A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell

Angewandte Chemie - International Edition

Volumn 52, Issue 50, 2013, Pages 13410-13413

  Han, Le ^a   Pandian, Ganesh N ^c   Junetha, Syed ^a   Sato, Shinsuke ^c   Anandhakumar, Chandran ^a   Taniguchi, Junichi ^a   Saha, Abhijit ^a   Bando, Toshikazu ^a   Nagase, Hiroki ^d   Sugiyama, Hiroshi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c KYOTO UNIVERSITY   (Japan)

^d NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

DNA recognition; genetic switches; polymerase chain reaction; proteins; synthetic biology

Indexed keywords

DNA RECOGNITION; EPIGENOMES; GENE SWITCH; GENETIC SWITCHES; SMALL MOLECULES; SOMATIC CELLS; SYNTHETIC BIOLOGY; TRANSCRIPTIONAL ACTIVATIONS;

GENES; MOLECULES; POLYMERASE CHAIN REACTION; PROTEINS;

CELLS;

HYDROXAMIC ACID; IMIDAZOLE; IMIDAZOLE DERIVATIVE; NYLON; PROTEIN; PYRROLE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DNA RECOGNITION; DRUG EFFECT; GENETIC SWITCHES; GENETICS; GERM CELL; HUMAN; METABOLISM; PATHOLOGY; PLURIPOTENT STEM CELL; POLYMERASE CHAIN REACTION; SYNTHESIS; SYNTHETIC BIOLOGY; TRANSCRIPTION INITIATION;

DNA RECOGNITION; GENETIC SWITCHES; POLYMERASE CHAIN REACTION; PROTEINS; SYNTHETIC BIOLOGY;

GERM CELLS; HUMANS; HYDROXAMIC ACIDS; IMIDAZOLES; MOLECULAR STRUCTURE; NYLONS; PLURIPOTENT STEM CELLS; PYRROLES; TRANSCRIPTIONAL ACTIVATION;

EID: 84888235608     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201306766     Document Type: Article

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