK-3 inhibition. Glia. 2015;63:257–70.
    • (2015) Glia. , vol.63 , pp. 257-270
    • Yu, Z.1    Ono, C.2    Aiba, S.3    Kikuchi, Y.4    Sora, I.5    Matsuoka, H.6
  • 70
    • 25444483066 scopus 로고    scopus 로고
    • Lithium induces autophagy by inhibiting inositol monophosphatase
    • COI: 1:CAS:528:DC%2BD2MXhtVKnsbvP, PID: 16186256
    • Sarkar S, Floto RA, Berger Z, Imarisio S, Cordenier A, Pasco M, et al. Lithium induces autophagy by inhibiting inositol monophosphatase. J Cell Biol. 2005;170:1101–11.
    • (2005) J Cell Biol , vol.170 , pp. 1101-1111
    • Sarkar, S.1    Floto, R.A.2    Berger, Z.3    Imarisio, S.4    Cordenier, A.5    Pasco, M.6
  • 71
    • 84925938744 scopus 로고    scopus 로고
    • Molecular effects of lithium are partially mimicked by inositol-monophosphatase (IMPA)1 knockout mice in a brain region-dependent manner
    • COI: 1:STN:280:DC%2BC2MnitFWjsw%3D%3D, PID: 25748680
    • Damri O, Sade Y, Toker L, Bersudsky Y, Belmaker RH, Agam G, et al. Molecular effects of lithium are partially mimicked by inositol-monophosphatase (IMPA)1 knockout mice in a brain region-dependent manner. Eur Neuropsychopharmacol. 2015;25:425–34.
    • (2015) Eur Neuropsychopharmacol , vol.25 , pp. 425-434
    • Damri, O.1    Sade, Y.2    Toker, L.3    Bersudsky, Y.4    Belmaker, R.H.5    Agam, G.6
  • 72
    • 84924423037 scopus 로고    scopus 로고
    • Inositol-deficient food augments a behavioral effect of long-term lithium treatment mediated by inositol monophosphatase inhibition: an animal model with relevance for bipolar disorder
    • COI: 1:CAS:528:DC%2BC2MXjslemurk%3D, PID: 25679134
    • Shtein L, Agam G, Belmaker RH, Bersudsky Y. Inositol-deficient food augments a behavioral effect of long-term lithium treatment mediated by inositol monophosphatase inhibition: an animal model with relevance for bipolar disorder. J Clin Psychopharmacol. 2015;35:175–7.
    • (2015) J Clin Psychopharmacol , vol.35 , pp. 175-177
    • Shtein, L.1    Agam, G.2    Belmaker, R.H.3    Bersudsky, Y.4
  • 74
    • 84952639449 scopus 로고    scopus 로고
    • A longitudinal (6-week) 3T (1)H-MRS study on the effects of lithium treatment on anterior cingulate cortex metabolites in bipolar depression
    • COI: 1:CAS:528:DC%2BC2MXhsFGhtrbE, PID: 26428274
    • Machado-Vieira R, Gattaz WF, Zanetti MV, de Sousa RT, Carvalho AF, Soeiro-de-Souza MG, et al. A longitudinal (6-week) 3T (1)H-MRS study on the effects of lithium treatment on anterior cingulate cortex metabolites in bipolar depression. Eur Neuropsychopharmacol. 2015;25:2311–7.
    • (2015) Eur Neuropsychopharmacol , vol.25 , pp. 2311-2317
    • Machado-Vieira, R.1    Gattaz, W.F.2    Zanetti, M.V.3    de Sousa, R.T.4    Carvalho, A.F.5    Soeiro-de-Souza, M.G.6
  • 75
    • 84923899935 scopus 로고    scopus 로고
    • Calbindin D28k and S100B have a similar interaction site with the lithium-inhibitable enzyme inositol monophosphatase-1: a new drug target site
    • COI: 1:CAS:528:DC%2BC2MXitlWmtbY%3D, PID: 25665147
    • Agam G, Almog O. Calbindin D28k and S100B have a similar interaction site with the lithium-inhibitable enzyme inositol monophosphatase-1: a new drug target site. J Med Chem. 2015;58:2042–4.
    • (2015) J Med Chem , vol.58 , pp. 2042-2044
    • Agam, G.1    Almog, O.2
  • 77
    • 84949908714 scopus 로고    scopus 로고
    • Effect of the putative lithium mimetic ebselen on brain myo-inositol, sleep, and emotional processing in humans
    • Singh N, Sharpley AL, Emir UE, Masaki C, Herzallah MM, Gluck MA, et al. Effect of the putative lithium mimetic ebselen on brain myo-inositol, sleep, and emotional processing in humans. Neuropsychopharmacology. 2016;41:1768–78.
