The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Liechti, Fabian D ^a   Studle, Nicolas ^a   Theurillat, Regula ^a   Grandgirard, Denis ^a   Thormann, Wolfgang ^a   Leib, Stephen L ^a,b  

^a UNIVERSITY OF BERN   (Switzerland)

^b SPIEZ LABORATORY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 10; LITHIUM CHLORIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR; CCL2 PROTEIN, RAT; NEUROPROTECTIVE AGENT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BAX GENE; BCL 2 GENE; BDNF GENE; BRAIN INJURY; BRAIN TISSUE; CAPILLARY ELECTROPHORESIS; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG EFFECT; GENE EXPRESSION; HIPPOCAMPUS; INFANT; MENINGITIS; MORPHOMETRICS; MORRIS WATER MAZE TEST; NERVE REGENERATION; NEUROPROTECTION; NISSL SUBSTANCE; NONHUMAN; PNEUMOCOCCAL MENINGITIS; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SPATIAL MEMORY; STREPTOCOCCUS PNEUMONIAE; TP53 GENE; ANIMAL; BLOOD; BRAIN; CEREBROSPINAL FLUID; CYTOLOGY; DISEASE MODEL; DOWN REGULATION; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; GENETICS; MENINGITIS, PNEUMOCOCCAL; METABOLISM; PATHOGENICITY; PATHOLOGY; UPREGULATION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN; CHEMOKINE CCL2; DENTATE GYRUS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; INTERLEUKIN-10; LITHIUM CHLORIDE; MENINGITIS, PNEUMOCOCCAL; MICROSCOPY, FLUORESCENCE; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SPATIAL MEMORY; STREPTOCOCCUS PNEUMONIAE; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84915748256     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113607     Document Type: Article

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