-
1
-
-
0033597750
-
A vitamin D analog regulates mesangial cell smooth muscle phenotypes in a transforming growth factor-beta type II receptor-mediated manner
-
Abe H, Iehara N, Utsunomiya K, Kita T, Doi T. A vitamin D analog regulates mesangial cell smooth muscle phenotypes in a transforming growth factor-beta type II receptor-mediated manner. J Biol Chem 274: 20874-20878, 1999. (Pubitemid 129519584)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.30
, pp. 20874-20878
-
-
Abe, H.1
Iehara, N.2
Utsunomiya, K.3
Kita, T.4
Doi, T.5
-
2
-
-
16644396080
-
Overview: Obesity: What does it have to do with kidney disease?
-
Abrass CK. Overview: obesity: what does it have to do with kidney disease? J Am Soc Nephrol 15: 2768-2772, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2768-2772
-
-
Abrass, C.K.1
-
3
-
-
34250868932
-
Role of Kruppel-like transcription factors in endothelial biology
-
DOI 10.1161/01.RES.0000267856.00713.0a, PII 0000301220070622000004
-
Atkins GB, Jain MK. Role of Kruppel-like transcription factors in endothelial biology. Circ Res 100: 1686-1695, 2007. (Pubitemid 46987860)
-
(2007)
Circulation Research
, vol.100
, Issue.12
, pp. 1686-1695
-
-
Atkins, G.B.1
Jain, M.K.2
-
4
-
-
16644363689
-
Obesity-initiated metabolic syndrome and the kidney: A recipe for chronic kidney disease?
-
DOI 10.1097/01.ASN.0000141965.28037.EE
-
Bagby SP. Obesity-initiated metabolic syndrome and the kidney: a recipe for chronic kidney disease? J Am Soc Nephrol 15: 2775-2791, 2004. (Pubitemid 41103387)
-
(2004)
Journal of the American Society of Nephrology
, vol.15
, Issue.11
, pp. 2775-2791
-
-
Bagby, S.P.1
-
5
-
-
34249052234
-
TGF-beta in renal injury and disease
-
Bottinger EP. TGF-beta in renal injury and disease. Semin Nephrol 27: 309-320, 2007.
-
(2007)
Semin Nephrol
, vol.27
, pp. 309-320
-
-
Bottinger, E.P.1
-
6
-
-
0348226831
-
Diabetic Nephropathy and Transforming Growth Factor-beta: Transforming Our View of Glomerulosclerosis and Fibrosis Build-Up
-
Chen S, Jim B, Ziyadeh FN. Diabetic nephropathy and transforming growth factor-beta: transforming our view of glomerulosclerosis and fibrosis build-up. Semin Nephrol 23: 532-543, 2003. (Pubitemid 38030087)
-
(2003)
Seminars in Nephrology
, vol.23
, Issue.6
, pp. 532-543
-
-
Chen, S.1
Jim, B.2
Ziyadeh, F.N.3
-
7
-
-
33646685311
-
KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium
-
DOI 10.1182/blood-2005-08-3465
-
Dekker RJ, Boon RA, Rondaij MG, Kragt A, Volger OL, Elderkamp YW, Meijers JC, Voorberg J, Pannekoek H, Horrevoets AJ. KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium. Blood 107: 4354-4363, 2006. (Pubitemid 43801361)
-
(2006)
Blood
, vol.107
, Issue.11
, pp. 4354-4363
-
-
Dekker, R.J.1
Boon, R.A.2
Rondaij, M.G.3
Kragt, A.4
Volger, O.L.5
Elderkamp, Y.W.6
Meijers, J.C.M.7
Voorberg, J.8
Pannekoek, H.9
Horrevoets, A.J.G.10
-
8
-
-
0034711185
-
Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators
-
DOI 10.1074/jbc.M004045200
-