    • (2016) Neuropsychopharmacology , vol.41 , pp. 1768-1778
    • Singh, N.1    Sharpley, A.L.2    Emir, U.E.3    Masaki, C.4    Herzallah, M.M.5    Gluck, M.A.6
  • 78
    • 85068626490 scopus 로고    scopus 로고
    • Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder
    • Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, et al. Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Mol Psychiatry. 2015:1–8.
    • (2015) Mol Psychiatry , pp. 1-8
    • Song, J.1    Bergen, S.E.2    Di Florio, A.3    Karlsson, R.4    Charney, A.5    Ruderfer, D.M.6
  • 79
    • 84866113546 scopus 로고    scopus 로고
    • Selective G2/M arrest in a p53Val135-transformed cell line induced by lithium is mediated through an intricate network of MAPK and β-catenin signaling pathways
    • COI: 1:CAS:528:DC%2BC38Xht1GksLzO, PID: 22884810
    • Tsui MMK, Tai WCS, Wong WY, Hsiao WLW. Selective G2/M arrest in a p53Val135-transformed cell line induced by lithium is mediated through an intricate network of MAPK and β-catenin signaling pathways. Life Sci. 2012;91:312–21.
    • (2012) Life Sci , vol.91 , pp. 312-321
    • Tsui, M.M.K.1    Tai, W.C.S.2    Wong, W.Y.3    Hsiao, W.L.W.4
  • 81
    • 84893969227 scopus 로고    scopus 로고
    • Effect of ions of potassium and lithium on NO synthase expression in the human adrenal cortex
    • COI: 1:CAS:528:DC%2BC2cXhtF2nsb0%3D, PID: 24771369
    • Kovzun EI, Lukashenya OS, Pushkarev VM, Mikosha AS, Tron’ko ND. Effect of ions of potassium and lithium on NO synthase expression in the human adrenal cortex. Bull Exp Biol Med. 2014;156:332–4.
    • (2014) Bull Exp Biol Med , vol.156 , pp. 332-334
    • Kovzun, E.I.1    Lukashenya, O.S.2    Pushkarev, V.M.3    Mikosha, A.S.4    Tron’ko, N.D.5
  • 82
    • 0033561306 scopus 로고    scopus 로고
    • Patterns of DST positivity in remitted affective disorders
    • COI: 1:STN:280:DyaK1Mzhtl2lsQ%3D%3D, PID: 10386185
    • Deshauer D, Grof E, Alda M, Grof P. Patterns of DST positivity in remitted affective disorders. Biol Psychiatry. 1999;45:1023–9.
    • (1999) Biol Psychiatry , vol.45 , pp. 1023-1029
    • Deshauer, D.1    Grof, E.2    Alda, M.3    Grof, P.4
  • 83
    • 84941951411 scopus 로고    scopus 로고
    • Decreased levels of canonical transient receptor potential channel 3 protein in the rat cerebral cortex after chronic treatment with lithium or valproate
    • Zaeri S, Farjadian S, Emamghoreishi M. Decreased levels of canonical transient receptor potential channel 3 protein in the rat cerebral cortex after chronic treatment with lithium or valproate. Res Pharm Sci. 2015;10:397–406.
    • (2015) Res Pharm Sci , vol.10 , pp. 397-406
    • Zaeri, S.1    Farjadian, S.2    Emamghoreishi, M.3
  • 84
    • 84945580719 scopus 로고    scopus 로고
    • Calcium channel genes associated with bipolar disorder modulate lithium’s amplification of circadian rhythms
    • PID: 26476274
    • McCarthy MJ, Le Roux MJ, Wei H, Beesley S, Kelsoe JR, Welsh DK. Calcium channel genes associated with bipolar disorder modulate lithium’s amplification of circadian rhythms. Neuropharmacology. 2015;101:439–48.
    • (2015) Neuropharmacology , vol.101 , pp. 439-448
    • McCarthy, M.J.1    Le Roux, M.J.2    Wei, H.3    Beesley, S.4    Kelsoe, J.R.5    Welsh, D.K.6
  • 85
    • 84867615226 scopus 로고    scopus 로고
    • Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP–implications for CREB-dependent gene transcription
    • COI: 1:CAS:528:DC%2BC38Xhslaku7zE, PID: 23000340
    • Heinrich A, von der Heyde AS, Böer U, Phu DT, Tzvetkov M, Oetjen E. Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP–implications for CREB-dependent gene transcription. Cell Signal. 2013;25:113–25.
    • (2013) Cell Signal , vol.25 , pp. 113-125
    • Heinrich, A.1    von der Heyde, A.S.2    Böer, U.3    Phu, D.T.4    Tzvetkov, M.5    Oetjen, E.6
  • 86
    • 84895886170 scopus 로고    scopus 로고
    • Effects of lithium and aripiprazole on brain stimulation reward and neuroplasticity markers in the limbic forebrain
    • COI: 1:CAS:528:DC%2BC3sXhvVKgt7jL, PID: 24275700
    • Mavrikaki M, Schintu N, Kastellakis A, Nomikos GG, Svenningsson P, Panagis G. Effects of lithium and aripiprazole on brain stimulation reward and neuroplasticity markers in the limbic forebrain. Eur Neuropsychopharmacol. 2014;24:630–8.
