-
1
-
-
0019811465
-
Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences
-
Banerji J, Rusconi S, Schaffner W. 1981. Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell 27: 299–308.
-
(1981)
Cell
, vol.27
, pp. 299-308
-
-
Banerji, J.1
Rusconi, S.2
Schaffner, W.3
-
2
-
-
84875156063
-
Enhancers: five essential questions
-
Pennacchio LA, Bickmore W, Dean A, Nobrega MA, et al. 2013. Enhancers: five essential questions. Nat Rev Genet 14: 288–95.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 288-295
-
-
Pennacchio, L.A.1
Bickmore, W.2
Dean, A.3
Nobrega, M.A.4
-
3
-
-
84897459814
-
An atlas of active enhancers across human cell types and tissues
-
Andersson R, Gebhard C, Miguel-Escalada I, Hoof I, et al. 2014. An atlas of active enhancers across human cell types and tissues. Nature 507: 455–61.
-
(2014)
Nature
, vol.507
, pp. 455-461
-
-
Andersson, R.1
Gebhard, C.2
Miguel-Escalada, I.3
Hoof, I.4
-
4
-
-
84928017429
-
Enhancer variants: evaluating functions in common disease
-
Corradin O, Scacheri PC. 2014. Enhancer variants: evaluating functions in common disease. Genome Med 6: 85.
-
(2014)
Genome Med
, vol.6
, pp. 85
-
-
Corradin, O.1
Scacheri, P.C.2
-
5
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, et al. 2009. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 106: 9362–7.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
-
7
-
-
84865249952
-
Transcription factors: from enhancer binding to developmental control
-
Spitz F, Furlong EEM. 2012. Transcription factors: from enhancer binding to developmental control. Nat Rev Genet 13: 613–26.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 613-626
-
-
Spitz, F.1
Furlong, E.E.M.2
-
8
-
-
0037188510
-
Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly
-
Lettice LA, Horikoshi T, Heaney SJH, van Baren MJ, et al. 2002. Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly. Proc Natl Acad Sci USA 99: 7548–53.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7548-7553
-
-
Lettice, L.A.1
Horikoshi, T.2
Heaney, S.J.H.3
van Baren, M.J.4
-
9
-
-
0025292742
-
The beta-globin dominant control region: hypersensitive site 2
-
Philipsen S, Talbot D, Fraser P, Grosveld F. 1990. The beta-globin dominant control region: hypersensitive site 2. EMBO J 9: 2159–67.
-
(1990)
EMBO J
, vol.9
, pp. 2159-2167
-
-
Philipsen, S.1
Talbot, D.2
Fraser, P.3
Grosveld, F.4
-
10
-
-
0025365230
-
Detailed analysis of the site 3 region of the human beta-globin dominant control region
-
Talbot D, Philipsen S, Fraser P, Grosveld F. 1990. Detailed analysis of the site 3 region of the human beta-globin dominant control region. EMBO J 9: 2169–77.
-
(1990)
EMBO J
, vol.9
, pp. 2169-2177
-
-
Talbot, D.1
Philipsen, S.2
Fraser, P.3
Grosveld, F.4
-
11
-
-
0029294548
-
A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation
-
Roberts SG, Choy B, Walker SS, Lin YS, et al. 1995. A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation. Curr Biol 5: 508–16.
-
(1995)
Curr Biol
, vol.5
, pp. 508-516
-
-
Roberts, S.G.1
Choy, B.2
Walker, S.S.3
Lin, Y.S.4
-
12
-
-
0030943297
-
Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain
-
Fry CJ, Slansky JE, Farnham PJ. 1997. Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain. Mol Cell Biol 17: 1966–76.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1966-1976
-
-
Fry, C.J.1
Slansky, J.E.2
Farnham, P.J.3
-
13
-
-
34547147926
-
Analysis of transcriptional activation at a distance in Saccharomyces cerevisiae
-
Dobi KC, Winston F. 2007. Analysis of transcriptional activation at a distance in Saccharomyces cerevisiae. Mol Cell Biol 27: 5575–86.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 5575-5586
-
-
Dobi, K.C.1
Winston, F.2
-
14
-
-
84943654279
-
Analysis of polygenic mutants suggests a role for mediator in regulating transcriptional activation distance in Saccharomyces cerevisiae
-
Reavey CT, Hickman MJ, Dobi KC, Botstein D, et al. 2015. Analysis of polygenic mutants suggests a role for mediator in regulating transcriptional activation distance in Saccharomyces cerevisiae. Genetics 201: 599–612.
-
(2015)
Genetics
, vol.201
, pp. 599-612
-
-
Reavey, C.T.1
Hickman, M.J.2
Dobi, K.C.3
Botstein, D.4
-
15
-
-
0027052876
-
Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions
-
Seipel K, Georgiev O, Schaffner W. 1992. Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions. EMBO J 11: 4961–8.
-
(1992)
EMBO J
, vol.11
, pp. 4961-4968
-
-
Seipel, K.1
Georgiev, O.2
Schaffner, W.3
-
16
-
-
84911494217
-
Principles of regulatory information conservation between mouse and human
-
Cheng Y, Ma Z, Kim B-H, Wu W, et al. 2014. Principles of regulatory information conservation between mouse and human. Nature 515: 371–5.
-
(2014)
Nature
, vol.515
, pp. 371-375
-
-
Cheng, Y.1
Ma, Z.2
Kim, B.-H.3
Wu, W.4
-
17
-
-
0018732960
-
Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA
-
Weil PA, Luse DS, Segall J, Roeder RG. 1979. Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell 18: 469–84.
