REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling

Science Signaling

Volumn 7, Issue 335, 2014, Pages

  Dennis, Michael D ^a   Coleman, Catherine S ^a   Berg, Arthur ^a   Jefferson, Leonard S ^a   Kimball, Scot R ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; REGULATED IN DNA DAMAGE AND DEVELOPMENT 1 PROTEIN; REPRESSOR PROTEIN; RHEB PROTEIN; TUBERIN; UNCLASSIFIED DRUG; DDIT4 PROTEIN, HUMAN; DDIT4 PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PHOSPHOPROTEIN PHOSPHATASE 2; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; FIBROBLAST; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANIMAL; GENETICS; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; FIBROBLASTS; HEK293 CELLS; HUMANS; MICE; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS;

EID: 84906833417     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005103     Document Type: Article

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