β-Blocker carvedilol protects cardiomyocytes against oxidative stress-induced apoptosis by up-regulating miR-133 expression

Journal of Molecular and Cellular Cardiology

Volumn 75, Issue , 2014, Pages 111-121

  Xu, Chaoqian ^a   Hu, Yingying ^a   Hou, Liangyu ^a   Ju, Jin ^a   Li, Xiaoguang ^a   Du, Ning ^a   Guan, Xiaoxiang ^a   Liu, Zhenhong ^a   Zhang, Tianze ^b   Qin, Wei ^a   Shen, Nannan ^a   Bilal, Muhammad U ^a   Lu, Yanjie ^a   Zhang, Yong ^a   Shan, Hongli ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Carvedilol; Caspase 3; Caspase 9; MiR 133; Oxidative stress

Indexed keywords

CARVEDILOL; CASPASE 3; CASPASE 9; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MALONALDEHYDE; MICRORNA; MICRORNA 133; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARBAZOLE DERIVATIVE; CARDIOTONIC AGENT; MIRN133 MICRORNA, RAT; PROPANOLAMINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HEART INFARCTION; HEART MUSCLE CELL; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; MALE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; UPREGULATION; ANIMAL; DRUG EFFECTS; ENZYMOLOGY; GENE SILENCING; GENETICS; HEART FUNCTION TEST; METABOLISM; MYOCARDIAL INFARCTION; PATHOLOGY; WISTAR RAT;

RATTUS;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; APOPTOSIS; CARBAZOLES; CARDIOTONIC AGENTS; CASPASE 9; CYTOPROTECTION; GENE KNOCKDOWN TECHNIQUES; HEART FUNCTION TESTS; HYDROGEN PEROXIDE; MALE; MICRORNAS; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PROPANOLAMINES; RATS, WISTAR; UP-REGULATION;

EID: 84907497918     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.07.009     Document Type: Article

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