α-Linolenic acid protects renal cells against palmitic acid lipotoxicity via inhibition of endoplasmic reticulum stress

European Journal of Pharmacology

Volumn 623, Issue 1-3, 2009, Pages 107-112

  Katsoulieris, Elias ^a   Mabley, Jon G ^a   Samai, Mohamed ^b   Green, Irene C ^a   Chatterjee, Prabal K ^a  

^a School of Pharmacy and Biomolecular Sciences   (United Kingdom)

^b UNIVERSITY OF SIERRA LEONE   (Sierra Leone)

Author keywords

linolenic acid; Endoplasmic reticulum stress; Lipotoxicity; Oxidative stress; Palmitic acid; Renal proximal tubular cell

Indexed keywords

BETA ACTIN; FATTY ACID DERIVATIVE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; LINOLENIC ACID; PALMITIC ACID; PALMITOLEATE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; SALUBRINAL; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL LINE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GLYCOSYLATION; INHIBITION KINETICS; KIDNEY CELL; KIDNEY PROXIMAL TUBULE; LIPOTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; TOXICITY; WESTERN BLOTTING;

ALPHA-LINOLENIC ACID; ANIMALS; CELL DEATH; CELL LINE; CELL SURVIVAL; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; HEAT-SHOCK PROTEINS; KIDNEY TUBULES, PROXIMAL; PALMITIC ACID; PHOSPHORYLATION; RATS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTOR CHOP;

EID: 70350199601     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.09.015     Document Type: Article

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