Liver-specific loss of perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 310, Issue 9, 2016, Pages G726-G738

  Najt, Charles P ^a   Senthivinayagam, Subramanian ^a   Aljazi, Mohammad B ^a   Fader, Kelly A ^a   Olenic, Sandra D ^a   Brock, Julienne R L ^a   Lydic, Todd A ^b   Jones, A Daniel ^a,b   Atshaves, Barbara P ^a  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Lipid droplets; Methioninecholine deficient diet; Nonalcoholic steatohepatitis; Perilipin 2

Indexed keywords

3 HYDROXYBUTYRIC ACID; CYCLOOXYGENASE 2; FAT DROPLET; HEAT SHOCK PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; PERILIPIN; PERILIPIN 2; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; ADIPOPHILIN; CCAAT ENHANCER BINDING PROTEIN; CYTOKINE; INTERLEUKIN 1BETA CONVERTING ENZYME; LOW DENSITY LIPOPROTEIN; METHIONINE; PEMT PROTEIN, MOUSE; PLIN2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET INDUCED HEPATIC FIBROSIS; DIET INDUCED HEPATIC INFLAMMATION; DIET INDUCED HEPATIC STEATOSIS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; EXPERIMENTAL FATTY LIVER; EXPERIMENTAL HEPATITIS; EXPERIMENTAL LIVER FIBROSIS; LIPID BLOOD LEVEL; LIPID METABOLISM; LIPID STORAGE; LIPOLYSIS; LIVER FUNCTION; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SECRETION; ANIMAL; C57BL MOUSE; COMPLICATION; DEFICIENCY; GENETICS; LIVER; LIVER CIRRHOSIS; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; VITAMIN DEFICIENCY;

ANIMALS; CASPASE 1; CCAAT-ENHANCER-BINDING PROTEINS; CHOLINE DEFICIENCY; CYTOKINES; LIPOPROTEINS, LDL; LIVER; LIVER CIRRHOSIS; METHIONINE; MICE; MICE, INBRED C57BL; NON-ALCOHOLIC FATTY LIVER DISEASE; PERILIPIN-2; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE; TRIGLYCERIDES;

EID: 84984604142     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00436.2015     Document Type: Article

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