Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 34, 2012, Pages 13515-13520

  Zervantonakis, Ioannis K ^a   Hughes Alford, Shannon K ^a,b   Charest, Joseph L ^c   Condeelis, John S ^d   Gertler, Frank B ^b   Kamm, Roger D ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c CHARLES STARK DRAPER LABORATORY   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

3D microfluidics; Cancer migration; Cancer endothelial cell interactions; In vitro; Transmigration

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CARCINOMA CELL; CELL ACTIVATION; CELL INTERACTION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; FIBROSARCOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MACROPHAGE; MEMBRANE PERMEABILITY; MICROFLUIDICS; PARACRINE SIGNALING; PRIORITY JOURNAL; TUMOR CELL; TUMOR CELL INTRAVASATION; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION; VASCULAR ENDOTHELIUM;

CELL COMMUNICATION; CELL LINE, TUMOR; CELL MOVEMENT; ENDOTHELIAL CELLS; HUMANS; HYDROGEL; IMAGING, THREE-DIMENSIONAL; MACROPHAGES; MICROFLUIDICS; NEOPLASM METASTASIS; NEOPLASMS; PERMEABILITY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84865293346     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210182109     Document Type: Article

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