A polymorphism associated with depressive disorders differentially regulates brain derived neurotrophic factor promoter IV activity

Biological Psychiatry

Volumn 71, Issue 7, 2012, Pages 618-626

  Hing, Benjamin ^a   Davidson, Scott ^a   Lear, Marrisa ^a   Breen, Gerome ^b   Quinn, John ^c   McGuffin, Peter ^b   MacKenzie, Alasdair ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

BDNF promoter IV; brain derived neurotrophic factor; cognitive deficit and mood disorder; neuronal depolarization; single nucleotide polymorphisms; tissue specific gene regulation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CIS ACTING ELEMENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; LITHIUM CHLORIDE; PHORBOL 13 ACETATE 12 MYRISTATE; POTASSIUM CHLORIDE; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR;

ALLELE; AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CELL POLARITY; COGNITIVE DEFECT; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DEPRESSION; ENZYME ACTIVITY; GENE ACTIVITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CONSERVATION; HIPPOCAMPUS; MOOD DISORDER; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; STIMULUS RESPONSE; UPREGULATION;

ALLELES; AMYGDALA; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL CORTEX; DEPRESSIVE DISORDER; FORSKOLIN; GENE EXPRESSION REGULATION; GENOMICS; HIPPOCAMPUS; HUMANS; LITHIUM CHLORIDE; MICE; MICE, TRANSGENIC; PHORBOL ESTERS; POLYMORPHISM, SINGLE NUCLEOTIDE; POTASSIUM CHLORIDE; PRIMARY CELL CULTURE; PROMOTER REGIONS, GENETIC; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84858246435     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.11.030     Document Type: Article

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