-
1
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
Amir RE, Van den Veyver IB, Wan M et al (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23:185-188
-
(1999)
Nat Genet
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van Den Veyver, I.B.2
Wan, M.3
-
2
-
-
84856479947
-
Gene-editing nucleases
-
Baker M (2012) Gene-editing nucleases. Nat Methods 9:23-26
-
(2012)
Nat Methods
, vol.9
, pp. 23-26
-
-
Baker, M.1
-
3
-
-
84861581164
-
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
-
Barbieri CE, Baca SC, Lawrence MS et al (2012) Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat Genet 44:685-689
-
(2012)
Nat Genet
, vol.44
, pp. 685-689
-
-
Barbieri, C.E.1
Baca, S.C.2
Lawrence, M.S.3
-
4
-
-
23744516021
-
Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2
-
Beffert U, Weeber EJ, Durudas A et al (2005) Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron 47:567-579
-
(2005)
Neuron
, vol.47
, pp. 567-579
-
-
Beffert, U.1
Weeber, E.J.2
Durudas, A.3
-
5
-
-
33746219660
-
The design of transcription-factor binding sites is affected by combinatorial regulation
-
Bilu Y, Barkai N (2005) The design of transcription-factor binding sites is affected by combinatorial regulation. Genome Biol 6:R103
-
(2005)
Genome Biol
, vol.6
-
-
Bilu, Y.1
Barkai, N.2
-
7
-
-
33746795976
-
DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA-TTC repeats in Friedreich’s ataxia
-
Burnett R, Melander C, Puckett JW et al (2006) DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA-TTC repeats in Friedreich’s ataxia. Proc Natl Acad Sci U S A 103:11497-11502
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 11497-11502
-
-
Burnett, R.1
Melander, C.2
Puckett, J.W.3
-
8
-
-
79953056443
-
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
-
Ceol CJ, Houvras Y, Jane-Valbuena J et al (2011) The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature 471:513-517
-
(2011)
Nature
, vol.471
, pp. 513-517
-
-
Ceol, C.J.1
Houvras, Y.2
Jane-Valbuena, J.3
-
9
-
-
84871952878
-
Pyrrole-Imidazole polyamides distinguish between double-helical DNA and RNA
-
Chenoweth DM, Meier JL, Dervan PB (2013) Pyrrole-Imidazole polyamides distinguish between double-helical DNA and RNA. Angew Chem Int Ed 52:415-418
-
(2013)
Angew Chem Int Ed
, vol.52
, pp. 415-418
-
-
Chenoweth, D.M.1
Meier, J.L.2
Dervan, P.B.3
-
10
-
-
0035339092
-
Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase
-
Chi Y, Huddleston MJ, Zhang X et al (2001) Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev 15:1078-1092
-
(2001)
Genes Dev
, vol.15
, pp. 1078-1092
-
-
Chi, Y.1
Huddleston, M.J.2
Zhang, X.3
-
11
-
-
77954701301
-
Why your DNA isn’t your destiny
-
Cloud J (2010) Why your DNA isn’t your destiny. Time Mag 61:175-189
-
(2010)
Time Mag
, vol.61
, pp. 175-189
-
-
Cloud, J.1
-
12
-
-
79953162883
-
Function and regulation of the mediator complex
-
Conaway RC, Conaway JW (2011) Function and regulation of the mediator complex. Curr Opin Genet Dev 21:225-230
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 225-230
-
-
Conaway, R.C.1
Conaway, J.W.2
-
13
-
-
84863621527
-
Cancer epigenetics: From mechanism to therapy
-
Dawson MA, Kouzarides T (2012) Cancer epigenetics: from mechanism to therapy. Cell 150:1227
-
(2012)
Cell
, vol.150
, pp. 1227
-
-