-
(1979)
Cell
, vol.18
, pp. 469-484
-
-
Weil, P.A.1
Luse, D.S.2
Segall, J.3
Roeder, R.G.4
-
18
-
-
33747881750
-
The general transcription machinery and general cofactors
-
Thomas MC, Chiang C-M. 2006. The general transcription machinery and general cofactors. Crit Rev Biochem Mol Biol 41: 105–78.
-
(2006)
Crit Rev Biochem Mol Biol
, vol.41
, pp. 105-178
-
-
Thomas, M.C.1
Chiang, C.-M.2
-
20
-
-
0028282551
-
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
-
Kim YJ, Björklund S, Li Y, Sayre MH, et al. 1994. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77: 599–608.
-
(1994)
Cell
, vol.77
, pp. 599-608
-
-
Kim, Y.J.1
Björklund, S.2
Li, Y.3
Sayre, M.H.4
-
21
-
-
84923811117
-
The Mediator complex: a central integrator of transcription
-
Allen BL, Taatjes DJ. 2015. The Mediator complex: a central integrator of transcription. Nat Rev Mol Cell Biol 16: 155–66.
-
(2015)
Nat Rev Mol Cell Biol
, vol.16
, pp. 155-166
-
-
Allen, B.L.1
Taatjes, D.J.2
-
22
-
-
80455164640
-
Origins and activity of the Mediator complex
-
Conaway RC, Conaway JW. 2011. Origins and activity of the Mediator complex. Semin Cell Dev Biol 22: 729–34.
-
(2011)
Semin Cell Dev Biol
, vol.22
, pp. 729-734
-
-
Conaway, R.C.1
Conaway, J.W.2
-
23
-
-
60149091656
-
ChIP-seq accurately predicts tissue-specific activity of enhancers
-
Visel A, Blow MJ, Li Z, Zhang T, et al. 2009. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457: 854–8.
-
(2009)
Nature
, vol.457
, pp. 854-858
-
-
Visel, A.1
Blow, M.J.2
Li, Z.3
Zhang, T.4
-
24
-
-
33847334699
-
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
-
Heintzman ND, Stuart RK, Hon G, Fu Y, et al. 2007. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet 39: 311–8.
-
(2007)
Nat Genet
, vol.39
, pp. 311-318
-
-
Heintzman, N.D.1
Stuart, R.K.2
Hon, G.3
Fu, Y.4
-
25
-
-
84929135130
-
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
-
Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, et al. 2015. Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nat Biotechnol 33: 510–7.
-
(2015)
Nat Biotechnol
, vol.33
, pp. 510-517
-
-
Hilton, I.B.1
D'Ippolito, A.M.2
Vockley, C.M.3
Thakore, P.I.4
-
26
-
-
84886084801
-
Locus-specific editing of histone modifications at endogenous enhancers
-
Mendenhall EM, Williamson KE, Reyon D, Zou JY, et al. 2013. Locus-specific editing of histone modifications at endogenous enhancers. Nat Biotechnol 31: 1133–6.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1133-1136
-
-
Mendenhall, E.M.1
Williamson, K.E.2
Reyon, D.3
Zou, J.Y.4
-
27
-
-
84928924333
-
Functional annotation of native enhancers with a Cas9-histone demethylase fusion
-
Kearns NA, Pham H, Tabak B, Genga RM, et al. 2015. Functional annotation of native enhancers with a Cas9-histone demethylase fusion. Nat Methods 12: 401–3.
-
(2015)
Nat Methods
, vol.12
, pp. 401-403
-
-
Kearns, N.A.1
Pham, H.2
Tabak, B.3
Genga, R.M.4
-
28
-
-
84872509787
-
Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation
-
Yu Y, Chen Y, Kim B, Wang H, et al. 2013. Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell 152: 248–61.
-
(2013)
Cell
, vol.152
, pp. 248-261
-
-
Yu, Y.1
Chen, Y.2
Kim, B.3
Wang, H.4
-
29
-
-
84890717859
-
Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
-
Shi J, Whyte WA, Zepeda-Mendoza CJ, Milazzo JP, et al. 2013. Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes Dev 27: 2648–62.
-
(2013)
Genes Dev
, vol.27
, pp. 2648-2662
-
-
Shi, J.1
Whyte, W.A.2
Zepeda-Mendoza, C.J.3
Milazzo, J.P.4
-
30
-
-
84888790012
-
Enhancer transcribed RNAs arise from hypomethylated, Tet-occupied genomic regions
-
Pulakanti K, Pinello L, Stelloh C, Blinka S, et al. 2013. Enhancer transcribed RNAs arise from hypomethylated, Tet-occupied genomic regions. Epigenetics 8: 1303–20.
-
(2013)
Epigenetics
, vol.8
, pp. 1303-1320
-
-
Pulakanti, K.1
Pinello, L.2
Stelloh, C.3
Blinka, S.4
-
31
-
-
80051515081
-
Polycomb eviction as a new distant enhancer function
-
Vernimmen D, Lynch MD, De Gobbi M, Garrick D, et al. 2011. Polycomb eviction as a new distant enhancer function. Genes Dev 25: 1583–8.
-
(2011)
Genes Dev
, vol.25
, pp. 1583-1588
-
-
Vernimmen, D.1
Lynch, M.D.2
De Gobbi, M.3
Garrick, D.4
-
32
-
-
84892392571
-
Polycomb potentiates Meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer
-
Kondo T, Isono K, Kondo K, Endo TA, et al. 2014. Polycomb potentiates Meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer. Dev Cell 28: 94–101.
