Contact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and ß2 integrin interactions

Oncotarget

Volumn 6, Issue 28, 2015, Pages 25295-25307

  Bai, Jing ^a,b   Adriani, Giulia ^a   Dang, Truong Minh ^c   Tu, Ting Yuan ^a   Penny, Hwei Xian Leong ^c   Wong, Siew Cheng ^c   Kamm, R D Roger D ^a,b   Thiery, Jean Paul ^a,d,e  

^a SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^b Massachusetts Institute of Technology   (United States)

^c AGENCY FOR SCIENCE   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

cancer microenvironment; Epithelial mesenchymal transition; macrophage phenotypes; macrophage polarization; microfluidics

Indexed keywords

CD18 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; HYDROGEL; ICAM1 PROTEIN, HUMAN;

ARTICLE; CELL AGGREGATION; CELL CONTACT; CELL DIFFERENTIATION; CELL INFILTRATION; COCULTURE; CONTROLLED STUDY; DISPERSION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ADENOCARCINOMA; LUNG CANCER CELL LINE; MACROPHAGE; MACROPHAGE MIGRATION; MICROFLUIDIC ANALYSIS; PROTEIN PROTEIN INTERACTION; TUMOR MICROENVIRONMENT; UMBILICAL VEIN ENDOTHELIAL CELL; ADENOCARCINOMA; CELL COMMUNICATION; CELL MOTION; GENETIC TRANSFECTION; GENETICS; HYDROGEL; LAB ON A CHIP; LUNG TUMOR; METABOLISM; PATHOLOGY; PHENOTYPE; SECONDARY; SIGNAL TRANSDUCTION; TIME FACTOR; TUMOR CELL LINE;

ADENOCARCINOMA; ANTIGENS, CD18; CELL COMMUNICATION; CELL LINE, TUMOR; CELL MOVEMENT; COCULTURE TECHNIQUES; EPITHELIAL-MESENCHYMAL TRANSITION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGELS; INTERCELLULAR ADHESION MOLECULE-1; LAB-ON-A-CHIP DEVICES; LUNG NEOPLASMS; MACROPHAGES; PHENOTYPE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR MICROENVIRONMENT;

EID: 84944463517     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4716     Document Type: Article

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