Dawson, M.A.1
Kouzarides, T.2
-
14
-
-
0033578354
-
Anti-repression of polymerase II transcription by a designed ligand
-
Dickinson LA, Trauger JW, Baird EE et al (1999) Anti-repression of polymerase II transcription by a designed ligand. Biochemistry 38:10801-10807
-
(1999)
Biochemistry
, vol.38
, pp. 10801-10807
-
-
Dickinson, L.A.1
Trauger, J.W.2
Baird, E.E.3
-
15
-
-
0026598102
-
Nucleosome loss activates CUP1 and HIS3 promoters to fully induced levels in the yeast Saccharomyces cerevisiae
-
Durrin LK, Mann RK, Grunstein M (1992) Nucleosome loss activates CUP1 and HIS3 promoters to fully induced levels in the yeast Saccharomyces cerevisiae. Mol Cell Biol 12:1621-1629
-
(1992)
Mol Cell Biol
, vol.12
, pp. 1621-1629
-
-
Durrin, L.K.1
Mann, R.K.2
Grunstein, M.3
-
16
-
-
0020699979
-
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
-
Feinberg AP, Vogelstein B (1983) Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301:89-92
-
(1983)
Nature
, vol.301
, pp. 89-92
-
-
Feinberg, A.P.1
Vogelstein, B.2
-
18
-
-
84859610741
-
Mutations in the mediator subunit MED23 link intellectual disability to immediate early gene regulation
-
Goh YS, Grants JM (2012) Mutations in the mediator subunit MED23 link intellectual disability to immediate early gene regulation. Clin Genet 81:430-432
-
(2012)
Clin Genet
, vol.81
, pp. 430-432
-
-
Goh, Y.S.1
Grants, J.M.2
-
19
-
-
84860340270
-
A cardiac microRNA governs systemic energy homeostasis by regulation of MED13
-
Grueter CE, van Rooij E, Johnson BA et al (2012) A cardiac microRNA governs systemic energy homeostasis by regulation of MED13. Cell 149:671-683
-
(2012)
Cell
, vol.149
, pp. 671-683
-
-
Grueter, C.E.1
Van Rooij, E.2
Johnson, B.A.3
-
20
-
-
79959739474
-
The impact of epigenomics on future drug design and new therapies
-
Hamm CA, Costa FF (2011) The impact of epigenomics on future drug design and new therapies. Drug Discov Today 16:626-635
-
(2011)
Drug Discov Today
, vol.16
, pp. 626-635
-
-
Hamm, C.A.1
Costa, F.F.2
-
21
-
-
84888235608
-
A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell
-
Han L, Pandian GN, Junetha S et al (2013) A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell. Angew Chem Int Ed. doi: 10.1002/anie.201306766
-
(2013)
Angew Chem Int Ed
-
-
Han, L.1
Pandian, G.N.2
Junetha, S.3
-
22
-
-
79955027617
-
Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart
-
He A, Kong SW, Ma Q et al (2011) Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart. Proc Natl Acad Sci USA 108:5632-5637
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 5632-5637
-
-
He, A.1
Kong, S.W.2
Ma, Q.3
-
23
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer D, Wang H, Kiani S et al (2011) Genetic engineering of human pluripotent cells using TALE nucleases. Nat Biotechnol 29:731-734
-
(2011)
Nat Biotechnol
, vol.29
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.2
Kiani, S.3
-
24
-
-
25444475263
-
Li-Fraumeni syndrome: A p53 family affair
-
Iwakuma T, Lozano G, Flores ER (2005) Li-Fraumeni syndrome: a p53 family affair. Cell Cycle 4:865-867
-
(2005)
Cell Cycle
, vol.4
, pp. 865-867
-
-
Iwakuma, T.1
Lozano, G.2
Flores, E.R.3
-
25
-
-
54249116230
-
Genetic regulatory mechanisms in the synthesis of proteins
-