-
(2014)
Dev Cell
, vol.28
, pp. 94-101
-
-
Kondo, T.1
Isono, K.2
Kondo, K.3
Endo, T.A.4
-
33
-
-
84891478098
-
Chromatin organization and global regulation of Hox gene clusters
-
Montavon T, Duboule D. 2013. Chromatin organization and global regulation of Hox gene clusters. Philos Trans R Soc B Biol Sci 368: 20120367.
-
(2013)
Philos Trans R Soc B Biol Sci
, vol.368
, pp. 20120367
-
-
Montavon, T.1
Duboule, D.2
-
34
-
-
80054110441
-
The dynamic architecture of Hox gene clusters
-
Noordermeer D, Leleu M, Splinter E, Rougemont J, et al. 2011. The dynamic architecture of Hox gene clusters. Science 334: 222–5.
-
(2011)
Science
, vol.334
, pp. 222-225
-
-
Noordermeer, D.1
Leleu, M.2
Splinter, E.3
Rougemont, J.4
-
35
-
-
81855227640
-
A regulatory archipelago controls Hox genes transcription in digits
-
Montavon T, Soshnikova N, Mascrez B, Joye E, et al. 2011. A regulatory archipelago controls Hox genes transcription in digits. Cell 147: 1132–45.
-
(2011)
Cell
, vol.147
, pp. 1132-1145
-
-
Montavon, T.1
Soshnikova, N.2
Mascrez, B.3
Joye, E.4
-
36
-
-
84878754528
-
A switch between topological domains underlies HoxD genes collinearity in mouse limbs
-
Andrey G, Montavon T, Mascrez B, Gonzalez F, et al. 2013. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science 340: 1234167.
-
(2013)
Science
, vol.340
, pp. 1234167
-
-
Andrey, G.1
Montavon, T.2
Mascrez, B.3
Gonzalez, F.4
-
37
-
-
84900414095
-
The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner
-
Williams K, Christensen J, Rappsilber J, Nielsen AL, et al. 2014. The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner. PLoS ONE 9: 9e96545.
-
(2014)
PLoS ONE
, vol.9
-
-
Williams, K.1
Christensen, J.2
Rappsilber, J.3
Nielsen, A.L.4
-
38
-
-
84952639359
-
Polycomb in transcriptional phase transition of developmental genes
-
Kondo T, Ito S, Koseki H. 2016. Polycomb in transcriptional phase transition of developmental genes. Trends Biochem Sci 41: 9–19.
-
(2016)
Trends Biochem Sci
, vol.41
, pp. 9-19
-
-
Kondo, T.1
Ito, S.2
Koseki, H.3
-
39
-
-
84871699564
-
Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
-
Adelman K, Lis JT. 2012. Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans. Nat Rev Genet 13: 720–31.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 720-731
-
-
Adelman, K.1
Lis, J.T.2
-
40
-
-
84894579192
-
Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release
-
Liu W, Ma Q, Wong K, Li W, et al. 2013. Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release. Cell 155: 1581–95.
-
(2013)
Cell
, vol.155
, pp. 1581-1595
-
-
Liu, W.1
Ma, Q.2
Wong, K.3
Li, W.4
-
41
-
-
84876222028
-
Selective inhibition of tumor oncogenes by disruption of super-enhancers
-
Lovén J, Hoke HA, Lin CY, Lau A, et al. 2013. Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell 153: 320–34.
-
(2013)
Cell
, vol.153
, pp. 320-334
-
-
Lovén, J.1
Hoke, H.A.2
Lin, C.Y.3
Lau, A.4
-
42
-
-
84871160931
-
Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells
-
Zhang W, Prakash C, Sum C, Gong Y, et al. 2012. Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells. J Biol Chem 287: 43137–55.
-
(2012)
J Biol Chem
, vol.287
, pp. 43137-43155
-
-
Zhang, W.1
Prakash, C.2
Sum, C.3
Gong, Y.4
-
43
-
-
84881192460
-
BET bromodomains mediate transcriptional pause release in heart failure
-
Anand P, Brown JD, Lin CY, Qi J, et al. 2013. BET bromodomains mediate transcriptional pause release in heart failure. Cell 154: 569–82.
-
(2013)
Cell
, vol.154
, pp. 569-582
-
-
Anand, P.1
Brown, J.D.2
Lin, C.Y.3
Qi, J.4
-
44
-
-
0037131186
-
Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter
-
Eberhardy SR, Farnham PJ. 2002. Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter. J Biol Chem 277: 40156–62.
-
(2002)
J Biol Chem
, vol.277
, pp. 40156-40162
-
-
Eberhardy, S.R.1
Farnham, P.J.2
-
45
-
-
84904785973
-
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis
-
Sabò A, Kress TR, Pelizzola M, de Pretis S, et al. 2014. Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. Nature 511: 488–92.
-
(2014)
Nature
, vol.511
, pp. 488-492
-
-
Sabò, A.1
Kress, T.R.2
Pelizzola, M.3
de Pretis, S.4
-
46
-
-
84872605250
-
The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation
-
Lin C, Garruss AS, Luo Z, Guo F, et al. 2013. The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation. Cell 152: 144–56.
-
(2013)
Cell
, vol.152
, pp. 144-156
-
-
Lin, C.1
Garruss, A.S.2
Luo, Z.3
Guo, F.4
-
47
-
-
84938760450
-
Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization
-
Kaikkonen MU, Niskanen H, Romanoski CE, Kansanen E, et al. 2014. Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization. Nucleic Acids Res 42: 12570–84.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 12570-12584
-
-
Kaikkonen, M.U.1
Niskanen, H.2
Romanoski, C.E.3
Kansanen, E.4
-
48
-
-
0036208492
-
Formation of the androgen receptor transcription complex
-
Shang Y, Myers M, Brown M. 2002. Formation of the androgen receptor transcription complex. Mol Cell 9: 601–10.
