Intrarenal renin-angiotensin system mediates fatty acid-induced ER stress in the kidney

American Journal of Physiology - Renal Physiology

Volumn 310, Issue 5, 2016, Pages F351-F363

  Li, Chunling ^a   Lin, Yu ^a   Luo, Renfei ^a   Chen, Shaoming ^b   Wang, Feifei ^a   Zheng, Peili ^a   Levi, Moshe ^c   Yang, Tianxin ^a,d   Wang, Weidong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Angiotensin II; Kidney; Saturated fatty acid; Valsartan

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ALISKIREN; ANGIOTENSIN II; CASPASE 3; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; INOSITOL REQUIRING PROTEIN 1ALPHA; KIDNEY INJURY MOLECULE 1; MESSENGER RNA; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PALMITIC ACID; PROTEIN; RENIN; TUNICAMYCIN; UNCLASSIFIED DRUG; VALSARTAN; AMIDE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; DDIT3 PROTEIN, HUMAN; DDIT3 PROTEIN, MOUSE; FUMARIC ACID DERIVATIVE; GLUCOSE BLOOD LEVEL; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KIDNEY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE DAMAGE; LIPID DIET; MALE; METABOLIC PARAMETERS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ANIMAL; BLOOD; C57BL MOUSE; CELL LINE; CELL SURVIVAL; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE BLOOD LEVEL; KIDNEY DISEASES; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; URINE;

AMIDES; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CELL LINE; CELL SURVIVAL; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM STRESS; FUMARATES; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HUMANS; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; MALE; MICE, INBRED C57BL; PALMITIC ACID; RENIN-ANGIOTENSIN SYSTEM; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP; TUNICAMYCIN; UNFOLDED PROTEIN RESPONSE; VALSARTAN;

EID: 84983745330     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00223.2015     Document Type: Article

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