Jacob F, Monod J (1961) Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol 3:318-356
-
(1961)
J Mol Biol
, vol.3
, pp. 318-356
-
-
Jacob, F.1
Monod, J.2
-
27
-
-
84871519181
-
TALENs: A widely applicable technology for targeted genome editing
-
Joung JK, Sander JD (2013) TALENs: a widely applicable technology for targeted genome editing. Nat Rev Mol Cell Biol 14:49-55
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 49-55
-
-
Joung, J.K.1
Sander, J.D.2
-
28
-
-
67649975232
-
Creating zinc monkey wrenches in the treatment of epigenetic disorders
-
Kalin JH, Butler KV, Kozikowski AP (2009) Creating zinc monkey wrenches in the treatment of epigenetic disorders. Curr Opin Chem Biol 13:263-271
-
(2009)
Curr Opin Chem Biol
, vol.13
, pp. 263-271
-
-
Kalin, J.H.1
Butler, K.V.2
Kozikowski, A.P.3
-
29
-
-
84858037284
-
Synthesis and biological properties of highly sequence specific-alkylating N-methylpyrrole-N-methylimidazole polyamide conjugates
-
Kashiwazaki G, Bando T, Yoshidome T et al (2012) Synthesis and biological properties of highly sequence specific-alkylating N-methylpyrrole-N-methylimidazole polyamide conjugates. J Med Chem 55:2057-2066
-
(2012)
J Med Chem
, vol.55
, pp. 2057-2066
-
-
Kashiwazaki, G.1
Bando, T.2
Yoshidome, T.3
-
30
-
-
0032059111
-
Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast
-
Keaveney M, Struhl K (1998) Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast. Mol Cell 1:917-924
-
(1998)
Mol Cell
, vol.1
, pp. 917-924
-
-
Keaveney, M.1
Struhl, K.2
-
31
-
-
0035807360
-
A forkhead-domain gene is mutated in a severe speech and language disorder
-
Lai CSL, Fisher SE, Hurst JA et al (2001) A forkhead-domain gene is mutated in a severe speech and language disorder. Nature 413:519-523
-
(2001)
Nature
, vol.413
, pp. 519-523
-
-
Lai, C.1
Fisher, S.E.2
Hurst, J.A.3
-
32
-
-
0442267478
-
-
MIT Press, Cambridge, MA
-
Lamb MJ, Jablonka E (2005) Evolution in four dimensions: genetic, epigenetic, behavioral, and symbolic variation in the history of life. MIT Press, Cambridge, MA, pp 5-34
-
(2005)
Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life
, pp. 5-34
-
-
Lamb, M.J.1
Jablonka, E.2
-
33
-
-
77951233113
-
Transcriptional switches: Chemical approaches to gene regulation
-
Lee LW, Mapp AK (2010) Transcriptional switches: chemical approaches to gene regulation. J Biol Chem 285:11033-11038
-
(2010)
J Biol Chem
, vol.285
, pp. 11033-11038
-
-
Lee, L.W.1
Mapp, A.K.2
-
34
-
-
84875198920
-
Transcriptional regulation and its misregulation in disease
-
Lee TI, Young RA (2013) Transcriptional regulation and its misregulation in disease. Cell 152:1237-1251
-
(2013)
Cell
, vol.152
, pp. 1237-1251
-
-
Lee, T.I.1
Young, R.A.2
-
35
-
-
79952352904
-
Neurotensin receptor 1 gene (NTSR1) polymorphism is associated with working memory
-
Li J, Chen C, Chen C et al (2011) Neurotensin receptor 1 gene (NTSR1) polymorphism is associated with working memory. PLoS ONE 6(3):e17365
-
(2011)
Plos ONE
, vol.6
, Issue.3
-
-
Li, J.1
Chen, C.2
Chen, C.3
-
36
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-Myc
-
Lin CY, Loven J, Rahl PB et al (2012) Transcriptional amplification in tumor cells with elevated c-Myc. Cell 151:56-67
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
Loven, J.2
Rahl, P.B.3
-
37
-
-
79955857476
-