-
(2002)
Mol Cell
, vol.9
, pp. 601-610
-
-
Shang, Y.1
Myers, M.2
Brown, M.3
-
49
-
-
0034854577
-
Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter
-
Johnson KD, Christensen HM, Zhao B, Bresnick EH. 2001. Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter. Mol Cell 8: 465–71.
-
(2001)
Mol Cell
, vol.8
, pp. 465-471
-
-
Johnson, K.D.1
Christensen, H.M.2
Zhao, B.3
Bresnick, E.H.4
-
50
-
-
9644302474
-
Recruitment of transcription complexes to the β-globin gene locus in vivo and in vitro
-
Vieira KF, Levings PP, Hill MA, Crusselle VJ, et al. 2004. Recruitment of transcription complexes to the β-globin gene locus in vivo and in vitro. J Biol Chem 279: 50350–7.
-
(2004)
J Biol Chem
, vol.279
, pp. 50350-50357
-
-
Vieira, K.F.1
Levings, P.P.2
Hill, M.A.3
Crusselle, V.J.4
-
51
-
-
77952367798
-
Widespread transcription at neuronal activity-regulated enhancers
-
Kim T-K, Hemberg M, Gray JM, Costa AM, et al. 2010. Widespread transcription at neuronal activity-regulated enhancers. Nature 465: 182–7.
-
(2010)
Nature
, vol.465
, pp. 182-187
-
-
Kim, T.-K.1
Hemberg, M.2
Gray, J.M.3
Costa, A.M.4
-
52
-
-
77952908743
-
A large fraction of extragenic RNA pol II transcription sites overlap enhancers
-
De Santa F, Barozzi I, Mietton F, Ghisletti S, et al. 2010. A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol 8: e1000384.
-
(2010)
PLoS Biol
, vol.8
-
-
De Santa, F.1
Barozzi, I.2
Mietton, F.3
Ghisletti, S.4
-
53
-
-
79961022267
-
Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters
-
Koch F, Fenouil R, Gut M, Cauchy P, et al. 2011. Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Nat Struct Mol Biol 18: 956–63.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 956-963
-
-
Koch, F.1
Fenouil, R.2
Gut, M.3
Cauchy, P.4
-
54
-
-
0037418280
-
Androgen-induced recruitment of RNA polymerase II to a nuclear receptor-p160 coactivator complex
-
Louie MC, Yang HQ, Ma A-H, Xu W, et al. 2003. Androgen-induced recruitment of RNA polymerase II to a nuclear receptor-p160 coactivator complex. Proc Natl Acad Sci USA 100: 2226–30.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2226-2230
-
-
Louie, M.C.1
Yang, H.Q.2
Ma, A.-H.3
Xu, W.4
-
55
-
-
4544330542
-
An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene
-
Zhao H, Dean A. 2004. An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene. Nucleic Acids Res 32: 4903–19.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 4903-4919
-
-
Zhao, H.1
Dean, A.2
-
56
-
-
84899013571
-
Dissecting the function of the adult β-globin downstream promoter region using an artificial zinc finger DNA-binding domain
-
Barrow JJ, Li Y, Hossain M, Huang S, et al. 2014. Dissecting the function of the adult β-globin downstream promoter region using an artificial zinc finger DNA-binding domain. Nucleic Acids Res 42: 4363–74.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 4363-4374
-
-
Barrow, J.J.1
Li, Y.2
Hossain, M.3
Huang, S.4
-
57
-
-
0033215443
-
Looping versus linking: toward a model for long-distance gene activation
-
Bulger M, Groudine M. 1999. Looping versus linking: toward a model for long-distance gene activation. Genes Dev 13: 2465–77.
-
(1999)
Genes Dev
, vol.13
, pp. 2465-2477
-
-
Bulger, M.1
Groudine, M.2
-
58
-
-
84950143919
-
The hierarchy of transcriptional activation: fFrom enhancer to promoter
-
Vernimmen D, Bickmore WA. 2015. The hierarchy of transcriptional activation: fFrom enhancer to promoter. Trends Genet 31: 696–708.
-
(2015)
Trends Genet
, vol.31
, pp. 696-708
-
-
Vernimmen, D.1
Bickmore, W.A.2
-
59
-
-
34548708489
-
A facilitated tracking and transcription mechanism of long-range enhancer function
-
Zhu X, Ling J, Zhang L, Pi W, et al. 2007. A facilitated tracking and transcription mechanism of long-range enhancer function. Nucleic Acids Res 35: 5532–44.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5532-5544
-
-
Zhu, X.1
Ling, J.2
Zhang, L.3
Pi, W.4
-
60
-
-
24044540381
-
Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking
-
Wang Q, Carroll JS, Brown M. 2005. Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking. Mol Cell 19: 631–42.
-
(2005)
Mol Cell
, vol.19
, pp. 631-642
-
-
Wang, Q.1
Carroll, J.S.2
Brown, M.3
-
61
-
-
0026482145
-
Transcription of the hypersensitive site HS2 enhancer in erythroid cells
-
Tuan D, Kong S, Hu K. 1992. Transcription of the hypersensitive site HS2 enhancer in erythroid cells. Proc Natl Acad Sci USA 89: 11219–23.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11219-11223
-
-
Tuan, D.1
Kong, S.2
Hu, K.3
-
62
-
-
14044259362
-
Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage
-
Szutorisz H, Canzonetta C, Georgiou A, Chow C, et al. 2005. Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage. Mol Cell Biol 25: 1804–20.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1804-1820
-
-
Szutorisz, H.1
Canzonetta, C.2
Georgiou, A.3
Chow, C.4
-
63
-
-
33746423865
-
Locus control region transcription plays an active role in long-range gene activation
-
Ho Y, Elefant F, Liebhaber SA, Cooke NE. 2006. Locus control region transcription plays an active role in long-range gene activation. Mol Cell 23: 365–75.