    • (2014) Eur Neuropsychopharmacol , vol.24 , pp. 630-638
    • Mavrikaki, M.1    Schintu, N.2    Kastellakis, A.3    Nomikos, G.G.4    Svenningsson, P.5    Panagis, G.6
  • 87
    • 84897106862 scopus 로고    scopus 로고
    • Alterations in phosphorylated cAMP response element-binding protein (pCREB) signaling: an endophenotype of lithium-responsive bipolar disorder?
    • COI: 1:CAS:528:DC%2BC3sXhvVyjsLjL, PID: 24238631
    • Alda M, Shao L, Wang J-F, Lopez de Lara C, Jaitovich-Groisman I, Lebel V, et al. Alterations in phosphorylated cAMP response element-binding protein (pCREB) signaling: an endophenotype of lithium-responsive bipolar disorder? Bipolar Disord. 2013;15:824–31.
    • (2013) Bipolar Disord , vol.15 , pp. 824-831
    • Alda, M.1    Shao, L.2    Wang, J.-F.3    Lopez de Lara, C.4    Jaitovich-Groisman, I.5    Lebel, V.6
  • 88
    • 84893798095 scopus 로고    scopus 로고
    • Basic presynaptic functions in hippocampal neurons are not affected by acute or chronic lithium treatment
    • COI: 1:CAS:528:DC%2BC3sXhsV2js7zP, PID: 24036894
    • Lueke K, Kaiser T, Svetlitchny A, Welzel O, Wenzel EM, Tyagarajan S, et al. Basic presynaptic functions in hippocampal neurons are not affected by acute or chronic lithium treatment. J Neural Transm. 2014;121:211–9.
    • (2014) J Neural Transm. , vol.121 , pp. 211-219
    • Lueke, K.1    Kaiser, T.2    Svetlitchny, A.3    Welzel, O.4    Wenzel, E.M.5    Tyagarajan, S.6
  • 89
    • 84857571570 scopus 로고    scopus 로고
    • Synapsin II is involved in the molecular pathway of lithium treatment in bipolar disorder
    • Cruceanu C, Alda M, Grof P, Rouleau GA, Turecki G. Synapsin II is involved in the molecular pathway of lithium treatment in bipolar disorder. PLoS One. 2012;7:e32680.
    • (2012) PLoS One , vol.e32680 , pp. 7
    • Cruceanu, C.1    Alda, M.2    Grof, P.3    Rouleau, G.A.4    Turecki, G.5
  • 90
    • 84939180231 scopus 로고    scopus 로고
    • Modifications of excitatory and inhibitory transmission in rat hippocampal pyramidal neurons by acute lithium treatment
    • COI: 1:CAS:528:DC%2BC2MXhtlWlt7jE, PID: 26247839
    • Wakita M, Nagami H, Takase Y, Nakanishi R, Kotani N, Akaike N. Modifications of excitatory and inhibitory transmission in rat hippocampal pyramidal neurons by acute lithium treatment. Brain Res Bull. 2015;117:39–44.
    • (2015) Brain Res Bull , vol.117 , pp. 39-44
    • Wakita, M.1    Nagami, H.2    Takase, Y.3    Nakanishi, R.4    Kotani, N.5    Akaike, N.6
  • 91
    • 84945578611 scopus 로고    scopus 로고
    • A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis
    • COI: 1:CAS:528:DC%2BC2MXhslSrurjK, PID: 26343379
    • Higgins GA, Allyn-Feuer A, Barbour E, Athey BD. A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis. Pharmacogenomics. 2015;16:1547–63.
    • (2015) Pharmacogenomics. , vol.16 , pp. 1547-1563
    • Higgins, G.A.1    Allyn-Feuer, A.2    Barbour, E.3    Athey, B.D.4
  • 92
    • 84939199013 scopus 로고    scopus 로고
    • Zanetti MV, Otaduy MC, de Sousa RT, Gattaz WF, Busatto GF, Leite CC, et al. Bimodal effect of lithium plasma levels on hippocampal glutamate concentrations in bipolar II depression: a pilot study. Int J Neuropsychopharmacol. 2015;18:pyu058–8
    • Zanetti MV, Otaduy MC, de Sousa RT, Gattaz WF, Busatto GF, Leite CC, et al. Bimodal effect of lithium plasma levels on hippocampal glutamate concentrations in bipolar II depression: a pilot study. Int J Neuropsychopharmacol. 2015;18:pyu058–8.