Involvement of a novel GATA4 mutation in atrial septal defects
-
Liu XY, Wang J, Zheng JH et al (2011) Involvement of a novel GATA4 mutation in atrial septal defects. Int J Mol Med 28:17-23
-
(2011)
Int J Mol Med
, vol.28
, pp. 17-23
-
-
Liu, X.Y.1
Wang, J.2
Zheng, J.H.3
-
38
-
-
84864020768
-
The super elongation complex family of RNA polymerase II elongation factors: Gene target specificity and transcriptional output
-
Luo Z, Lin C, Guest E et al (2012) The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output. Mol Cell Biol 32:2608-2617
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2608-2617
-
-
Luo, Z.1
Lin, C.2
Guest, E.3
-
39
-
-
38449088965
-
Distinct roles of HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth
-
Maestro MA, Cardalda C, Boj SF et al (2007) Distinct roles of HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth. Endocr Dev 12:33-45
-
(2007)
Endocr Dev
, vol.12
, pp. 33-45
-
-
Maestro, M.A.1
Cardalda, C.2
Boj, S.F.3
-
40
-
-
15744394650
-
Functional specificity of artificial transcriptional activators
-
Majmudar CY, Lum JK, Prasov L et al (2005) Functional specificity of artificial transcriptional activators. Chem Biol 12:313-321
-
(2005)
Chem Biol
, vol.12
, pp. 313-321
-
-
Majmudar, C.Y.1
Lum, J.K.2
Prasov, L.3
-
41
-
-
84857029597
-
The crystal structure of TAL effector PthXo1 bound to its DNA target
-
Mak AN, Bradley P, Cernadas RA et al (2012) The crystal structure of TAL effector PthXo1 bound to its DNA target. Science 335:716-719
-
(2012)
Science
, vol.335
, pp. 716-719
-
-
Mak, A.N.1
Bradley, P.2
Cernadas, R.A.3
-
42
-
-
80053581321
-
The dark side of cohesin: The carcinogenic point of view
-
Mannini L, Musio A (2011) The dark side of cohesin: the carcinogenic point of view. Mutat Res 728:81-87
-
(2011)
Mutat Res
, vol.728
, pp. 81-87
-
-
Mannini, L.1
Musio, A.2
-
43
-
-
0034635990
-
Activation of gene expression by small molecule transcription factors
-
Mapp AK, Ansari AZ, Ptashne M et al (2000) Activation of gene expression by small molecule transcription factors. Proc Natl Acad Sci USA 97:3930-3935
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3930-3935
-
-
Mapp, A.K.1
Ansari, A.Z.2
Ptashne, M.3
-
44
-
-
84885342039
-
Chemically induced pluripotent stem cells (CiPSCs): A transgene-free approach
-
Masuda S, Wu J, Hishida T et al (2013) Chemically induced pluripotent stem cells (CiPSCs): a transgene-free approach. J Mol Cell Biol 5:354-355
-
(2013)
J Mol Cell Biol
, vol.5
, pp. 354-355
-
-
Masuda, S.1
Wu, J.2
Hishida, T.3
-
45
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory DNA
-
Maurano MT, Humbert R, Rynes E et al (2012) Systematic localization of common disease-associated variation in regulatory DNA. Science 337:1190-1195
-
(2012)
Science
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
Humbert, R.2
Rynes, E.3
-
46
-
-
84858770543
-
Transcription factor pathways and congenital heart disease
-
McCulley DJ, Black BL (2012) Transcription factor pathways and congenital heart disease. Curr Top Dev Biol 100:253-277
-
(2012)
Curr Top Dev Biol
, vol.100
, pp. 253-277
-
-
Mc Culley, D.J.1
Black, B.L.2
-
47
-
-
84858378568
-
Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns
-
Meier JL, Montgomery DC, Dervan PB (2012) Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns. Nucleic Acids Res 40:2345-2356