-
(2006)
Mol Cell
, vol.23
, pp. 365-375
-
-
Ho, Y.1
Elefant, F.2
Liebhaber, S.A.3
Cooke, N.E.4
-
64
-
-
0031306463
-
The effect of distance on long-range chromatin interactions
-
Dillon N, Trimborn T, Strouboulis J, Fraser P, et al. 1997. The effect of distance on long-range chromatin interactions. Mol Cell 1: 131–9.
-
(1997)
Mol Cell
, vol.1
, pp. 131-139
-
-
Dillon, N.1
Trimborn, T.2
Strouboulis, J.3
Fraser, P.4
-
65
-
-
0032479079
-
Going the distance: a current view of enhancer action
-
Blackwood EM, Kadonaga JT. 1998. Going the distance: a current view of enhancer action. Science 281: 60–3.
-
(1998)
Science
, vol.281
, pp. 60-63
-
-
Blackwood, E.M.1
Kadonaga, J.T.2
-
66
-
-
0036923739
-
Dynamics of enhancer-promoter communication during differentiation-induced gene activation
-
Hatzis P, Talianidis I. 2002. Dynamics of enhancer-promoter communication during differentiation-induced gene activation. Mol Cell 10: 1467–77.
-
(2002)
Mol Cell
, vol.10
, pp. 1467-1477
-
-
Hatzis, P.1
Talianidis, I.2
-
67
-
-
84861095603
-
Topological domains in mammalian genomes identified by analysis of chromatin interactions
-
Dixon JR, Selvaraj S, Yue F, Kim A, et al. 2012. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 485: 376–80.
-
(2012)
Nature
, vol.485
, pp. 376-380
-
-
Dixon, J.R.1
Selvaraj, S.2
Yue, F.3
Kim, A.4
-
68
-
-
84861100147
-
Spatial partitioning of the regulatory landscape of the X-inactivation centre
-
Nora EP, Lajoie BR, Schulz EG, Giorgetti L, et al. 2012. Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature 485: 381–5.
-
(2012)
Nature
, vol.485
, pp. 381-385
-
-
Nora, E.P.1
Lajoie, B.R.2
Schulz, E.G.3
Giorgetti, L.4
-
69
-
-
84948403758
-
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes
-
Sanborn AL, Rao SSP, Huang S-C, Durand NC, et al. 2015. Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes. Proc Natl Acad Sci USA 112: E6456–65.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E6456-E6465
-
-
Sanborn, A.L.1
Rao, S.S.P.2
Huang, S.-C.3
Durand, N.C.4
-
70
-
-
84919949716
-
A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping
-
Rao SSP, Huntley MH, Durand NC, Stamenova EK, et al. 2014. A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. Cell 159: 1665–80.
-
(2014)
Cell
, vol.159
, pp. 1665-1680
-
-
Rao, S.S.P.1
Huntley, M.H.2
Durand, N.C.3
Stamenova, E.K.4
-
72
-
-
84873456575
-
ERNAs are required for p53-dependent enhancer activity and gene transcription
-
Melo CA, Drost J, Wijchers PJ, van de Werken H, et al. 2013. ERNAs are required for p53-dependent enhancer activity and gene transcription. Mol Cell 49: 524–35.
-
(2013)
Mol Cell
, vol.49
, pp. 524-535
-
-
Melo, C.A.1
Drost, J.2
Wijchers, P.J.3
van de Werken, H.4
-
73
-
-
84879694221
-
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
-
Lam MTY, Cho H, Lesch HP, Gosselin D, et al. 2013. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature 498: 511–5.
-
(2013)
Nature
, vol.498
, pp. 511-515
-
-
Lam, M.T.Y.1
Cho, H.2
Lesch, H.P.3
Gosselin, D.4
-
74
-
-
84874368349
-
Activating RNAs associate with Mediator to enhance chromatin architecture and transcription
-
Lai F, Orom UA, Cesaroni M, Beringer M, et al. 2013. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature 494: 497–501.
-
(2013)
Nature
, vol.494
, pp. 497-501
-
-
Lai, F.1
Orom, U.A.2
Cesaroni, M.3
Beringer, M.4
-
75
-
-
84879695128
-
Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation
-
Li W, Notani D, Ma Q, Tanasa B, et al. 2013. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature 498: 516–20.
-
(2013)
Nature
, vol.498
, pp. 516-520
-
-
Li, W.1
Notani, D.2
Ma, Q.3
Tanasa, B.4
-
76
-
-
84883756441
-
ERNAs promote transcription by establishing chromatin accessibility at defined genomic loci
-
Mousavi K, Zare H, Dell'orso S, Grontved L, et al. 2013. ERNAs promote transcription by establishing chromatin accessibility at defined genomic loci. Mol Cell 51: 606–17.
-
(2013)
Mol Cell
, vol.51
, pp. 606-617
-
-
Mousavi, K.1
Zare, H.2
Dell'orso, S.3
Grontved, L.4
-
77
-
-
84922391291
-
Enhancer RNA facilitates NELF release from immediate early Genes
-
Schaukowitch K, Joo J-Y, Liu X, Watts JK, et al. 2014. Enhancer RNA facilitates NELF release from immediate early Genes. Mol Cell 56: 29–42.
-
(2014)
Mol Cell
, vol.56
, pp. 29-42
-
-
Schaukowitch, K.1
Joo, J.-Y.2
Liu, X.3
Watts, J.K.4
-
78
-
-
84902286789
-
Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes
-
IIott NE, Heward JA, Roux B, Tsitsiou E, et al. 2014. Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes. Nat Commun 5: 3979.
