Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: Chronic lithium treats most, but not all features

Psychopharmacology

Volumn 232, Issue 18, 2015, Pages 3455-3467

  Van Enkhuizen, Jordy ^a,b   Milienne Petiot, Morgane ^a,b   Geyer, Mark A ^a,c   Young, Jared W ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UTRECHT UNIVERSITY   (Netherlands)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Acetylcholine; Bipolar disorder; Depression; Dopamine transporter; Lithium; Mania; Prepulse inhibition

Indexed keywords

ACETYLCHOLINE; DOPAMINE; LITHIUM; PHYSOSTIGMINE; VANOXERINE; CHOLINESTERASE INHIBITOR; DOPAMINE UPTAKE INHIBITOR; LITHIUM DERIVATIVE; PIPERAZINE DERIVATIVE; TRANQUILIZER;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; DEPRESSION; DRUG EFFICACY; DRUG RESPONSE; EXPLORATORY BEHAVIOR; FEMALE; FORCED SWIM TEST; LOCOMOTION; MALE; MANIA; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; SENSORY GATING; TAIL SUSPENSION TEST; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; IMMOBILIZATION; MOUSE; SWIMMING;

ACETYLCHOLINE; ANIMALS; ANTIMANIC AGENTS; BEHAVIOR, ANIMAL; BIPOLAR DISORDER; CHOLINESTERASE INHIBITORS; DEPRESSION; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; EXPLORATORY BEHAVIOR; FEMALE; HINDLIMB SUSPENSION; LITHIUM COMPOUNDS; MALE; MICE; MICE, INBRED C57BL; PHYSOSTIGMINE; PIPERAZINES; PREPULSE INHIBITION; SENSORY GATING; SWIMMING;

EID: 84939236572     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-015-4000-4     Document Type: Article

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