Gene-gene interaction of glycogen synthase kinase 3-β and serotonin transporter on human antidepressant response to sleep deprivation

Journal of Affective Disorders

Volumn 136, Issue 3, 2012, Pages 514-519

  Benedetti, Francesco ^a   Dallaspezia, Sara ^a   Lorenzi, Cristina ^a   Pirovano, Adele ^a   Radaelli, Daniele ^a   Locatelli, Clara ^a   Poletti, Sara ^a   Colombo, Cristina ^a   Smeraldi, Enrico ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

Antidepressant; Bipolar disorder; Glycogen synthase kinase 3 ; Serotonin promoter; Sleep deprivation

Indexed keywords

ANTIDEPRESSANT AGENT; GLYCOGEN SYNTHASE KINASE 3BETA; SEROTONIN TRANSPORTER;

ADULT; ARTICLE; BIPOLAR DEPRESSION; DISEASE SEVERITY; DRUG RESPONSE; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MONTGOMERY ASBERG DEPRESSION RATING SCALE; MOOD; PHARMACOGENETICS; PRIORITY JOURNAL; PROMOTER REGION; SELF EVALUATION; SLEEP DEPRIVATION; TRANSLATIONAL RESEARCH; VISUAL ANALOG SCALE;

ADULT; ANTIDEPRESSIVE AGENTS; BIPOLAR DISORDER; DEPRESSIVE DISORDER, MAJOR; FEMALE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SLEEP DEPRIVATION;

EID: 84857357845     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2011.10.039     Document Type: Article

References (42)

