Strategies to modulate heritable epigenetic defects in cellular machinery: Lessons from nature

Pharmaceuticals

Volumn 6, Issue 1, 2012, Pages

  Pandian, Ganesh N ^a   Sugiyama, Hiroshi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Cancer treatment; Chemical mimics; Epigenetic inheritance; Epigenetic switch based therapy; Future medicine; HDAC inhibitors; Histone code; Programmable genetic switches; Regenerative medicine

Indexed keywords

4 PHENYLBUTYRIC ACID; 6 (1,3 DIOXO 1H,3H BENZO[DE]ISOQUINOLIN 2 YL) N HYDROXYHEXANAMIDE; APICIDIN; BELINOSTAT; BENZAMIDE DERIVATIVE; BUTYRIC ACID; CHLAMYDOCIN; CYTARABINE; DACINOSTAT; ENTINOSTAT; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE INHIBITOR; IDARUBICIN; KETONE DERIVATIVE; M 344; M CARCOXYCINNAMIC ACID BISHYDROXAMIDE; OCTAMER TRANSCRIPTION FACTOR 4; OXAMFLATIN; SIRTUIN; TETRAPEPTIDE; TRANSCRIPTION FACTOR NANOG; TRICHOSTATIN A; UNCLASSIFIED DRUG; VALPROIC ACID; VORINOSTAT;

ACUTE GRANULOCYTIC LEUKEMIA; AGING; ANOREXIA; BASE PAIRING; BONE MARROW TOXICITY; BREAST CANCER; BREAST CARCINOMA; CANCER CHEMOTHERAPY; CARDIOTOXICITY; CELL DIFFERENTIATION; CELL REGENERATION; CELL RENEWAL; CUTANEOUS T CELL LYMPHOMA; DEHYDRATION; DIARRHEA; DNA METHYLATION; DNA REPAIR; DRUG FEVER; DRUG MECHANISM; DRUG SELECTIVITY; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; EPIGENETICS; FATIGUE; GENE EXPRESSION; GENE MUTATION; GENE REGULATORY NETWORK; GENE REPRESSION; GENE SWITCHING; GLIOBLASTOMA; HEAD AND NECK CANCER; HERITABILITY; HISTONE MODIFICATION; HOMEOSTASIS; HUMAN; INHERITANCE; LEUKEMIA; LYMPHOMA; MALIGNANT NEOPLASTIC DISEASE; MATERNAL CARE; MYELODYSPLASTIC SYNDROME; MYELOMA; NAUSEA; NAUSEA AND VOMITING; NEOPLASM; NEUROTOXICITY; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; REVIEW; SOLID TUMOR;

EID: 84872154399     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph6010001     Document Type: Review

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