-
(2014)
Nat Commun
, vol.5
, pp. 3979
-
-
IIott, N.E.1
Heward, J.A.2
Roux, B.3
Tsitsiou, E.4
-
79
-
-
84901020399
-
Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation
-
Hsieh C-L, Fei T, Chen Y, Li T, et al. 2014. Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation. Proc Natl Acad Sci USA 111: 7319–24.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 7319-7324
-
-
Hsieh, C.-L.1
Fei, T.2
Chen, Y.3
Li, T.4
-
80
-
-
84947766170
-
Transcription factor trapping by RNA in gene regulatory elements
-
Sigova AA, Abraham BJ, Ji X, Molinie B, et al. 2015. Transcription factor trapping by RNA in gene regulatory elements. Science 350: 978–81.
-
(2015)
Science
, vol.350
, pp. 978-981
-
-
Sigova, A.A.1
Abraham, B.J.2
Ji, X.3
Molinie, B.4
-
81
-
-
84957654693
-
Regulated formation of lncRNA-DNA hybrids enables faster transcriptional induction and environmental adaptation
-
Cloutier SC, Wang S, Ma WK, Al Husini N, et al. 2016. Regulated formation of lncRNA-DNA hybrids enables faster transcriptional induction and environmental adaptation. Mol Cell 61: 393–404.
-
(2016)
Mol Cell
, vol.61
, pp. 393-404
-
-
Cloutier, S.C.1
Wang, S.2
Ma, W.K.3
Al Husini, N.4
-
82
-
-
84920954858
-
Nuclear stability and transcriptional directionality separate functionally distinct RNA species
-
Andersson R, Refsing Andersen P, Valen E, Core LJ, et al. 2014. Nuclear stability and transcriptional directionality separate functionally distinct RNA species. Nat Commun 5: 5336.
-
(2014)
Nat Commun
, vol.5
, pp. 5336
-
-
Andersson, R.1
Refsing Andersen, P.2
Valen, E.3
Core, L.J.4
-
83
-
-
84940419156
-
Integrator mediates the biogenesis of enhancer RNAs
-
Lai F, Gardini A, Zhang A, Shiekhattar R. 2015. Integrator mediates the biogenesis of enhancer RNAs. Nature 525: 399–403.
-
(2015)
Nature
, vol.525
, pp. 399-403
-
-
Lai, F.1
Gardini, A.2
Zhang, A.3
Shiekhattar, R.4
-
84
-
-
84962129303
-
Unlinking an lncRNA from its associated cis element
-
Paralkar VR, Taborda CC, Huang P, Yao Y, et al. 2016. Unlinking an lncRNA from its associated cis element. Mol Cell 62: 104–10.
-
(2016)
Mol Cell
, vol.62
, pp. 104-110
-
-
Paralkar, V.R.1
Taborda, C.C.2
Huang, P.3
Yao, Y.4
-
86
-
-
84855508402
-
Enhancers and silencers: an integrated and simple model for their function
-
Kolovos P, Knoch TA, Grosveld FG, Cook PR, et al. 2012. Enhancers and silencers: an integrated and simple model for their function. Epigenetics Chromatin 5: 1–8.
-
(2012)
Epigenetics Chromatin
, vol.5
, pp. 1-8
-
-
Kolovos, P.1
Knoch, T.A.2
Grosveld, F.G.3
Cook, P.R.4
-
87
-
-
84862908850
-
Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation
-
Li G, Ruan X, Auerbach RK, Sandhu KS, et al. 2012. Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell 148: 84–98.
-
(2012)
Cell
, vol.148
, pp. 84-98
-
-
Li, G.1
Ruan, X.2
Auerbach, R.K.3
Sandhu, K.S.4
-
88
-
-
84938287359
-
A unified architecture of transcriptional regulatory elements
-
Andersson R, Sandelin A, Danko CG. 2015. A unified architecture of transcriptional regulatory elements. Trends Genet 31: 426–33.
-
(2015)
Trends Genet
, vol.31
, pp. 426-433
-
-
Andersson, R.1
Sandelin, A.2
Danko, C.G.3
-
89
-
-
33747072322
-
Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster
-
Moorman C, Sun LV, Wang J, de Wit E, et al. 2006. Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster. Proc Natl Acad Sci USA 103: 12027–32.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12027-12032
-
-
Moorman, C.1
Sun, L.V.2
Wang, J.3
de Wit, E.4
-
90
-
-
84886780296
-
Dynamic trans-acting factor colocalization in human cells
-
Xie D, Boyle AP, Wu L, Zhai J, et al. 2013. Dynamic trans-acting factor colocalization in human cells. Cell 155: 713–24.
-
(2013)
Cell
, vol.155
, pp. 713-724
-
-
Xie, D.1
Boyle, A.P.2
Wu, L.3
Zhai, J.4
-
91
-
-
84923345330
-
An integrative analysis of TFBS-clustered regions reveals new transcriptional regulation models on the accessible chromatin landscape
-
Chen H, Li H, Liu F, Zheng X, et al. 2015. An integrative analysis of TFBS-clustered regions reveals new transcriptional regulation models on the accessible chromatin landscape. Sci Rep 5: 8465.
-
(2015)
Sci Rep
, vol.5
, pp. 8465
-
-
Chen, H.1
Li, H.2
Liu, F.3
Zheng, X.4
-
92
-
-
84860503075
-
HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature
-
Kvon EZ, Stampfel G, Yanez-Cuna JO, Dickson BJ, et al. 2012. HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature. Genes Dev 26: 908–13.