  • 93
    • 79959792795 scopus 로고    scopus 로고
    • The NMDA receptor/nitric oxide pathway: a target for the therapeutic and toxic effects of lithium
    • COI: 1:CAS:528:DC%2BC3MXotl2hs7o%3D, PID: 21492946
    • Ghasemi M, Dehpour AR. The NMDA receptor/nitric oxide pathway: a target for the therapeutic and toxic effects of lithium. Trends Pharmacol Sci. 2011;32:420–34.
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 420-434
    • Ghasemi, M.1    Dehpour, A.R.2
  • 94
    • 84892604542 scopus 로고    scopus 로고
    • Variant GADL1 and response to lithium therapy in bipolar I disorder
    • COI: 1:CAS:528:DC%2BC2cXotlKrsA%3D%3D, PID: 24369049
    • Chen C-H, Lee C-S, Lee M-TM, Ouyang W-C, Chen C-C, Chong M-Y, et al. Variant GADL1 and response to lithium therapy in bipolar I disorder. N Engl J Med. 2014;370:119–28.
    • (2014) N Engl J Med , vol.370 , pp. 119-128
    • Chen, C.-H.1    Lee, C.-S.2    Lee, M.-T.M.3    Ouyang, W.-C.4    Chen, C.-C.5    Chong, M.-Y.6
  • 95
    • 84961211119 scopus 로고    scopus 로고
    • Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study
    • COI: 1:CAS:528:DC%2BC28XhsVKntLg%3D, PID: 26806518
    • Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, et al. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet. 2016;387:1085–93.
    • (2016) Lancet , vol.387 , pp. 1085-1093
    • Hou, L.1    Heilbronner, U.2    Degenhardt, F.3    Adli, M.4    Akiyama, K.5    Akula, N.6
  • 96
    • 84899802026 scopus 로고    scopus 로고
    • Variant GADL1 and response to lithium in bipolar I disorder
    • COI: 1:CAS:528:DC%2BC2cXot12jur4%3D, PID: 24806173
    • Birnbaum R, Shin JH. Variant GADL1 and response to lithium in bipolar I disorder. N Engl J Med. 2014;370:1855–60.
    • (2014) N Engl J Med , vol.370 , pp. 1855-1860
    • Birnbaum, R.1    Shin, J.H.2
  • 97
    • 84856503248 scopus 로고    scopus 로고
    • Lithium attenuates methamphetamine-induced hyperlocomotion and behavioral sensitization via modulation of prefrontal monoamine release
    • COI: 1:CAS:528:DC%2BC38XhsFChu7k%3D, PID: 22001792
    • Ago Y, Tanaka T, Kita Y, Tokumoto H, Takuma K, Matsuda T. Lithium attenuates methamphetamine-induced hyperlocomotion and behavioral sensitization via modulation of prefrontal monoamine release. Neuropharmacology. 2012;62:1634–9.
    • (2012) Neuropharmacology , vol.62 , pp. 1634-1639
    • Ago, Y.1    Tanaka, T.2    Kita, Y.3    Tokumoto, H.4    Takuma, K.5    Matsuda, T.6
  • 98
    • 84939236572 scopus 로고    scopus 로고
    • Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: chronic lithium treats most, but not all features
    • PID: 26141192
    • van Enkhuizen J, Milienne-Petiot M, Geyer MA, Young JW. Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: chronic lithium treats most, but not all features. Psychopharmacology. 2015;232:3455–67.
    • (2015) Psychopharmacology , vol.232 , pp. 3455-3467
    • van Enkhuizen, J.1    Milienne-Petiot, M.2    Geyer, M.A.3    Young, J.W.4
  • 99
    • 84880554268 scopus 로고    scopus 로고
    • Anti-anhedonic activity of long-term lithium treatment in rats exposed to repeated unavoidable stress
    • COI: 1:CAS:528:DC%2BC3sXhtVOrs7nO, PID: 23363811
    • Marchese G, Scheggi S, Secci ME, De Montis MG, Gambarana C. Anti-anhedonic activity of long-term lithium treatment in rats exposed to repeated unavoidable stress. Int J Neuropsychopharmacol. 2013;16:1611–21.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 1611-1621
    • Marchese, G.1    Scheggi, S.2    Secci, M.E.3    De Montis, M.G.4    Gambarana, C.5
  • 100
    • 84945308820 scopus 로고    scopus 로고
    • Selective disruption of dopamine D2-receptors/beta-arrestin2 signaling by mood stabilizers
    • Del’ Guidice T, Beaulieu J-M. Selective disruption of dopamine D2-receptors/beta-arrestin2 signaling by mood stabilizers. J Recept Signal Transduct Res. 2015;35:224–32.
    • (2015) J Recept Signal Transduct Res , vol.35 , pp. 224-232
    • Del’ Guidice, T.1    Beaulieu, J.-M.2
  • 101
    • 84954026684 scopus 로고    scopus 로고
    • The aversive agent lithium chloride suppresses phasic dopamine release through central GLP-1 receptors
    • COI: 1:CAS:528:DC%2BC2MXhtlKntrvJ, PID: 26211731
    • Fortin SM, Chartoff EH, Roitman MF. The aversive agent lithium chloride suppresses phasic dopamine release through central GLP-1 receptors. Neuropsychopharmacology. 2016;41:906–15.