Delerive P, Gervois P, Fruchart JC, Staels B. Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators. J Biol Chem 275: 36703-36707, 2000. (Pubitemid 32002075)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.47
, pp. 36703-36707
-
-
Delerive, P.1
Gervois, P.2
Fruchart, J.-C.3
Staels, B.4
-
9
-
-
34548645095
-
Lipotoxic and inflammatory phenotypes in rats with uncontrolled metabolic syndrome and nephropathy
-
DOI 10.1152/ajprenal.00021.2007
-
Dominguez J, Wu P, Packer CS, Temm C, Kelly KJ. Lipotoxic and inflammatory phenotypes in rats with uncontrolled metabolic syndrome and nephropathy. Am J Physiol Renal Physiol 293: F670-F679, 2007. (Pubitemid 47403336)
-
(2007)
American Journal of Physiology - Renal Physiology
, vol.293
, Issue.3
-
-
Dominguez, J.H.1
Wu, P.2
Packer, C.S.3
Temm, C.4
Kelly, K.J.5
-
10
-
-
33745230441
-
Renal injury: Similarities and differences in male and female rats with the metabolic syndrome
-
Dominguez JH, Wu P, Hawes JW, Deeg M, Walsh J, Packer SC, Nagase M, Temm C, Goss E, Peterson R. Renal injury: similarities and differences in male and female rats with the metabolic syndrome. Kidney Int 69: 1969-1976, 2006.
-
(2006)
Kidney Int
, vol.69
, pp. 1969-1976
-
-
Dominguez, J.H.1
Wu, P.2
Hawes, J.W.3
Deeg, M.4
Walsh, J.5
Packer, S.C.6
Nagase, M.7
Temm, C.8
Goss, E.9
Peterson, R.10
-
11
-
-
1842527650
-
Glucose Regulates the Expression of the Farnesoid X Receptor in Liver
-
DOI 10.2337/diabetes.53.4.890
-
Duran-Sandoval D, Mautino G, Martin G, Percevault F, Barbier O, Fruchart JC, Kuipers F, Staels B. Glucose regulates the expression of the farnesoid X receptor in liver. Diabetes 53: 890-898, 2004. (Pubitemid 38436600)
-
(2004)
Diabetes
, vol.53
, Issue.4
, pp. 890-898
-
-
Duran-Sandoval, D.1
Mautino, G.2
Martin, G.3
Percevault, F.4
Barbier, O.5
Fruchart, J.-C.6
Kuipers, F.7
Staels, B.8
-
12
-
-
7644244675
-
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
-
DOI 10.1053/j.gastro.2004.08.001, PII S0016508504013903
-
Fiorucci S, Antonelli E, Rizzo G, Renga B, Mencarelli A, Riccardi L, Orlandi S, Pellicciari R, Morelli A. The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis. Gastroenterology 127: 1497-1512, 2004. (Pubitemid 39457775)
-
(2004)
Gastroenterology
, vol.127
, Issue.5
, pp. 1497-1512
-
-
Fiorucci, S.1
Antonelli, E.2
Rizzo, G.3
Renga, B.4
Mencarelli, A.5
Riccardi, L.6
Orlandi, S.7
Pellicciari, R.8
Morelli, A.9
-
13
-
-
4043060025
-
A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development
-
Giarratana N, Penna G, Amuchastegui S, Mariani R, Daniel KC, Adorini L. A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development. J Immunol 173: 2280-2287, 2004. (Pubitemid 39063083)
-
(2004)
Journal of Immunology
, vol.173
, Issue.4
, pp. 2280-2287
-
-
Giarratana, N.1
Penna, G.2
Amuchastegui, S.3
Mariani, R.4
Daniel, K.C.5
Adorini, L.6
-
14
-
-
0033637121
-
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
-
Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, Moore LB, Galardi C, Wilson JG, Lewis MC, Roth ME, Maloney PR, Willson TM, Kliewer SA. A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol Cell 6: 517-526, 2000.