-
(2012)
Genes Dev
, vol.26
, pp. 908-913
-
-
Kvon, E.Z.1
Stampfel, G.2
Yanez-Cuna, J.O.3
Dickson, B.J.4
-
93
-
-
84883457107
-
Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model
-
Smith RP, Taher L, Patwardhan RP, Kim MJ, et al. 2013. Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model. Nat Genet 45: 1021–8.
-
(2013)
Nat Genet
, vol.45
, pp. 1021-1028
-
-
Smith, R.P.1
Taher, L.2
Patwardhan, R.P.3
Kim, M.J.4
-
94
-
-
84983426403
-
Integrating regulatory information via combinatorial control of the transcription cycle
-
Scholes C, DePace AH, Sanchez A. 2016. Integrating regulatory information via combinatorial control of the transcription cycle. bioRxiv, doi: 10.1101/039339
-
(2016)
bioRxiv
-
-
Scholes, C.1
DePace, A.H.2
Sanchez, A.3
-
95
-
-
84902810053
-
In pursuit of design principles of regulatory sequences
-
Levo M, Segal E. 2014. In pursuit of design principles of regulatory sequences. Nat Rev Genet 15: 453–68.
-
(2014)
Nat Rev Genet
, vol.15
, pp. 453-468
-
-
Levo, M.1
Segal, E.2
-
96
-
-
84939265529
-
Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences
-
White MA. 2015. Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences. Genomics 106: 165–70.
-
(2015)
Genomics
, vol.106
, pp. 165-170
-
-
White, M.A.1
-
97
-
-
84939255435
-
Decoding enhancers using massively parallel reporter assays
-
Inoue F, Ahituv N. 2015. Decoding enhancers using massively parallel reporter assays. Genomics 106: 159–64.
-
(2015)
Genomics
, vol.106
, pp. 159-164
-
-
Inoue, F.1
Ahituv, N.2
-
98
-
-
84863230316
-
Massively parallel functional dissection of mammalian enhancers in vivo
-
Patwardhan RP, Hiatt JB, Witten DM, Kim MJ, et al. 2012. Massively parallel functional dissection of mammalian enhancers in vivo. Nat Biotechnol 30: 265–70.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 265-270
-
-
Patwardhan, R.P.1
Hiatt, J.B.2
Witten, D.M.3
Kim, M.J.4
-
99
-
-
84874381107
-
Genome-wide quantitative enhancer activity maps identified by STARR-seq
-
Arnold CD, Gerlach D, Stelzer C, Boryn LM, et al. 2013. Genome-wide quantitative enhancer activity maps identified by STARR-seq. Science 339: 1074–7.
-
(2013)
Science
, vol.339
, pp. 1074-1077
-
-
Arnold, C.D.1
Gerlach, D.2
Stelzer, C.3
Boryn, L.M.4
-
100
-
-
84869853147
-
Complex effects of nucleotide variants in a mammalian cis-regulatory element
-
Kwasnieski JC, Mogno I, Myers CA, Corbo JC, et al. 2012. Complex effects of nucleotide variants in a mammalian cis-regulatory element. Proc Natl Acad Sci USA 109: 19498–503.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 19498-19503
-
-
Kwasnieski, J.C.1
Mogno, I.2
Myers, C.A.3
Corbo, J.C.4
-
101
-
-
84862002321
-
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
-
Sharon E, Kalma Y, Sharp A, Raveh-Sadka T, et al. 2012. Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters. Nat Biotechnol 30: 521–30.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 521-530
-
-
Sharon, E.1
Kalma, Y.2
Sharp, A.3
Raveh-Sadka, T.4
-
102
-
-
84899670369
-
FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells
-
Murtha M, Tokcaer-Keskin Z, Tang Z, Strino F, et al. 2014. FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells. Nat Methods 11: 559–65.
-
(2014)
Nat Methods
, vol.11
, pp. 559-565
-
-
Murtha, M.1
Tokcaer-Keskin, Z.2
Tang, Z.3
Strino, F.4
-
103
-
-
84899692444
-
Function-based identification of mammalian enhancers using site-specific integration
-
Dickel DE, Zhu Y, Nord AS, Wylie JN, et al. 2014. Function-based identification of mammalian enhancers using site-specific integration. Nat Methods 11: 566–71.
-
(2014)
Nat Methods
, vol.11
, pp. 566-571
-
-
Dickel, D.E.1
Zhu, Y.2
Nord, A.S.3
Wylie, J.N.4
-
104
-
-
84882737017
-
Chromatin position effects assayed by thousands of reporters integrated in parallel
-
Akhtar W, de Jong J, Pindyurin AV, Pagie L, et al. 2013. Chromatin position effects assayed by thousands of reporters integrated in parallel. Cell 154: 914–27.
-
(2013)
Cell
, vol.154
, pp. 914-927
-
-
Akhtar, W.1
de Jong, J.2
Pindyurin, A.V.3
Pagie, L.4
-
105
-
-
84863229330
-
Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay
-
Melnikov A, Murugan A, Zhang X, Tesileanu T, et al. 2012. Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay. Nat Biotechnol 30: 271–7.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 271-277
-
-
Melnikov, A.1
Murugan, A.2
Zhang, X.3
Tesileanu, T.4
-
106
-
-
84877147962
-
Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay
-
Kheradpour P, Ernst J, Melnikov A, Rogov P, et al. 2013. Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay. Genome Res 23: 800–11.
