메뉴 건너뛰기




Volumn 132, Issue 5, 2007, Pages 1947-1954

Reduction of Hepatosteatosis and Lipid Levels by an Adipose Differentiation-Related Protein Antisense Oligonucleotide

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOPHILIN; ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; TRIACYLGLYCEROL;

EID: 34247641706     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2007.02.046     Document Type: Article
Times cited : (137)

References (37)
  • 1
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 346 (2002) 1221-1231
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 2
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark J.M., Brancati F.L., and Diehl A.M. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 98 (2003) 960-967
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 5
    • 0026668669 scopus 로고
    • Isolation and characterization of a full-length cDNA coding for an adipose differentiation-related protein
    • Jiang H.P., and Serrero G. Isolation and characterization of a full-length cDNA coding for an adipose differentiation-related protein. Proc Natl Acad Sci U S A 89 (1992) 7856-7860
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 7856-7860
    • Jiang, H.P.1    Serrero, G.2
  • 6
    • 0030724392 scopus 로고    scopus 로고
    • Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein
    • Brasaemle D.L., Barber T., Wolins N.E., Serrero G., Blanchette-Mackie E.J., and Londos C. Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein. J Lipid Res 38 (1997) 2249-2263
    • (1997) J Lipid Res , vol.38 , pp. 2249-2263
    • Brasaemle, D.L.1    Barber, T.2    Wolins, N.E.3    Serrero, G.4    Blanchette-Mackie, E.J.5    Londos, C.6
  • 7
    • 0031733596 scopus 로고    scopus 로고
    • Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases
    • Heid H.W., Moll R., Schwetlick I., Rackwitz H.R., and Keenan T.W. Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res 294 (1998) 309-321
    • (1998) Cell Tissue Res , vol.294 , pp. 309-321
    • Heid, H.W.1    Moll, R.2    Schwetlick, I.3    Rackwitz, H.R.4    Keenan, T.W.5
  • 8
    • 0033546310 scopus 로고    scopus 로고
    • Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake
    • Gao J., and Serrero G. Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake. J Biol Chem 274 (1999) 16825-16830
    • (1999) J Biol Chem , vol.274 , pp. 16825-16830
    • Gao, J.1    Serrero, G.2
  • 12
    • 33646863002 scopus 로고    scopus 로고
    • PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver
    • Dalen K.T., Ulven S.M., Arntsen B.M., Solaas K., and Nebb H.I. PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver. J Lipid Res 47 (2006) 931-943
    • (2006) J Lipid Res , vol.47 , pp. 931-943
    • Dalen, K.T.1    Ulven, S.M.2    Arntsen, B.M.3    Solaas, K.4    Nebb, H.I.5
  • 15
    • 33745942915 scopus 로고    scopus 로고
    • Adipocyte differentiation-related protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low-density lipoproteins
    • Magnusson B., Asp L., Bostrom P., Ruiz M., Stillemark-Billton P., Linden D., Boren J., and Olofsson S.O. Adipocyte differentiation-related protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low-density lipoproteins. Arterioscler Thromb Vasc Biol 26 (2006) 1566-1571
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1566-1571
    • Magnusson, B.1    Asp, L.2    Bostrom, P.3    Ruiz, M.4    Stillemark-Billton, P.5    Linden, D.6    Boren, J.7    Olofsson, S.O.8
  • 16
    • 31344437783 scopus 로고    scopus 로고
    • Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein
    • Chang B.H., Li L., Paul A., Taniguchi S., Nannegari V., Heird W.C., and Chan L. Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein. Mol Cell Biol 26 (2006) 1063-1076
    • (2006) Mol Cell Biol , vol.26 , pp. 1063-1076
    • Chang, B.H.1    Li, L.2    Paul, A.3    Taniguchi, S.4    Nannegari, V.5    Heird, W.C.6    Chan, L.7
  • 17
    • 33846011095 scopus 로고    scopus 로고
    • Functional compensation for adipose differentiation-related protein (ADFP) by TIP47 in an adfp null embryonic cell line
    • Sztalryd C., Bell M., Lu X., Mertz P., Hickenbottom S., Chang B.H., Chan L., Kimmel A.R., and Londos C. Functional compensation for adipose differentiation-related protein (ADFP) by TIP47 in an adfp null embryonic cell line. J Biol Chem 281 (2006) 34341-34348