    • (2016) Neuropsychopharmacology. , vol.41 , pp. 906-915
    • Fortin, S.M.1    Chartoff, E.H.2    Roitman, M.F.3
  • 103
    • 84908178866 scopus 로고    scopus 로고
    • Glycine transporters GlyT1 and GlyT2 are differentially modulated by glycogen synthase kinase 3β
    • PID: 25301276
    • Jiménez E, Núñez E, Ibáñez I, Zafra F, Aragón C, Giménez C. Glycine transporters GlyT1 and GlyT2 are differentially modulated by glycogen synthase kinase 3β. Neuropharmacology. 2015;89:245–54.
    • (2015) Neuropharmacology , vol.89 , pp. 245-254
    • Jiménez, E.1    Núñez, E.2    Ibáñez, I.3    Zafra, F.4    Aragón, C.5    Giménez, C.6
  • 104
    • 84886609062 scopus 로고    scopus 로고
    • Genetic and clinical factors predict lithium’s effects on PER2 gene expression rhythms in cells from bipolar disorder patients
    • COI: 1:CAS:528:DC%2BC3sXhs1yitL3N, PID: 24150227
    • McCarthy MJ, Wei H, Marnoy Z, Darvish RM, McPhie DL, Cohen BM, et al. Genetic and clinical factors predict lithium’s effects on PER2 gene expression rhythms in cells from bipolar disorder patients. Transl Psychiatry. 2013;3:e318.
    • (2013) Transl Psychiatry. , vol.3
    • McCarthy, M.J.1    Wei, H.2    Marnoy, Z.3    Darvish, R.M.4    McPhie, D.L.5    Cohen, B.M.6
  • 105
    • 84857499458 scopus 로고    scopus 로고
    • A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response
    • McCarthy MJ, Nievergelt CM, Kelsoe JR, Welsh DK. A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response. PLoS One. 2012;7:e32091.
    • (2012) PLoS One , vol.e32091 , pp. 7
    • McCarthy, M.J.1    Nievergelt, C.M.2    Kelsoe, J.R.3    Welsh, D.K.4
  • 106
    • 84945474296 scopus 로고    scopus 로고
    • Mice lacking circadian clock components display different mood-related behaviors and do not respond uniformly to chronic lithium treatment
    • PID: 26317159
    • Schnell A, Sandrelli F, Ranc V, Ripperger JA, Brai E, Alberi L, et al. Mice lacking circadian clock components display different mood-related behaviors and do not respond uniformly to chronic lithium treatment. Chronobiol Int. 2015;32:1075–89.
    • (2015) Chronobiol Int , vol.32 , pp. 1075-1089
    • Schnell, A.1    Sandrelli, F.2    Ranc, V.3    Ripperger, J.A.4    Brai, E.5    Alberi, L.6
  • 107
    • 84979859189 scopus 로고    scopus 로고
    • Lithium-induced clock gene expression in lymphoblastoid cells of bipolar affective patients
    • COI: 1:CAS:528:DC%2BC2MXhtFyhsL%2FL, PID: 26011568
    • Kittel-Schneider S, Schreck S, Ziegler C, Weißflog L, Hilscher M, Schwarz R, et al. Lithium-induced clock gene expression in lymphoblastoid cells of bipolar affective patients. Pharmacopsychiatry. 2015;48:145–9.
    • (2015) Pharmacopsychiatry. , vol.48 , pp. 145-149
    • Kittel-Schneider, S.1    Schreck, S.2    Ziegler, C.3    Weißflog, L.4    Hilscher, M.5    Schwarz, R.6
  • 108
    • 84896708285 scopus 로고    scopus 로고
    • Polymorphism of circadian clock genes and prophylactic lithium response
    • COI: 1:CAS:528:DC%2BC2cXktVyltbk%3D, PID: 24636202
    • Rybakowski JK, Dmitrzak-Weglar M, Kliwicki S, Hauser J. Polymorphism of circadian clock genes and prophylactic lithium response. Bipolar Disord. 2014;16:151–8.
    • (2014) Bipolar Disord , vol.16 , pp. 151-158
    • Rybakowski, J.K.1    Dmitrzak-Weglar, M.2    Kliwicki, S.3    Hauser, J.4
  • 110
    • 84875166630 scopus 로고    scopus 로고
    • The ANK3 bipolar disorder gene regulates psychiatric-related behaviors that are modulated by lithium and stress
    • COI: 1:CAS:528:DC%2BC38XhvVais7rO, PID: 23237312
    • Leussis MP, Berry-Scott EM, Saito M, Jhuang H, de Haan G, Alkan O, et al. The ANK3 bipolar disorder gene regulates psychiatric-related behaviors that are modulated by lithium and stress. Biol Psychiatry. 2013;73:683–90.