1. M. Adli, D.L. Hollinde, T. Stamm, K. Wiethoff, M. Tsahuridu, J. Kirchheiner, A. Heinz, and M. Bauer Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta - 50 T/C single nucleotide polymorphism Biological Psychiatry 62 2007 1295 1302
2. B. Arias, R. Catalan, C. Gasto, B. Gutierrez, and L. Fananas 5-HTTLPR polymorphism of the serotonin transporter gene predicts non-remission in major depression patients treated with citalopram in a 12-weeks follow up study Journal of Clinical Psychopharmacology 23 2003 563 567
3. J.M. Beaulieu, X. Zhang, R.M. Rodriguiz, T.D. Sotnikova, M.J. Cools, W.C. Wetsel, R.R. Gainetdinov, and M.G. Caron Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency Proceedings of the National Academy of Sciences of the United States of America 105 2008 1333 1338
4. J.M. Beaulieu, R.R. Gainetdinov, and M.G. Caron Akt/GSK3 signaling in the action of psychotropic drugs Annual Review of Pharmacology and Toxicology 49 2009 327 347
5. F. Benedetti, and E. Smeraldi Neuroimaging and genetics of antidepressant response to sleep deprivation: implications for drug development Current Pharmaceutical Design 15 2009 2637 2649
6. F. Benedetti, A. Serretti, C. Colombo, E. Campori, B. Barbini, D. Di Bella, and E. Smeraldi Influence of a functional polymorphism within the promoter of the serotonin transporter gene on the effects of total sleep deprivation in bipolar depression The American Journal of Psychiatry 156 1999 1450 1452
7. F. Benedetti, C. Colombo, A. Serretti, C. Lorenzi, A. Pontiggia, B. Barbini, and E. Smeraldi Antidepressant effects of light therapy combined with sleep deprivation are influenced by a functional polymorphism within the promoter of the serotonin transporter gene Biological Psychiatry 54 2003 687 692
8. F. Benedetti, A. Bernasconi, C. Lorenzi, A. Pontiggia, A. Serretti, C. Colombo, and E. Smeraldi A single nucleotide polymorphism in glycogen synthase kinase 3-beta promoter gene influences onset of illness in patients affected by bipolar disorder Neuroscience Letters 355 2004 37 40
9. F. Benedetti, A. Serretti, C. Colombo, C. Lorenzi, V. Tubazio, and E. Smeraldi A glycogen synthase kinase 3-beta promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression Neuroscience Letters 368 2004 123 126
10. F. Benedetti, A. Serretti, A. Pontiggia, A. Bernasconi, C. Lorenzi, C. Colombo, and E. Smeraldi Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-beta - 50 T/C SNP Neuroscience Letters 376 2005 51 55
11. F. Benedetti, A. Bernasconi, V. Blasi, M. Cadioli, C. Colombo, A. Falini, C. Lorenzi, D. Radaelli, G. Scotti, and E. Smeraldi Neural and genetic correlates of antidepressant response to sleep deprivation: a fMRI study of moral valence decision in bipolar depression Archives of General Psychiatry 64 2007 179 187
12. F. Benedetti, B. Barbini, A. Bernasconi, M.C. Fulgosi, E. Campori, C. Colombo, S. Dallaspezia, C. Lorenzi, A. Pontiggia, D. Radaelli, and E. Smeraldi Lithium overcomes the influence of 5-HTTLPR gene polymorphism on antidepressant response to sleep deprivation Journal of Clinical Psychopharmacology 28 2008 249 251
13. F. Benedetti, S. Poletti, D. Radaelli, A. Bernasconi, R. Cavallaro, A. Falini, C. Lorenzi, A. Pirovano, S. Dallaspezia, C. Locatelli, G. Scotti, and E. Smeraldi Temporal lobe grey matter volume in schizophrenia is associated with a genetic polymorphism influencing glycogen synthase kinase 3-beta activity Genes, Brain, and Behavior 9 2010 365 371
14. E. Beurel, L. Song, and R.S. Jope Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice Molecular Psychiatry 16 2011 1068 1070
15. L. Chen, W. Zhou, P.C. Chen, I. Gaisina, S. Yang, and X. Li Glycogen synthase kinase-3beta is a functional modulator of serotonin-1B receptors Molecular Pharmacology 79 2011 974 986
16. N. Diazgranados, L. Ibrahim, N.E. Brutsche, A. Newberg, P. Kronstein, S. Khalife, W.A. Kammerer, Z. Quezado, D.A. Luckenbaugh, G. Salvadore, R. Machado-Vieira, H.K. Manji, and C.A. Zarate Jr. A randomized add-on trial of an N-methyl-d-aspartate antagonist in treatment-resistant bipolar depression Archives of General Psychiatry 67 2010 793 802
17. L.K. Durham, S.M. Webb, P.M. Milos, C.M. Clary, and A.B. Seymour The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder Psychopharmacology 174 2004 525 529
18. D. Ebert, and M. Berger Neurobiological similarities in antidepressant sleep deprivation and psychostimulant use: a psychostimulant theory of antidepressant sleep deprivation Psychopharmacology 140 1998 1 10
