Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma

OncoImmunology

Volumn 5, Issue 8, 2016, Pages

  Penny, Hweixian Leong ^a   Sieow, Je Lin ^a   Adriani, Giulia ^b   Yeap, Wei Hseun ^a   See Chi Ee, Peter ^a   San Luis, Boris ^a   Lee, Bernett ^a   Lee, Terence ^c   Mak, Shi Ya ^d   Ho, Ying Swan ^d   Lam, Kong Peng ^d   Ong, Choon Kiat ^e   Huang, Ruby Y J ^f   Ginhoux, Florent ^a   Rotzschke, Olaf ^a   Kamm, Roger D ^b,g   Wong, Siew Cheng ^a  

^a AGENCY FOR SCIENCE   (Singapore)

^b SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^c Raffles Science Institution   (Singapore)

^d AGENCY FOR SCIENCE   (Singapore)

^e DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g Massachusetts Institute of Technology   (United States)

Author keywords

macrophages; Metabolism; metastasis; pancreatic cancer

Indexed keywords

DEOXYGLUCOSE; GLYCOLYTIC ENZYME; HEXOKINASE 2; PEPTIDES AND PROTEINS; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CELL INFILTRATION; CELL SELECTION; CONTROLLED STUDY; DNA TRANSCRIPTION; ENDOCYTOSIS; FLOW CYTOMETRY; GENE OVEREXPRESSION; GLYCOLYSIS; HUMAN; HUMAN CELL; MACROPHAGE; MAGNETIC AUTOMATED CELL SORTING; METABOLIC FLUX ANALYSIS; METABOLISM; METABOLOMICS; METASTASIS; MONOCYTE CULTURE; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PANCREAS ADENOCARCINOMA; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEADY STATE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR CELL; UMBILICAL VEIN ENDOTHELIAL CELL; WARBURG METABOLISM;

EID: 84981555713     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2016.1191731     Document Type: Article

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