    • (2013) Biol Psychiatry , vol.73 , pp. 683-690
    • Leussis, M.P.1    Berry-Scott, E.M.2    Saito, M.3    Jhuang, H.4    de Haan, G.5    Alkan, O.6
  • 112
    • 84961820491 scopus 로고    scopus 로고
    • The Lithium Battery: assessing the neurocognitive profile of lithium in bipolar disorder
    • PID: 27004564
    • Malhi GS, McAulay C, Gershon S, Gessler D, Fritz K, Das P, et al. The Lithium Battery: assessing the neurocognitive profile of lithium in bipolar disorder. Bipolar Disord. 2016;18:102–15.
    • (2016) Bipolar Disord , vol.18 , pp. 102-115
    • Malhi, G.S.1    McAulay, C.2    Gershon, S.3    Gessler, D.4    Fritz, K.5    Das, P.6
  • 114
    • 84921468370 scopus 로고    scopus 로고
    • Effects of lithium on cortical thickness and hippocampal subfield volumes in psychotic bipolar disorder
    • COI: 1:STN:280:DC%2BC2MvktVWmsA%3D%3D, PID: 25563516
    • Giakoumatos CI, Nanda P, Mathew IT, Tandon N, Shah J, Bishop JR, et al. Effects of lithium on cortical thickness and hippocampal subfield volumes in psychotic bipolar disorder. J Psychiatr Res. 2015;61:180–7.
    • (2015) J Psychiatr Res , vol.61 , pp. 180-187
    • Giakoumatos, C.I.1    Nanda, P.2    Mathew, I.T.3    Tandon, N.4    Shah, J.5    Bishop, J.R.6
  • 115
    • 84938904022 scopus 로고    scopus 로고
    • Lithium treatment and hippocampal subfields and amygdala volumes in bipolar disorder
    • COI: 1:CAS:528:DC%2BC2MXht1yrsLjJ, PID: 25809287
    • Hartberg CB, Jørgensen KN, Haukvik UK, Westlye LT, Melle I, Andreassen OA, et al. Lithium treatment and hippocampal subfields and amygdala volumes in bipolar disorder. Bipolar Disord. 2015;17:496–506.
    • (2015) Bipolar Disord , vol.17 , pp. 496-506
    • Hartberg, C.B.1    Jørgensen, K.N.2    Haukvik, U.K.3    Westlye, L.T.4    Melle, I.5    Andreassen, O.A.6
  • 116
    • 84858280303 scopus 로고    scopus 로고
    • Increased hippocampal volumes in lithium treated adolescents with bipolar disorders: a structural MRI study
    • COI: 1:CAS:528:DC%2BC38Xjs1agt7s%3D, PID: 22325693
    • Baykara B, Inal-Emiroglu N, Karabay N, Çakmakçı H, Cevher N, Şentürk Pilan B, et al. Increased hippocampal volumes in lithium treated adolescents with bipolar disorders: a structural MRI study. J Affect Disord. 2012;138:433–9.
    • (2012) J Affect Disord , vol.138 , pp. 433-439
    • Baykara, B.1    Inal-Emiroglu, N.2    Karabay, N.3    Çakmakçı, H.4    Cevher, N.5    Şentürk Pilan, B.6
  • 117
    • 84882838488 scopus 로고    scopus 로고
    • A longitudinal study of fronto-limbic brain structures in patients with bipolar I disorder during lithium treatment
    • COI: 1:CAS:528:DC%2BC3sXpt1ClsLk%3D, PID: 23764385
    • Selek S, Nicoletti M, Zunta-Soares GB, Hatch JP, Nery FG, Matsuo K, et al. A longitudinal study of fronto-limbic brain structures in patients with bipolar I disorder during lithium treatment. J Affect Disord. 2013;150:629–33.
    • (2013) J Affect Disord , vol.150 , pp. 629-633
    • Selek, S.1    Nicoletti, M.2    Zunta-Soares, G.B.3    Hatch, J.P.4    Nery, F.G.5    Matsuo, K.6
  • 118
    • 84863404151 scopus 로고    scopus 로고
    • Contrasting effects of haloperidol and lithium on rodent brain structure: a magnetic resonance imaging study with postmortem confirmation
    • COI: 1:CAS:528:DC%2BC38XlvFKgs7o%3D, PID: 22244831
    • Vernon AC, Natesan S, Crum WR, Cooper JD, Modo M, Williams SCR, et al. Contrasting effects of haloperidol and lithium on rodent brain structure: a magnetic resonance imaging study with postmortem confirmation. Biol Psychiatry. 2012;71:855–63.