19. J.E. Forde, and T.C. Dale Glycogen synthase kinase 3: a key regulator of cellular fate Cellular and Molecular Life Sciences 64 2007 1930 1944
20. T. Frodl, N. Koutsouleris, R. Bottlender, C. Born, M. Jager, M. Morgenthaler, J. Scheuerecker, P. Zill, T. Baghai, C. Schule, R. Rupprecht, B. Bondy, M. Reiser, H.J. Moller, and E.M. Meisenzahl Reduced gray matter brain volumes are associated with variants of the serotonin transporter gene in major depression Molecular Psychiatry 13 2008 1093 1101
21. J.C. Gillin, M. Buchsbaum, J. Wu, C. Clark, and W. Bunney Jr. Sleep deprivation as a model experimental antidepressant treatment: findings from functional brain imaging Depression and Anxiety 14 2001 37 49
22. T.D. Gould, and H.K. Manji Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs Neuropsychopharmacology 30 2005 1223 1237
23. C.A. Grimes, and R.S. Jope The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling Progress in Neurobiology 65 2001 391 426
24. T. Hill, and P. Lewicki Statistics: methods and applications A Comprehensive Reference for Science, Industry, and Data Mining General Linear Models 18 2006 StatSoft Tulsa (OK) Chapter 245 276
25. K. Inoki, H. Ouyang, T. Zhu, C. Lindvall, Y. Wang, X. Zhang, Q. Yang, C. Bennett, Y. Harada, K. Stankunas, C.Y. Wang, X. He, O.A. MacDougald, M. You, B.O. Williams, and K.L. Guan TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth Cell 126 2006 955 968
26. L. Kockeritz, B. Doble, S. Patel, and J.R. Woodgett Glycogen synthase kinase-3 - an overview of an over-achieving protein kinase Current Drug Targets 7 2006 1377 1388
27. J.H. Krystal N-methyl-d-aspartate glutamate receptor antagonists and the promise of rapid-acting antidepressants Archives of General Psychiatry 67 2010 1110 1111
28. J.B. Kwok, M. Hallupp, C.T. Loy, D.K. Chan, J. Woo, G.D. Mellick, D.D. Buchanan, P.A. Silburn, G.M. Halliday, and P.R. Schofield GSK3B polymorphisms alter transcription and splicing in Parkinson's disease Annals of Neurology 58 2005 829 839
29. K.P. Lesch, D. Bengel, A. Heils, S.Z. Sabol, B.D. Greenberg, S. Petri, J. Benjamin, C.R. Muller, D.H. Hamer, and D.L. Murphy Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1996 1527 1531
30. X. Li, and R.S. Jope Is glycogen synthase kinase-3 a central modulator in mood regulation? Neuropsychopharmacology 35 2010 2143 2154
31. N. Li, B. Lee, R.J. Liu, M. Banasr, J.M. Dwyer, M. Iwata, X.Y. Li, G. Aghajanian, and R.S. Duman mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists Science 329 2010 959 964
32. H.K. Manji, G.J. Moore, G. Rajkowska, and G. Chen Neuroplasticity and cellular resilience in mood disorders Molecular Psychiatry 5 2000 578 593
33. C.E. McCulloch, S.R. Searle, and J.M. Neuhaus Generalized, Linear, and Mixed Models Second Edition 2008 John Wiley & Sons
34. M.J. Millan Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application Pharmacology and Therapeutics 110 2006 135 370
35. B.G. Pollock, R.E. Ferrell, B.H. Mulsant, S. Mazumdar, M. Miller, R.A. Sweet, S. Davis, M.A. Kirshner, P.R. Houck, J.A. Stack, C.F. Reynolds, and D.J. Kupfer Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression Neuropsychopharmacology 23 2000 587 590
36. J.L. Rausch, M.E. Johnson, Y.J. Fei, J.Q. Li, N. Shendarkar, H.M. Hobby, V. Ganapathy, and F.H. Leibach Initial conditions of serotonin transporter kinetics and genotype: influence on SSRI treatment trial outcome Biological Psychiatry 51 2002 723 732
37. B.M. Ruf, and Z. Bhagwagar The 5-HT1B receptor: a novel target for the pathophysiology of depression Current Drug Targets 10 2009 1118 1138
38. E. Smeraldi, R. Zanardi, F. Benedetti, D. Dibella, J. Perez, and M. Catalano Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine Molecular Psychiatry 3 1998 508 511
39. E. Smeraldi, F. Benedetti, and R. Zanardi Serotonin transporter promoter genotype and illness recurrence in mood disorders European Neuropsychopharmacology 12 2002 73 75
40. N. Timm, and K. Kim Univariate and Multivariate General Linear Models: Theory and Applications with SAS Second Edition 2006 Springer Berlin/ Heidelberg
41. V.V. Vyazovskiy, C. Cirelli, M. Pfister-Genskow, U. Faraguna, and G. Tononi Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep Nature Neuroscience 11 2008 200 208
42. R. Zanardi, F. Benedetti, D. DiBella, M. Catalano, and E. Smeraldi Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of serotonin transporter gene Journal of Clinical Psychopharmacology 20 2000 105 107