Cooperation of adenosine with macrophage toll-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19247-19258

  Ruiz García, Almudena ^a   Monsalve, Eva ^a   Novellasdemunt, Laura ^b   Navarro Sabaté, Áurea ^b   Manzano, Anna ^b   Rivero, Samuel ^a   Castrillo, Antonio ^c   Casado, Marta ^d   Laborda, Jorge ^a   Bartrons, Ramón ^b   Díaz Guerra, María José M ^a  

^a University of Castilla La Mancha   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^d INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE RECEPTOR; ATP GENERATION; DELETION ANALYSIS; DIFFERENTIAL EXPRESSIONS; GLYCOLYTIC FLUX; LONG TERM; MACROPHAGE ACTIVATION; PROMOTER SEQUENCES; SITE DIRECTED MUTAGENESIS;

FRUCTOSE; GENES; PHOSPHORYLATION; TRANSCRIPTION; TRANSCRIPTION FACTORS;

MACROPHAGES;

ADENOSINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENYLATE KINASE; FRUCTOSE 2,6 BISPHOSPHATASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIPOPOLYSACCHARIDE; PHOSPHOTRANSFERASE; PROTEIN PFKFB3; SHORT HAIRPIN RNA; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE; GENE DELETION; GENE EXPRESSION; GENE INDUCTION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PFKFB3 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS;

ADENOSINE; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; FRUCTOSEDIPHOSPHATES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOLYSIS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOENZYMES; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; MUTAGENESIS, SITE-DIRECTED; PHOSPHOFRUCTOKINASE-2; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A2B; SEQUENCE DELETION; SP1 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 4;

BACTERIA (MICROORGANISMS);

EID: 79957587060     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.190298     Document Type: Article

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