    • (2012) Biol Psychiatry , vol.71 , pp. 855-863
    • Vernon, A.C.1    Natesan, S.2    Crum, W.R.3    Cooper, J.D.4    Modo, M.5    Williams, S.C.R.6
  • 119
    • 84925510733 scopus 로고    scopus 로고
    • Lithium and GSK-3β promoter gene variants influence cortical gray matter volumes in bipolar disorder
    • Benedetti F, Poletti S, Radaelli D, Locatelli C, Pirovano A, Lorenzi C, et al. Lithium and GSK-3β promoter gene variants influence cortical gray matter volumes in bipolar disorder. Psychopharmacology. 2015;232:1325–36.
    • (2015) Psychopharmacology , vol.232 , pp. 1325-1336
    • Benedetti, F.1    Poletti, S.2    Radaelli, D.3    Locatelli, C.4    Pirovano, A.5    Lorenzi, C.6
  • 120
    • 84945197931 scopus 로고    scopus 로고
    • Prophylactic lithium treatment and cognitive performance in patients with a long history of bipolar illness: no simple answers in complex disease-treatment interplay
    • PID: 25540718
    • Pfennig A, Alda M, Young T, MacQueen G, Rybakowski J, Suwalska A, et al. Prophylactic lithium treatment and cognitive performance in patients with a long history of bipolar illness: no simple answers in complex disease-treatment interplay. Int J Bipolar Disord. 2014;2:1.
    • (2014) Int J Bipolar Disord. , vol.2 , pp. 1
    • Pfennig, A.1    Alda, M.2    Young, T.3    MacQueen, G.4    Rybakowski, J.5    Suwalska, A.6
  • 121
    • 84860375509 scopus 로고    scopus 로고
    • Hippocampal volumes in bipolar disorders: opposing effects of illness burden and lithium treatment
    • PID: 22548899
    • Hajek T, Cullis J, Novak T, Kopecek M, Hoschl C, Blagdon R, et al. Hippocampal volumes in bipolar disorders: opposing effects of illness burden and lithium treatment. Bipolar Disord. 2012;14:261–70.
    • (2012) Bipolar Disord , vol.14 , pp. 261-270
    • Hajek, T.1    Cullis, J.2    Novak, T.3    Kopecek, M.4    Hoschl, C.5    Blagdon, R.6
  • 122
    • 84856618060 scopus 로고    scopus 로고
    • Neuroprotective effects of low-dose lithium in individuals at ultra-high risk for psychosis. A longitudinal MRI/MRS study
    • COI: 1:CAS:528:DC%2BC38XjtV2gtrs%3D, PID: 22239590
    • Berger GE, Wood SJ, Ross M, Hamer CA, Wellard RM, Pell G, et al. Neuroprotective effects of low-dose lithium in individuals at ultra-high risk for psychosis. A longitudinal MRI/MRS study. Curr Pharm Des. 2012;18:570–5.
    • (2012) Curr Pharm Des , vol.18 , pp. 570-575
    • Berger, G.E.1    Wood, S.J.2    Ross, M.3    Hamer, C.A.4    Wellard, R.M.5    Pell, G.6
  • 125
    • 70350172912 scopus 로고    scopus 로고
    • Validating GSK3 as an in vivo target of lithium action
    • PID: 19754466
    • O’Brien WT, Klein PS. Validating GSK3 as an in vivo target of lithium action. Biochem Soc Trans. 2009;37:1133–8.
    • (2009) Biochem Soc Trans , vol.37 , pp. 1133-1138
    • O’Brien, W.T.1    Klein, P.S.2
  • 126
    • 84930230942 scopus 로고    scopus 로고
    • Wei YB, Backlund L, Wegener G, Mathé AA, Lavebratt C. Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium. Int J Neuropsychopharmacol. 2015;18:pyv002
    • Wei YB, Backlund L, Wegener G, Mathé AA, Lavebratt C. Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium. Int J Neuropsychopharmacol. 2015;18:pyv002.
  • 127
    • 84937814689 scopus 로고    scopus 로고
    • Calcium-dependent intracellular signal pathways in primary cultured adipocytes and ANK3 gene variation in patients with bipolar disorder and healthy controls
    • COI: 1:CAS:528:DC%2BC2cXhslOjsbvO, PID: 25311363
    • Hayashi A, Le Gal K, Södersten K, Vizlin-Hodzic D, Ågren H, Funa K. Calcium-dependent intracellular signal pathways in primary cultured adipocytes and ANK3 gene variation in patients with bipolar disorder and healthy controls. Mol Psychiatry. 2015;20:931–40.
    • (2015) Mol Psychiatry. , vol.20 , pp. 931-940
    • Hayashi, A.1    Le Gal, K.2    Södersten, K.3    Vizlin-Hodzic, D.4    Ågren, H.5    Funa, K.6
  • 129
    • 84929944337 scopus 로고    scopus 로고
    • Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities
    • COI: 1:CAS:528:DC%2BC2MXjvFWks74%3D, PID: 25733313
    • Madison JM, Zhou F, Nigam A, Hussain A, Barker DD, Nehme R, et al. Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities. Mol Psychiatry. 2015;20:703–17.