-
(2000)
Mol Cell
, vol.6
, pp. 517-526
-
-
Goodwin, B.1
Jones, S.A.2
Price, R.R.3
Watson, M.A.4
McKee, D.D.5
Moore, L.B.6
Galardi, C.7
Wilson, J.G.8
Lewis, M.C.9
Roth, M.E.10
Maloney, P.R.11
Willson, T.M.12
Kliewer, S.A.13
-
15
-
-
30844436795
-
Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice
-
DOI 10.1194/jlr.M500390-JLR200
-
Hanniman EA, Lambert G, McCarthy TC, Sinal CJ. Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice. J Lipid Res 46: 2595-2604, 2005. (Pubitemid 43107471)
-
(2005)
Journal of Lipid Research
, vol.46
, Issue.12
, pp. 2595-2604
-
-
Hanniman, E.A.1
Lambert, G.2
McCarthy, T.C.3
Sinal, C.J.4
-
16
-
-
67650566600
-
Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice
-
Hartman HB, Gardell SJ, Petucci CJ, Wang S, Krueger JA, Evans MJ. Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice. J Lipid Res 50: 1090-1100, 2009.
-
(2009)
J Lipid Res
, vol.50
, pp. 1090-1100
-
-
Hartman, H.B.1
Gardell, S.J.2
Petucci, C.J.3
Wang, S.4
Krueger, J.A.5
Evans, M.J.6
-
17
-
-
0035017738
-
Functional and structural changes in the kidney in the early stages of obesity
-
Henegar JR, Bigler SA, Henegar LK, Tyagi SC, Hall JE. Functional and structural changes in the kidney in the early stages of obesity. J Am Soc Nephrol 12: 1211-1217, 2001.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 1211-1217
-
-
Henegar, J.R.1
Bigler, S.A.2
Henegar, L.K.3
Tyagi, S.C.4
Hall, J.E.5
-
18
-
-
0026000337
-
Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat
-
Iida H, Seifert R, Alpers CE, Gronwald RG, Phillips PE, Pritzl P, Gordon K, Gown AM, Ross R, Bowen-Pope DF, Johnson RJ. Plateletderived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat. Proc Natl Acad Sci USA 88: 6560-6564, 1991. (Pubitemid 21914987)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.15
, pp. 6560-6564
-
-
Iida, H.1
Seifert, R.2
Alpers, C.E.3
Gronwald, R.G.K.4
Phillips, P.E.5
Pritzl, P.6
Gordon, K.7
Gown, A.M.8
Ross, R.9
Bowen-Pope, D.F.10
Johnson, R.J.11
-
19
-
-
45249108429
-
Proteinuria in diabetic kidney disease: A mechanistic viewpoint
-
DOI 10.1038/ki.2008.128, PII KI2008128
-
Jefferson JA, Shankland SJ, Pichler RH. Proteinuria in diabetic kidney disease: a mechanistic viewpoint. Kidney Int 74: 22-36, 2008. (Pubitemid 351841893)
-
(2008)
Kidney International
, vol.74
, Issue.1
, pp. 22-36
-
-
Jefferson, J.A.1
Shankland, S.J.2
Pichler, R.H.3
-
20
-
-
32844473528
-
Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease
-
DOI 10.1111/j.1523-1755.2005.00733.x, PII 4495606
-
Jiang T, Liebman SE, Lucia MS, Li J, Levi M. Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease. Kidney Int 68: 2608-2620, 2005. (Pubitemid 43251007)
-
(2005)
Kidney International
, vol.68
, Issue.6
, pp. 2608-2620
-
-
Jiang, T.1
Liebman, S.E.2
Lucia, M.S.3
Li, J.4
Levi, M.5
-
21
-
-
28444434745
-
Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease
-
DOI 10.1681/ASN.2004080701
-