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 2345-2356
-
-
Meier, J.L.1
Montgomery, D.C.2
Dervan, P.B.3
-
48
-
-
84870579235
-
Chimeric TALE recombinases with programmable DNA sequence specificity
-
Mercer AC, Gaj T, Fuller RP (2012) Chimeric TALE recombinases with programmable DNA sequence specificity. Nucleic Acids Res 40:11163-11172
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 11163-11172
-
-
Mercer, A.C.1
Gaj, T.2
Fuller, R.P.3
-
49
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller JC, Tan S, Qiao G et al (2011) A TALE nuclease architecture for efficient genome editing. Nat Biotechnol 29:143-148
-
(2011)
Nat Biotechnol
, vol.29
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.2
Qiao, G.3
-
50
-
-
0015503810
-
Nucleotide sequence of the gene coding for the bacteriophage MS2 coat protein
-
Min JW, Haegeman G, Ysebaert M et al (1972) Nucleotide sequence of the gene coding for the bacteriophage MS2 coat protein. Nature 237:82-88
-
(1972)
Nature
, vol.237
, pp. 82-88
-
-
Min, J.W.1
Haegeman, G.2
Ysebaert, M.3
-
51
-
-
70450196195
-
TrkB signalling pathways in LTP and learning
-
Minichiello L (2009) TrkB signalling pathways in LTP and learning. Nat Rev Neurosci 10:850-860
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 850-860
-
-
Minichiello, L.1
-
52
-
-
80053039555
-
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
-
Mussolino C, Morbitzer R, Liitge F et al (2011) A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. Nucleic Acids Res 39:9283-9293
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 9283-9293
-
-
Mussolino, C.1
Morbitzer, R.2
Liitge, F.3
-
53
-
-
10744227070
-
Control of pancreas and liver gene expression by HNF transcription factors
-
Odom DT, Zizlsperger N, Gordon DB et al (2004) Control of pancreas and liver gene expression by HNF transcription factors. Science 303:1378-1381
-
(2004)
Science
, vol.303
, pp. 1378-1381
-
-
Odom, D.T.1
Zizlsperger, N.2
Gordon, D.B.3
-
54
-
-
70449095972
-
Synthesis and properties of PI polyamide-SAHA conjugate
-
Ohtsuki A, Kimura MT, Minoshima M et al (2009) Synthesis and properties of PI polyamide-SAHA conjugate. Tetrahedron Lett 50:7288-7292
-
(2009)
Tetrahedron Lett
, vol.50
, pp. 7288-7292
-
-
Ohtsuki, A.1
Kimura, M.T.2
Minoshima, M.3
-
55
-
-
33749361499
-
Gene regulatory networks in the evolution and development of the heart
-
Olson EN (2006) Gene regulatory networks in the evolution and development of the heart. Science 313:1922-1927
-
(2006)
Science
, vol.313
, pp. 1922-1927
-
-
Olson, E.N.1
-
56
-
-
78650511336
-
A de novo mutation in NKX2.5 associated with atrial septal defects, ventricular noncompaction, syncope and sudden death
-
Ouyang P, Saarel E, Bai Y et al (2011) A de novo mutation in NKX2.5 associated with atrial septal defects, ventricular noncompaction, syncope and sudden death. Clin Chim Acta 412:170-175
-
(2011)
Clin Chim Acta
, vol.412
, pp. 170-175
-
-
Ouyang, P.1
Saarel, E.2
Bai, Y.3
-
57
-
-
84861789192
-
Programmable genetic switches to control transcriptional machinery of pluripotency
-
Pandian GN, Sugiyama H (2012) Programmable genetic switches to control transcriptional machinery of pluripotency. Biotechnol J 7:798-809
-
(2012)
Biotechnol J