-
(2013)
Genome Res
, vol.23
, pp. 800-811
-
-
Kheradpour, P.1
Ernst, J.2
Melnikov, A.3
Rogov, P.4
-
107
-
-
71849118573
-
High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
-
Patwardhan RP, Lee C, Litvin O, Young DL, et al. 2009. High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis. Nat Biotechnol 27: 1173–5.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 1173-1175
-
-
Patwardhan, R.P.1
Lee, C.2
Litvin, O.3
Young, D.L.4
-
108
-
-
84881442078
-
Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos
-
Gisselbrecht SS, Barrera LA, Porsch M, Aboukhalil A, et al. 2013. Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos. Nat Methods 10: 774–80.
-
(2013)
Nat Methods
, vol.10
, pp. 774-780
-
-
Gisselbrecht, S.S.1
Barrera, L.A.2
Porsch, M.3
Aboukhalil, A.4
-
109
-
-
84928136624
-
High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq
-
Vanhille L, Griffon A, Maqbool MA, Zacarias-Cabeza J, et al. 2015. High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq. Nat Commun 6: 6905.
-
(2015)
Nat Commun
, vol.6
, pp. 6905
-
-
Vanhille, L.1
Griffon, A.2
Maqbool, M.A.3
Zacarias-Cabeza, J.4
-
110
-
-
84946925193
-
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
-
Canver MC, Smith EC, Sher F, Pinello L, et al. 2015. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature 527: 192–7.
-
(2015)
Nature
, vol.527
, pp. 192-197
-
-
Canver, M.C.1
Smith, E.C.2
Sher, F.3
Pinello, L.4
-
111
-
-
0030960672
-
Transcriptional activation by recruitment
-
Ptashne M, Gann A. 1997. Transcriptional activation by recruitment. Nature 386: 569–77.
-
(1997)
Nature
, vol.386
, pp. 569-577
-
-
Ptashne, M.1
Gann, A.2
-
112
-
-
84949196425
-
Transcriptional regulators form diverse groups with context-dependent regulatory functions
-
Stampfel G, Kazmar T, Frank O, Wienerroither S, et al. 2015. Transcriptional regulators form diverse groups with context-dependent regulatory functions. Nature 528: 1–8.
-
(2015)
Nature
, vol.528
, pp. 1-8
-
-
Stampfel, G.1
Kazmar, T.2
Frank, O.3
Wienerroither, S.4
-
113
-
-
84903942172
-
Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulation
-
Keung AJ, Bashor CJ, Kiriakov S, Collins JJ, et al. 2014. Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulation. Cell 158: 110–20.
-
(2014)
Cell
, vol.158
, pp. 110-120
-
-
Keung, A.J.1
Bashor, C.J.2
Kiriakov, S.3
Collins, J.J.4
-
114
-
-
84960387483
-
A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening
-
Diao Y, Li B, Meng Z, Jung I, et al. 2016. A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. Genome Res 26: 397–405.
-
(2016)
Genome Res
, vol.26
, pp. 397-405
-
-
Diao, Y.1
Li, B.2
Meng, Z.3
Jung, I.4
-
115
-
-
84907257107
-
Saturation editing of genomic regions by multiplex homology-directed repair
-
Findlay GM, Boyle EA, Hause RJ, Klein JC, et al. 2014. Saturation editing of genomic regions by multiplex homology-directed repair. Nature 513: 120–3.
-
(2014)
Nature
, vol.513
, pp. 120-123
-
-
Findlay, G.M.1
Boyle, E.A.2
Hause, R.J.3
Klein, J.C.4
-
116
-
-
84961226910
-
Programmable RNA tracking in live cells with CRISPR/Cas9
-
Nelles DA, Fang MY, O'Connell MR, Xu JL, et al. 2016. Programmable RNA tracking in live cells with CRISPR/Cas9. Cell 165: 488–96.
-
(2016)
Cell
, vol.165
, pp. 488-496
-
-
Nelles, D.A.1
Fang, M.Y.2
O'Connell, M.R.3
Xu, J.L.4
-
117
-
-
84894063115
-
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system
-
Chen B, Gilbert LA, Cimini BA, Schnitzbauer J, et al. 2013. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell 155: 1479–91.
-
(2013)
Cell
, vol.155
, pp. 1479-1491
-
-
Chen, B.1
Gilbert, L.A.2
Cimini, B.A.3
Schnitzbauer, J.4
-
118
-
-
84966908028
-
Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow
-
Ma H, Tu L-C, Naseri A, Huisman M, et al. 2016. Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow. Nat Biotechnol 34: 528–30.
-
(2016)
Nat Biotechnol
, vol.34
, pp. 528-530
-
-
Ma, H.1
Tu, L.-C.2
Naseri, A.3
Huisman, M.4
-
119
-
-
84884906690
-
RNA-guided gene activation by CRISPR-Cas9-based transcription factors
-
Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, et al. 2013. RNA-guided gene activation by CRISPR-Cas9-based transcription factors. Nat Methods 10: 973–6.
-
(2013)
Nat Methods
, vol.10
, pp. 973-976
-
-
Perez-Pinera, P.1
Kocak, D.D.2
Vockley, C.M.3
Adler, A.F.4
-
120
-
-
84920992414
-
Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds
-
Zalatan JG, Lee ME, Almeida R, Gilbert LA, et al. 2015. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell 160: 339–50.
-
(2015)
Cell
, vol.160
, pp. 339-350
-
-
Zalatan, J.G.1
Lee, M.E.2
Almeida, R.3
Gilbert, L.A.4
-
121
-
-
84934267574
-
Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display
-
Shechner DM, Hacisuleyman E, Younger ST, Rinn JL. 2015. Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display. Nat Methods 12: 664–70.
-
(2015)
Nat Methods
, vol.12
, pp. 664-670
-
-
Shechner, D.M.1
Hacisuleyman, E.2
Younger, S.T.3
Rinn, J.L.4
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