Jiang T, Liebman SE, Lucia MS, Phillips CL, Levi M. Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease. J Am Soc Nephrol 16: 2385-2394, 2005. (Pubitemid 41725056)
-
(2005)
Journal of the American Society of Nephrology
, vol.16
, Issue.8
, pp. 2385-2394
-
-
Jiang, T.1
Liebman, S.E.2
Lucia, M.S.3
Phillips, C.L.4
Levi, M.5
-
22
-
-
34948838912
-
Farnesoid X receptor modulates renal lipid metabolism, fibrosis, and diabetic nephropathy
-
DOI 10.2337/db06-1642
-
Jiang T, Wang XX, Scherzer P, Wilson P, Tallman J, Takahashi H, Li J, Iwahashi M, Sutherland E, Arend L, Levi M. Farnesoid X receptor modulates renal lipid metabolism, fibrosis, and diabetic nephropathy. Diabetes 56: 2485-2493, 2007. (Pubitemid 47523255)
-
(2007)
Diabetes
, vol.56
, Issue.10
, pp. 2485-2493
-
-
Jiang, T.1
Wang, X.X.2
Scherzer, P.3
Wilson, P.4
Tallman, J.5
Takahashi, H.6
Li, J.7
Iwahashi, M.8
Sutherland, E.9
Arend, L.10
Levi, M.11
-
23
-
-
25444465657
-
Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway
-
DOI 10.1074/jbc.M500801200
-
Jiang T, Wang Z, Proctor G, Moskowitz S, Liebman SE, Rogers T, Lucia MS, Li J, Levi M. Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway. J Biol Chem 280: 32317-32325, 2005. (Pubitemid 41361841)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.37
, pp. 32317-32325
-
-
Jiang, T.1
Wang, Z.2
Proctor, G.3
Moskowitz, S.4
Liebman, S.E.5
Rogers, T.6
Lucia, M.S.7
Li, J.8
Levi, M.9
-
24
-
-
0035071325
-
Obesity-related glomerulopathy: An emerging epidemic
-
Kambham N, Markowitz GS, Valeri AM, Lin J, D'Agati VD. Obesity-related glomerulopathy: an emerging epidemic. Kidney Int 59: 1498-1509, 2001.
-
(2001)
Kidney Int
, vol.59
, pp. 1498-1509
-
-
Kambham, N.1
Markowitz, G.S.2
Valeri, A.M.3
Lin, J.4
D'Agati, V.D.5
-
25
-
-
34948821093
-
Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet
-
DOI 10.1681/ASN.2007010089
-
Kume S, Uzu T, Araki S, Sugimoto T, Isshiki K, Chin-Kanasaki M, Sakaguchi M, Kubota N, Terauchi Y, Kadowaki T, Haneda M, Kashiwagi A, Koya D. Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet. J Am Soc Nephrol 18: 2715-2723, 2007. (Pubitemid 47531198)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.10
, pp. 2715-2723
-
-
Kume, S.1
Uzu, T.2
Araki, S.-I.3
Sugimoto, T.4
Isshiki, K.5
Chin-Kanasaki, M.6
Sakaguchi, M.7
Kubota, N.8
Terauchi, Y.9
Kadowaki, T.10
Haneda, M.11
Kashiwagi, A.12
Koya, D.13
-
26
-
-
36349013143
-
Farnesoid X receptor ligands inhibit vascular smooth muscle cell inflammation and migration
-
DOI 10.1161/ATVBAHA.107.152694, PII 0004360520071200000018
-
Li YT, Swales KE, Thomas GJ, Warner TD, Bishop-Bailey D. Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration. Arterioscler Thromb Vasc Biol 27: 2606-2611, 2007. (Pubitemid 350158912)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.12
, pp. 2606-2611
-
-
Li, Y.T.Y.1
Swales, K.E.2
Thomas, G.J.3
Warner, T.D.4
Bishop-Bailey, D.5
-
28
-
-
33645509321
-
Farnesoid X receptor is essential for normal glucose homeostasis
-
