Heme oxygenase-1-mediated reactive oxygen species reduction is involved in the inhibitory effect of curcumin on lipopolysaccharide-induced monocyte chemoattractant protein-1 production in RAW264.7 macrophages

Molecular Medicine Reports

Volumn 7, Issue 1, 2013, Pages 242-246

  Zhong, Yi ^a,b   Liu, Tingrong ^b   Lai, Wenyan ^b   Tan, Ying ^b   Tian, Di ^b   Guo, Zhigang ^b  

^a THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Curcumin; Heme oxygenase 1; Monocyte chemoattractant protein 1; Reactive oxygen species

Indexed keywords

APOCYNIN; CURCUMIN; HEME OXYGENASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTOPORPHYRIN ZINC; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; MACROPHAGE; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ANTIOXIDANTS; CELL LINE; CHEMOKINE CCL2; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PROTOPORPHYRINS; REACTIVE OXYGEN SPECIES;

EID: 84873825700     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.1138     Document Type: Article

References (32)

1. Libby P: Inflammation in atherosclerosis. Nature 420: 868-874, 2002.
2. Boring L, Gosling J, Cleary M and Charo IF: Decreased lesion formation in CCR2-/-mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 394: 894-897, 1998.
3. Surh YJ: Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review. Food Chem Toxicol 40: 1091-1097, 2002.
4. Goel A, Kunnumakkara AB and Aggarwal BB: Curcumin as 'Curecumin': from kitchen to clinic. Biochem Pharmacol75: 787-809, 2008.
5. Sumanont Y, Murakami Y, Tohda M, Vajragupta O, Matsumoto K and Watanabe H: Evaluation of the nitric oxide radical scavenging activity of manganese complexes of curcumin and its derivative. Biol Pharm Bull 27: 170-173, 2004.
6. Mahakunakorn P, Tohda M, Murakami Y, Matsumoto K, Watanabe H and Vajaragupta O: Cytoprotective and cytotoxic effects of curcumin: dual action on H2O2-induced oxidative cell damage in NG108-15 cells. Biol Pharm Bull 26: 725-728, 2003.
7. Montellano PR: The mechanism of heme oxygenase. Curr Opin Chem Biol 4: 221-227, 2000.
8. Durante W: Heme oxygenase-1 in growth control and its clinical application to vascular disease. J Cell Physiol 195: 373-382, 2003.
9. Yu JH, Kim KH, Kim DG and Kim H: Diphenyleneiodonium suppresses apoptosis in cerulein-stimulated pancreatic acinar cells. Int J Biochem Cell Biol 39: 2063-2075, 2007.
10. Laskin DL and Pendino KJ: Macrophages and inflammatory mediators in tissue injury. Annu Rev Pharmacol Toxicol35: 655-677, 1995.
11. Baggiolini M, Dewald B and Moser B: Human chemokines: an update. Annu Rev Immunol 15: 675-705, 1997.
12. Ryter SW, Alam J and Choi AM: Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev 86: 583-650, 2006.
13. Takahashi T, Morita K, Akagi R and Sassa S: Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries. Curr Med Chem 11: 1545-1561, 2004.
14. Kim AN, Jeon WK, Lee JJ and Kim BC: Up-regulation of heme oxygenase-1 expression through CaMKII-ERK1/2-Nrf2 signaling mediates the anti-inflammatory effect of bisdemethoxycurcumin in LPS-stimulated macrophages. Free Radic Biol Med 49: 323-331, 2010.
15. Jeong SO, Oh GS, Ha HY, etal: Dimethoxycurcumin, a synthetic curcumin analogue, induces heme oxygenase-1 expression through Nrf2 activation in RAW264.7 macrophages. J Clin Biochem Nutr 44: 79-84, 2009.
16. Kim KM, Pae HO, Zhung M, etal: Involvement of anti-inflammatory heme oxygenase-1 in the inhibitory effect of curcumin on the expression of pro-inflammatory inducible nitric oxide synthase in RAW264.7 macrophages. Biomed Pharmacother62: 630-636, 2008.
17. Seo WY, Ju SM, Song HY, etal: Celastrol suppresses IFN-gamma-induced ICAM-1 expression and subsequent monocyte adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells. Biochem Biophys Res Commun 398: 140-145, 2010.
18. Yu X, Tao W, Jiang F, Li C, Lin J and Liu C: Celastrol attenuates hypertension-induced inflammation and oxidative stress in vascular smooth muscle cells via induction of heme oxygenase-1. Am J Hypertens 23: 895-903, 2010.
19. Chen YC, Chen CH, Ko WS, Cheng CY, Sue YM and Chen TH: Dipyridamole inhibits lipopolysaccharide-induced cyclooxygenase-2 and monocyte chemoattractant protein-1 via heme oxygenase-1-mediated reactive oxygen species reduction in rat mesangial cells. Eur J Pharmacol 650: 445-450, 2011.
20. Panicker SR and Kartha CC: Curcumin attenuates glucose-induced monocyte chemoattractant protein-1 synthesis in aortic endothelial cells by modulating the nuclear factor-kappaB pathway. Pharmacology 85: 18-26, 2010.
21. Lim JH and Kwon TK: Curcumin inhibits phorbol myristate acetate (PMA)-induced MCP-1 expression by inhibiting ERK and NF-kappaB transcriptional activity. Food Chem Toxicol 48: 47-52, 2010.
22. Halliwell B: Mechanisms involved in the generation of free radicals. Pathol Biol (Paris) 44: 6-13, 1996.
23. Nakahira K, Haspel JA, Rathinam VA, etal: Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 12: 222-230, 2011.
24. Zhou R, Yazdi AS, Menu P and Tschopp J: A role for mitochondria in NLRP3 inflammasome activation. Nature 469: 221-225, 2011.
25. Blüthgen N and Legewie S: Systems analysis of MAPK signal transduction. Essays Biochem 45: 95-107, 2008.
26. Turjanski AG, Vaqué JP and Gutkind JS: MAP kinases and the control of nuclear events. Oncogene 26: 3240-3253, 2007.
27. Laderoute KR and Webster KA: Hypoxia/reoxygenation stimulates Jun kinase activity through redox signaling in cardiac myocytes. Circ Res 80: 336-344, 1997.
28. 2. Role in cell survival following oxidant injury. J Biol Chem 271: 4138-4142, 1996.
29. Ushio-Fukai M, Alexander RW, Akers M and Griendling KK: p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensinII. Role in vascular smooth muscle cell hypertrophy. J Biol Chem 273: 15022-15029, 1998.
30. Lander HM: An essential role for free radicals and derived species in signal transduction. FASEB J 11: 118-124, 1997.
31. Takaya K, Koya D, Isono M, etal: Involvement of ERK pathway in albumin-induced MCP-1 expression in mouse proximal tubular cells. Am J Physiol Renal Physiol 284: 1037-1045, 2003.
32. Hong MH, Kim MH, Chang HJ, etal: (-)-Epigallocatechin-3-gallate inhibits monocyte chemotactic protein-1 expression in endothelial cells via blocking NF-kappaB signaling. Life Sci 80: 1957-1965, 2007.