    • (2006) J Biol Chem , vol.281 , pp. 34341-34348
    • Sztalryd, C.1    Bell, M.2    Lu, X.3    Mertz, P.4    Hickenbottom, S.5    Chang, B.H.6    Chan, L.7    Kimmel, A.R.8    Londos, C.9
  • 18
    • 0036875212 scopus 로고    scopus 로고
    • Divergent effects of leptin in mice susceptible or resistant to obesity
    • Takahashi N., Patel H.R., Qi Y., Dushay J., and Ahima R.S. Divergent effects of leptin in mice susceptible or resistant to obesity. Horm Metab Res 34 (2002) 691-697
    • (2002) Horm Metab Res , vol.34 , pp. 691-697
    • Takahashi, N.1    Patel, H.R.2    Qi, Y.3    Dushay, J.4    Ahima, R.S.5
  • 19
    • 4344566976 scopus 로고    scopus 로고
    • A novel aminosterol reverses diabetes and fatty liver disease in obese mice
    • Takahashi N., Qi Y., Patel H.R., and Ahima R.S. A novel aminosterol reverses diabetes and fatty liver disease in obese mice. J Hepatol 41 (2004) 391-398
    • (2004) J Hepatol , vol.41 , pp. 391-398
    • Takahashi, N.1    Qi, Y.2    Patel, H.R.3    Ahima, R.S.4
  • 23
    • 20544474017 scopus 로고    scopus 로고
    • An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis
    • Crooke R.M., Graham M.J., Lemonidis K.M., Whipple C.P., Koo S., and Perera R.J. An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis. J Lipid Res 46 (2005) 872-884
    • (2005) J Lipid Res , vol.46 , pp. 872-884
    • Crooke, R.M.1    Graham, M.J.2    Lemonidis, K.M.3    Whipple, C.P.4    Koo, S.5    Perera, R.J.6
  • 25
    • 24344490760 scopus 로고    scopus 로고
    • Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339
    • Millar J.S., Cromley D.A., McCoy M.G., Rader D.J., and Billheimer J.T. Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339. J Lipid Res 46 (2005) 2023-2028
    • (2005) J Lipid Res , vol.46 , pp. 2023-2028
    • Millar, J.S.1    Cromley, D.A.2    McCoy, M.G.3    Rader, D.J.4    Billheimer, J.T.5
  • 26
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • Cai D., Yuan M., Frantz D.F., Melendez P.A., Hansen L., Lee J., and Shoelson S.E. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 11 (2005) 183-190
    • (2005) Nat Med , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5    Lee, J.6    Shoelson, S.E.7
  • 27
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 31
    • 33749058310 scopus 로고    scopus 로고
    • A proposed model of fat packaging by exchangeable lipid droplet proteins
    • Wolins N.E., Brasaemle D.L., and Bickel P.E. A proposed model of fat packaging by exchangeable lipid droplet proteins. FEBS Lett 580 (2006) 5484-5491
    • (2006) FEBS Lett , vol.580 , pp. 5484-5491
    • Wolins, N.E.1    Brasaemle, D.L.2    Bickel, P.E.3
  • 34
    • 4143094816 scopus 로고    scopus 로고
    • Metabolic adaptations in the absence of perilipin: increased beta-oxidation and decreased hepatic glucose production associated with peripheral insulin resistance but normal glucose tolerance in perilipin-null mice
    • Saha P.K., Kojima H., Martinez-Botas J., Sunehag A.L., and Chan L. Metabolic adaptations in the absence of perilipin: increased beta-oxidation and decreased hepatic glucose production associated with peripheral insulin resistance but normal glucose tolerance in perilipin-null mice. J Biol Chem 279 (2004) 35150-35158
    • (2004) J Biol Chem , vol.279 , pp. 35150-35158
    • Saha, P.K.1    Kojima, H.2    Martinez-Botas, J.3    Sunehag, A.L.4    Chan, L.5
  • 36
    • 18044388542 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase as a new drug target for obesity treatment
    • Dobrzyn A., and Ntambi J.M. Stearoyl-CoA desaturase as a new drug target for obesity treatment. Obes Rev 6 (2005) 169-174
    • (2005) Obes Rev , vol.6 , pp. 169-174
    • Dobrzyn, A.1    Ntambi, J.M.2
  • 37
    • 33745212925 scopus 로고    scopus 로고
    • Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance
    • Gutierrez-Juarez R., Pocai A., Mulas C., Ono H., Bhanot S., Monia B.P., and Rossetti L. Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance. J Clin Invest 116 (2006) 1686-1695
    • (2006) J Clin Invest , vol.116 , pp. 1686-1695
    • Gutierrez-Juarez, R.1    Pocai, A.2    Mulas, C.3    Ono, H.4    Bhanot, S.5    Monia, B.P.6    Rossetti, L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.