Ma K, Saha PK, Chan L, Moore DD. Farnesoid X receptor is essential for normal glucose homeostasis. J Clin Invest 116: 1102-1109, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 1102-1109
-
-
Ma, K.1
Saha, P.K.2
Chan, L.3
Moore, D.D.4
-
29
-
-
0033591297
-
Identification of a nuclear receptor for bite acids
-
DOI 10.1126/science.284.5418.1362
-
Makishima M, Okamoto AY, Repa JJ, Tu H, Learned RM, Luk A, Hull MV, Lustig KD, Mangelsdorf DJ, Shan B. Identification of a nuclear receptor for bile acids. Science 284: 1362-1365, 1999. (Pubitemid 29289663)
-
(1999)
Science
, vol.284
, Issue.5418
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Learned, R.M.5
Luk, A.6
Hull, M.V.7
Lustig, K.D.8
Mangelsdorf, D.J.9
Shan, B.10
-
30
-
-
59649084903
-
Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development
-
Maran RR, Thomas A, Roth M, Sheng Z, Esterly N, Pinson D, Gao X, Zhang Y, Ganapathy V, Gonzalez FJ, Guo GL. Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development. J Pharmacol Exp Ther 328: 469-477, 2009.
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 469-477
-
-
Maran, R.R.1
Thomas, A.2
Roth, M.3
Sheng, Z.4
Esterly, N.5
Pinson, D.6
Gao, X.7
Zhang, Y.8
Ganapathy, V.9
Gonzalez, F.J.10
Guo, G.L.11
-
31
-
-
0030816323
-
Synaptopodin: An actin-associated protein in telencephalic dendrites and renal podocytes
-
DOI 10.1083/jcb.139.1.193
-
Mundel P, Heid HW, Mundel TM, Kruger M, Reiser J, Kriz W. Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes. J Cell Biol 139: 193-204, 1997. (Pubitemid 27444091)
-
(1997)
Journal of Cell Biology
, vol.139
, Issue.1
, pp. 193-204
-
-
Mundel, P.1
Heid, H.W.2
Mundel, T.M.3
Kruger, M.4
Reiser, J.5
Kriz, W.6
-
32
-
-
31044453008
-
Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2
-
DOI 10.1172/JCI24787
-
Parmar KM, Larman HB, Dai G, Zhang Y, Wang ET, Moorthy SN, Kratz JR, Lin Z, Jain MK, Gimbrone MA Jr, Garcia-Cardena G. Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2. J Clin Invest 116: 49-58, 2006. (Pubitemid 43121790)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.1
, pp. 49-58
-
-
Parmar, K.M.1
Larman, H.B.2
Dai, G.3
Zhang, Y.4
Wang, E.T.5
Moorthy, S.N.6
Kratz, J.R.7
Lin, Z.8
Jain, M.K.9
Gimbrone Jr., M.A.10
Garcia-Cardena, G.11
-
33
-
-
0037101810
-
6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity
-
DOI 10.1021/jm025529g
-
Pellicciari R, Fiorucci S, Camaioni E, Clerici C, Costantino G, Maloney PR, Morelli A, Parks DJ, Willson TM. 6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. J Med Chem 45: 3569-3572, 2002. (Pubitemid 34856095)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.17
, pp. 3569-3572
-
-
Pellicciari, R.1
Fiorucci, S.2
Camaioni, E.3
Clerici, C.4
Costantino, G.5
Maloney, P.R.6
Morelli, A.7
Parks, D.J.8
Willson, T.M.9
-
34
-
-
0036020935
-
Obesity-A neglected culprit in renal disease
-
Praga M. Obesity - a neglected culprit in renal disease. Nephrol Dial Transplant 17: 1157-1159, 2002. (Pubitemid 34812055)
-
(2002)
