메뉴 건너뛰기




Volumn 125, Issue 41, 2003, Pages 12390-12391

Targeting the transcriptional machinery with unique artificial transcriptional activators

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; DNA; HYBRID PROTEIN; LIGAND; NUCLEIC ACID; OLIGONUCLEOTIDE; PEPTIDE; PEPTIDE LIBRARY; POLYAMIDE; REGULATOR PROTEIN; RNA POLYMERASE II; TRANSCRIPTIONAL ACTIVATOR; UNCLASSIFIED DRUG;

EID: 0141988965     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja036685v     Document Type: Article
Times cited : (29)

References (28)
  • 1
    • 0345849436 scopus 로고    scopus 로고
    • Cold Spring Harbor Laboratory: New York
    • Ptashne, M.; Gann, A. Genes & Signals; Cold Spring Harbor Laboratory: New York, 2001.
    • (2001) Genes & Signals
    • Ptashne, M.1    Gann, A.2
  • 2
    • 0035962636 scopus 로고    scopus 로고
    • (a) Pandolfi, P. P. Oncogene 2001, 20, 3116-3127.
    • (2001) Oncogene , vol.20 , pp. 3116-3127
    • Pandolfi, P.P.1
  • 9
    • 0023649184 scopus 로고
    • (b) Ma, J.; Ptashne, M. Cell 1987, 51, 113-119.
    • (1987) Cell , vol.51 , pp. 113-119
    • Ma, J.1    Ptashne, M.2
  • 25
    • 0034283159 scopus 로고    scopus 로고
    • and references therein
    • (b) Melcher, K. J. Mol. Biol. 2000, 301, 1097-1112 and references therein.
    • (2000) J. Mol. Biol. , vol.301 , pp. 1097-1112
    • Melcher, K.1
  • 27
    • 0141928489 scopus 로고    scopus 로고
    • note
    • In the case of two ADs that target the same binding site, the affinity of each AD for that site would presumably strongly affect functional potency.
  • 28
    • 0037473529 scopus 로고    scopus 로고
    • An alternate approach for developing nonbiopolymer-based ADs is to identify molecules that inhibit activator-target protein interactions. One such inhibitor was recently reported, although its function as an AD has not yet been described: Asada, S.; Choi, Y.; Uesugi, M. J. Am. Chem. Soc. 2003, 125, 4992-4993.
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 4992-4993
    • Asada, S.1    Choi, Y.2    Uesugi, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.