Andrographolide protects liver cells from H2O2 induced cell death by upregulation of Nrf-2/HO-1 mediated via adenosine A2a receptor signalling

Biochimica et Biophysica Acta - General Subjects

Volumn 1860, Issue 11, 2016, Pages 2377-2390

  Mittal, Smriti P K ^a   Khole, Swati ^a   Jagadish, Nidhi ^b   Ghosh, Debjani ^b   Gadgil, Vijay ^b   Sinkar, Vilas ^b   Ghaskadbi, Saroj S ^a  

^a UNIVERSITY OF PUNE   (India)

^b Hindustan Lever Limited   (India)

Author keywords

GSK 3 ; HepG2 cells; MAP kinase; Nrf 2; Oxidative stress; Protein kinase A

Indexed keywords

ADENOSINE A2A RECEPTOR; ADENYLATE CYCLASE; ANDROGRAPHIS PANICULATA EXTRACT; ANDROGRAPHOLIDE; ANTIOXIDANT; CAFFEINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; HEME OXYGENASE 1; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; DITERPENE; NFE2L2 PROTEIN, HUMAN;

ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GENE EXPRESSION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER PROTECTION; MOLECULAR DOCKING; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UPREGULATION; CELL DEATH; DRUG EFFECTS; GENETICS; HEP-G2 CELL LINE; METABOLISM;

ANTIOXIDANTS; CELL DEATH; DITERPENES; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; HYDROGEN PEROXIDE; NF-E2-RELATED FACTOR 2; RECEPTOR, ADENOSINE A2A; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84984652750     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2016.07.005     Document Type: Article

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