Nephrology Dialysis Transplantation
, vol.17
, Issue.7
, pp. 1157-1159
-
-
Praga, M.1
-
35
-
-
33747331935
-
Obesity, proteinuria and progression of renal failure
-
DOI 10.1097/01.mnh.0000242172.06459.7c, PII 0004155220060900000003
-
Praga M, Morales E. Obesity, proteinuria and progression of renal failure. Curr Opin Nephrol Hypertens 15: 481-486, 2006. (Pubitemid 44246397)
-
(2006)
Current Opinion in Nephrology and Hypertension
, vol.15
, Issue.5
, pp. 481-486
-
-
Praga, M.1
Morales, E.2
-
36
-
-
33750580307
-
Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes
-
DOI 10.2337/db05-0603
-
Proctor G, Jiang T, Iwahashi M, Wang Z, Li J, Levi M. Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes. Diabetes 55: 2502-2509, 2006. (Pubitemid 44871150)
-
(2006)
Diabetes
, vol.55
, Issue.9
, pp. 2502-2509
-
-
Proctor, G.1
Jiang, T.2
Iwahashi, M.3
Wang, Z.4
Li, J.5
Levi, M.6
-
37
-
-
24144496134
-
Characterization of susceptibility of inbred mouse strains to diabetic nephropathy
-
DOI 10.2337/diabetes.54.9.2628
-
Qi Z, Fujita H, Jin J, Davis LS, Wang Y, Fogo AB, Breyer MD. Characterization of susceptibility of inbred mouse strains to diabetic nephropathy. Diabetes 54: 2628-2637, 2005. (Pubitemid 41233584)
-
(2005)
Diabetes
, vol.54
, Issue.9
, pp. 2628-2637
-
-
Qi, Z.1
Fujita, H.2
Jin, J.3
Davis, L.S.4
Wang, Y.5
Fogo, A.B.6
Breyer, M.D.7
-
38
-
-
48249127629
-
From fibrosis to sclerosis: Mechanisms of glomerulosclerosis in diabetic nephropathy
-
Qian Y, Feldman E, Pennathur S, Kretzler M, Brosius FC III. From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy. Diabetes 57: 1439-1445, 2008.
-
(2008)
Diabetes
, vol.57
, pp. 1439-1445
-
-
Qian, Y.1
Feldman, E.2
Pennathur, S.3
Kretzler, M.4
Brosius III, F.C.5
-
39
-
-
0036317545
-
Deconstructing and reconstructing obesity-induced diabetes (diabesity) in mice
-
Reifsnyder PC, Leiter EH. Deconstructing and reconstructing obesity-induced diabetes (diabesity) in mice. Diabetes 51: 825-832, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 825-832
-
-
Reifsnyder, P.C.1
Leiter, E.H.2
-
40
-
-
2542500709
-
KLF2 is a novel transcriptional regulator of endothelial proinflammatory activation
-
DOI 10.1084/jem.20031132
-
SenBanerjee S, Lin Z, Atkins GB, Greif DM, Rao RM, Kumar A, Feinberg MW, Chen Z, Simon DI, Luscinskas FW, Michel TM, Gimbrone MA Jr, Garcia-Cardena G, Jain MK. KLF2 is a novel transcriptional regulator of endothelial proinflammatory activation. J Exp Med 199: 1305-1315, 2004. (Pubitemid 38685723)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.10
, pp. 1305-1315
-
-
Senbanerjee, S.1
Lin, Z.2
Atkins, G.B.3
Greif, D.M.4
Rao, R.M.5
Kumar, A.6
Feinberg, M.W.7
Chen, Z.8
Simon, D.I.9
Luscinskas, F.W.10
Michel, T.M.11
Gimbrone Jr., M.A.12
Garcia-Cardena, G.13
Jain, M.K.14
-
41
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal CJ, Tohkin M, Miyata M, Ward JM, Lambert G, Gonzalez FJ. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102: 731-744, 2000.
