Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity

British Journal of Pharmacology

Volumn 168, Issue 7, 2013, Pages 1707-1718

  Guan, S P ^a   Tee, W ^a   Ng, D S W ^a   Chan, T K ^a   Peh, H Y ^a   Ho, W E ^b   Cheng, C ^a   Mak, J C ^c   Wong, W S F ^a,d  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

antioxidant; chronic obstructive pulmonary disease; glutathione; glutathione peroxidase; glutathione reductase; heme oxygenase 1

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 ISOPROSTANE; ANDROGRAPHOLIDE; CIGARETTE SMOKE; COMPLEMENTARY DNA; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEME OXYGENASE 1; INTERLEUKIN 1BETA; KERATINOCYTE DERIVED CHEMOKINE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BIOACCUMULATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; GENE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE TARGETING; GPX GENE; HO 1 GENE; HUMAN; HUMAN CELL; LUNG INJURY; LUNG LAVAGE; MOUSE; NONHUMAN; NRF2 GENE; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CYTOKINES; DITERPENES; FEMALE; GLUTATHIONE; HEME OXYGENASE-1; INFLAMMATION; LUNG; LUNG INJURY; MICE; MICE, INBRED BALB C; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; SMOKING; UP-REGULATION;

EID: 84875139247     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12054     Document Type: Article

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