    • (2015) Mol Psychiatry. , vol.20 , pp. 703-717
    • Madison, J.M.1    Zhou, F.2    Nigam, A.3    Hussain, A.4    Barker, D.D.5    Nehme, R.6
  • 130
    • 84946239187 scopus 로고    scopus 로고
    • Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
    • COI: 1:CAS:528:DC%2BC2MXhslynurrL, PID: 26524527
    • Mertens J, Wang Q-W, Kim Y, Yu DX, Pham S, Yang B, et al. Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. 2015;527:95–9.
    • (2015) Nature , vol.527 , pp. 95-99
    • Mertens, J.1    Wang, Q.-W.2    Kim, Y.3    Yu, D.X.4    Pham, S.5    Yang, B.6
  • 131
    • 84958766188 scopus 로고    scopus 로고
    • Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla
    • Masaki C, Sharpley AL, Godlewska BR, Berrington A, Hashimoto T, Singh N, et al. Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla. Psychopharmacology. 2016;233:1–8.
    • (2016) Psychopharmacology , vol.233 , pp. 1-8
    • Masaki, C.1    Sharpley, A.L.2    Godlewska, B.R.3    Berrington, A.4    Hashimoto, T.5    Singh, N.6
  • 134
    • 84857357845 scopus 로고    scopus 로고
    • Gene-gene interaction of glycogen synthase kinase 3-β and serotonin transporter on human antidepressant response to sleep deprivation
    • COI: 1:CAS:528:DC%2BC38XisFWmtrw%3D, PID: 22119086
    • Benedetti F, Dallaspezia S, Lorenzi C, Pirovano A, Radaelli D, Locatelli C, et al. Gene-gene interaction of glycogen synthase kinase 3-β and serotonin transporter on human antidepressant response to sleep deprivation. J Affect Disord. 2012;136:514–9.
    • (2012) J Affect Disord , vol.136 , pp. 514-519
    • Benedetti, F.1    Dallaspezia, S.2    Lorenzi, C.3    Pirovano, A.4    Radaelli, D.5    Locatelli, C.6
  • 135
    • 84874950492 scopus 로고    scopus 로고
    • Study of the association of serotonin transporter triallelic 5-HTTLPR and STin2 VNTR polymorphisms with lithium prophylaxis response in bipolar disorder
    • COI: 1:CAS:528:DC%2BC3sXltFCht78%3D, PID: 23277128
    • Tharoor H, Kotambail A, Jain S, Sharma PSVN, Satyamoorthy K. Study of the association of serotonin transporter triallelic 5-HTTLPR and STin2 VNTR polymorphisms with lithium prophylaxis response in bipolar disorder. Psychiatr Genet. 2013;23:77–81.
    • (2013) Psychiatr Genet , vol.23 , pp. 77-81
    • Tharoor, H.1    Kotambail, A.2    Jain, S.3    Sharma, P.S.V.N.4    Satyamoorthy, K.5
  • 136
    • 84925456444 scopus 로고    scopus 로고
    • White matter microstructure in bipolar disorder is influenced by the serotonin transporter gene polymorphism 5-HTTLPR
    • COI: 1:CAS:528:DC%2BC2MXlsVKju78%3D, PID: 25704032
    • Benedetti F, Bollettini I, Poletti S, Locatelli C, Lorenzi C, Pirovano A, et al. White matter microstructure in bipolar disorder is influenced by the serotonin transporter gene polymorphism 5-HTTLPR. Genes Brain Behav. 2015;14:238–50.
    • (2015) Genes Brain Behav. , vol.14 , pp. 238-250
    • Benedetti, F.1    Bollettini, I.2    Poletti, S.3    Locatelli, C.4    Lorenzi, C.5    Pirovano, A.6
  • 137
    • 84941284374 scopus 로고    scopus 로고
    • Exploring genetic variability at PI, GSK3, HPA, and glutamatergic pathways in lithium response: association with IMPA2, INPP1, and GSK3B genes
    • COI: 1:CAS:528:DC%2BC2MXhsVeqsbbO, PID: 26267417
    • Mitjans M, Arias B, Jiménez E, Goikolea JM, Sáiz PA, García-Portilla MP, et al. Exploring genetic variability at PI, GSK3, HPA, and glutamatergic pathways in lithium response: association with IMPA2, INPP1, and GSK3B genes. J Clin Psychopharmacol. 2015;35:600–4.
    • (2015) J Clin Psychopharmacol , vol.35 , pp. 600-604
    • Mitjans, M.1    Arias, B.2    Jiménez, E.3    Goikolea, J.M.4    Sáiz, P.A.5    García-Portilla, M.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.