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
Tohkin, M.2
Miyata, M.3
Ward, J.M.4
Lambert, G.5
Gonzalez, F.J.6
-
42
-
-
14244264780
-
Regulation of carbohydrate metabolism by the farnesoid X receptor
-
DOI 10.1210/en.2004-0965
-
Stayrook KR, Bramlett KS, Savkur RS, Ficorilli J, Cook T, Christe ME, Michael LF, Burris TP. Regulation of carbohydrate metabolism by the farnesoid X receptor. Endocrinology 146: 984-991, 2005. (Pubitemid 40289284)
-
(2005)
Endocrinology
, vol.146
, Issue.3
, pp. 984-991
-
-
Stayrook, K.R.1
Bramlett, K.S.2
Savkur, R.S.3
Ficorilli, J.4
Cook, T.5
Christe, M.E.6
Michael, L.F.7
Burris, T.P.8
-
43
-
-
33750712380
-
Renal fibroblasts and myofibroblasts in chronic kidney disease
-
DOI 10.1681/ASN.2006050420
-
Strutz F, Zeisberg M. Renal fibroblasts and myofibroblasts in chronic kidney disease. J Am Soc Nephrol 17: 2992-2998, 2006. (Pubitemid 44707759)
-
(2006)
Journal of the American Society of Nephrology
, vol.17
, Issue.11
, pp. 2992-2998
-
-
Strutz, F.1
Zeisberg, M.2
-
44
-
-
0037166338
-
Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus
-
DOI 10.1074/jbc.M110650200
-
Sun L, Halaihel N, Zhang W, Rogers T, Levi M. Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus. J Biol Chem 277: 18919-18927, 2002. (Pubitemid 34952453)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.21
, pp. 18919-18927
-
-
Sun, L.1
Halaihel, N.2
Zhang, W.3
Rogers, H.4
Levi, M.5
-
45
-
-
48749113401
-
Targeting bile-acid signalling for metabolic diseases
-
Thomas C, Pellicciari R, Pruzanski M, Auwerx J, Schoonjans K. Targeting bile-acid signalling for metabolic diseases. Nat Rev Drug Discov 7: 678-693, 2008.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 678-693
-
-
Thomas, C.1
Pellicciari, R.2
Pruzanski, M.3
Auwerx, J.4
Schoonjans, K.5
-
46
-
-
38149090050
-
How do mesangial and endothelial cells form the glomerular tuft?
-
Vaughan MR, Quaggin SE. How do mesangial and endothelial cells form the glomerular tuft? J Am Soc Nephrol 19: 24-33, 2008.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 24-33
-
-
Vaughan, M.R.1
Quaggin, S.E.2
-
47
-
-
34748828509
-
Obesity and obesity-initiated metabolic syndrome: Mechanistic links to chronic kidney disease
-
Wahba IM, Mak RH. Obesity and obesity-initiated metabolic syndrome: mechanistic links to chronic kidney disease. Clin J Am Soc Nephrol 2: 550-562, 2007.