, vol.7
, pp. 798-809
-
-
Pandian, G.N.1
Sugiyama, H.2
-
58
-
-
84872154399
-
Strategies to modulate heritable epigenetic defects in cellular machinery: Lessons from nature
-
Pandian GN, Sugiyama H (2013) Strategies to modulate heritable epigenetic defects in cellular machinery: lessons from nature. Pharmaceuticals 6:1-24
-
(2013)
Pharmaceuticals
, vol.6
, pp. 1-24
-
-
Pandian, G.N.1
Sugiyama, H.2
-
59
-
-
83355175582
-
Synthetic small molecules for epigenetic activation of pluripotency genes in mouse embryonic fibroblasts
-
Pandian GN, Shinohara K, Ohtsuki A et al (2011) Synthetic small molecules for epigenetic activation of pluripotency genes in mouse embryonic fibroblasts. ChemBioChem 12:2822-2828
-
(2011)
Chembiochem
, vol.12
, pp. 2822-2828
-
-
Pandian, G.N.1
Shinohara, K.2
Ohtsuki, A.3
-
60
-
-
84859436791
-
Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes
-
Pandian GN, Ohtsuki A, Bando T et al (2012a) Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes. Bioorg Med Chem 20(8):2656-2660
-
(2012)
Bioorg Med Chem
, vol.20
, Issue.8
, pp. 2656-2660
-
-
Pandian, G.N.1
Ohtsuki, A.2
Bando, T.3
-
61
-
-
84864850639
-
A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblast
-
Pandian GN, Nakano Y, Sato S et al (2012b) A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblast. Sci Rep 2:e544
-
(2012)
Sci Rep
, vol.2
-
-
Pandian, G.N.1
Nakano, Y.2
Sato, S.3
-
62
-
-
84893124716
-
Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts
-
Pandian GN, Taniguchi J, Junetha S et al (2014) Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts. Sci Rep 4:e3843
-
(2014)
Sci Rep
, vol.4
-
-
Pandian, G.N.1
Taniguchi, J.2
Junetha, S.3
-
63
-
-
46949095221
-
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
-
Perez EE, Wang J, Miller JC et al (2008) Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat Biotechnol 26:808-816
-
(2008)
Nat Biotechnol
, vol.26
, pp. 808-816
-
-
Perez, E.E.1
Wang, J.2
Miller, J.C.3
-
65
-
-
0004211673
-
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
Ptashne M, Gann A (2002) Genes and signals. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
(2002)
Genes and Signals
-
-
Ptashne, M.1
Gann, A.2
-
66
-
-
84860371870
-
Combinatorial complexity in chromatin structure and function: Revisiting the histone code
-
Rando OJ (2012) Combinatorial complexity in chromatin structure and function: revisiting the histone code. Curr Opin Genet Dev 22:148-155
-
(2012)
Curr Opin Genet Dev
, vol.22
, pp. 148-155
-
-
Rando, O.J.1
-
67
-
-
84860747716
-
FLASH assembly of TALENs for high-throughput genome editing
-
Reyon D, Tsai SQ, Khayter C et al (2012) FLASH assembly of TALENs for high-throughput genome editing. Nat Biotechnol 30:460-465
-
(2012)
Nat Biotechnol
, vol.30
, pp. 460-465
-
-
Reyon, D.1
Tsai, S.Q.2
Khayter, C.3
-
68
-
-
0032547382
-
The use of chromatin templates to recreate transcriptional regulatory phenomena in vitro
-
Robinson KM, Kadonaga JT (1998) The use of chromatin templates to recreate transcriptional regulatory phenomena in vitro. Biochim Biophys Acta 1378:1-6
-
(1998)
Biochim Biophys Acta
, vol.1378
, pp. 1-6
-
-
Robinson, K.M.1
Kadonaga, J.T.2
-
69
-
-
78650922822
-
A novel mutation in MED12 causes FG syndrome (OpitzKaveggia syndrome)
-