-
(2007)
Clin J Am Soc Nephrol
, vol.2
, pp. 550-562
-
-
Wahba, I.M.1
Mak, R.H.2
-
48
-
-
37249003426
-
Association between obesity and kidney disease: A systematic review and meta-analysis
-
DOI 10.1038/sj.ki.5002586, PII 5002586
-
Wang Y, Chen X, Song Y, Caballero B, Cheskin LJ. Association between obesity and kidney disease: a systematic review and metaanalysis. Kidney Int 73: 19-33, 2008. (Pubitemid 350273639)
-
(2008)
Kidney International
, vol.73
, Issue.1
, pp. 19-33
-
-
Wang, Y.1
Chen, X.2
Song, Y.3
Caballero, B.4
Cheskin, L.J.5
-
49
-
-
23644438916
-
db/db mice with type 2 diabetes
-
DOI 10.2337/diabetes.54.8.2328
-
Wang Z, Jiang T, Li J, Proctor G, McManaman JL, Lucia S, Chua S, Levi M. Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes. Diabetes 54: 2328-2335, 2005. (Pubitemid 41134259)
-
(2005)
Diabetes
, vol.54
, Issue.8
, pp. 2328-2335
-
-
Wang, Z.1
Jiang, T.2
Li, J.3
Proctor, G.4
McManaman, J.L.5
Lucia, S.6
Chua, S.7
Levi, M.8
-
50
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
DOI 10.1038/nature04330, PII NATURE04330
-
Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, Messaddeq N, Harney JW, Ezaki O, Kodama T, Schoonjans K, Bianco AC, Auwerx J. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 439: 484-489, 2006. (Pubitemid 43152840)
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
Christoffolete, M.A.4
Kim, B.W.5
Sato, H.6
Messaddeq, N.7
Harney, J.W.8
Ezaki, O.9
Kodama, T.10
Schoonjans, K.11
Bianco, A.C.12
Auwerx, J.13
-
51
-
-
85047694456
-
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
-
DOI 10.1172/JCI200421025
-
Watanabe M, Houten SM, Wang L, Moschetta A, Mangelsdorf DJ, Heyman RA, Moore DD, Auwerx J. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J Clin Invest 113: 1408-1418, 2004. (Pubitemid 39071696)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.10
, pp. 1408-1418
-
-
Watanabe, M.1
Houten, S.M.2
Wang, L.3
Moschetta, A.4
Mangelsdorf, D.J.5
Heyman, R.A.6
Moore, D.D.7
Auwerx, J.8
-
52
-
-
16244381893
-
The inflammatory syndrome: The role of adipose tissue cytokines in metabolic disorders linked to obesity
-
Wisse BE. The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity. J Am Soc Nephrol 15: 2792-2800, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2792-2800
-
-
Wisse, B.E.1
-
53
-
-
29344466239
-
Obesity-related glomerulopathy: Insights from gene expression profiles of the glomeruli derived from renal biopsy samples
-
DOI 10.1210/en.2005-0641
-
Wu Y, Liu Z, Xiang Z, Zeng C, Chen Z, Ma X, Li L. Obesity-related glomerulopathy: insights from gene expression profiles of the glomeruli derived from renal biopsy samples. Endocrinology 147: 44-50, 2006. (Pubitemid 43004261)
-
(2006)
Endocrinology
, vol.147
, Issue.1
, pp. 44-50
-
-
Wu, Y.1
Liu, Z.2
Xiang, Z.3
Zeng, C.4
Chen, Z.5
Ma, X.6
Li, L.7
-
54
-
-
0942279602
-
Peroxisome proliferator-activated receptor-alpha coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR
-
DOI 10.1101/gad.1138104
-
Zhang Y, Castellani LW, Sinal CJ, Gonzalez FJ, Edwards PA. Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC- 1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR. Genes Dev 18: 157-169, 2004. (Pubitemid 38141784)
-
(2004)
Genes and Development
, vol.18
, Issue.2
, pp. 157-169
-
-
Zhang, Y.1
Castellani, L.W.2
Sinal, C.J.3
Gonzalez, F.J.4
Edwards, P.A.5
-
55
-
-
32244447570
-
Activation of the nuclear FXR improves hyperglycemia and hyperlipidemia in diabetic mice
-
DOI 10.1073/pnas.0506982103
-
Zhang Y, Lee FY, Barrera G, Lee H, Vales C, Gonzalez FJ, Willson TM, Edwards PA. Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. Proc Natl Acad Sci USA 103: 1006-1011, 2006. (Pubitemid 43212212)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.4
, pp. 1006-1011
-
-
Zhang, Y.1
Lee, F.Y.2
Barrera, G.3
Lee, H.4
Vales, C.5
Gonzalez, F.J.6
Willson, T.M.7
Edwards, P.A.8
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