Rump P, Niessen RC, Verbruggen KT et al (2011) A novel mutation in MED12 causes FG syndrome (OpitzKaveggia syndrome). Clin Genet 79:183-188
-
(2011)
Clin Genet
, vol.79
, pp. 183-188
-
-
Rump, P.1
Niessen, R.C.2
Verbruggen, K.T.3
-
70
-
-
84863657985
-
Temporal profiling of gene networks associated with the late phase of long-term potentiation in vivo
-
Ryan MM, Ryan B, Smith MK et al (2012) Temporal profiling of gene networks associated with the late phase of long-term potentiation in vivo. PLoS ONE 7:e40538
-
(2012)
Plos ONE
, vol.7
-
-
Ryan, M.M.1
Ryan, B.2
Smith, M.K.3
-
71
-
-
84879027684
-
Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity
-
Saha A, Pandian GN, Sato S et al (2013) Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity. Bioorg Med Chem 21:4201-4209
-
(2013)
Bioorg Med Chem
, vol.21
, pp. 4201-4209
-
-
Saha, A.1
Pandian, G.N.2
Sato, S.3
-
72
-
-
84865109759
-
Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia
-
Sanda T, Lawton LN, Barrasa MI et al (2012) Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia. Cancer Cell 22:209-221
-
(2012)
Cancer Cell
, vol.22
, pp. 209-221
-
-
Sanda, T.1
Lawton, L.N.2
Barrasa, M.I.3
-
73
-
-
84868344895
-
SWI/SNF complex in disorder: Switching from malignancies to intellectual disability
-
Santen GW, Kriek M, van Attikum H (2012) SWI/SNF complex in disorder: Switching from malignancies to intellectual disability. Epigenetics 7:1219-1224
-
(2012)
Epigenetics
, vol.7
, pp. 1219-1224
-
-
Santen, G.W.1
Kriek, M.2
Van Attikum, H.3
-
75
-
-
80054918967
-
In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases
-
Sebastiano V, Maeder ML, Angstman JF et al (2011) In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells 29:1717-1726
-
(2011)
Stem Cells
, vol.29
, pp. 1717-1726
-
-
Sebastiano, V.1
Maeder, M.L.2
Angstman, J.F.3
-
77
-
-
1642291800
-
A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction
-
Shimogawa H, Kwon Y, Mao Q et al (2004) A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction. J Am Chem Soc 126:3461-3471
-
(2004)
J am Chem Soc
, vol.126
, pp. 3461-3471
-
-
Shimogawa, H.1
Kwon, Y.2
Mao, Q.3
-
78
-
-
79960833952
-
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
-
Soldner F, Laganiere J, Cheng AW et al (2011) Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell 146:318-331
-
(2011)
Cell
, vol.146
, pp. 318-331
-
-
Soldner, F.1
Laganiere, J.2
Cheng, A.W.3
-
79
-
-
84891385829
-
Transcription activator-like effector nucleases (TALENs): A highly efficient and versatile tool for genome editing
-
Sun N, Zhao H (2013) Transcription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing. Biotechnol Bioeng 110:1811-1821
-
(2013)
Biotechnol Bioeng
, vol.110
, pp. 1811-1821
-
-
Sun, N.1
Zhao, H.2
-
80
-
-
78951482163
-
Complex congenital heart disease in unaffected relatives of adults with 22q11.2 deletion syndrome
-
Swaby JA, Silversides CK, Bekeschus SC et al (2011) Complex congenital heart disease in unaffected relatives of adults with 22q11.2 deletion syndrome. Am J Cardiol 107:466-471
-
(2011)
Am J Cardiol
, vol.107
, pp. 466-471
-
-
Swaby, J.A.1
Silversides, C.K.2
Bekeschus, S.C.3
-
81
-
-
84867582231
-
Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazolepolyamides in mice
-
Synold TW, Xi B, Wu J et al (2012) Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazolepolyamides in mice. Cancer Chemother Pharmacol 70:617-625
-
(2012)
Cancer Chemother Pharmacol
, vol.70
, pp. 617-625
-
-
Synold, T.W.1
Xi, B.2
Wu, J.3
-
82
-
-
83755186736
-
Depletion of 14-3-3 protein exacerbates cardiac oxidative stress, inflammation and remodeling process via modulation of MAPK/NF-kB signaling pathways after streptozotocin-induced diabetes mellitus
-
Thandavarayan RA, Giridharan VV, Sari FR et al (2011) Depletion of 14-3-3 protein exacerbates cardiac oxidative stress, inflammation and remodeling process via modulation of MAPK/NF-kB signaling pathways after streptozotocin-induced diabetes mellitus. Cell Physiol Biochem 28:911-922
-
(2011)
Cell Physiol Biochem
, vol.28
, pp. 911-922
-
-
Thandavarayan, R.A.1
Giridharan, V.V.2
Sari, F.R.3
-
83
-
-
0000739713
-
Recognition of 16 base Pairs in the minor groove of DNA by a pyrrole-imidazole polyamide dimer
-
Trauger JW, Baird EE, Dervan PB (1998) Recognition of 16 base Pairs in the minor groove of DNA by a pyrrole-imidazole polyamide dimer. J Am Chem Soc 120:3534-3535
-
(1998)
J am Chem Soc
, vol.120
, pp. 3534-3535
-
-
Trauger, J.W.1
Baird, E.E.2
Dervan, P.B.3
-
84
-
-
84867196824
-
Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugates as sequence-selective DNA probes
-
Vaijayanthi T, Bando T, Pandian GN et al (2012) Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugates as sequence-selective DNA probes. ChemBioChem 13:2170-2185
-
(2012)
Chembiochem
, vol.13
, pp. 2170-2185
-
-
Vaijayanthi, T.1
Bando, T.2
Pandian, G.N.3
-
85
-
-
84873306466
-
Design of a new fluorescent probe: Pyrrole/imidazole hairpin polyamides with pyrene conjugation at their y-turn
-
Vaijayanthi T, Bando T, Hashiya K et al (2013) Design of a new fluorescent probe: pyrrole/imidazole hairpin polyamides with pyrene conjugation at their y-turn. Bioorg Med Chem 21:852-855
-
(2013)
Bioorg Med Chem
, vol.21
, pp. 852-855
-
-
Vaijayanthi, T.1
Bando, T.2
Hashiya, K.3
-
86
-
-
0141988965
-
Targeting the transcriptional machinery with unique artificial transcriptional activators
-
Wu ZQ, Belanger G, Brennan BB et al (2003) Targeting the transcriptional machinery with unique artificial transcriptional activators. J Am Chem Soc 125:12390-12391
-
(2003)
J am Chem Soc
, vol.125
, pp. 12390-12391
-
-
Wu, Z.Q.1
Belanger, G.2
Brennan, B.B.3
-
87
-
-
84888263841
-
Clinical grade iPS cells: Need for versatile small molecules and optimal cell sources
-
Wu YL, Pandian GN, Ding YP et al (2013) Clinical grade iPS cells: need for versatile small molecules and optimal cell sources. Chem Biol 20:1311-1322
-
(2013)
Chem Biol
, vol.20
, pp. 1311-1322
-
-
Wu, Y.L.1
Pandian, G.N.2
Ding, Y.P.3
-
88
-
-
80054987997
-
Targeted gene correction of a1-antitrypsin deficiency in induced pluripotent stem cells
-
Yusa K, Rashid ST, Marchand HS et al (2011) Targeted gene correction of a1-antitrypsin deficiency in induced pluripotent stem cells. Nature 478:391-394
-
(2011)
Nature
, vol.478
, pp. 391-394
-
-
Yusa, K.1
Rashid, S.T.2
Marchand, H.S.3
-
89
-
-
84861857476
-
RNA polymerase II elongation control
-
Zhou Q, Li T, Price DH (2012) RNA polymerase II elongation control. Annu Rev Biochem 81:119-143
-
(2012)
Annu Rev Biochem
, vol.81
, pp. 119-143
-
-
Zhou, Q.1
Li, T.2
Price, D.H.3
|